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• 30-Day Readmissions in Hospitalized Adults With Asthma Exacerbations: Insights From the Nationwide Readmission Database

  Veeranki, S. P., Sharma, K., Ohabughiro, M. U., Mehta, H. B., Adhikari, D., Kuo, Y. F. & Calhoun, W. J., Nov 1 2016, In: Chest. 150, 5, p. 1162-1165 4 p.

  Research output: Contribution to journal › Letter › peer-review
  6 Scopus citations

• Activation of Human Peripheral Blood Eosinophils by Cytokines in a Comparative Time-Course Proteomic/Phosphoproteomic Study

  Soman, K. V., Stafford, S. J., Pazdrak, K., Wu, Z., Luo, X., White, W. I., Wiktorowicz, J. E., Calhoun, W. J. & Kurosky, A., Aug 4 2017, In: Journal of Proteome Research. 16, 8, p. 2663-2679 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics
  • Eosinophils
  • Blood
  • Chemical activation
  • Cytokines
  9 Scopus citations

• Assessing and Evaluating Multidisciplinary Translational Teams: A Mixed Methods Approach

  Wooten, K. C., Rose, R. M., Ostir, G. V., Calhoun, W. J., Ameredes, B. T. & Brasier, A. R., 2014, In: Evaluation and the Health Professions. 37, 1, p. 33-49 17 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Benralizumab - A humanized mAb to IL-5Rα with enhanced antibody-dependent cell-mediated cytotoxicity - A novel approach for the treatment of asthma

  Ghazi, A., Trikha, A. & Calhoun, W. J., Jan 2012, In: Expert Opinion on Biological Therapy. 12, 1, p. 113-118 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • benralizumab
  • Cytotoxicity
  • Antibody-Dependent Cell Cytotoxicity
  • Interleukin-5
  • Asthma
  110 Scopus citations

• Biologic Therapy in Chronic Obstructive Pulmonary Disease

  Tripple, J., McCracken, J. & Calhoun, W., May 1 2017, In: Immunology and Allergy Clinics of North America. 37, 2, p. 345-355 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Biological Therapy
  • Chronic Obstructive Pulmonary Disease
  • Inflammation
  • Environmental Exposure
  • Biological Factors
  5 Scopus citations

• Biologic therapy in the management of asthma

  McCracken, J. L., Tripple, J. W. & Calhoun, W. J., Aug 1 2016, In: Current opinion in allergy and clinical immunology. 16, 4, p. 375-382 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Biological Therapy
  • Asthma
  • Biological Factors
  • Leukotrienes
  • Bronchodilator Agents
  28 Scopus citations

• Chronic Respiratory Disease and Cognitive Impairment in Older Mexican Adults

  Veeranki, S., Downer, B., Jupiter, D., Kuo, Y. F., Raji, M., Calhoun, W. & Wong, R., Nov 1 2019, In: Neurology India. 67, 6, p. 1539-1542 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Cognitive Dysfunction
  • Chronic Disease
  • Logistic Models
  • Outcome Assessment (Health Care)
  • Odds Ratio

• Clinical burden and predictors of asthma exacerbations in patients on guideline-based steps 4-6 asthma therapy in the TENOR cohort

  Calhoun, W. J., Haselkorn, T., Mink, D. R., Miller, D. P., Dorenbaum, A. & Zeiger, R. S., Mar 2014, In: Journal of Allergy and Clinical Immunology: In Practice. 2, 2, p. 193-200.e3

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Guidelines
  • Odds Ratio
  • Quality of Life
  • Therapeutics
  31 Scopus citations

• Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: The BASALT randomized controlled trial

  Calhoun, W. J., Ameredes, B. T., King, T. S., Icitovic, N., Bleecker, E. R., Castro, M., Cherniack, R. M., Chinchilli, V. M., Craig, T., Denlinger, L., DiMango, E. A., Engle, L. L., Fahy, J. V., Grant, J. A., Israel, E., Jarjour, N., Kazani, S. D., Kraft, M., Kunselman, S. J., Lazarus, S. C. & 15 others, Lemanske, R. F., Lugogo, N., Martin, R. J., Meyers, D. A., Moore, W. C., Pascual, R., Peters, S. P., Ramsdell, J., Sorkness, C. A., Sutherland, E. R., Szefler, S. J., Wasserman, S. I., Walter, M. J., Wechsler, M. E. & Boushey, H. A., Sep 5 2012, In: JAMA - Journal of the American Medical Association. 308, 10, p. 987-997 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Adrenal Cortex Hormones
  • Asthma
  • Randomized Controlled Trials
  • Biomarkers
  • Physicians
  125 Scopus citations

• Conclusions and future directions

  Calhoun, W. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  1 Scopus citations

• Conclusions and future directions

  Calhoun, W. J. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Cytokine-induced glucocorticoid resistance from eosinophil activation: Protein phosphatase 5 modulation of glucocorticoid receptor phosphorylation and signaling

  Pazdrak, K., Straub, C., Maroto, R., Stafford, S., White, W. I., Calhoun, W. J. & Kurosky, A., Nov 15 2016, In: Journal of Immunology. 197, 10, p. 3782-3791 10 p.

