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• Activation of Human Peripheral Blood Eosinophils by Cytokines in a Comparative Time-Course Proteomic/Phosphoproteomic Study

  Soman, K. V., Stafford, S. J., Pazdrak, K., Wu, Z., Luo, X., White, W. I., Wiktorowicz, J. E., Calhoun, W. J. & Kurosky, A., Aug 4 2017, In: Journal of Proteome Research. 16, 8, p. 2663-2679 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics
  • Eosinophils
  • Blood
  • Chemical activation
  • Cytokines
  8 Scopus citations

• Alcoholic lung injury: Metabolic, biochemical and immunological aspects

  Kaphalia, L. & Calhoun, W. J., Oct 4 2013, In: Toxicology Letters. 222, 2, p. 171-179 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Lung Injury
  • Alcohols
  • Oxidative stress
  • Oxidative Stress
  • Alcoholism
  55 Scopus citations

• Aldose Reductase Inhibition Prevents Allergic Airway Remodeling through PI3K/AKT/GSK3β Pathway in Mice

  Yadav, U. C. S., Naura, A. S., Aguilera-Aguirre, L., Boldogh, I., Boulares, H. A., Calhoun, W. J., Ramana, K. V. & Srivastava, S. K., Feb 27 2013, In: PloS one. 8, 2, e57442.

  Research output: Contribution to journal › Article › peer-review

  • Aldehyde Reductase
  • phosphatidylinositol 3-kinase
  • Airway Remodeling
  • Phosphatidylinositol 3-Kinases
  • mice
  27 Scopus citations

• An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype

  Holguin, F., Comhair, S. A. A., Hazen, S. L., Powers, R. W., Khatri, S. S., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Teague, W. G., Chung, K. F., Erzurum, S. C. & Wenzel, S. E., Jan 15 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 2, p. 153-159 7 p.

  Research output: Contribution to journal › Article › peer-review

  • N,N-dimethylarginine
  • Age of Onset
  • Arginine
  • Asthma
  • Obesity
  97 Scopus citations

• Assessing and Evaluating Multidisciplinary Translational Teams: A Mixed Methods Approach

  Wooten, K. C., Rose, R. M., Ostir, G. V., Calhoun, W. J., Ameredes, B. T. & Brasier, A. R., 2014, In: Evaluation and the Health Professions. 37, 1, p. 33-49 17 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Benralizumab - A humanized mAb to IL-5Rα with enhanced antibody-dependent cell-mediated cytotoxicity - A novel approach for the treatment of asthma

  Ghazi, A., Trikha, A. & Calhoun, W. J., Jan 2012, In: Expert Opinion on Biological Therapy. 12, 1, p. 113-118 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • benralizumab
  • Cytotoxicity
  • Antibody-Dependent Cell Cytotoxicity
  • Interleukin-5
  • Asthma
  109 Scopus citations

• Biologic Therapy in Chronic Obstructive Pulmonary Disease

  Tripple, J., McCracken, J. & Calhoun, W., May 1 2017, In: Immunology and Allergy Clinics of North America. 37, 2, p. 345-355 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Biological Therapy
  • Chronic Obstructive Pulmonary Disease
  • Inflammation
  • Environmental Exposure
  • Biological Factors
  5 Scopus citations

• Characteristics of perimenstrual asthma and its relation to asthma severity and control: Data from the Severe Asthma Research Program

  Rao, C. K., Moore, C. G., Bleecker, E., Busse, W. W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S. C., Israel, E., Curran-Everett, D. & Wenzel, S. E., Apr 2013, In: Chest. 143, 4, p. 984-992 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Aspirin
  • National Heart, Lung, and Blood Institute (U.S.)
  • Demography
  • Patient Acceptance of Health Care
  51 Scopus citations

• Clinical burden and predictors of asthma exacerbations in patients on guideline-based steps 4-6 asthma therapy in the TENOR cohort

  Calhoun, W. J., Haselkorn, T., Mink, D. R., Miller, D. P., Dorenbaum, A. & Zeiger, R. S., Mar 2014, In: Journal of Allergy and Clinical Immunology: In Practice. 2, 2, p. 193-200.e3

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Guidelines
  • Odds Ratio
  • Quality of Life
  • Therapeutics
  30 Scopus citations

• Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: The BASALT randomized controlled trial

