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• A multi-omic systems approach to elucidating Yersinia virulence mechanisms

  Ansong, C., Schrimpe-Rutledge, A. C., Mitchell, H. D., Chauhan, S., Jones, M. B., Kim, Y. M., McAteer, K., Deatherage Kaiser, B. L., Dubois, J. L., Brewer, H. M., Frank, B. C., McDermott, J. E., Metz, T. O., Peterson, S. N., Smith, R. D., Motin, V. L. & Adkins, J. N., 2013, In: Molecular BioSystems. 9, 1, p. 44-54 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pseudotuberculosis
  • Yersinia pestis
  • Yersinia
  • Systems Analysis
  • Virulence
  25 Scopus citations

• An asymptomatic patient with Fatal infertility carried a swedish strain of Chlamydia trachomatis with additional deletion in the plasmid orf1 that belonged to a different MLST sequence type

  Feodorova, V. A., Zaitsev, S. S., Saltykov, Y. V., Sultanakhmedov, E. S., Bakulev, A. L., Ulyanov, S. S. & Motin, V. L., Jul 2019, In: Microorganisms. 7, 7, 187.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Multilocus Sequence Typing
  • Chlamydia trachomatis
  • Infertility
  • Plasmids
  • Alleles
  2 Scopus citations

• A Replication-Defective human type 5 adenovirus-based trivalent vaccine confers complete protection against plague in mice and nonhuman primates

  Sha, J., Kirtley, M. L., Klages, C., Erova, T. E., Telepnev, M., Ponnusamy, D., Fitts, E. C., Baze, W. B., Sivasubramani, S. K., Lawrence, W. S., Patrikeev, I., Peel, J. E., Andersson, J. A., Kozlova, E. V., Tiner, B. L., Peterson, J. W., Mcwilliams, D., Patel, S., Rothe, E., Motin, V. L. & 1 others, Chopra, A. K., Jul 2016, In: Clinical and Vaccine Immunology. 23, 7, p. 586-600 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Human Adenoviruses
  • Plague
  • Primates
  • Vaccines
  • Antigens
  12 Scopus citations

• Assessment of live plague vaccine candidates

  Feodorova, V. A., Sayapina, L. V. & Motin, V. L., Apr 1 2016, Methods in Molecular Biology. Humana Press Inc., p. 487-498 12 p. (Methods in Molecular Biology; vol. 1403).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Plague Vaccine
  • Plague
  • Vaccines
  • Yersinia pestis
  • USSR
  2 Scopus citations

• Binding of LcrV protein from Yersinia pestis to human T-cells induces apoptosis, which is completely blocked by specific antibodies

  Abramov, V. M., Kosarev, I. V., Motin, V. L., Khlebnikov, V. S., Vasilenko, R. N., Sakulin, V. K., Machulin, A. V., Uversky, V. N. & Karlyshev, A. V., Feb 1 2019, In: International Journal of Biological Macromolecules. 122, p. 1062-1070 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia LcrV protein
  • Interferons
  • Apoptosis
  • Antibody
  • Cell death
  2 Scopus citations

• Combinational deletion of three membrane protein-encoding genes highly attenuates Yersinia pestis while retaining immunogenicity in a mouse model of pneumonic plague

  Tiner, B. L., Sha, J., Kirtley, M. L., Erova, T. E., Popov, V. L., Baze, W. B., van Lier, C. J., Ponnusamy, D., Andersson, J. A., Motin, V. L., Chauhan, S. & Chopra, A. K., 2015, In: Infection and immunity. 83, 4, p. 1318-1338 21 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Plague
  • Membrane Proteins
  • Genes
  • Lethal Dose 50
  13 Scopus citations

• Comparative omics-driven genome annotation refinement: Application across yersiniae

  Schrimpe-Rutledge, A. C., Jones, M. B., Chauhan, S., Purvine, S. O., Sanford, J. A., Monroe, M. E., Brewer, H. M., Payne, S. H., Ansong, C., Frank, B. C., Smith, R. D., Peterson, S. N., Motin, V. L. & Adkins, J. N., Mar 27 2012, In: PloS one. 7, 3, e33903.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia
  • Genes
  • Genome
  • genome
  • Pseudogenes
  30 Scopus citations

