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• 3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics

  Abdollahi Govar, A., Törő, G., Szaniszlo, P., Pavlidou, A., Bibli, S. I., Thanki, K., Resto, V. A., Chao, C., Hellmich, M. R., Szabo, C., Papapetropoulos, A. & Módis, K., Feb 1 2020, In: British Journal of Pharmacology. 177, 4, p. 866-883 18 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-mercaptopyruvic acid
  • Energy Metabolism
  • Endothelial Cells
  • Hydrogen Sulfide
  • Small Interfering RNA
  7 Scopus citations

• Apigenin Decreases Acinar Cell Damage in Pancreatitis

  Mrazek, A. A., Bhatia, V., Falzon, M., Spratt, H., Chao, C. & Hellmich, M. R., May 1 2019, In: Pancreas. 48, 5, p. 711-718 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Apigenin
  • Acinar Cells
  • Pancreatitis
  • Parathyroid Hormone-Related Protein
  • Transforming Growth Factors
  2 Scopus citations

• Apigenin inhibits pancreatic stellate cell activity in pancreatitis

  Mrazek, A. A., Porro, L. J., Bhatia, V., Falzon, M., Spratt, H., Zhou, J., Chao, C. & Hellmich, M. R., Jun 1 2015, In: Journal of Surgical Research. 196, 1, p. 8-16 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatic Stellate Cells
  • Apigenin
  • Pancreatitis
  • Chronic Pancreatitis
  • Fibrosis
  23 Scopus citations

• Cystathionine-β-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach

  Chao, C., Zatarain, J. R., Ding, Y., Coletta, C., Mrazek, A. A., Druzhyna, N., Johnson, P., Chen, H., Hellmich, J. L., Asimakopoulou, A., Yanagi, K., Olah, G., Szoleczky, P., Törö, G., Bohanon, F. J., Cheema, M., Lewis, R., Eckelbarger, D., Ahmad, A., Módis, K. & 6 others, Untereiner, A., Szczesny, B., Papapetropoulos, A., Zhou, J., Hellmich, M. R. & Szabo, C., 2016, In: Molecular Medicine. 22, p. 361-379 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Aminooxyacetic Acid
  • Cystathionine
  • Prodrugs
  • Colonic Neoplasms
  • Neoplasms
  24 Scopus citations

• Gremlin is a key pro-fibrogenic factor in chronic pancreatitis

  Staloch, D., Gao, X., Liu, K., Xu, M., Feng, X., Aronson, J. F., Falzon, M., Greeley, G. H., Rastellini, C., Chao, C., Hellmich, M. R., Cao, Y. & Ko, T. C., Oct 3 2015, In: Journal of Molecular Medicine. 93, 10, p. 1085-1093 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Chronic Pancreatitis
  • Bone Morphogenetic Proteins
  • Transforming Growth Factors
  • Pancreatic Stellate Cells
  • Mouse Grem1 protein
  22 Scopus citations

• Isolation of CD 90+ fibroblast/myofibroblasts from human frozen gastrointestinal specimens

  Johnson, P., Beswick, E. J., Chao, C., Powell, D. W., Hellmich, M. R. & Pinchuk, I. V., Jan 31 2016, In: Journal of Visualized Experiments. 2016, 107, e53691.

  Research output: Contribution to journal › Article › peer-review

  • Fibroblasts
  • Myofibroblasts
  • Tissue
  • Immunohistochemistry
  • Flow cytometry
  9 Scopus citations

• Malignant phyllodes tumor of the breast: A case report

  Al-Zoubaidi, M., Qiu, S., Bonnen, M., Joyner, M., Roehl, K., Silva, C. & Chao, C., 2011, In: Open Breast Cancer Journal. 3, p. 45-48 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Phyllodes Tumor
  • Breast Neoplasms
  • Stromal Cells
  • Breast
  2 Scopus citations

• Medical Students’ Evaluation of Scientific Evidence and Their Justifications for Their Clinical Decisions: a Pilot Study

  Cestone, C., Lewis, R., Aronson, J. F. & Chao, C., Dec 15 2018, In: Medical Science Educator. 28, 4, p. 587-590 4 p.

  Research output: Contribution to journal › Article › peer-review

  • clinical decisions
  • Medical Students
  • medical student
  • Clinical Decision-Making
  • evaluation

• Pharmacological inhibition and genetic knockdown of exchange protein directly activated by cAMP 1 reduce pancreatic cancer metastasis in vivos

  Almahariq, M., Chao, C., Mei, F. C., Hellmich, M. R., Patrikeev, I., Motamedi, M. & Cheng, X., Feb 1 2015, In: Molecular pharmacology. 87, 2, p. 142-149 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatic Neoplasms
  • Adenocarcinoma
  • Pharmacology
  • Neoplasm Metastasis
  • Proteins
  28 Scopus citations

• Regulation of bombesin-stimulated cyclooxygenase-2 expression in prostate cancer cells

  Wen, X., Chao, C., Ives, K. & Hellmich, M. R., Jul 11 2011, In: BMC Molecular Biology. 12, 29.

  Research output: Contribution to journal › Article › peer-review

  • Bombesin
  • Cyclooxygenase 2
  • Prostatic Neoplasms
  • Phosphatidylinositol 3-Kinases
  • NF-kappa B
  8 Scopus citations

• Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer

  Druzhyna, N., Szczesny, B., Olah, G., Módis, K., Asimakopoulou, A., Pavlidou, A., Szoleczky, P., Gerö, D., Yanagi, K., Törö, G., López-García, I., Myrianthopoulos, V., Mikros, E., Zatarain, J. R., Chao, C., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Nov 1 2016, In: Pharmacological Research. 113, p. 18-37 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Benserazide
  • Cystathionine
  • Investigational Therapies
  • Inhibitory Concentration 50
  • Colonic Neoplasms
  29 Scopus citations

• The therapeutic potential of cystathionine β-Synthetase/hydrogen sulfide inhibition in cancer

  Hellmich, M. R., Coletta, C., Chao, C. & Szabo, C., Feb 10 2015, In: Antioxidants and Redox Signaling. 22, 5, p. 424-448 25 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cystathionine beta-Synthase
  • Hydrogen Sulfide
  • Cells
  • Tumors
  • Energy Metabolism
  114 Scopus citations