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• Alkhumra, not alkhurma, is the correct name of the new hemorrhagic fever flavivirus identified in Saudi Arabia

  Madani, T. A., Azhar, E. I., Abuelzein, E. T. M. E., Kao, M., Al-Bar, H. M. S., Niedrig, M. & Ksiazek, T. G., Apr 1 2012, In: Intervirology. 55, 4, p. 259-260 2 p.

  Research output: Contribution to journal › Letter › peer-review
  13 Scopus citations

• Annexin a2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and ebola virus infections

  Su, Z., Chang, Q., Drelich, A., Shelite, T., Judy, B., Liu, Y., Xiao, J., Zhou, C., He, X., Jin, Y., Saito, T., Tang, S., Soong, L., Wakamiya, M., Fang, X., Bukreyev, A., Ksiazek, T., Russell, W. K. & Gong, B., Jul 2020, In: PLoS neglected tropical diseases. 14, 7, p. 1-30 30 p., e0007960.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Annexin A2
  • Rickettsia
  • Ebola Hemorrhagic Fever
  • Annexins
  • Knockout Mice

• A practical strategy for immunofluorescent detecting multiple targets in mouse tissues without restrictions on the host specious resources of the primary antibodies

  Yu, S., He, X., Drelich, A., Judy, B., Chang, Q., Cao, S., Ksiazek, T., Xu, Z. & Gong, B., May 2019, In: Pathology Research and Practice. 215, 5, p. 1049-1053 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Rabbits
  • Antibodies
  • Direct Fluorescent Antibody Technique
  • Indirect Fluorescent Antibody Technique
  • Antigens
  1 Scopus citations

• Baseline mapping of Lassa fever virology, epidemiology and vaccine research and development review-article

  Hallam, H. J., Hallam, S., Rodriguez, S. E., Barrett, A. D. T., Beasley, D. W. C., Chua, A., Ksiazek, T. G., Milligan, G. N., Sathiyamoorthy, V. & Reece, L. M., Dec 1 2018, In: npj Vaccines. 3, 1, 11.

  Research output: Contribution to journal › Article › peer-review

  • Lassa Fever
  • Lassa virus
  • Virology
  • Epidemiology
  • Vaccines
  33 Scopus citations

• Bilateral entry and release of middle east respiratory syndrome coronavirus induces profound apoptosis of human bronchial epithelial cells

  Tao, X., Hill, T. E., Morimoto, C., Peters, C. J., Ksiazek, T. G. & Tseng, C. T. K., 2013, In: Journal of virology. 87, 17, p. 9953-9958 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Middle East respiratory syndrome coronavirus
  • Middle East Respiratory Syndrome Coronavirus
  • Severe Acute Respiratory Syndrome
  • apoptosis
  • epithelial cells
  37 Scopus citations

• Blocking of exchange proteins directly activated by cAMP leads to reduced replication of middle east respiratory syndrome coronavirus

  Tao, X., Mei, F., Agrawal, A., Peters, C. J., Ksiazek, T., Cheng, X. & Tseng, C-T., Jan 1 2014, In: Journal of Virology. 88, 7, p. 3902-3910 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Middle East respiratory syndrome coronavirus
  • Middle East Respiratory Syndrome Coronavirus
  • Coronavirus Infections
  • infection
  • therapeutics

• Blocking of exchange proteins directly activated by cAMP leads to reduced replication of middle east respiratory syndrome coronavirus

  Tao, X., Mei, F., Agrawal, A., Peters, C. J., Ksiazek, T. G., Cheng, X. & Tseng, C. T. K., Apr 2014, In: Journal of virology. 88, 7, p. 3902-3910 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Middle East respiratory syndrome coronavirus
  • Middle East Respiratory Syndrome Coronavirus
  • Coronavirus Infections
  • infection
  • therapeutics
  28 Scopus citations

• Broadly neutralizing antibodies from human survivors target a conserved site in the ebola virus glycoprotein hr2-mper region

  Flyak, A. I., Kuzmina, N., Murin, C. D., Bryan, C., Davidson, E., Gilchuk, P., Gulka, C. P., Ilinykh, P. A., Shen, X., Huang, K., Ramanathan, P., Turner, H., Fusco, M. L., Lampley, R., Kose, N., King, H., Sapparapu, G., Doranz, B. J., Ksiazek, T. G., Wright, D. W. & 4 others, Saphire, E. O., Ward, A. B., Bukreyev, A. & Crowe, J. E., Jun 1 2018, In: Nature Microbiology. 3, 6, p. 670-677 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • ZMapp
  • Neutralizing Antibodies
  • Survivors
  • Glycoproteins
  27 Scopus citations

