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• ¹H, ¹³C, ¹⁵N backbone and side-chain resonance assignment of Nostoc sp. C139A variant of the heme–nitric oxide/oxygen binding (H-NOX) domain

  Alexandropoulos, I. I., Argyriou, A. I., Marousis, K. D., Topouzis, S., Papapetropoulos, A. & Spyroulias, G. A., Oct 1 2016, In: Biomolecular NMR Assignments. 10, 2, p. 395-400 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Nostoc
  • Oxides
  • Oxygen
  • Soluble Guanylyl Cyclase
  • Heme
  2 Scopus citations

• 3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics

  Abdollahi Govar, A., Törő, G., Szaniszlo, P., Pavlidou, A., Bibli, S. I., Thanki, K., Resto, V. A., Chao, C., Hellmich, M. R., Szabo, C., Papapetropoulos, A. & Módis, K., Feb 1 2020, In: British Journal of Pharmacology. 177, 4, p. 866-883 18 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-mercaptopyruvic acid
  • Energy Metabolism
  • Endothelial Cells
  • Hydrogen Sulfide
  • Small Interfering RNA
  7 Scopus citations

• Angiopoietin-2 enhances survival in experimental sepsis induced by multidrug-resistant Pseudomonas aeruginosa

  Tzepi, I. M., Giamarellos-Bourboulis, E. J., Carrer, D. P., Tsaganos, T., Claus, R. A., Vaki, I., Pelekanou, A., Kotsaki, A., Tziortzioti, V., Topouzis, S., Bauer, M. & Papapetropoulos, A., Nov 1 2012, In: Journal of Pharmacology and Experimental Therapeutics. 343, 2, p. 278-287 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Angiopoietin-2
  • Pseudomonas aeruginosa
  • Sepsis
  • Tumor Necrosis Factor-alpha
  • Neutrophil Infiltration
  16 Scopus citations

• A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization

  Palmer, G. M., Tiran, Z., Zhou, Z. Z., Capozzi, M. E., Park, W., Coletta, C., Pyriochou, A., Kliger, Y., Levy, O., Borukhov, I., Dewhirst, M. W., Rotman, G., Penn, J. S. & Papapetropoulos, A., Mar 2012, In: British Journal of Pharmacology. 165, 6, p. 1891-1903 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Angiopoietins
  • Retinal Neovascularization
  • Peptides
  • Angiopoietin-2
  • Neoplasms
  10 Scopus citations

• A selective and sensitive method for quantification of endogenous polysulfide production in biological samples

  Bibli, S. I., Luck, B., Zukunft, S., Wittig, J., Chen, W., Xian, M., Papapetropoulos, A., Hu, J. & Fleming, I., Sep 2018, In: Redox Biology. 18, p. 295-304 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • polysulfide
  • Sulfur
  • Gasotransmitters
  • Cystathionine
  • Endothelial cells
  28 Scopus citations

• Association study of the CTH 1364 G>T polymorphism with coronary artery disease in the Greek population

  Giannakopoulou, E., Konstantinou, F., Ragia, G., Gerontitis, Z., Tavridou, A., Papapetropoulos, A., Mikroulis, D. & Manolopoulos, V. G., Jan 1 2019, In: Drug Metabolism and Personalized Therapy. 34, 1, 20180033.

  Research output: Contribution to journal › Article › peer-review

  • Coronary Artery Bypass
  • Coronary Artery Disease
  • Genotype
  • Population
  • Cystathionine
  2 Scopus citations

• ATP-sensitive potassium channel activation induces angiogenesis in vitro and in vivo

  Umaru, B., Pyriochou, A., Kotsikoris, V., Papapetropoulos, A. & Topouzis, S., Jul 1 2015, In: Journal of Pharmacology and Experimental Therapeutics. 354, 1, p. 79-87 9 p.

