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• Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts

  Wold, E. A., Chen, J., Cunningham, K. A. & Zhou, J., Oct 1 2019, In: Journal of medicinal chemistry. 62, 1, p. 88-127 40 p.

  Research output: Contribution to journal › Article › peer-review

  • G-Protein-Coupled Receptors
  • Drug Discovery
  • Pharmaceutical Chemistry
  • Drug Delivery Systems
  • Clinical Trials
  31 Scopus citations

• Altered anterior cingulate cortex to hippocampus effective connectivity in response to drug cues in men with cocaine use disorder

  Ma, L., Steinberg, J. L., Cunningham, K. A., Bjork, J. M., Lane, S. D., Schmitz, J. M., Burroughs, T., Narayana, P. A., Kosten, T. R., Bechara, A. & Moeller, F. G., Jan 30 2018, In: Psychiatry Research - Neuroimaging. 271, p. 59-66 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Gyrus Cinguli
  • Cocaine
  • Cues
  • Hippocampus
  • Attentional Bias
  5 Scopus citations

• Anterior insula activity regulates the associated behaviors of high fat food binge intake and cue reactivity in male rats

  Price, A. E., Stutz, S. J., Hommel, J. D., Anastasio, N. C. & Cunningham, K. A., Feb 1 2019, In: Appetite. 133, p. 231-239 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cues
  • Eating
  • Fats
  • Bulimia
  • Food
  3 Scopus citations

• A protocol for measuring cue reactivity in a rat model of cocaine use disorder

  Dimet, A. L., Cisneros, I. E., Fox, R. G., Stutz, S. J., Anastasio, N. C., Cunningham, K. A. & Dineley, K. T., Jun 20 2018, In: Journal of Visualized Experiments. 2018, 136, e55864.

  Research output: Contribution to journal › Article › peer-review

  • Rats
  • Cocaine
  • Cues
  • Drug therapy
  • Self Administration
  4 Scopus citations

• Biophysical validation of serotonin 5-HT_2A and 5-HT_2C receptor interaction

  Felsing, D. E., Anastasio, N. C., Miszkiel, J. M., Gilbertson, S. R., Allen, J. A. & Cunningham, K. A., Aug 2018, In: PloS one. 13, 8, e0203137.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Receptor, Serotonin, 5-HT2A
  • serotonin
  • Serotonin
  • receptors
  11 Scopus citations

• Chronic poly-drug administration damages adult mouse brain neural stem cells

  McGrath, E. L., Schlagal, C. R., Cortez, I., Dunn, T. J., Gao, J., Fox, R. G., Stutz, S. J., Kuo, Y. F., Hommel, J. D., Dineley, K. T., Cunningham, K. A., Kaphalia, B. S. & Wu, P., Nov 15 2019, In: Brain Research. 1723, 146425.

  Research output: Contribution to journal › Article › peer-review

  • Neural Stem Cells
  • Brain Stem
  • Cocaine
  • Ethanol
  • Pharmaceutical Preparations

• Cingulo-hippocampal effective connectivity positively correlates with drug-cue attentional bias in opioid use disorder

  Ma, L., Steinberg, J. L., Bjork, J. M., Taylor, B. A., Arias, A. J., Terplan, M., Anastasio, N. C., Zuniga, E. A., Lennon, M., Cunningham, K. A. & Moeller, F. G., Dec 30 2019, In: Psychiatry Research - Neuroimaging. 294, 110977.

  Research output: Contribution to journal › Article › peer-review

  • Attentional Bias
  • Opioid Analgesics
  • Cues
  • Pharmaceutical Preparations
  • Gyrus Cinguli
  2 Scopus citations

• Cocaine evokes a profile of oxidative stress and impacts innate antiviral response pathways in astrocytes

  Cisneros, I. E., Erdenizmenli, M., Cunningham, K. A., Paessler, S. & Dineley, K. T., Jun 2018, In: Neuropharmacology. 135, p. 431-443 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Cocaine
  • Astrocytes
  • Antiviral Agents
  • Oxidative Stress
  • Zika Virus
  7 Scopus citations

• Coevolution of Residues Provides Evidence of a Functional Heterodimer of 5-HT_2AR and 5-HT_2CR Involving Both Intracellular and Extracellular Domains