• Cell culture and electron microscopy for identifying viruses in diseases of unknown cause

  Goldsmith, C. S., Ksiazek, T. G., Rollin, P. E., Comer, J. A., Nicholson, W. L., Peret, T. C. T., Erdman, D. D., Bellini, W. J., Harcourt, B. H., Rota, P. A., Bhatnagar, J., Bowen, M. D., Erickson, B. R., McMullan, L. K., Nichol, S. T., Shieh, W. J., Paddock, C. D. & Zaki, S. R., Jun 1 2013, In: Emerging infectious diseases. 19, 6, p. 886-891 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Bunyamwera virus
  • Lymphocytic Choriomeningitis
  • Electron Microscopy
  • Cell Culture Techniques
  • Virus Diseases
  25 Scopus citations

• Chimeric filoviruses for identification and characterization of monoclonal antibodies

  Ilinykh, P. A., Shen, X., Flyak, A. I., Kuzmina, N., Ksiazek, T. G., Crowe, J. E. & Bukreyev, A., Apr 1 2016, In: Journal of virology. 90, 8, p. 3890-3901 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Filoviridae
  • monoclonal antibodies
  • Monoclonal Antibodies
  • Ebolavirus
  • Glycoproteins
  22 Scopus citations

• Comparison of RT-PCR assay and virus isolation in cell culture for the detection of alkhumra hemorrhagic fever virus

  Madani, T. A., Abuelzein, E. T. M. E., Azhar, E. I., Al-Bar, H. M. S., Abu-Araki, H. & Ksiazek, T. G., Jul 2014, In: Journal of Medical Virology. 86, 7, p. 1176-1180 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Culture Techniques
  • Fever
  • Viruses
  • Polymerase Chain Reaction
  • Cell Line
  3 Scopus citations

• Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: Evidence of possible mediation by host tRNA-derived small noncoding RNAs

  Gong, B., Lee, Y. S., Lee, I., Shelite, T. R., Kunkeaw, N., Xu, G., Lee, K., Jeon, S. H., Johnson, B. H., Chang, Q., Ha, T., Mendell, N. L., Cheng, X., Bouyer, D. H., Boor, P. J., Ksiazek, T. G. & Walker, D. H., Jun 23 2013, In: BMC Infectious Diseases. 13, 1, 285.

  Research output: Contribution to journal › Article › peer-review

  • angiogenin
  • Spotted Fever Group Rickettsiosis
  • Rickettsia
  • Small Untranslated RNA
  • Transfer RNA
  25 Scopus citations

• Complete genome sequences of a hantavirus isolate from New York

  McMullan, L. K., Albariño, C. G., Ksiazek, T. G., Nichol, S. T. & Spiropoulou, C. F., Mar 1 2018, In: Genome Announcements. 6, 12, e00188-18.

  Research output: Contribution to journal › Article › peer-review

  • Hantavirus
  • Peromyscus
  • Genome
  • Canada
  3 Scopus citations

• Complete genome sequencing and genetic characterization of alkhumra hemorrhagic fever virus isolated from Najran, Saudi Arabia

  Madani, T. A., Azhar, E. I., Abuelzein, E. T. M. E., Kao, M., Al-Bar, H. M. S., Farraj, S. A., Masri, B. E., Al-Kaiedi, N. A., Shakil, S., Sohrab, S. S., Santalucia, J. & Ksiazek, T. G., Aug 2014, In: Intervirology. 57, 5, p. 300-310 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Whole Genome Sequencing
  • Saudi Arabia
  • Tick-Borne Encephalitis Viruses
  • Fever
  • Viruses
  7 Scopus citations

• Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection

  Flyak, A. I., Shen, X., Murin, C. D., Turner, H. L., David, J. A., Fusco, M. L., Lampley, R., Kose, N., Ilinykh, P. A., Kuzmina, N., Branchizio, A., King, H., Brown, L., Bryan, C., Davidson, E., Doranz, B. J., Slaughter, J. C., Sapparapu, G., Klages, C., Ksiazek, T. G. & 4 others, Saphire, E. O., Ward, A. B., Bukreyev, A. & Crowe, J. E., Jan 28 2016, In: Cell. 164, 3, p. 392-405 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Viruses
  • Neutralizing Antibodies
  • Antibody Formation
  • Infection
  99 Scopus citations

