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• Therapeutics for Dengue: Recommendations for Design and Conduct of Early-Phase Clinical Trials

  Simmons, C. P., Wolbers, M., Nguyen, M. N., Whitehorn, J., Shi, P. Y., Young, P., Petric, R., Nguyen, V. V. C., Farrar, J. & Wills, B., Sep 2012, In: PLoS neglected tropical diseases. 6, 9, e1752.

  Research output: Contribution to journal › Article › peer-review
  25 Scopus citations

• Therapeutics for Neglected Infectious Diseases: Progress and Challenge

  Shi, P. Y., Smith, P. W. & Diagana, T. T., Jan 8 2015, In: ACS Infectious Diseases. 1, 1, p. 76-78 3 p.

  Research output: Contribution to journal › Short survey › peer-review
  7 Scopus citations

• The search for nucleoside/nucleotide analog inhibitors of dengue virus

  Chen, Y. L., Yokokawa, F. & Shi, P. Y., Aug 10 2015, In: Antiviral research. 122, p. 12-19 8 p., 3670.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue Virus
  • Nucleosides
  • Antiviral Agents
  • Nucleotides
  • Sofosbuvir
  44 Scopus citations

• The stem region of premembrane protein plays an important role in the virus surface protein rearrangement during dengue maturation

  Zhang, Q., Hunke, C., Yau, Y. H., Seow, V., Lee, S., Tanner, L. B., Guan, X. L., Wenk, M. R., Fibriansah, G., Chew, P. L., Kukkaro, P., Biuković, G., Shi, P. Y., Shochat, S. G., Grüber, G. & Lok, S. M., Nov 23 2012, In: Journal of Biological Chemistry. 287, 48, p. 40525-40534 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Viruses
  • Dengue
  • Membrane Proteins
  • Exosomes
  • Dengue Virus
  32 Scopus citations

• The structural basis for serotype-specific neutralization of dengue virus by a human antibody

  Teoh, E. P., Kukkaro, P., Teo, E. W., Lim, A. P. C., Tan, T. T., Yip, A., Schul, W., Aung, M., Kostyuchenko, V. A., Leo, Y. S., Chan, S. H., Smith, K. G. C., Chan, A. H. Y., Zou, G., Ooi, E. E., Kemeny, D. M., Tan, G. K., Ng, J. K. W., Ng, M. L., Alonso, S. & 5 others, Fisher, D., Shi, P. Y., Hanson, B. J., Lok, S. M. & MacAry, P. A., Jun 20 2012, In: Science Translational Medicine. 4, 139, 139ra83.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Serogroup
  • Antibodies
  • Immunity
  • Cryoelectron Microscopy
  165 Scopus citations

• Treatment of human glioblastoma with a live attenuated Zika virus vaccine candidate

  Chen, Q., Wu, J., Ye, Q., Ma, F., Zhu, Q., Wu, Y., Shan, C., Xie, X., Li, D., Zhan, X., Li, C., Li, X. F., Qin, X., Zhao, T., Wu, H., Shi, P. Y., Man, J. & Qin, C. F., Sep 1 2018, In: mBio. 9, 5, e01683-18.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Glioblastoma
  • Vaccines
  • Glioma
  • Stem Cells
  32 Scopus citations

• Two distinct sets of NS2A molecules are responsible for dengue virus RNA synthesis and virion assembly

  Xie, X., Zou, J., Puttikhunt, C., Yuan, Z. & Shi, P. Y., 2015, In: Journal of virology. 89, 2, p. 1298-1313 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Dengue Virus
  • virion
  • Virion
  • RNA
  53 Scopus citations

• Type I interferon signals in macrophages and dendritic cells control dengue virus infection: Implications for a new mouse model to test dengue vaccines

  Züst, R., Toh, Y. X., Valdés, I., Cerny, D., Heinrich, J., Hermida, L., Marcos, E., Guillén, G., Kalinke, U., Shi, P. Y. & Fink, K., 2014, In: Journal of virology. 88, 13, p. 7276-7285 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Vaccines
  • Dengue virus
  • dendritic cells
  • dengue
  • Interferon Type I
  52 Scopus citations

• U18666A, an intra-cellular cholesterol transport inhibitor, inhibits dengue virus entry and replication

  Poh, M. K., Shui, G., Xie, X., Shi, P. Y., Wenk, M. R. & Gu, F., Jan 2012, In: Antiviral research. 93, 1, p. 191-198 8 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one
  • Anticholesteremic Agents
  • Virus Internalization
  • Dengue Virus
  • Virus Replication
  72 Scopus citations

• Understanding zika virus stability and developing a chimeric vaccine through functional analysis

  Xie, X., Yang, Y., Muruato, A. E., Zou, J., Shan, C., Nunes, B. T. D., Medeiros, D. B. A., Vasconcelos, P. F. C., Weaver, S. C., Rossi, S. L. & Shi, P. Y., Jan 1 2017, In: mBio. 8, 1, e02134-16.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Vaccines
  • Viruses
  • Hydrogen
  • Virion
  62 Scopus citations

• Unraveling a flavivirus enigma

  Shi, P. Y., Jan 1 2014, In: Science. 343, 6173, p. 849-850 2 p.