  Calhoun, W. J., Ameredes, B. T., King, T. S., Icitovic, N., Bleecker, E. R., Castro, M., Cherniack, R. M., Chinchilli, V. M., Craig, T., Denlinger, L., DiMango, E. A., Engle, L. L., Fahy, J. V., Grant, J. A., Israel, E., Jarjour, N., Kazani, S. D., Kraft, M., Kunselman, S. J., Lazarus, S. C. & 15 others, Lemanske, R. F., Lugogo, N., Martin, R. J., Meyers, D. A., Moore, W. C., Pascual, R., Peters, S. P., Ramsdell, J., Sorkness, C. A., Sutherland, E. R., Szefler, S. J., Wasserman, S. I., Walter, M. J., Wechsler, M. E. & Boushey, H. A., Sep 5 2012, In: JAMA - Journal of the American Medical Association. 308, 10, p. 987-997 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Adrenal Cortex Hormones
  • Asthma
  • Randomized Controlled Trials
  • Biomarkers
  • Physicians
  124 Scopus citations

• Conclusions and future directions

  Calhoun, W. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  1 Scopus citations

• Conclusions and future directions

  Calhoun, W. J. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Diagnosis and management of asthma in adults a review

  McCracken, J., Veeranki, S. P., Ameredes, B. & Calhoun, W., Jul 18 2017, In: JAMA - Journal of the American Medical Association. 318, 3, p. 279-290 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Asthma
  • Adrenal Cortex Hormones
  • Biological Factors
  • Airway Obstruction
  • reslizumab
  66 Scopus citations

• Ethanol metabolism, oxidative stress, and endoplasmic reticulum stress responses in the lungs of hepatic alcohol dehydrogenase deficient deer mice after chronic ethanol feeding

  Kaphalia, L., Boroumand, N., Hyunsu, J., Kaphalia, B. S. & Calhoun, W. J., Jun 1 2014, In: Toxicology and Applied Pharmacology. 277, 2, p. 109-117 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxidative stress
  • Peromyscus
  • Alcohol Dehydrogenase
  • Metabolism
  • Endoplasmic Reticulum Stress
  18 Scopus citations

• Genome-wide association study identifies T_H1 pathway genes associated with lung function in asthmatic patients

  Li, X., Hawkins, G. A., Ampleford, E. J., Moore, W. C., Li, H., Hastie, A. T., Howard, T. D., Boushey, H. A., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Israel, E., Lemanske, R. F., Szefler, S. J., Wasserman, S. I., Wenzel, S. E., Peters, S. P., Meyers, D. A. & Bleecker, E. R., Aug 2013, In: Journal of Allergy and Clinical Immunology. 132, 2, p. 313-320.e15

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Asthma
  • Lung
  • Genes
  • Single Nucleotide Polymorphism
  67 Scopus citations

• Heterogeneity of asthma in society

  Divekar, R. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Vitamin D
  • Asthma
  • Immunologic Factors
  • Animals
  • Obesity
  4 Scopus citations

• Heterogeneity of asthma in society

  Divekar, R. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Vitamin D
  • Asthma
  • Immunologic Factors
  • Animals
  • Obesity

• Heterogeneity of response to therapy

  Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Asthma
  • Physiology
  • Restoration
  • Therapeutics
  • History

• Heterogeneity of response to therapy

  Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Asthma
  • Physiology
  • Restoration
  • Therapeutics
  • History

• HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma

  Zein, J., Gaston, B., Bazeley, P., DeBoer, M. D., Igo, R. P., Bleecker, E. R., Meyers, D., Comhair, S., Marozkina, N. V., Cotton, C., Patel, M., Alyamani, M., Xu, W., Busse, W. W., Calhoun, W. J., Ortega, V., Hawkins, G. A., Castro, M., Chung, K. F., Fahy, J. V. & 12 others, Fitzpatrick, A. M., Israel, E., Jarjour, N. N., Levy, B., Mauger, D. T., Moore, W. C., Noel, P., Peters, S. P., Teague, W. G., Wenzel, S. E., Erzurum, S. C. & Sharifi, N., Jan 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2187-2193 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glucocorticoids
  • Asthma
  • Genotype
  • Androgens
  • 3-Hydroxysteroid Dehydrogenases
  3 Scopus citations

• Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients

  Silkoff, P. E., Laviolette, M., Singh, D., FitzGerald, J. M., Kelsen, S., Backer, V., Porsbjerg, C. M., Girodet, P. O., Berger, P., Kline, J. N., Chupp, G., Susulic, V. S., Barnathan, E. S., Baribaud, F., Loza, M. J., Strambu, I., Lam, S., Eich, A., Ludwig-Sengpiel, A., Leigh, R. & 4 others, Dransfield, M., Calhoun, W., Hussaini, A. & Chanez, P., Sep 2017, In: Journal of Allergy and Clinical Immunology. 140, 3, p. 710-719 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Eosinophils
  • Biomarkers
  • Nitric Oxide
  • Inflammation
  27 Scopus citations