  Research output: Contribution to journal › Article › peer-review

  • C-Type Natriuretic Peptide
  • KATP Channels
  • SG 209
  • Vascular Endothelial Growth Factor C
  • In Vitro Techniques
  14 Scopus citations

• Backbone and side chain NMR assignments of the H-NOX domain from Nostoc sp. in complex with BAY58-2667 (cinaciguat)

  Makrynitsa, G. I., Argyriou, A. I., Dalkas, G., Georgopoulou, D. A., Bantzi, M., Giannis, A., Papapetropoulos, A. & Spyroulias, G. A., 2020, (Accepted/In press) In: Biomolecular NMR Assignments.

  Research output: Contribution to journal › Article › peer-review

  • BAY 58-2667
  • Nostoc
  • Nuclear magnetic resonance
  • Heme
  • Soluble Guanylyl Cyclase

• Cardioprotection by H₂S Donors: Nitric Oxide-Dependent and -Independent Mechanisms

  Chatzianastasiou, A., Bibli, S. I., Andreadou, I., Efentakis, P., Kaludercic, N., Wood, M. E., Whiteman, M., Lisa, F. D., Daiber, A., Manolopoulos, V. G., Szabó, C. & Papapetropoulos, D. A., Sep 2016, In: Journal of Pharmacology and Experimental Therapeutics. 358, 3, p. 431-440 10 p.

  Research output: Contribution to journal › Article › peer-review

  • sodium sulfide
  • Nitric Oxide Donors
  • GYY 4137
  • cyclophilin D
  • Permeability
  42 Scopus citations

• Cardioprotection by H₂S engages a cGMP-dependent protein kinase G/phospholamban pathway

  Bibli, S. I., Andreadou, I., Chatzianastasiou, A., Tzimas, C., Sanoudou, D., Kranias, E., Brouckaert, P., Coletta, C., Szabo, C., Kremastinos, D. T., Iliodromitis, E. K. & Papapetropoulos, A., Jun 1 2015, In: Cardiovascular research. 106, 3, p. 432-442 11 p.

  Research output: Contribution to journal › Article › peer-review

  • sodium bisulfide
  • phospholamban
  • Cyclic GMP-Dependent Protein Kinases
  • Cyclic GMP-Dependent Protein Kinase Type I
  • Rabbits
  51 Scopus citations

• Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase

  Peleli, M., Bibli, S. I., Li, Z., Chatzianastasiou, A., Varela, A., Katsouda, A., Zukunft, S., Bucci, M., Vellecco, V., Davos, C. H., Nagahara, N., Cirino, G., Fleming, I., Lefer, D. J. & Papapetropoulos, A., Jun 2020, In: Biochemical Pharmacology. 176, 113833.

  Research output: Contribution to journal › Article › peer-review

  • 3-mercaptopyruvic acid
  • Phenotype
  • Cystathionine
  • Lyases
  • Cardiovascular system
  4 Scopus citations

• cGMP-Dependent Protein Kinase Contributes to Hydrogen Sulfide-Stimulated Vasorelaxation

  Bucci, M., Papapetropoulos, A., Vellecco, V., Zhou, Z., Zaid, A., Giannogonas, P., Cantalupo, A., Dhayade, S., Karalis, K. P., Wang, R., Feil, R. & Cirino, G., Dec 28 2012, In: PloS one. 7, 12, e53319.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vasodilation
  • sodium bisulfide
  • cGMP-dependent protein kinase
  • Cyclic GMP-Dependent Protein Kinases
  • Hydrogen Sulfide
  88 Scopus citations

• Comparison of the effects of e-cigarette vapor with cigarette smoke on lung function and inflammation in mice

  Glynos, C., Bibli, S. I., Katsaounou, P., Pavlidou, A., Magkou, C., Karavana, V., Topouzis, S., Kalomenidis, I., Zakynthinos, S. & Papapetropoulos, A., Nov 2018, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 315, 5, p. L662-L672