• CRP-mediated carbon catabolite regulation of Yersinia pestis biofilm formation is enhanced by the carbon storage regulator protein, CsrA

  Willias, S. P., Chauhan, S., Lo, C. C., Chain, P. S. G. & Motin, V. L., Aug 25 2015, In: PloS one. 10, 8, e0135481.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Biofilms
  • carbon sequestration
  • biofilm
  • Carbon
  20 Scopus citations

• Evaluation of protective potential of Yersinia pestis outer membrane protein antigens as possible candidates for a new-generation recombinant plague vaccine

  Erova, T. E., Rosenzweig, J. A., Sha, J., Suarez, G., Sierra, J. C., Kirtley, M. L., Van Lier, C. J., Telepnev, M. V., Motin, V. L. & Chopra, A. K., Feb 2013, In: Clinical and Vaccine Immunology. 20, 2, p. 227-238 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Synthetic Vaccines
  • Plague Vaccine
  • Yersinia pestis
  • Plague
  • Rats
  20 Scopus citations

• Expression and association of the Yersinia pestis translocon proteins, YopB and YopD, are facilitated by nanolipoprotein particles

  Coleman, M. A., Cappuccio, J. A., Blanchette, C. D., Gao, T., Arroyo, E., Hinz, A. K., Bourguet, F. A., Segelke, B., Hoeprich, P. D., Huser, T., Laurence, T. A., Motin, V. L. & Chromy, B. A., Mar 2016, In: PloS one. 11, 3, e0150166.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Membrane Proteins
  • Pathogens
  • Membranes
  • Proteins
  4 Scopus citations

• First detection of chlamydia trachomatis 'Swedish' variant (nvCT) in a Russian couple with infertility

  Feodorova, V., Sultanakhmedov, E., Saltykov, Y., Zaitsev, S., Utz, S., Corbel, M., Gaydos, C., Quinn, T. & Motin, V., 2018, In: Open Microbiology Journal. 12, 1, p. 343-352 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Chlamydia trachomatis
  • Infertility
  • Genitalia
  • Fertilization in Vitro
  • anti-IgG
  1 Scopus citations

• Further characterization of a highly attenuated Yersinia pestis CO92 mutant deleted for the genes encoding Braun lipoprotein and plasminogen activator protease in murine alveolar and primary human macrophages

  van Lier, C. J., Tiner, B. L., Chauhan, S., Motin, V. L., Fitts, E. C., Huante, M. B., Endsley, J. J., Ponnusamy, D., Sha, J. & Chopra, A. K., Mar 1 2015, In: Microbial Pathogenesis. 80, p. 27-38 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Plasminogen Activators
  • Lipoproteins
  • Peptide Hydrolases
  • Macrophages
  6 Scopus citations

• High Potency of Novel Polymeric Adjuvant in Eliciting of the Immune Response in Mice to Major Antigens of Chlamydia and Yersinia

  Feodorov, V. A., Lyapina, A. M., Ulianova, O. V., Polyanina, T. I., Eliseev, Y. Y. & Motin, V. L., 2012, In: Procedia in Vaccinology. 6, p. 93-97 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Polyoxidonium
  • Yersinia
  • Chlamydia
  • Antigens
  • Piperazine

• Humoral and cellular immune responses to Yersinia pestis Pla antigen in humans immunized with live plague vaccine

  Feodorova, V. A., Lyapina, A. M., Khizhnyakova, M. A., Zaitsev, S. S., Sayapina, L. V., Arseneva, T. E., Trukhachev, A. L., Lebedeva, S. A., Telepnev, M. V., Ulianova, O. V., Lyapina, E. P., Ulyanov, S. S. & Motin, V. L., Jun 2018, In: PLoS neglected tropical diseases. 12, 6, e0006511.