  Research output: Contribution to journal › Article › peer-review

  • protein phosphatase 5
  • Glucocorticoid Receptors
  • Eosinophils
  • Phosphorylation
  • Cytokines
  21 Scopus citations

• Diagnosis and management of asthma in adults a review

  McCracken, J., Veeranki, S. P., Ameredes, B. & Calhoun, W., Jul 18 2017, In: JAMA - Journal of the American Medical Association. 318, 3, p. 279-290 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Asthma
  • Adrenal Cortex Hormones
  • Biological Factors
  • Airway Obstruction
  • reslizumab
  68 Scopus citations

• Effects of acute ethanol exposure on cytokine production by primary airway smooth muscle cells

  Kaphalia, L., Kalita, M., Kaphalia, B. S. & Calhoun, W. J., Feb 1 2016, In: Toxicology and Applied Pharmacology. 292, p. 85-93 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Acetaldehyde
  • Pulmonary diseases
  • Esters
  • Cells
  • Muscle
  7 Scopus citations

• Ethanol Exposure Impairs AMPK Signaling and Phagocytosis in Human Alveolar Macrophages: Role of Ethanol Metabolism

  Kaphalia, L., Srinivasan, M. P., Kakumanu, R. D., Kaphalia, B. S. & Calhoun, W. J., 2019, In: Alcoholism: Clinical and Experimental Research. 43, 8, p. 1682-1694 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Alveolar Macrophages
  • Oxidative stress
  • Metabolism
  • AMP-Activated Protein Kinases
  • Phagocytosis
  1 Scopus citations

• Ethanol metabolism, oxidative stress, and endoplasmic reticulum stress responses in the lungs of hepatic alcohol dehydrogenase deficient deer mice after chronic ethanol feeding

  Kaphalia, L., Boroumand, N., Hyunsu, J., Kaphalia, B. S. & Calhoun, W. J., Jun 1 2014, In: Toxicology and Applied Pharmacology. 277, 2, p. 109-117 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxidative stress
  • Peromyscus
  • Alcohol Dehydrogenase
  • Metabolism
  • Endoplasmic Reticulum Stress
  18 Scopus citations

• Forced Oscillometry: A New Tool for Assessing Airway Function—Is It Ready for Prime Time?

  Ram, J., Pineda-Cely, J. & Calhoun, W. J., Nov 1 2019, In: Journal of Allergy and Clinical Immunology: In Practice. 7, 8, p. 2861-2862 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations

• Heterogeneity of asthma in society

  Divekar, R. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Vitamin D
  • Asthma
  • Immunologic Factors
  • Animals
  • Obesity
  4 Scopus citations

• Heterogeneity of asthma in society

  Divekar, R. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Vitamin D
  • Asthma
  • Immunologic Factors
  • Animals
  • Obesity

• Heterogeneity of response to therapy

  Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Asthma
  • Physiology
  • Restoration
  • Therapeutics
  • History

• Heterogeneity of response to therapy

  Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Asthma
  • Physiology
  • Restoration
  • Therapeutics
  • History

• HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma

  Zein, J., Gaston, B., Bazeley, P., DeBoer, M. D., Igo, R. P., Bleecker, E. R., Meyers, D., Comhair, S., Marozkina, N. V., Cotton, C., Patel, M., Alyamani, M., Xu, W., Busse, W. W., Calhoun, W. J., Ortega, V., Hawkins, G. A., Castro, M., Chung, K. F., Fahy, J. V. & 12 others, Fitzpatrick, A. M., Israel, E., Jarjour, N. N., Levy, B., Mauger, D. T., Moore, W. C., Noel, P., Peters, S. P., Teague, W. G., Wenzel, S. E., Erzurum, S. C. & Sharifi, N., Jan 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2187-2193 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glucocorticoids
  • Asthma
  • Genotype
  • Androgens
  • 3-Hydroxysteroid Dehydrogenases
  3 Scopus citations

• Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients

  Silkoff, P. E., Laviolette, M., Singh, D., FitzGerald, J. M., Kelsen, S., Backer, V., Porsbjerg, C. M., Girodet, P. O., Berger, P., Kline, J. N., Chupp, G., Susulic, V. S., Barnathan, E. S., Baribaud, F., Loza, M. J., Strambu, I., Lam, S., Eich, A., Ludwig-Sengpiel, A., Leigh, R. & 4 others, Dransfield, M., Calhoun, W., Hussaini, A. & Chanez, P., Sep 2017, In: Journal of Allergy and Clinical Immunology. 140, 3, p. 710-719 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Eosinophils
  • Biomarkers
  • Nitric Oxide
  • Inflammation
  28 Scopus citations

• Impact of Age and Sex on Outcomes and Hospital Cost of Acute Asthma in the United States, 2011-2012

  Zein, J. G., Udeh, B. L., Teague, W. G., Koroukian, S. M., Schlitz, N. K., Bleecker, E. R., Busse, W. B., Calhoun, W. J., Castro, M., Comhair, S. A., Fitzpatrick, A. M., Israel, E., Wenzel, S. E., Holguin, F., Gaston, B. M. & Erzurum, S. C., Jun 2016, In: PloS one. 11, 6, e0157301.

  Research output: Contribution to journal › Article › peer-review

  • Hospital Costs
  • asthma
  • Asthma
  • gender
  • Costs
  32 Scopus citations

• Improving Quality of Acute Asthma Care in US Hospitals: Changes Between 1999-2000 and 2012-2013

  Hasegawa, K., Tsugawa, Y., Clark, S., Eastin, C. D., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Ahn, J., Aurora, T., Brenner, B., Brown, M. A., Calhoun, W., Gough, J. E., Gharib, A., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S. & 11 others, Nowak, R., Pei, V., Press, V. G., Probst, B. D., Ramratnam, S. K., Tallar, M., Teuber, S. S., Trent, S. A., Villarreal, R., Watase, T. & Youngquist, S., Jul 1 2016, In: Chest. 150, 1, p. 112-122 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Guidelines
  • Length of Stay
  • Inpatients
  • Hospitalized Child
  10 Scopus citations

• Introduction to asthma and phenotyping

  Pillai, R. A. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Asthma
  • Phenotype
  • Airway Obstruction
  • Patient Care
  • Inflammation

• Introduction to asthma and phenotyping

  Pillai, R. A. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Asthma
  • Phenotype
  • Airway Obstruction
  • Patient Care
  • Inflammation
  5 Scopus citations

• Key observations from the NHLBI Asthma Clinical Research Network

  Szefler, S. J., Chinchilli, V. M., Israel, E., Denlinger, L. C., Lemanske, R. F., Calhoun, W. & Peters, S. P., May 2012, In: Thorax. 67, 5, p. 450-455 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • National Heart, Lung, and Blood Institute (U.S.)
  • Asthma
  • Tiotropium Bromide
  • Leukotriene Antagonists
  • Clinical Trials
  10 Scopus citations

• Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study

  The ADEPT Investigators, 2016, In: Respiratory Research. 17, 1, p. 1-12 12 p., 43.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Biomarkers
  • Nitric Oxide
  • Phenotype
  • Bronchodilator Agents
  19 Scopus citations

• Management of Acute Asthma in Adults in 2020

  Zaidan, M. F., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 563-564 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  1 Scopus citations

• Mucosal bromodomain-containing protein 4 mediates aeroallergen-induced inflammation and remodeling

  Tian, B., Hosoki, K., Liu, Z., Yang, J., Zhao, Y., Sun, H., Zhou, J., Rytting, E., Kaphalia, L., Calhoun, W. J., Sur, S. & Brasier, A. R., Apr 2019, In: Journal of Allergy and Clinical Immunology. 143, 4, p. 1380-1394.e9

  Research output: Contribution to journal › Article › peer-review

  • Dander
  • Cats
  • Myofibroblasts
  • Inflammation
  • Airway Remodeling
  15 Scopus citations

• Outpatient Management of Chronic Asthma in 2020

  Tripple, J. W., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 561-562 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  3 Scopus citations

• Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling

  Zhao, Y., Tian, B., Sun, H., Zhang, J., Zhang, Y., Ivannikov, M., Motamedi, M., Liu, Z., Zhou, J., Kaphalia, L., Calhoun, W. J., Maroto, R. & Brasier, A. R., Aug 15 2019, In: Journal of Proteomics. 205, 103415.