  Fongang, B., Cunningham, K. A., Rowicka, M. & Kudlicki, A., Aug 1 2019, In: Neuroscience. 412, p. 48-59 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Substance-Related Disorders
  • Single Nucleotide Polymorphism
  • serotonin 5 receptor
  • Proteins
  • Appetite
  1 Scopus citations

• Convergent neural connectivity in motor impulsivity and high-fat food binge-like eating in male Sprague-Dawley rats

  Anastasio, N. C., Stutz, S. J., Price, A. E., Davis-Reyes, B. D., Sholler, D. J., Ferguson, S. M., Neumaier, J. F., Moeller, F. G., Hommel, J. D. & Cunningham, K. A., Sep 1 2019, In: Neuropsychopharmacology. 44, 10, p. 1752-1761 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Bulimia
  • Impulsive Behavior
  • Sprague Dawley Rats
  • Fats
  • Food
  7 Scopus citations

• Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT _2C Receptor

  Wild, C. T., Miszkiel, J. M., Wold, E. A., Soto, C. A., Ding, C., Hartley, R. M., White, M. A., Anastasio, N. C., Cunningham, K. A. & Zhou, J., Oct 1 2019, In: Journal of medicinal chemistry. 62, 1, p. 288-305 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Serotonin
  • 1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta(b)(1,4)diazepino(6,7,1hj)indole
  • Cocaine
  • Allosteric Site
  13 Scopus citations

• Discovery of 4-Phenylpiperidine-2-Carboxamide Analogues as Serotonin 5-HT_2CReceptor-Positive Allosteric Modulators with Enhanced Drug-like Properties

  Wold, E. A., Garcia, E. J., Wild, C. T., Miszkiel, J. M., Soto, C. A., Chen, J., Pazdrak, K., Fox, R. G., Anastasio, N. C., Cunningham, K. A. & Zhou, J., Jul 23 2020, In: Journal of medicinal chemistry. 63, 14, p. 7529-7544 16 p.

  Research output: Contribution to journal › Article › peer-review

  • 4-phenylpiperidine
  • Receptor, Serotonin, 5-HT2C
  • Serotonin
  • Pharmaceutical Preparations
  • Serotonin 5-HT2 Receptor Agonists
  2 Scopus citations

• Discovery of Potent and Brain-Penetrant GPR52 Agonist that Suppresses Psychostimulant Behavior

  Wang, P., Felsing, D., Chen, H., Stutz, S. J., Murphy, R., Cunningham, K., Allen, J. & Zhou, J., Nov 25 2020, In: Journal of Medicinal Chemistry. 63, 22, p. 13951 13972 p.

  Research output: Contribution to journal › Article › peer-review

  • G-Protein-Coupled Receptors
  • Brain
  • Proof of Concept Study
  • Structure-Activity Relationship
  • Central Nervous System Diseases

• Editorial: Contemporary Perspective on 5-HT_2C Receptor Function and Its Pharmacological Targeting

  De Deurwaerdère, P., Chagraoui, A. & Cunningham, K. A., Nov 23 2020, In: Frontiers in Pharmacology. 11, 606414.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• Editors' Favorites of 2017

  Lindsley, C. W., Cunningham, K. A., Hooker, J. M. & Andrews, A. M., Jan 17 2018, In: ACS chemical neuroscience. 9, 1, p. 1-4 4 p.

  Research output: Contribution to journal › Review article › peer-review
  1 Scopus citations

• Effects of escitalopram on attentional bias to cocaine-related stimuli and inhibitory control in cocaine-dependent subjects

  Liu, S., Lane, S. D., Schmitz, J. M., Cunningham, K. A., John, V. P. & Moeller, F. G., Sep 1 2013, In: Journal of Psychopharmacology. 27, 9, p. 801-807 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Attentional Bias
  • Citalopram
  • Cocaine
  • Cues
  • Short-Term Memory
  10 Scopus citations

• Elevated expression of serotonin 5-HT_2A receptors in the rat ventral tegmental area enhances vulnerability to the behavioral effects of cocaine