• Introduction to asthma and phenotyping

  Pillai, R. A. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Asthma
  • Phenotype
  • Airway Obstruction
  • Patient Care
  • Inflammation

• Introduction to asthma and phenotyping

  Pillai, R. A. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Asthma
  • Phenotype
  • Airway Obstruction
  • Patient Care
  • Inflammation
  5 Scopus citations

• Key observations from the NHLBI Asthma Clinical Research Network

  Szefler, S. J., Chinchilli, V. M., Israel, E., Denlinger, L. C., Lemanske, R. F., Calhoun, W. & Peters, S. P., May 2012, In: Thorax. 67, 5, p. 450-455 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • National Heart, Lung, and Blood Institute (U.S.)
  • Asthma
  • Tiotropium Bromide
  • Leukotriene Antagonists
  • Clinical Trials
  10 Scopus citations

• Management of Acute Asthma in Adults in 2020

  Zaidan, M. F., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 563-564 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  1 Scopus citations

• National estimates of 30-day readmissions among children hospitalized for asthma in the United States

  Veeranki, S., Ohabughiro, M. U., Moran, J., Mehta, H. B., Ameredes, B. T., Kuo, Y. F. & Calhoun, W. J., Jul 3 2018, In: Journal of Asthma. 55, 7, p. 695-704 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Hospitalized Child
  • Patient Readmission
  • Asthma
  • Hospital Bed Capacity
  • Length of Stay
  7 Scopus citations

• Obesity's effect on asthma extends to diagnostic criteria

  Lugogo, N., Green, C. L., Agada, N., Zhang, S., Meghdadpour, S., Zhou, R., Yang, S., Anstrom, K. J., Israel, E., Martin, R., Lemanske, R. F., Boushey, H., Lazarus, S. C., Wasserman, S. I., Castro, M., Calhoun, W., Peters, S. P., DiMango, E., Chinchilli, V., Kunselman, S. & 3 others, King, T. S., Icitovic, N. & Kraft, M., Mar 2018, In: Journal of Allergy and Clinical Immunology. 141, 3, p. 1096-1104 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Eosinophils
  • Asthma
  • Obesity
  • Biomarkers
  • Sputum
  15 Scopus citations

• Outpatient Management of Chronic Asthma in 2020

  Tripple, J. W., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 561-562 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  3 Scopus citations

• P2X₇-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy

  Denlinger, L. C., Manthei, D. M., Seibold, M. A., Ahn, K., Bleecker, E., Boushey, H. A., Calhoun, W. J., Castro, M., Chinchili, V. M., Fahy, J. V., Hawkins, G. A., Icitovic, N., Israel, E., Jarjour, N. N., King, T., Kraft, M., Lazarus, S. C., Lehman, E., Martin, R. J., Meyers, D. A. & 8 others, Peters, S. P., Sheerar, D., Shi, L., Sutherland, E. R., Szefler, S. J., Wechsler, M. E., Sorkness, C. A. & Lemanske, R. F., Jan 1 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 1, p. 28-33 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Adrenal Cortex Hormones
  • Purinergic P2X7 Receptors
  • Therapeutics
  • Confidence Intervals
  13 Scopus citations

• Physician-, biomarker-, and symptombased djustment of inhaled corticosteroids for asthma had similar effects

  Calhoun, W. J., Jan 24 2013, In: Annals of internal medicine. 158, 2, p. JC6

  Research output: Contribution to journal › Comment/debate › peer-review

• Post-transplant native pneumonectomy for interstitial fibrosis and small cell lung cancer

  Li, R. T., Zahedi, S., Trieu, J., Lea, A. S., Calhoun, W. J., Duarte, A. G., Zhao, J. & Okereke, I. C., Dec 1 2017, In: Journal of Thoracic Disease. 9, 12, p. E1096-E1099

  Research output: Contribution to journal › Article › peer-review

  • Pneumonectomy
  • Lung Transplantation
  • Small Cell Lung Carcinoma
  • Lung Neoplasms
  • Fibrosis

• Predictors of response to tiotropium versus salmeterol in asthmatic adults

  Peters, S. P., Bleecker, E. R., Kunselman, S. J., Icitovic, N., Moore, W. C., Pascual, R., Ameredes, B. T., Boushey, H. A., Calhoun, W. J., Castro, M., Cherniack, R. M., Craig, T., Denlinger, L. C., Engle, L. L., Dimango, E. A., Israel, E., Kraft, M., Lazarus, S. C., Lemanske, R. F., Lugogo, N. & 10 others, Martin, R. J., Meyers, D. A., Ramsdell, J., Sorkness, C. A., Sutherland, E. R., Wasserman, S. I., Walter, M. J., Wechsler, M. E., Chinchilli, V. M. & Szefler, S. J., Nov 2013, In: Journal of Allergy and Clinical Immunology. 132, 5, p. 1068-1074.e1