  Research output: Contribution to journal › Article › peer-review

  • Electronic Nicotine Delivery Systems
  • Smoke
  • Tobacco Products
  • Pneumonia
  • Bronchoalveolar Lavage Fluid
  36 Scopus citations

• Cooperative Interactions Between NO and H₂S: Chemistry, Biology, Physiology, Pathophysiology

  Kevil, C., Cortese-Krott, M. M., Nagy, P., Papapetropoulos, A., Feelisch, M. & Szabo, C., Jan 1 2017, Nitric Oxide: Biology and Pathobiology: Third Edition. Elsevier Inc., p. 57-83 27 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Sulfides
  • Physiology
  • polysulfide
  • Chemical activation
  • Cyclic GMP-Dependent Protein Kinases
  12 Scopus citations

• Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” (Redox Biol. (2017) 13 (94–162)(S2213231717303373)(10.1016/j.redox.2017.05.007))

  Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., Apr 2018, In: Redox Biology. 14, p. 694-696 3 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Oxidation-Reduction
  • Technology
  • Publications
  • European Union
  • Emotions
  4 Scopus citations

• Cystathionine-β-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach

  Chao, C., Zatarain, J. R., Ding, Y., Coletta, C., Mrazek, A. A., Druzhyna, N., Johnson, P., Chen, H., Hellmich, J. L., Asimakopoulou, A., Yanagi, K., Olah, G., Szoleczky, P., Törö, G., Bohanon, F. J., Cheema, M., Lewis, R., Eckelbarger, D., Ahmad, A., Módis, K. & 6 others, Untereiner, A., Szczesny, B., Papapetropoulos, A., Zhou, J., Hellmich, M. R. & Szabo, C., 2016, In: Molecular Medicine. 22, p. 361-379 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Aminooxyacetic Acid
  • Cystathionine
  • Prodrugs
  • Colonic Neoplasms
  • Neoplasms
  24 Scopus citations

• Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis

  Bibli, S. I., Hu, J., Sigala, F., Wittig, I., Heidler, J., Zukunft, S., Tsilimigras, D. I., Randriamboavonjy, V., Wittig, J., Kojonazarov, B., Schürmann, C., Siragusa, M., Siuda, D., Luck, B., Abdel Malik, R., Filis, K. A., Zografos, G., Chen, C., Wang, D. W., Pfeilschifter, J. & 4 others, Brandes, R. P., Szabo, C., Papapetropoulos, A. & Fleming, I., Jan 2 2019, In: Circulation. 139, 1, p. 101-114 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystathionine
  • Lyases
  • RNA-Binding Proteins
  • Atherosclerosis
  • Endothelial Cells
  28 Scopus citations

• D -Penicillamine modulates hydrogen sulfide (H₂S) pathway through selective inhibition of cystathionine-γ-lyase

  Brancaleone, V., Esposito, I., Gargiulo, A., Vellecco, V., Asimakopoulou, A., Citi, V., Calderone, V., Gobbetti, T., Perretti, M., Papapetropoulos, A., Bucci, M. & Cirino, G., May 1 2016, In: British Journal of Pharmacology. 173, 9, p. 1556-1565 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cystathionine
  • Lyases
  • Hydrogen Sulfide
  • Penicillamine
  • Inhibition (Psychology)
  18 Scopus citations

• Drug resistance induces the upregulation of H₂S-producing enzymes in HCT116 colon cancer cells

  Untereiner, A. A., Pavlidou, A., Druzhyna, N., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Mar 2018, In: Biochemical Pharmacology. 149, p. 174-185 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cells
  • Fluorouracil
  • Drug Resistance
  • Colonic Neoplasms
  • Up-Regulation
  28 Scopus citations

• Endothelial-tumor cell interaction in brain and CNS malignancies

  Peleli, M., Moustakas, A. & Papapetropoulos, A., Oct 1 2020, In: International journal of molecular sciences. 21, 19, p. 1-28 28 p., 7371.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Tumors
  • Cells
  • tumors
  • brain
  • Cell Communication