  Herin, D. V., Bubar, M. J., Seitz, P. K., Thomas, M. L., Hillman, G. R., Tarasenko, Y. I., Wu, P. & Cunningham, K. A., May 17 2013, In: Frontiers in Psychiatry. 4, FEB, Article 2.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2A
  • Ventral Tegmental Area
  • Cocaine
  • Locomotion
  • Parvovirus
  10 Scopus citations

• Endogenous Serotonin 5-HT_2A and 5-HT_2C Receptors Associate in the Medial Prefrontal Cortex

  Price, A. E., Sholler, D. J., Stutz, S. J., Anastasio, N. C. & Cunningham, K. A., Jul 17 2019, In: ACS chemical neuroscience. 10, 7, p. 3241-3248 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Receptor, Serotonin, 5-HT2A
  • Prefrontal Cortex
  • Serotonin
  • Rats
  7 Scopus citations

• Enhanced leptin sensitivity, reduced adiposity, and improved glucose homeostasis in mice lacking exchange protein directly activated by cyclic AMP Isoform 1

  Yan, J., Mei, F. C., Cheng, H., Lao, D. H., Hu, Y., Wei, J., Patrikeev, I., Hao, D., Stutz, S. J., Dineley, K. T., Motamedi, M., Hommel, J. D., Cunningham, K. A., Chen, J. & Cheng, X., Mar 2013, In: Molecular and cellular biology. 33, 5, p. 918-926 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Adiposity
  • Leptin
  • Cyclic AMP
  • Protein Isoforms
  • Homeostasis
  59 Scopus citations

• Exploration of synthetic approaches and pharmacological evaluation of PNU-69176E and its stereoisomer as 5-HT_2C receptor allosteric modulators

  Ding, C., Bremer, N. M., Smith, T. D., Seitz, P. K., Anastasio, N. C., Cunningham, K. A. & Zhou, J., Jul 18 2012, In: ACS chemical neuroscience. 3, 7, p. 538-545 8 p.

  Research output: Contribution to journal › Article › peer-review

  • L-threo-alpha-D-galacto-octopyranoside methyl-7-chloro-6,7,8-trideoxy-6-(((4-undecyl-2-piperidinyl)carbonyl)amino)-1-thiomonohydrochloride (2S-cis)
  • Receptor, Serotonin, 5-HT2C
  • Stereoisomerism
  • Modulators
  • Serotonin
  21 Scopus citations

• Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats

  Ezeomah, C., Cunningham, K. A., Stutz, S. J., Fox, R. G., Bukreyeva, N., Dineley, K. T., Paessler, S. & Cisneros, I. E., Jul 2020, In: Brain, Behavior, and Immunity. 87, p. 725-738 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Self Administration
  • Fentanyl
  • Interferons
  • Sprague Dawley Rats
  • Brain
  1 Scopus citations

• Forced abstinence from cocaine self-administration is associated with DNA methylation changes in myelin genes in the corpus callosum: A preliminary study

  Nielsen, D. A., Huang, W., Hamon, S. C., Maili, L., Witkin, B. M., Fox, R. G., Cunningham, K. A. & Moeller, F. G., 2012, In: Frontiers in Psychiatry. 3, JUN, Article 60.

  Research output: Contribution to journal › Article › peer-review

  • Self Administration
  • Corpus Callosum
  • Myelin Sheath
  • DNA Methylation
  • Cocaine
  27 Scopus citations

• Frontiers of biomolecular exploration in brain disorders

  Nilsson, C. L. & Cunningham, K. A., Jan 2014, In: Neuropsychopharmacology. 39, 1, p. 1-4 4 p.

  Research output: Contribution to journal › Review article › peer-review

• Functional status of the serotonin 5-HT 2C receptor (5-HT 2C R) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependence

  Anastasio, N. C., Stutz, S. J., Fox, R. G., Sears, R. M., Emeson, R. B., Dileone, R. J., O'Neil, R. T., Fink, L. H., Li, D., Green, T. A., Gerard Moeller, F. & Cunningham, K. A., Jan 2014, In: Neuropsychopharmacology. 39, 2, p. 360-372 13 p.