  Research output: Contribution to journal › Article › peer-review

  • Tiotropium Bromide
  • Salmeterol Xinafoate
  • Asthma
  • Albuterol
  • Vital Capacity
  86 Scopus citations

• Race is associated with differences in airway inflammation in patients with asthma

  Nyenhuis, S. M., Krishnan, J. A., Berry, A., Calhoun, W. J., Chinchilli, V. M., Engle, L., Grossman, N., Holguin, F., Israel, E., Kittles, R. A., Kraft, M., Lazarus, S. C., Lehman, E. B., Mauger, D. T., Moy, J. N., Peters, S. P., Phipatanakul, W., Smith, L. J., Sumino, K., Szefler, S. J. & 4 others, Wechsler, M. E., Wenzel, S., White, S. R. & Ackerman, S. J., Jul 2017, In: Journal of Allergy and Clinical Immunology. 140, 1, p. 257-265.e11

  Research output: Contribution to journal › Article › peer-review

  • African Americans
  • European Continental Ancestry Group
  • Asthma
  • Inflammation
  • Sputum
  19 Scopus citations

• Severe asthma: Lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program

  Jarjour, N. N., Erzurum, S. C., Bleecker, E. R., Calhoun, W. J., Castro, M., Comhair, S. A. A., Chung, K. F., Curran-Everett, D., Dweik, R. A., Fain, S. B., Fitzpatrick, A. M., Gaston, B. M., Israel, E., Hastie, A., Hoffman, E. A., Holguin, F., Levy, B. D., Meyers, D. A., Moore, W. C., Peters, S. P. & 4 others, Sorkness, R. L., Teague, W. G., Wenzel, S. E. & Busse, W. W., Feb 15 2012, In: American Journal of Respiratory and Critical Care Medicine. 185, 4, p. 356-362 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • National Heart, Lung, and Blood Institute (U.S.)
  • Asthma
  • Bronchoscopy
  169 Scopus citations

• Sleep quality and asthma control and quality of life in non-severe and severe asthma

  Luyster, F. S., Teodorescu, M., Bleecker, E., Busse, W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S., Israel, E., Strollo, P. J. & Wenzel, S. E., Dec 2012, In: Sleep and Breathing. 16, 4, p. 1129-1137 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Quality Control
  • Sleep
  • Asthma
  • Gastroesophageal Reflux
  • Quality of Life
  54 Scopus citations

• Strategies for molecular classification of asthma using bipartite network analysis of cytokine expression

  Pillai, R. R., Divekar, R., Brasier, A., Bhavnani, S. & Calhoun, W. J., Oct 2012, In: Current Allergy and Asthma Reports. 12, 5, p. 388-395 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Cytokines
  • Health Care Costs
  • Signs and Symptoms
  • Data Analysis
  15 Scopus citations

• Strategies for Tailoring Asthma Treatment in Adults-Reply

  Calhoun, W. J., Boushey, H. A. & Ameredes, B. T., Jan 9 2013, In: JAMA - Journal of the American Medical Association. 309, 2, p. 136-137 2 p.

  Research output: Contribution to journal › Letter › peer-review

• Symptom-based controller therapy: A new paradigm for asthma management

  Divekar, R., Ameredes, B. T. & Calhoun, W. J., Oct 2013, In: Current Allergy and Asthma Reports. 13, 5, p. 427-433 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Adrenal Cortex Hormones
  • Guidelines
  • Nebulizers and Vaporizers
  • Therapeutics
  1 Scopus citations

• The CTSA as an Exemplar Framework for Developing Multidisciplinary Translational Teams

  Calhoun, W. J., Wooten, K., Bhavnani, S., Anderson, K. E., Freeman, J. & Brasier, A. R., Feb 2013, In: Clinical and translational science. 6, 1, p. 60-71 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Education
  • Industry
  • Data Analysis
  • Technology
  • Therapeutics
  20 Scopus citations

• The spectrum of asthma: an introduction.

  Calhoun, W. J., 2014, In: Advances in experimental medicine and biology. 795, p. 1-4 4 p.

  Research output: Contribution to journal › Editorial › peer-review

• Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data

  Wu, W., Bleecker, E., Moore, W., Busse, W. W., Castro, M., Chung, K. F., Calhoun, W. J., Erzurum, S., Gaston, B., Israel, E., Curran-Everett, D. & Wenzel, S. E., May 2014, In: Journal of Allergy and Clinical Immunology. 133, 5, p. 1280-1288 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Lung
  • Unsupervised Machine Learning
  • Cluster Analysis
  • Asthma and Nasal Polyps
  149 Scopus citations