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• A bacteriophage T4 nanoparticle-based dual vaccine against anthrax and plague

  Tao, P., Mahalingam, M., Zhu, J., Moayeri, M., Sha, J., Lawrence, W. S., Leppla, S. H., Chopra, A. K. & Rao, V. B., Sep 1 2018, In: mBio. 9, 5, e01926-18.

  Research output: Contribution to journal › Article › peer-review

  • Plague Vaccine
  • Anthrax Vaccines
  • Anthrax
  • Bacteriophage T4
  • Plague
  17 Scopus citations

• Actin cross-linking domain of Aeromonas hydrophila repeat in toxin A (RtxA) induces host cell rounding and apoptosis

  Suarez, G., Khajanchi, B. K., Sierra, J. C., Erova, T. E., Sha, J. & Chopra, A. K., Sep 15 2012, In: Gene. 506, 2, p. 369-376 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Actins
  • Apoptosis
  • Vibrio
  • Operon
  24 Scopus citations

• A prokaryotic-eukaryotic hybrid viral vector for delivery of large cargos of genes and proteins into human cells

  Zhu, J., Tao, P., Mahalingam, M., Sha, J., Kilgore, P., Chopra, A. K. & Rao, V., Aug 21 2019, In: Science Advances. 5, 8, eaax0064.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • viruses
  • genes
  • delivery
  • proteins
  • biotin
  3 Scopus citations

• Combating multidrug-resistant pathogens with host-directed nonantibiotic therapeutics

  Andersson, J. A., Sha, J., Kirtley, M. L., Reyes, E., Fitts, E. C., Dann, S. M. & Chopra, A. K., Jan 2018, In: Antimicrobial agents and chemotherapy. 62, 1, e01943.

  Research output: Contribution to journal › Article › peer-review

  • Plague
  • Pharmaceutical Preparations
  • Macrophages
  • Acinetobacter baumannii
  • Klebsiella pneumoniae
  8 Scopus citations

• Combinational deletion of three membrane protein-encoding genes highly attenuates Yersinia pestis while retaining immunogenicity in a mouse model of pneumonic plague

  Tiner, B. L., Sha, J., Kirtley, M. L., Erova, T. E., Popov, V. L., Baze, W. B., van Lier, C. J., Ponnusamy, D., Andersson, J. A., Motin, V. L., Chauhan, S. & Chopra, A. K., 2015, In: Infection and immunity. 83, 4, p. 1318-1338 21 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Plague
  • Membrane Proteins
  • Genes
  • Lethal Dose 50
  13 Scopus citations

• DNA adenine methyltransferase (Dam) controls the expression of the cytotoxic enterotoxin (act) gene of Aeromonas hydrophila via tRNA modifying enzyme-glucose-inhibited division protein (GidA)

  Erova, T. E., Kosykh, V. G., Sha, J. & Chopra, A. K., May 1 2012, In: Gene. 498, 2, p. 280-287 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Enterotoxins
  • Adenine
  • Methyltransferases
  • Transfer RNA
  12 Scopus citations

• Further characterization of a highly attenuated Yersinia pestis CO92 mutant deleted for the genes encoding Braun lipoprotein and plasminogen activator protease in murine alveolar and primary human macrophages

  van Lier, C. J., Tiner, B. L., Chauhan, S., Motin, V. L., Fitts, E. C., Huante, M. B., Endsley, J. J., Ponnusamy, D., Sha, J. & Chopra, A. K., Mar 1 2015, In: Microbial Pathogenesis. 80, p. 27-38 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Plasminogen Activators
  • Lipoproteins
  • Peptide Hydrolases
  • Macrophages
  6 Scopus citations

• High-throughput, signature-tagged mutagenic approach to identify novel virulence factors of Yersinia pestis CO92 in a mouse model of infection

  Ponnusamy, D., Fitts, E. C., Sha, J., Erova, T. E., Kozlova, E. V., Kirtley, M. L., Tiner, B. L., Andersson, J. A. & Chopra, A. K., 2015, In: Infection and immunity. 83, 5, p. 2065-2081 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Lethal Dose 50
  • Virulence Factors
  • Plague
  • Infection
  10 Scopus citations

• Intramuscular immunization of mice with a live-Attenuated triple mutant of yersinia pestis co92 induces robust humoral and cell-mediated immunity to completely protect animals against pneumonic plague

  Tiner, B. L., Sha, J., Ponnusamy, D., Baze, W. B., Fitts, E. C., Popov, V. L., Van Lier, C. J., Erova, T. E. & Chopra, A. K., Dec 2015, In: Clinical and Vaccine Immunology. 22, 12, p. 1255-1268 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Immunization
  • Yersinia pestis
  • Plague
  • Animals
  • Cellular Immunity
  9 Scopus citations

• New host-directed therapeutics for the treatment of Clostridioides difficile infection

  Andersson, J. A., Peniche, A. G., Galindo, C. L., Boonma, P., Sha, J., Luna, R. A., Savidge, T. C., Chopra, A. K. & Dann, S. M., Mar 1 2020, In: mBio. 11, 2, e00053-20.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Amoxapine
  • Infection
  • Interleukin-33
  • Pharmaceutical Preparations
  • Doxapram

• T6SS and ExoA of flesh-eating Aeromonas hydrophila in peritonitis and necrotizing fasciitis during mono- And polymicrobial infections

  Fernández-Bravo, A., Kilgore, P. B., Andersson, J. A., Blears, E., Figueras, M. J., Hasan, N. A., Colwell, R. R., Sha, J. & Chopra, A. K., Nov 26 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 48, p. 24084-24092 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Type VI Secretion Systems
  • Aeromonas hydrophila
  • Exotoxins
  • Necrotizing Fasciitis
  • Peritonitis
  5 Scopus citations

• The two-component QseBC signalling system regulates in vitro and in vivo virulence of Aeromonas hydrophila

  Khajanchi, B. K., Kozlova, E. V., Sha, J., Popov, V. L. & Chopra, A. K., Jan 2012, In: Microbiology. 158, 1, p. 259-271 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Quorum Sensing
  • Virulence
  • N-(3-oxohexanoyl)-3-aminodihydro-2(3H)-furanone
  • N-octanoylhomoserine lactone
  45 Scopus citations