  Research output: Contribution to journal › Article › peer-review

  • serotonin 5 receptor
  • Cocaine-Related Disorders
  • Drive
  • Serotonin
  • Phenotype
  49 Scopus citations

• Increased intra-individual reaction time variability in cocaine-dependent subjects: Role of cocaine-related cues

  Liu, S., Lane, S. D., Schmitz, J. M., Green, C. E., Cunningham, K. A. & Moeller, F. G., Feb 2012, In: Addictive Behaviors. 37, 2, p. 193-197 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Cocaine
  • Reaction Time
  • Cues
  • Stroop Test
  • Electronic Data Processing
  15 Scopus citations

• Influence of methamphetamine on genital herpes simplex virus type 2 infection in a mouse model

  Valencia, F., Bubar, M. J., Milligan, G., Cunningham, K. A. & Bourne, N., Sep 2012, In: Sexually Transmitted Diseases. 39, 9, p. 720-725 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Herpes Genitalis
  • Methamphetamine
  • Herpes Simplex
  • Cytokines
  • Sexually Transmitted Diseases
  10 Scopus citations

• Inherent Motor Impulsivity Associates with Specific Gene Targets in the Rat Medial Prefrontal Cortex

  Sholler, D. J., Merritt, C. R., Davis-Reyes, B. D., Golovko, G., Anastasio, N. C. & Cunningham, K. A., May 21 2020, In: Neuroscience. 435, p. 161-173 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Impulsive Behavior
  • Prefrontal Cortex
  • Genes
  • Calcium Channels
  • leucyl-cystinyl aminopeptidase
  1 Scopus citations

• Innovative Therapeutic Intervention for Opioid Use Disorder

  Moeller, F. G. & Cunningham, K. A., Jan 1 2018, In: Neuropsychopharmacology. 43, 1, p. 220-221 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  5 Scopus citations

• In vivo and in vitro analyses of novel peptidomimetic disruptors for the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog (PTEN)

  Soto, C., Du, H. C., Fox, R., Yang, T., Hooson, J., Anastasio, N. C., Gilbertson, S. R., Cunningham, K. A., Cunningham, K. A. & Gilbertson, S. R., 2019, In: Frontiers in Pharmacology. 10, JULY, 907.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Receptor, Serotonin, 5-HT2C
  • Peptidomimetics
  • Tensins
  • Phosphoric Monoester Hydrolases
  • In Vitro Techniques
  3 Scopus citations

• Leave the Ordinary Elsewhere: Novel Serotonin Mechanisms to Address 21st Century Public Health Challenges

  Sholler, D. J. & Cunningham, K. A., Jul 17 2019, In: ACS chemical neuroscience. 10, 7, p. 3045-3046 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• Methylation Patterns of the HTR2A Associate With Relapse-Related Behaviors in Cocaine-Dependent Participants

  Land, M. A., Ramesh, D., Miller, A. L., Pyles, R. B., Cunningham, K. A., Moeller, F. G. & Anastasio, N. C., Jun 10 2020, In: Frontiers in Psychiatry. 11, 532.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cocaine
  • Methylation
  • Recurrence
  • Cues
  • Impulsive Behavior

• Multi-well plate immunoassays for measuring signaling protein activations/deactivations and membrane vs. intracellular receptor levels

  Watson, C. S., Jeng, Y. J., Bulayeva, N. N., Finnerty, C. C., Koong, L. Y., Zivadinovic, D., Alyea, R. A., Midoro-Horiuti, T., Goldblum, R. M., Anastasio, N. C., Cunningham, K. A., Seitz, P. K. & Smith, T. D., 2014, In: Methods in Molecular Biology. 1204, p. 123-133 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Immunoassay
  • Membranes
  • Neurotransmitter Agents
  • Proteins
  • Antigens
  2 Scopus citations

• Novel Bivalent 5-HT _2A Receptor Antagonists Exhibit High Affinity and Potency in Vitro and Efficacy in Vivo

  Soto, C. A., Shashack, M. J., Fox, R. G., Bubar, M. J., Rice, K. C., Watson, C. S., Cunningham, K. A., Gilbertson, S. R. & Anastasio, N. C., Mar 21 2018, In: ACS chemical neuroscience. 9, 3, p. 514-521 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2A
  • Serotonin
  • In Vitro Techniques
  • volinanserin
  • Ligands
  8 Scopus citations