• Epigenetics-by-Sex Interaction for Coronary Artery Disease Risk Conferred by the Cystathionine γ-Lyase Gene Promoter Methylation

  Giannakopoulou, E., Konstantinou, F., Ragia, G., Tavridou, A., Karaglani, M., Chatzaki, E., Papapetropoulos, A., Mikroulis, D. & Manolopoulos, V. G., Dec 1 2017, In: OMICS A Journal of Integrative Biology. 21, 12, p. 741-748 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Methylation
  • Cystathionine
  • Lyases
  • Genes
  • Epigenomics
  10 Scopus citations

• European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

  Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., Oct 2017, In: Redox Biology. 13, p. 94-162 69 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Oxidation-Reduction
  • Oxidative stress
  • Reactive Nitrogen Species
  • Technology
  • Reactive Oxygen Species
  136 Scopus citations

• Exposure to cigarette smoke abrogates the beneficial effect of ischemic postconditioning

  Bibli, S. I., Andreadou, I., Glynos, C., Chatzianastasiou, A., Toumpanakis, D., Zakynthinos, S., Vasilakopoulos, T., Iliodromitis, E. K. & Papapetropoulos, A., 2016, In: American Journal of Physiology - Heart and Circulatory Physiology. 311, 5, p. H1321-H1332

  Research output: Contribution to journal › Article › peer-review

  • Ischemic Postconditioning
  • Smoke
  • Tobacco Products
  • Air
  • Conditioning (Psychology)
  9 Scopus citations

• Extending the translational potential of targeting NO/cGMP-regulated pathways in the CVS

  Papapetropoulos, A., Hobbs, A. J. & Topouzis, S., Mar 2015, In: British Journal of Pharmacology. 172, 6, p. 1397-1414 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Phosphodiesterase 5 Inhibitors
  • Nobel Prize
  • Diabetic Cardiomyopathies
  • Optimism
  • Duchenne Muscular Dystrophy
  19 Scopus citations

• From primordial gas to the medicine cabinet

  Papapetropoulos, A., Wallace, J. L. & Wang, R., Feb 1 2020, In: British Journal of Pharmacology. 177, 4, p. 715-719 5 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

  • Hydrogen Sulfide
  • Gases
  • Medicine

• Generation and characterization of a CRISPR/Cas9-induced 3-mst deficient zebrafish

  Katsouda, A., Peleli, M., Asimakopoulou, A., Papapetropoulos, A. & Beis, D., Feb 2020, In: Biomolecules. 10, 2, 317.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 3-mercaptopyruvic acid
  • Clustered Regularly Interspaced Short Palindromic Repeats
  • Zebrafish
  • polysulfide
  • Oxidative stress
  1 Scopus citations

• Guanylyl cyclase activation reverses resistive breathing-induced lung injury and inflammation

  Glynos, C., Toumpanakis, D., Loverdos, K., Karavana, V., Zhou, Z., Magkou, C., Dettoraki, M., Perlikos, F., Pavlidou, A., Kotsikoris, V., Topouzis, S., Theocharis, S. E., Brouckaert, P., Giannis, A., Papapetropoulos, A. & Vassilakopoulos, T., Jun 1 2015, In: American journal of respiratory cell and molecular biology. 52, 6, p. 762-771 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Soluble Guanylyl Cyclase
  • Guanylate Cyclase
  • Lung Injury
  • Chemical activation
  • Respiration
  14 Scopus citations

• Hydrogen sulfide: An endogenous regulator of the immune system

  Dilek, N., Papapetropoulos, A., Toliver-Kinsky, T. & Szabo, C., Nov 2020, In: Pharmacological Research. 161, 105119.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Hydrogen Sulfide
  • Immune System
  • Cystathionine
  • Immune System Diseases
  • 3-mercaptopyruvic acid

• Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation

  Coletta, C., Papapetropoulos, A., Erdelyi, K., Olah, G., Módis, K., Panopoulos, P., Asimakopoulou, A., Gerö, D., Sharina, I., Martin, E. & Szabo, C., Jun 5 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 23, p. 9161-9166 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydrogen Sulfide
  • Vasodilation
  • Endothelium
  • Guanosine Monophosphate
  • Nitric Oxide
  384 Scopus citations

• Hydrogen sulfide and PKG in ischemia–reperfusion injury: sources, signaling, accelerators and brakes

  Andreadou, I., Iliodromitis, E. K., Szabo, C. & Papapetropoulos, A., Sep 1 2015, In: Basic Research in Cardiology. 110, 5, 52.

  Research output: Contribution to journal › Editorial › peer-review

  • Cyclic GMP-Dependent Protein Kinases
  • Hydrogen Sulfide
  • Wounds and Injuries
  12 Scopus citations

• Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP₂)

  Ha, J., Xu, Y., Kawano, T., Hendon, T., Baki, L., Garai, S., Papapetropoulos, A., Thakur, G. A., Plant, L. D. & Logothetis, D. E., Mar 9 2018, In: Journal of Biological Chemistry. 293, 10, p. 3546-3561 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydrogen Sulfide
  • Phosphatidylinositols
  • Cysteine
  • Phospholipids
  • Gasotransmitters
  5 Scopus citations

• Hydrogen sulfide preserves endothelial nitric oxide synthase function by inhibiting proline-rich kinase 2: Implications for cardiomyocyte survival and cardioprotection

  Bibli, S. I., Szabo, C., Chatzianastasiou, A., Luck, B., Zukunft, S., Fleming, I. & Papapetropoulos, A., Dec 2017, In: Molecular pharmacology. 92, 6, p. 718-730 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Focal Adhesion Kinase 2
  • Hydrogen Sulfide
  • Nitric Oxide Synthase Type III
  • Proline
  • Cardiac Myocytes
  7 Scopus citations

• International union of basic and clinical pharmacology. CII: Pharmacological modulation of H₂S levels: H₂s donors and H₂S biosynthesis inhibitors

  Szabo, C. & Papapetropoulos, A., Oct 1 2017, In: Pharmacological reviews. 69, 4, p. 497-564 68 p.

  Research output: Contribution to journal › Article › peer-review

  • Clinical Pharmacology
  • Gasotransmitters
  • Cystathionine
  • 2-(6-methoxy-napthalen-2-yl)-propionic acid 4-thiocarbamoyl-phenyl ester
  • Pharmacology
  110 Scopus citations

• Inventing new therapies without reinventing the wheel: the power of drug repurposing

  Papapetropoulos, A. & Szabo, C., 2018, In: British Journal of Pharmacology. 175, 2, p. 165-167 3 p.

  Research output: Contribution to journal › Editorial › peer-review

  • Drug Repositioning
  • Therapeutics
  19 Scopus citations

• Investigating and re-evaluating the role of glycogen synthase kinase 3 beta kinase as a molecular target for cardioprotection by using novel pharmacological inhibitors

  Nikolaou, P. E., Boengler, K., Efentakis, P., Vouvogiannopoulou, K., Zoga, A., Gaboriaud-Kolar, N., Myrianthopoulos, V., Alexakos, P., Kostomitsopoulos, N., Rerras, I., Tsantili-Kakoulidou, A., Skaltsounis, A. L., Papapetropoulos, A., Iliodromitis, E. K., Schulz, R. & Andreadou, I., Jun 1 2019, In: Cardiovascular research. 115, 7, p. 1228-1243 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glycogen Synthase Kinase 3 beta
  • Phosphotransferases
  • Pharmacology
  • 6-bromoindirubin-3'-oxime
  • Autophagy-Related Proteins
  11 Scopus citations

• Levosimendan prevents doxorubicin-induced cardiotoxicity in time- and dose-dependent manner: Implications for inotropy