• Date palm sap linked to nipah virus outbreak in bangladesh, 2008

  Rahman, M. A., Hossain, M. J., Sultana, S., Homaira, N., Khan, S. U., Rahman, M., Gurley, E. S., Rollin, P. E., Lo, M. K., Comer, J. A., Lowe, L., Rota, P. A., Ksiazek, T. G., Kenah, E., Sharker, Y. & Luby, S. P., Jan 1 2012, In: Vector-Borne and Zoonotic Diseases. 12, 1, p. 65-72 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Phoeniceae
  • Nipah Virus
  • Chiroptera
  • Bangladesh
  • Disease Outbreaks
  112 Scopus citations

• Ebolavirus Chimerization for the Development of a Mouse Model for Screening of Bundibugyo-Specific Antibodies

  Ilinykh, P. A., Graber, J., Kuzmina, N. A., Huang, K., Ksiazek, T. G., Crowe, J. E. & Bukreyev, A., Nov 22 2018, In: Journal of Infectious Diseases. 218, p. S418-S422

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Viruses
  • Antibodies
  • Monoclonal Antibodies
  • Knockout Mice
  1 Scopus citations

• Exchange protein directly activated by cAMP modulates ebola virus uptake into vascular endothelial cells

  Drelich, A., Judy, B., He, X., Chang, Q., Yu, S., Li, X., Lu, F., Wakamiya, M., Popov, V., Zhou, J., Ksiazek, T. & Gong, B., Oct 16 2018, In: Viruses. 10, 10, 563.

  Research output: Contribution to journal › Article › peer-review

  • erythromycin propionate-N-acetylcysteinate
  • Ebolavirus
  • Endothelial Cells
  • Marburgvirus
  • Ebola Hemorrhagic Fever
  4 Scopus citations

• Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses

  Gong, B., Shelite, T., Mei, F. C., Ha, T., Hu, Y., Xu, G., Chang, Q., Wakamiya, M., Ksiazek, T. G., Boor, P. J., Bouyer, D. H., Popov, V. L., Chen, J., Walker, D. H. & Cheng, X., Nov 26 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 48, p. 19615-19620 6 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-(5-tert-butylisoxazol-3-yl)-2-((3-chlorophenyl)hydrazono)-3-oxopropionitrile
  • Spotted Fever Group Rickettsiosis
  • Bioterrorism
  • Bacterial Adhesion
  • Host-Pathogen Interactions
  48 Scopus citations

• Exchange protein directly activated by cAMP plays a critical role in regulation of vascular fibrinolysis

  He, X., Drelich, A., Yu, S., Chang, Q., Gong, D., Zhou, Y., Qu, Y., Yuan, Y., Su, Z., Qiu, Y., Tang, S. J., Gaitas, A., Ksiazek, T., Xu, Z., Zhou, J., Feng, Z., Wakamiya, M., Lu, F. & Gong, B., Mar 15 2019, In: Life Sciences. 221, p. 1-12 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Annexin A2
  • Endothelial cells
  • Fibrinolysis
  • Endothelial Cells
  • Blood Vessels
  2 Scopus citations

• Filoviruses: Marburg and ebola

  Ksiazek, T., Jun 1 2014, Viral Infections of Humans: Epidemiology and Control. Springer US, Vol. 9781489974488. p. 337-350 14 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Marburgvirus
  • Filoviridae
  • Ebolavirus
  • Disease Outbreaks
  • Viruses
  2 Scopus citations

• Growth characteristics of alkhumra hemorrhagic fever virus in mammalian cell lines

  Madani, T. A., Abuelzein, E. T. M. E., Azhar, E. I., Al-Bar, H. M. S., Hassan, A. M. & Ksiazek, T., Nov 1 2016, In: Vector-Borne and Zoonotic Diseases. 16, 11, p. 722-727 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Fever
  • Viruses
  • Cell Line
  • Growth
  • Canidae
  3 Scopus citations

• Identification of a new newcastle disease virus isolate from Indonesia represents an ancestral lineage of class II genotype XIII

  Forrester, N. L., Widen, S. G., Wood, T. G., Travassos Da Rosa, A. P., Ksiazek, T. G., Vasilakis, N. & Tesh, R. B., Aug 1 2013, In: Virus Genes. 47, 1, p. 168-172 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Newcastle disease virus
  • Indonesia
  • Genotype
  • Culicidae
  • Influenza in Birds
  9 Scopus citations

• Identification of Previously Unrecognized Viruses by Using Tissue Culture and Electron Microscopy

  Goldsmith, C. S., Ksiazek, T., Rollin, P. E., Comer, J. A., Nicholson, W. L., Peret, C. T., Erdman, D. D., Bellini, W. J., Bowen, M. D., Erickson, B. R., Nichol, S. T., Bhatnagar, J., McMullan, L. K., Paddock, C. D. & Zaki, S. R., 2012, In: Microscopy and Microanalysis. 18, S2, p. 174-175 2 p.

  Research output: Contribution to journal › Article › peer-review

• Increased talin–vinculin spatial proximities in livers in response to spotted fever group rickettsial and Ebola virus infections

  Liu, Y., Xiao, J., Zhang, B., Shelite, T. R., Su, Z., Chang, Q., Judy, B., Li, X., Drelich, A., Bei, J., Zhou, Y., Zheng, J., Jin, Y., Rossi, S. L., Tang, S. J., Wakamiya, M., Saito, T., Ksiazek, T., Kaphalia, B. & Gong, B., Aug 1 2020, In: Laboratory Investigation. 100, 8, p. 1030-1041 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Spotted Fever Group Rickettsiosis
  • Ebola Hemorrhagic Fever
  • Liver
  • Ebolavirus
  • Talin

• Infectious causes of encephalitis and meningoencephalitis in Thailand, 2003–2005

  LHCb collaboration, 2015, In: Emerging infectious diseases. 21, 2, p. 280-289 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Infectious Encephalitis
  • Meningoencephalitis
  • Thailand
  • Cerebrospinal Fluid
  • Orientia tsutsugamushi
  23 Scopus citations

• Mechanism of Human Antibody-Mediated Neutralization of Marburg Virus

  Flyak, A. I., Ilinykh, P. A., Murin, C. D., Garron, T., Shen, X., Fusco, M. L., Hashiguchi, T., Bornholdt, Z. A., Slaughter, J. C., Sapparapu, G., Klages, C., Ksiazek, T. G., Ward, A. B., Saphire, E. O., Bukreyev, A. & Crowe, J. E., Feb 26 2015, In: Cell. 160, 5, p. 893-903 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Marburgvirus
  • Viruses
  • Glycoproteins
  • Neutralizing Antibodies
  • Antibodies
  83 Scopus citations

• Propagation and titration of Alkhumra hemorrhagic fever virus in the brains of newborn Wistar rats

  Madani, T. A., Kao, M., Abuelzein, E. T. M. E., Azhar, E. I., Al-Bar, H. M. S., Abu-Araki, H., Bokhary, R. Y. & Ksiazek, T. G., Apr 1 2014, In: Journal of Virological Methods. 199, p. 39-45 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Wistar Rats
  • Fever
  • Viruses
  • Brain
  • RNA Viruses
  6 Scopus citations

• Reply to comment on: Successful propagation of Alkhumra (misnamed as Alkhurma) virus in C6/36 mosquito cells

  Madani, T. A., Kao, M., Azhar, E. I., Abuelzein, E. T. M. E., Al-Bar, H. M. S., Abu-Araki, H. & Ksiazek, T. G., Jun 1 2012, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 106, 6, p. 392-393 2 p.

  Research output: Contribution to journal › Letter › peer-review
  2 Scopus citations

• Seasonal Pulses of Marburg Virus Circulation in Juvenile Rousettus aegyptiacus Bats Coincide with Periods of Increased Risk of Human Infection

  Amman, B. R., Carroll, S. A., Reed, Z. D., Sealy, T. K., Balinandi, S., Swanepoel, R., Kemp, A., Erickson, B. R., Comer, J. A., Campbell, S., Cannon, D. L., Khristova, M. L., Atimnedi, P., Paddock, C. D., Kent Crockett, R. J., Flietstra, T. D., Warfield, K. L., Unfer, R., Katongole-Mbidde, E., Downing, R. & 6 others, Tappero, J. W., Zaki, S. R., Rollin, P. E., Ksiazek, T. G., Nichol, S. T. & Towner, J. S., Oct 2012, In: PLoS pathogens. 8, 10, e1002877.