• Peptide inhibitors disrupt the serotonin 5-HT_2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior

  Anastasio, N. C., Gilbertson, S. R., Bubar, M. J., Agarkov, A., Stutz, S. J., Jeng, Y., Bremer, N. M., Smith, T. D., Fox, R. G., Swinford, S. E., Seitz, P. K., Charendoff, M. N., Craft, J. W., Laezza, F. M., Watson, C. S., Briggs, J. M. & Cunningham, K. A., Jan 23 2013, In: Journal of Neuroscience. 33, 4, p. 1615-1630 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Tensins
  • Phosphoric Monoester Hydrolases
  • Peptides
  • Serotonin
  27 Scopus citations

• Positive-allosteric modulation of the 5-HT_2C receptor: implications for neuropsychopharmacology and neurotherapeutics

  Zhou, J. & Cunningham, K. A., Jan 1 2019, In: Neuropsychopharmacology. 44, 1, p. 230-231 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  6 Scopus citations

• PPARγ agonism attenuates cocaine cue reactivity

  Miller, W. R., Fox, R. G., Stutz, S. J., Lane, S. D., Denner, L., Cunningham, K. A. & Dineley, K. T., Jan 2018, In: Addiction Biology. 23, 1, p. 55-68 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Peroxisome Proliferator-Activated Receptors
  • Cocaine
  • Cues
  • 2-chloro-5-nitrobenzanilide
  • Craving
  12 Scopus citations

• Protein Co-Evolution Strategies Detect Predicted Functional Interaction Between the Serotonin 5-HT2A and 5-HT2C Receptors

  Fongang, B., Cunningham, K. A., Rowicka, M. & Kudlicki, A., Jan 6 2019, In: Unknown Journal.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • substance abuse
  • coevolution
  • serotonin
  • Serotonin

• Quantitative changes in intracellular calcium and extracellular-regulated kinase activation measured in parallel in CHO cells stably expressing serotonin (5-HT) 5-HT _2A or 5-HT _2C receptors

  Seitz, P. K., Bremer, N. M., McGinnis, A. G., Cunningham, K. A. & Watson, C. S., Mar 7 2012, In: BMC Neuroscience. 13, 1, 25.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • CHO Cells
  • Serotonin
  • Phosphotransferases
  • Calcium
  19 Scopus citations

• Serotonin2C receptors in the ventral pallidum regulate motor function in rats

  Graves, S. M., Viskniskki, A. A., Cunningham, K. A. & Celeste Napier, T., Aug 7 2013, In: NeuroReport. 24, 11, p. 605-608 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Basal Forebrain
  • Receptor, Serotonin, 5-HT2C
  • 6-chloro-2-(1-piperazinyl)pyrazine
  • Serotonin 5-HT2 Receptor Agonists
  • Serotonergic Neurons
  6 Scopus citations

• Serotonin 5-HT_2C receptor activation suppresses binge intake and the reinforcing and motivational properties of high-fat food

  Price, A. E., Anastasio, N. C., Stutz, S. J., Hommel, J. D. & Cunningham, K. A., Jul 27 2018, In: Frontiers in Pharmacology. 9, JUL, 821.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • 1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta(b)(1,4)diazepino(6,7,1hj)indole
  • Binge-Eating Disorder
  • Fats
  • Food
  10 Scopus citations

• Serotonin 5-HT_2C Receptor Cys23Ser Single Nucleotide Polymorphism Associates with Receptor Function and Localization In Vitro

  Land, M. A., Chapman, H. L., Davis-Reyes, B. D., Felsing, D. E., Allen, J. A., Moeller, F. G., Elferink, L. A., Cunningham, K. A. & Anastasio, N. C., Dec 1 2019, In: Scientific reports. 9, 1, 16737.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Receptor, Serotonin, 5-HT2C
  • Single Nucleotide Polymorphism
  • In Vitro Techniques
  • Alleles
  • Pharmacology
  1 Scopus citations

• Serotonin at the nexus of impulsivity and cue reactivity in cocaine addiction

  Cunningham, K. A. & Anastasio, N. C., 2014, In: Neuropharmacology. 76, PART B, p. 460-478 19 p.