  Research output: Contribution to journal › Short survey › peer-review

  • Flavivirus
  • Proteins
  9 Scopus citations

• Using a virion assembly-defective dengue virus as a vaccine approach

  Shan, C., Xie, X., Zou, J., Züst, R., Zhang, B., Ambrose, R., Mackenzie, J., Fink, K. & Shi, P. Y., Nov 1 2018, In: Journal of virology. 92, 21, e01002.

  Research output: Contribution to journal › Article › peer-review

  • Defective Viruses
  • Dengue virus
  • Dengue Virus
  • virion
  • Virion
  10 Scopus citations

• Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease

  Richner, J. M., Jagger, B. W., Shan, C., Fontes, C. R., Dowd, K. A., Cao, B., Himansu, S., Caine, E. A., Nunes, B. T. D., Medeiros, D. B. A., Muruato, A. E., Foreman, B. M., Luo, H., Wang, T., Barrett, A. D., Weaver, S. C., Vasconcelos, P. F. C., Rossi, S. L., Ciaramella, G., Mysorekar, I. U. & 3 others, Pierson, T. C., Shi, P. Y. & Diamond, M. S., Jul 13 2017, In: Cell. 170, 2, p. 273-283.e12

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Viruses
  • Vaccines
  • Glycosylation
  • Fetus
  124 Scopus citations

• West Nile virus drug discovery

  Lim, S. P. & Shi, P. Y., Dec 3 2013, In: Viruses. 5, 12, p. 2977-3006 30 p.

  Research output: Contribution to journal › Review article › peer-review

  • West Nile virus
  • Drug Discovery
  • Antiviral Agents
  • Antibodies
  • Flaviviridae
  27 Scopus citations

• West Nile virus NS1 antagonizes interferon beta production by targeting RIG-I and MDA5

  Zhang, H. L., Ye, H. Q., Liu, S. Q., Deng, C. L., Li, X. D., Shi, P. Y. & Zhang, B., Sep 1 2017, In: Journal of virology. 91, 18, e02396-16.

  Research output: Contribution to journal › Article › peer-review

  • West Nile virus nonstructural protein 1
  • interferon-beta
  • West Nile virus
  • retinoic acid
  • Interferon-beta
  29 Scopus citations

• Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network

  Aliota, M. T., Bassit, L., Bradrick, S. S., Cox, B., Garcia-Blanco, M. A., Gavegnano, C., Friedrich, T. C., Golos, T. G., Griffin, D. E., Haddow, A. D., Kallas, E. G., Kitron, U., Lecuit, M., Magnani, D. M., Marrs, C., Mercer, N., McSweegan, E., Ng, L. F. P., O'Connor, D. H., Osorio, J. E. & 11 others, Ribeiro, G. S., Ricciardi, M., Rossi, S. L., Saade, G., Schinazi, R. F., Schott-Lerner, G. O., Shan, C., Shi, P. Y., Watkins, D. I., Vasilakis, N. & Weaver, S. C., Aug 2017, In: Antiviral research. 144, p. 223-246 24 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus Infection
  • Zika Virus
  • Viruses
  • Routine Diagnostic Tests
  • Antiviral Agents
  67 Scopus citations

• Zika virus has oncolytic activity against glioblastoma stem cells

  Zhu, Z., Gorman, M. J., McKenzie, L. D., Chai, J. N., Hubert, C. G., Prager, B. C., Fernandez, E., Richner, J. M., Zhang, R., Shan, C., Tycksen, E., Wang, X., Shi, P. Y., Diamond, M. S., Rich, J. N. & Chheda, M. G., 2017, In: Journal of Experimental Medicine. 214, 10, p. 2843-2857 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Glioblastoma
  • Stem Cells
  • Flavivirus
  • Oncolytic Virotherapy
  77 Scopus citations

• Zika virus infection elicits auto-antibodies to C1q

  Koma, T., Veljkovic, V., Anderson, D. E., Wang, L. F., Rossi, S. L., Shan, C., Shi, P. Y., Beasley, D. W., Bukreyeva, N., Smith, J. N., Hallam, S., Huang, C., Von Messling, V. & Paessler, S., Dec 1 2018, In: Scientific reports. 8, 1, 1882.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus Infection
  • Zika Virus
  • Antibodies
  • Complement C1q
  • Viral Structures
  10 Scopus citations

• Zika virus infects human Sertoli cells and modulates the integrity of the in vitro blood-testis barrier model

  Siemann, D. N., Strange, D. P., Maharaj, P. N., Shi, P. Y. & Verma, S., Nov 1 2017, In: Journal of virology. 91, 22, e00623-17.

  Research output: Contribution to journal › Article › peer-review

  • Zika virus
  • Blood-Testis Barrier
  • Zika Virus
  • Sertoli Cells
  • Sertoli cells
  46 Scopus citations

• Zika Virus Vaccine: Progress and Challenges

  Shan, C., Xie, X. & Shi, P. Y., Jul 11 2018, In: Cell Host and Microbe. 24, 1, p. 12-17 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus
  • Vaccines
  • Eye Abnormalities
  • Flavivirus
  • Explosive Agents
  36 Scopus citations