  Efentakis, P., Varela, A., Chavdoula, E., Sigala, F., Sanoudou, D., Tenta, R., Gioti, K., Kostomitsopoulos, N., Papapetropoulos, A., Tasouli, A., Farmakis, D., Davos, C. H., Klinakis, A., Suter, T., Cokkinos, D. V., Iliodromitis, E. K., Wenzel, P. & Andreadou, I., Mar 1 2020, In: Cardiovascular research. 116, 3, p. 576-591 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Simendan
  • Cardiotoxicity
  • Doxorubicin
  • phospholamban
  • Nitric Oxide Synthase Type III
  5 Scopus citations

• Mercaptopyruvate acts as endogenous vasodilator independently of 3-mercaptopyruvate sulfurtransferase activity

  Mitidieri, E., Tramontano, T., Gurgone, D., Citi, V., Calderone, V., Brancaleone, V., Katsouda, A., Nagahara, N., Papapetropoulos, A., Cirino, G., d'Emmanuele di Villa Bianca, R. & Sorrentino, R., May 1 2018, In: Nitric Oxide - Biology and Chemistry. 75, p. 53-59 7 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-mercaptopyruvic acid
  • Vasodilator Agents
  • N(G)-iminoethylornithine
  • Cystathionine
  • Endothelium
  16 Scopus citations

• Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells

  Szczesny, B., Marcatti, M., Ahmad, A., Montalbano, M., Brunyánszki, A., Bibli, S. I., Papapetropoulos, A. & Szabo, C., Dec 1 2018, In: Scientific reports. 8, 1, 914.

  Research output: Contribution to journal › Article › peer-review

  • Z-Form DNA
  • DNA-Binding Proteins
  • Mitochondrial DNA
  • DNA Damage
  • Oxidative Stress
  29 Scopus citations

• Nitric oxide regulates cytokine induction in the diaphragm in response to inspiratory resistive breathing

  Sigala, I., Zacharatos, P., Boulia, S., Toumpanakis, D., Michailidou, T., Parthenis, D., Roussos, C., Papapetropoulos, A., Hussain, S. N. & Vassilakopoulos, T., Nov 15 2012, In: Journal of Applied Physiology. 113, 10, p. 1594-1603 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Diaphragm
  • Research Ethics Committees
  • Respiration
  • NG-Nitroarginine Methyl Ester
  • Nitric Oxide
  16 Scopus citations

• Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: A novel mechanism for an old drug

  Bibli, S. I., Papapetropoulos, A., Iliodromitis, E. K., Daiber, A., Randriamboavonjy, V., Steven, S., Brouckaert, P., Chatzianastasiou, A., Kypreos, K. E., Hausenloy, D. J., Fleming, I. & Andreadou, I., Mar 1 2019, In: Cardiovascular research. 115, 3, p. 625-636 12 p.

  Research output: Contribution to journal › Article › peer-review

  • cyclophilin D
  • Nitrosation
  • Nitroglycerin
  • Nitric Oxide Synthase Type III
  • Pharmaceutical Preparations
  11 Scopus citations

• Pharmacological tools for hydrogen sulphide research: A brief, introductory guide for beginners

  Papapetropoulos, A., Whiteman, M. & Cirino, G., Mar 2015, In: British Journal of Pharmacology. 172, 6, p. 1633-1637 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Hydrogen Sulfide
  • Pharmacology
  • Research Personnel
  • Health
  51 Scopus citations

• Pharmacology of the 'gasotransmitters' NO, CO and H ₂ S: Translational opportunities

  Papapetropoulos, A., Foresti, R. & Ferdinandy, P., Jan 1 2015, In: British Journal of Pharmacology. 172, 6, p. 1395-1396 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  21 Scopus citations

• Phosphinodithioate and phosphoramidodithioate hydrogen sulfide donors

  Whiteman, M., Perry, A., Zhou, Z., Bucci, M., Papapetropoulos, A., Cirino, G. & Wood, M. E., 2015, In: Handbook of Experimental Pharmacology. 230, p. 337-363 27 p.