  Research output: Contribution to journal › Review article › peer-review

  • Nexus
  • Cocaine-Related Disorders
  • Impulsive Behavior
  • Cues
  • Serotonin
  84 Scopus citations

• Serotonin neurobiology in cocaine use disorder

  Cunningham, K. A., Howell, L. L. & Anastasio, N. C., 2020, Handbook of Behavioral Neuroscience. Elsevier B.V., p. 745-802 58 p. (Handbook of Behavioral Neuroscience; vol. 31).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Neurobiology
  • Cocaine
  • Serotonin
  • Serotonin Receptors
  • Brain Diseases

• Special Issue on Precision Medicine for Brain Cancer in ACS Chemical Neuroscience

  Nilsson, C. L. & Cunningham, K. A., Jan 17 2018, In: ACS chemical neuroscience. 9, 1, p. 5 1 p.

  Research output: Contribution to journal › Editorial › peer-review
  2 Scopus citations

• Suppression of cocaine relapse-like behaviors upon pimavanserin and lorcaserin co-administration

  Anastasio, N. C., Sholler, D. J., Fox, R. G., Stutz, S. J., Merritt, C. R., Bjork, J. M., Moeller, F. G. & Cunningham, K. A., May 15 2020, In: Neuropharmacology. 168, 108009.

  Research output: Contribution to journal › Article › peer-review

  • pimavanserin
  • lorcaserin
  • Cocaine
  • Recurrence
  • Self Administration
  4 Scopus citations

• Synergism between a serotonin 5-HT_2A receptor (5-HT _2AR) antagonist and 5-HT_2CR agonist suggests new pharmacotherapeutics for cocaine addiction

  Cunningham, K. A., Anastasio, N. C., Fox, R. G., Stutz, S. J., Bubar, M. J., Swinford, S. E., Watson, C. S., Gilbertson, S. R., Rice, K. C., Rosenzweig-Lipson, S. & Moeller, F. G., Jan 16 2013, In: ACS chemical neuroscience. 4, 1, p. 110-121 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Serotonin 5-HT2 Receptor Antagonists
  • Cocaine-Related Disorders
  • Cocaine
  • Receptor, Serotonin, 5-HT2A
  • Cues
  66 Scopus citations

• Synthesis and activity of functionalizable derivatives of the serotonin (5-HT) 5-HT_2A receptor (5-HT_2AR) antagonist M100907

  Gilbertson, S. R., Chen, Y. C., Soto, C. A., Yang, Y., Rice, K. C., Cunningham, K. A. & Anastasio, N. C., May 1 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 8, p. 1381-1385 5 p.

  Research output: Contribution to journal › Article › peer-review

  • volinanserin
  • Serotonin 5-HT2 Receptor Antagonists
  • Receptor, Serotonin, 5-HT2A
  • Serotonin
  • Derivatives
  5 Scopus citations

• Targeting the 5-ht_2c receptor in biological context and the current state of 5-ht_2c receptor ligand development

  Wold, E. A., Wild, C. T., Cunningham, K. A. & Zhou, J., 2019, In: Current topics in medicinal chemistry. 19, 16, p. 1381-1398 18 p.

  Research output: Contribution to journal › Review article › peer-review

  • lorcaserin
  • Serotonin
  • Artificial Receptors
  • Serotonin 5-HT2 Receptor Agonists
  • Receptor, Serotonin, 5-HT2C
  12 Scopus citations

• The 5-HT_2A receptor (5-HT_2AR) regulates impulsive action and cocaine cue reactivity in Male Sprague-Dawley rats

  Sholler, D. J., Stutz, S. J., Fox, R. G., Boone, E. L., Wang, Q., Rice, K. C., Gerard Moeller, F., Anastasio, N. C. & Cunningham, K. A., Jan 2019, In: Journal of Pharmacology and Experimental Therapeutics. 368, 1, p. 41-49 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2A
  • Cocaine
  • Cues
  • Sprague Dawley Rats
  • pimavanserin
  9 Scopus citations

• Translating pharmacology into therapeutics to fight the opioid crisis

  Marek, G. J., Cunningham, K. A. & Rasmussen, K., 2019, In: Journal of Pharmacology and Experimental Therapeutics. 371, 2, p. 394-395 2 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access