  Research output: Contribution to journal › Article › peer-review

  • Plague Vaccine
  • Yersinia pestis
  • Humoral Immunity
  • Cellular Immunity
  • Peptides
  8 Scopus citations

• Marmots and yersinia pestis strains in two plague endemic areas of tien shan mountains

  Sariyeva, G., Bazarkanova, G., Maimulov, R., Abdikarimov, S., Kurmanov, B., Abdirassilova, A., Shabunin, A., Sagiyev, Z., Dzhaparova, A., Abdel, Z., Mussagaliyeva, R., Morand, S., Motin, V. & Kosoy, M., Jul 2 2019, In: Frontiers in Veterinary Science. 6, JUL, 207.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Marmota
  • Yersinia pestis
  • Plague
  • plague
  • mountains
  2 Scopus citations

• MPLEx: A method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

  Burnum-Johnson, K. E., Kyle, J. E., Eisfeld, A. J., Casey, C. P., Stratton, K. G., Gonzalez, J. F., Habyarimana, F., Negretti, N. M., Sims, A. C., Chauhan, S., Thackray, L. B., Halfmann, P. J., Walters, K. B., Kim, Y. M., Zink, E. M., Nicora, C. D., Weitz, K. K., Webb-Robertson, B. J. M., Nakayasu, E. S., Ahmer, B. & 8 others, Konkel, M. E., Motin, V., Baric, R. S., Diamond, M. S., Kawaoka, Y., Waters, K. M., Smith, R. D. & Metz, T. O., Jan 30 2017, In: Analyst. 142, 3, p. 442-448 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Metabolites
  • Pathogens
  • Lipids
  • pathogen
  • Proteins
  13 Scopus citations

• Multi-locus sequence analysis reveals a novel sequence type of Chlamydia trachomatis in Saratov Region, Russia

  Feodorova, V. A., Zaitsev, S. S., Saltykov, Y. V., Ulyanov, S. S. & Motin, V. L., Sep 2019, In: New Microbes and New Infections. 31, 100584.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  • Russia
  • Chlamydia trachomatis
  • Sequence Analysis
  • Asymptomatic Diseases
  • Chlamydia Infections

• New insights into autoinducer-2 signaling as a virulence regulator in a mouse model of pneumonic plague

  Fitts, E. C., Andersson, J. A., Kirtley, M. L., Sha, J., Erova, T. E., Chauhan, S., Motin, V. L. & Chopra, A. K., Nov 1 2016, In: mSphere. 1, 6, e00342-16.

  Research output: Contribution to journal › Article › peer-review

  • N-octanoylhomoserine lactone
  • Plague
  • Virulence
  • Yersinia pestis
  • Bacterial Genes
  6 Scopus citations

• New promising targets for synthetic omptin-based peptide vaccine against gram-negative pathogens

  Feodorova, V. A., Lyapina, A. M., Zaitsev, S. S., Khizhnyakova, M. A., Sayapina, L. V., Ulianova, O. V., Ulyanov, S. S. & Motin, V. L., Jun 2019, In: Vaccines. 7, 2, 36.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • omptin outer membrane protease
  • Subunit Vaccines
  • Epitopes
  • Peptide Hydrolases
  • Enterobacteriaceae Infections
  3 Scopus citations

• New role for FDA-approved drugs in combating antibiotic-resistant bacteria

  Andersson, J. A., Fitts, E. C., Kirtley, M. L., Ponnusamy, D., Peniche, A. G., Dann, S. M., Motin, V. L., Chauhan, S., Rosenzweig, J. A., Sha, J. & Chopra, A. K., Jun 2016, In: Antimicrobial agents and chemotherapy. 60, 6, p. 3717-3729 13 p.

  Research output: Contribution to journal › Article › peer-review

  • United States Food and Drug Administration
  • Yersinia pestis
  • Trifluoperazine
  • Bacteria
  • Anti-Bacterial Agents
  18 Scopus citations

• Phylogeny and classification of Yersinia pestis through the lens of strains from the Plague Foci of commonwealth of independent states

  Kutyrev, V. V., Eroshenko, G. A., Motin, V. L., Nosov, N. Y., Krasnov, J. M., Kukleva, L. M., Nikiforov, K. A., Al'khova, Z. V., Oglodin, E. G. & Guseva, N. P., May 25 2018, In: Frontiers in Microbiology. 9, MAY, 1106.