  Research output: Contribution to journal › Article › peer-review

  • phosphorodithioic acid
  • GYY 4137
  • Hydrogen Sulfide
  • sodium sulfide
  • Cystathionine
  37 Scopus citations

• Reciprocal regulation of eNOS, H₂S and CO-synthesizing enzymes in human atheroma: Correlation with plaque stability and effects of simvastatin

  Sigala, F., Efentakis, P., Karageorgiadi, D., Filis, K., Zampas, P., Iliodromitis, E. K., Zografos, G., Papapetropoulos, A. & Andreadou, I., Aug 1 2017, In: Redox Biology. 12, p. 70-81 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Simvastatin
  • Atherosclerotic Plaques
  • Carbon Monoxide
  • Cystathionine beta-Synthase
  • Heme Oxygenase-1
  20 Scopus citations

• Reduced adipose tissue H₂S in obesity

  Katsouda, A., Szabo, C. & Papapetropoulos, A., Feb 2018, In: Pharmacological Research. 128, p. 190-199 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystathionine
  • 3-mercaptopyruvic acid
  • Lyases
  • Adipose Tissue
  • Obesity
  11 Scopus citations

• Regulation and role of endogenously produced hydrogen sulfide in angiogenesis

  Katsouda, A., Bibli, S. I., Pyriochou, A., Szabo, C. & Papapetropoulos, A., Nov 1 2016, In: Pharmacological Research. 113, p. 175-185 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Hydrogen Sulfide
  • Vascular Endothelial Growth Factor A
  • Enzymes
  • Endothelial Cells
  • KATP Channels
  42 Scopus citations

• Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide

  Zhou, Z., Martin, E., Sharina, I., Esposito, I., Szabo, C., Bucci, M., Cirino, G. & Papapetropoulos, A., Sep 1 2016, In: Pharmacological Research. 111, p. 556-562 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydrogen Sulfide
  • Soluble Guanylyl Cyclase
  • Oxidation-Reduction
  • Nitric Oxide
  • BAY 58-2667
  40 Scopus citations

• Regulation of vascular tone, angiogenesis and cellular bioenergetics by the 3-mercaptopyruvate sulfurtransferase/H₂S pathway: Functional impairment by hyperglycemia and restoration by dl-α-lipoic acid

  Coletta, C., Módis, K., Szczesny, B., Brunyánszki, A., Oláh, G., Rios, E. C. S., Yanagi, K., Ahmad, A., Papapetropoulos, A. & Szabo, C., Feb 18 2015, In: Molecular Medicine. 21, p. 1-14 14 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-mercaptopyruvic acid
  • Thioctic Acid
  • Hyperglycemia
  • Energy Metabolism
  • Blood Vessels
  69 Scopus citations

• Role of cGMP in hydrogen sulfide signaling

  Bibli, S. I., Yang, G., Zhou, Z., Wang, R., Topouzis, S. & Papapetropoulos, A., Apr 30 2015, In: Nitric Oxide - Biology and Chemistry. 46, p. 7-13 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Hydrogen Sulfide
  • Cyclic Nucleotides
  • Guanylate Cyclase
  • Physiology
  • Ion Channels
  27 Scopus citations

• Role of the cystathionine γ lyase/hydrogen sulfide pathway in human melanoma progression

  Panza, E., De Cicco, P., Armogida, C., Scognamiglio, G., Gigantino, V., Botti, G., Germano, D., Napolitano, M., Papapetropoulos, A., Bucci, M., Cirino, G. & Ianaro, A., Jan 1 2015, In: Pigment Cell and Melanoma Research. 28, 1, p. 61-72 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystathionine
  • Lyases
  • Hydrogen Sulfide
  • Melanoma
  • cysteine lyase
  56 Scopus citations