  Research output: Contribution to journal › Article › peer-review

  • Marburgvirus
  • Chiroptera
  • Caves
  • Infection
  • Boidae
  184 Scopus citations

• Severe acute respiratory syndrome coronavirus 2 from patient with coronavirus disease, United States

  Harcourt, J., Tamin, A., Lu, X., Kamili, S., Sakthivel, S. K., Murray, J., Queen, K., Tao, Y., Paden, C. R., Zhang, J., Li, Y., Uehara, A., Wang, H., Goldsmith, C., Bullock, H. A., Wang, L., Whitaker, B., Lynch, B., Gautam, R., Schindewolf, C. & 14 others, Lokugamage, K. G., Scharton, D., Plante, J. A., Mirchandani, D., Widen, S. G., Narayanan, K., Makino, S., Ksiazek, T. G., Plante, K. S., Weaver, S. C., Lindstrom, S., Tong, S., Menachery, V. D. & Thornburg, N. J., Jun 1 2020, In: Emerging infectious diseases. 26, 6, p. 1266-1273 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Viruses
  • Vero Cells
  • Medical Countermeasures
  82 Scopus citations

• Successful propagation of Alkhumra (misnamed as Alkhurma) virus in C6/36 mosquito cells

  Madani, T. A., Kao, M., Azhar, E. I., Abuelzein, E. T. M. E., Al-Bar, H. M. S., Abu-Araki, H. & Ksiazek, T. G., Mar 1 2012, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 106, 3, p. 180-185 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Tick-Borne Encephalitis Viruses
  • Culicidae
  • Tick Bites
  • RNA
  • Viruses
  18 Scopus citations

• Superiority of the buffy coat over serum or plasma for the detection of Alkhumra virus RNA using real time RT-PCR

  Madani, T. A., Abuelzein, E. T. M. E., Azhar, E. I., Kao, M., Al-Bar, H. M. S., Abu-Araki, H. & Ksiazek, T. G., May 1 2012, In: Archives of virology. 157, 5, p. 819-823 5 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Viruses
  • Real-Time Polymerase Chain Reaction
  • Serum
  • Viruses
  • Viral RNA
  8 Scopus citations

• Susceptibility of tick cell lines to infection with alkhumra haemorrhagic fever virus

  Madani, T. A., Abuelzein, E. T. M. E., Bell-Sakyi, L., Azhar, E. I., Al-Bar, H. M. S., Abu-Araki, H., Hassan, A. M., Masri, B. E. & Ksiazek, T. G., Dec 2013, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 107, 12, p. 806-811 6 p., trt087.

  Research output: Contribution to journal › Article › peer-review

  • Ticks
  • Fever
  • Viruses
  • Cell Line
  • Infection
  3 Scopus citations

• Theoretical risk of genetic reassortment should not impede development of live, attenuated Rift Valley fever (RVF) vaccines commentary on the draft WHO RVF Target Product Profile

  Monath, T. P., Kortekaas, J., Watts, D. M., Christofferson, R. C., Desiree LaBeaud, A., Gowen, B., Peters, C. J., Smith, D. R., Swanepoel, R., Morrill, J. C., Ksiazek, T. G., Pittman, P. R., Bird, B. H. & Bettinger, G., Aug 7 2020, In: Vaccine: X. 5, 100060.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Rift Valley Fever
  • Rift Valley fever
  • Attenuated Vaccines
  • World Health Organization
  • live vaccines

• The Risk of Nosocomial Transmission of Rift Valley Fever

  Al-Hamdan, N. A., Panackal, A. A., Al Bassam, T. H., Alrabea, A., Al Hazmi, M., Al Mazroa, Y., Al Jefri, M., Khan, A. S. & Ksiazek, T. G., Dec 22 2015, In: PLoS neglected tropical diseases. 9, 12, e0004314.

  Research output: Contribution to journal › Article › peer-review

  • Rift Valley Fever
  • Viral Hemorrhagic Fevers
  • Health Personnel
  • Ebola Hemorrhagic Fever
  • Infection Control
  14 Scopus citations

• The Role of a National Biocontainment Laboratory in Emergencies

  Le Duc, J. W. & Ksiazek, T. G., Sep 1 2015, In: Health Security. 13, 5, p. 345-348 4 p.

  Research output: Contribution to journal › Review article › peer-review

  • public health
  • Public health
  • Emergencies
  • biosafety
  • applied research