  Research output: Contribution to journal › Article › peer-review

  • Commonwealth of Independent States
  • Yersinia pestis
  • Plague
  • Phylogeny
  • Lenses
  22 Scopus citations

• Plague vaccines: Current developments and future perspectives

  Feodorova, V. A. & Motin, V. L., 2012, In: Emerging Microbes and Infections. 1, e36.

  Research output: Contribution to journal › Review article › peer-review

  • Plague Vaccine
  • Yersinia pestis
  • Plague
  • Subunit Vaccines
  • Humoral Immunity
  37 Scopus citations

• Polymorphism of the cysteine protease YopT from Yersinia pestis

  Platonov, M. E., Svetoch, T. E., Evseeva, V. V., Knyazeva, A. I., Dentovskaya, S. V., Motin, V. L., Uversky, V. N. & Anisimov, A. P., Feb 1 2016, In: Protein and Peptide Letters. 23, 4, p. 379-385 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Plague
  • Polymorphism
  • Cysteine Proteases
  • Protein Isoforms

• Serologic Markers for Long-Term Immunity in Humans Vaccinated with Live Yersinia pestis EV NIIEG

  Feodorov, V. A., Lyapina, A. M., Ulianova, O. V., Lyapina, E. P., Sayapina, L. V., Lyapin, M. N., Shcherbakov, A. A., Telepnev, M. V. & Motin, V. L., 2012, In: Procedia in Vaccinology. 6, p. 10-13 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Plague
  • Immunity
  • Plague Vaccine
  • Antigens
  1 Scopus citations

• Studying salmonellae and yersiniae host-pathogen interactions using integrated 'omics and modeling

  Ansong, C., Deatherage, B. L., Hyduke, D., Schmidt, B., McDermott, J. E., Jones, M. B., Chauhan, S., Charusanti, P., Kim, Y. M., Nakayasu, E. S., Li, J., Kidwai, A., Niemann, G., Brown, R. N., Metz, T. O., McAteer, K., Heffron, F., Peterson, S. N., Motin, V., Palsson, B. O. & 2 others, Smith, R. D. & Adkins, J. N., 2012, Systems Biology. Katze, M. G. (ed.). p. 21-41 21 p. (Current Topics in Microbiology and Immunology; vol. 363).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Yersinia
  • Host-Pathogen Interactions
  • Host Specificity
  • Salmonella
  • Systems Biology
  10 Scopus citations

• Two isoforms of Yersinia pestis plasminogen activator Pla: Intraspecies distribution, intrinsic disorder propensity, and contribution to virulence

  Dentovskaya, S. V., Platonov, M. E., Svetoch, T. E., Kopylov, P. K., Kombarova, T. I., Ivanov, S. A., Shaikhutdinova, R. Z., Kolombet, L. V., Chauhan, S., Ablamunits, V. G., Motin, V. L., Uversky, V. N. & Anisimov, A. P., Dec 2016, In: PloS one. 11, 12, e0168089.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • plasminogen activator
  • Plasminogen Activators
  • Virulence
  • virulence
  5 Scopus citations

• Urogenital Chlamydia trachomatis multilocus sequence types and genovar distribution in chlamydia infected patients in a multi-ethnic region of Saratov, Russia

  Feodorova, V. A., Konnova, S. S., Saltykov, Y. V., Zaitsev, S. S., Subbotina, I. A., Polyanina, T. I., Ulyanov, S. S., Lamers, S. L., Gaydos, C. A., Quinn, T. C. & Motin, V. L., Apr 2018, In: PloS one. 13, 4, e0195386.

  Research output: Contribution to journal › Article › peer-review

  • Chlamydia trachomatis
  • Chlamydia
  • Russia
  • Genes
  • Polymorphism
  5 Scopus citations

• Yersinia pestis in the age of big data

  Yang, R. & Motin, V., Oct 1 2016, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 918. p. 257-272 16 p. (Advances in Experimental Medicine and Biology; vol. 918).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Big Data
  • Yersinia pestis
  • Big data
  • Metabolomics
  • Proteomics
  2 Scopus citations