  Research output: Contribution to journal › Article › peer-review

  • Airway Remodeling
  • Bronchoalveolar Lavage Fluid
  • Homeostasis
  • Pericytes
  • Blood Vessels
  11 Scopus citations

• Post-transplant native pneumonectomy for interstitial fibrosis and small cell lung cancer

  Li, R. T., Zahedi, S., Trieu, J., Lea, A. S., Calhoun, W. J., Duarte, A. G., Zhao, J. & Okereke, I. C., Dec 1 2017, In: Journal of Thoracic Disease. 9, 12, p. E1096-E1099

  Research output: Contribution to journal › Article › peer-review

  • Pneumonectomy
  • Lung Transplantation
  • Small Cell Lung Carcinoma
  • Lung Neoplasms
  • Fibrosis

• Race is associated with differences in airway inflammation in patients with asthma

  Nyenhuis, S. M., Krishnan, J. A., Berry, A., Calhoun, W. J., Chinchilli, V. M., Engle, L., Grossman, N., Holguin, F., Israel, E., Kittles, R. A., Kraft, M., Lazarus, S. C., Lehman, E. B., Mauger, D. T., Moy, J. N., Peters, S. P., Phipatanakul, W., Smith, L. J., Sumino, K., Szefler, S. J. & 4 others, Wechsler, M. E., Wenzel, S., White, S. R. & Ackerman, S. J., Jul 2017, In: Journal of Allergy and Clinical Immunology. 140, 1, p. 257-265.e11

  Research output: Contribution to journal › Article › peer-review

  • African Americans
  • European Continental Ancestry Group
  • Asthma
  • Inflammation
  • Sputum
  21 Scopus citations

• Severe asthma: Lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program

  Jarjour, N. N., Erzurum, S. C., Bleecker, E. R., Calhoun, W. J., Castro, M., Comhair, S. A. A., Chung, K. F., Curran-Everett, D., Dweik, R. A., Fain, S. B., Fitzpatrick, A. M., Gaston, B. M., Israel, E., Hastie, A., Hoffman, E. A., Holguin, F., Levy, B. D., Meyers, D. A., Moore, W. C., Peters, S. P. & 4 others, Sorkness, R. L., Teague, W. G., Wenzel, S. E. & Busse, W. W., Feb 15 2012, In: American Journal of Respiratory and Critical Care Medicine. 185, 4, p. 356-362 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • National Heart, Lung, and Blood Institute (U.S.)
  • Asthma
  • Bronchoscopy
  171 Scopus citations

• Sleep quality and asthma control and quality of life in non-severe and severe asthma

  Luyster, F. S., Teodorescu, M., Bleecker, E., Busse, W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S., Israel, E., Strollo, P. J. & Wenzel, S. E., Dec 2012, In: Sleep and Breathing. 16, 4, p. 1129-1137 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Quality Control
  • Sleep
  • Asthma
  • Gastroesophageal Reflux
  • Quality of Life
  54 Scopus citations

• Strategies for molecular classification of asthma using bipartite network analysis of cytokine expression

  Pillai, R. R., Divekar, R., Brasier, A., Bhavnani, S. & Calhoun, W. J., Oct 2012, In: Current Allergy and Asthma Reports. 12, 5, p. 388-395 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Cytokines
  • Health Care Costs
  • Signs and Symptoms
  • Data Analysis
  15 Scopus citations

• The spectrum of asthma: an introduction.

  Calhoun, W. J., 2014, In: Advances in experimental medicine and biology. 795, p. 1-4 4 p.

  Research output: Contribution to journal › Editorial › peer-review

• Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data

  Wu, W., Bleecker, E., Moore, W., Busse, W. W., Castro, M., Chung, K. F., Calhoun, W. J., Erzurum, S., Gaston, B., Israel, E., Curran-Everett, D. & Wenzel, S. E., May 2014, In: Journal of Allergy and Clinical Immunology. 133, 5, p. 1280-1288 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Lung
  • Unsupervised Machine Learning
  • Cluster Analysis
  • Asthma and Nasal Polyps
  152 Scopus citations

• Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study

  For the ADEPT (Airways Disease Endotyping for Personalized Therapeutics) & U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) investigators, Dec 15 2016, In: Respiratory Research. 17, 1, 165.

  Research output: Contribution to journal › Article › peer-review

  • Cluster Analysis
  • Asthma
  • Phenotype
  • Inflammation
  • Interleukin-13
  49 Scopus citations

• Why do asthma patients cough? New insights into cough in allergic asthma

  Puebla-Neira, D. & Calhoun, W. J., Sep 2019, In: Journal of Allergy and Clinical Immunology. 144, 3, p. 656-657 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations