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Erratum: Treatment of human glioblastoma with a live attenuated zika virus vaccine candidate (mBio, (2018) 9(5), e01683-18, 10.1128/mBio.01683-18)
Chen, Q., Wu, J., Ye, Q., Ma, F., Zhu, Q., Wu, Y., Shan, C., Xie, X., Li, D., Zhan, X., Li, C., Li, X. F., Qin, X., Zhao, T., Wu, H., Shi, P. Y., Man, J. & Qin, C. F., Mar 1 2019, In: mBio. 10, 2, e00433-19.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Erratum: Zika virus has oncolytic activity against glioblastoma stem cells [The Journal of Experimental Medicine, 214, 10, (2017)] DOI: 10.1084/jem.20171093
Zhu, Z., Gorman, M. J., McKenzie, L. D., Chai, J. N., Hubert, C. G., Prager, B. C., Fernandez, E., Richner, J. M., Zhang, R., Shan, C., Tycksen, E., Wang, X., Shi, P. Y., Diamond, M. S., Rich, J. N. & Chheda, M. G., 2017, In: Journal of Experimental Medicine. 214, 10, p. 3145 1 p.Research output: Contribution to journal › Comment/debate › peer-review
6 Scopus citations -
Enterovirus 71 VPg uridylation uses a two-molecular mechanism of 3D polymerase
Sun, Y., Wang, Y., Shan, C., Chen, C., Xu, P., Song, M., Zhou, H., Yang, C., Xu, W., Shi, P. Y., Zhang, B. & Lou, Z., Dec 2012, In: Journal of virology. 86, 24, p. 13662-13671 10 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Discovery of potent non-nucleoside inhibitors of dengue viral RNA-dependent rna polymerase from fragment screening and structure-guided design
Lim, S. P., Noble, C. G., Nilar, S., Shi, P. Y. & Yokokawa, F., 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 187-198 12 p. (Advances in Experimental Medicine and Biology; vol. 1062).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design
Yokokawa, F., Nilar, S., Noble, C. G., Lim, S. P., Rao, R., Tania, S., Wang, G., Lee, G., Hunziker, J., Karuna, R., Manjunatha, U., Shi, P-Y. & Smith, P. W., Apr 28 2016, In: Journal of Medicinal Chemistry. 59, 8, p. 3935-3952 18 p.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Dimerization of flavivirus NS4B protein
Zou, J., Xie, X., Lee, L. T., Chandrasekaran, R., Reynaud, A., Yap, L., Wang, Q. Y., Dong, H., Kang, C., Yuan, Z., Lescar, J. & Shi, P. Y., Mar 2014, In: Journal of virology. 88, 6, p. 3379-3391 13 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
Difficulties and advancements in developing drugs for the treatment of dengue fever
Noble, C. G. & Shi, P. Y., 2013, In: Expert Opinion on Orphan Drugs. 1, 12, p. 947-949 3 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Did Zika Virus Mutate to Cause Severe Outbreaks?
Rossi, S. L., Ebel, G. D., Shan, C., Shi, P. Y. & Vasilakis, N., Oct 2018, In: Trends in Microbiology. 26, 10, p. 877-885 9 p.Research output: Contribution to journal › Review article › peer-review
12 Scopus citations -
Development of a FACS-based assay for evaluating antiviral potency of compound in dengue infected peripheral blood mononuclear cells
Fu, Y., Chen, Y. L., Herve, M., Gu, F., Shi, P. Y. & Blasco, F., Feb 2014, In: Journal of Virological Methods. 196, p. 18-24 7 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone
Li, X. F., Dong, H. L., Wang, H. J., Huang, X. Y., Qiu, Y. F., Ji, X., Ye, Q., Li, C., Liu, Y., Deng, Y. Q., Jiang, T., Cheng, G., Zhang, F. C., Davidson, A. D., Song, Y. J., Shi, P. Y. & Qin, C. F., Dec 1 2018, In: Nature communications. 9, 1, 673.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
Development and characterization of a stable luciferase dengue virus for high-throughput screening
Zou, G., Xu, H. Y., Qing, M., Wang, Q. Y. & Shi, P. Y., Jul 1 2011, In: Antiviral research. 91, 1, p. 11-19 9 p.Research output: Contribution to journal › Article › peer-review
83 Scopus citations -
Development and characterization of a stable eGFP enterovirus 71 for antiviral screening
Shang, B., Deng, C., Ye, H., Xu, W., Yuan, Z., Shi, P. Y. & Zhang, B., Feb 2013, In: Antiviral research. 97, 2, p. 198-205 8 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Detection and quantification of flavivirus NS5 methyl-transferase activities
Lim, S. P., Bodenreider, C. & Shi, P. Y., Jul 18 2013, Antiviral Methods and Protocols. p. 249-268 20 p. (Methods in Molecular Biology; vol. 1030).Research output: Chapter in Book/Report/Conference proceeding › Chapter
5 Scopus citations -
Design, Synthesis, and Biological Evaluation of Substituted 4,6-Dihydrospiro[[1,2,3]triazolo[4,5- b]pyridine-7,3′-indoline]-2′,5(3 H)-dione Analogues as Potent NS4B Inhibitors for the Treatment of Dengue Virus Infection
Xu, J., Xie, X., Ye, N., Zou, J., Chen, H., White, M. A., Shi, P. Y. & Zhou, J., Sep 12 2019, In: Journal of medicinal chemistry. 62, 17, p. 7941-7960 20 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Dengue Therapeutics, Chemoprophylaxis, and Allied Tools: State of the Art and Future Directions
Whitehorn, J., Yacoub, S., Anders, K. L., Macareo, L. R., Cassetti, M. C., Nguyen Van, V. C., Shi, P. Y., Wills, B. & Simmons, C. P., Aug 28 2014, In: PLoS neglected tropical diseases. 8, 8, e3025.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission
Pompon, J., Manuel, M., Ng, G. K., Wong, B., Shan, C., Manokaran, G., Soto-Acosta, R., Bradrick, S. S., Ooi, E. E., Missé, D., Shi, P. Y. & Garcia-Blanco, M. A., Jul 2017, In: PLoS pathogens. 13, 7, e1006535.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Dengue NS2A Protein Orchestrates Virus Assembly
Xie, X., Zou, J., Zhang, X., Zhou, Y., Routh, A. L., Kang, C., Popov, V. L., Chen, X., Wang, Q. Y., Dong, H. & Shi, P. Y., Nov 13 2019, In: Cell Host and Microbe. 26, 5, p. 606-622.e8Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Dengue in China: not a passing problem
Qin, C. F. & Shi, P. Y., Dec 11 2014, In: Science China Life Sciences. 57, 12, p. 1230-1231 2 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Dengue drug discovery
Shi, P. Y., Yin, Z., Nilar, S. & Keller, T. H., Oct 31 2011, Third World Diseases. Elliot, R. (ed.). p. 243-276 34 p. (Topics in Medicinal Chemistry; vol. 7).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: Implication for a trans mechanism of VPg uridylylation
Chen, C., Wang, Y., Shan, C., Sun, Y., Xu, P., Zhou, H., Yang, C., Shi, P. Y., Rao, Z., Zhang, B. & Lou, Z., May 1 2013, In: Journal of virology. 87, 10, p. 5755-5768 14 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
Crystal structure of dengue virus methyltransferase without S-adenosyl-L-methionine
Noble, C. G., Li, S. H., Dong, H., Chew, S. H. & Shi, P. Y., Nov 2014, In: Antiviral research. 111, p. 78-81 4 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Corrigendum to "Population variation of West Nile virus confers a host-specific fitness benefit in mosquitoes" [Virology 404 (2010) 89-95]
Fitzpatrick, K. A., Deardorff, E. R., Pesko, K., Brackney, D. E., Zhang, B., Bedrick, E., Shi, P. Y. & Ebel, G. D., Feb 20 2011, In: Virology. 410, 2, p. 437 1 p.Research output: Contribution to journal › Comment/debate › peer-review
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Conformational flexibility of the dengue virus RNA-Dependent RNA polymerase revealed by a complex with an inhibitor
Noble, C. G., Lim, S. P., Chen, Y. L., Liew, C. W., Yap, L., Lescar, J. & Shi, P. Y., May 2013, In: Journal of virology. 87, 9, p. 5291-5295 5 p.Research output: Contribution to journal › Article › peer-review
70 Scopus citations -
Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo
Chang, J., Schul, W., Butters, T. D., Yip, A., Liu, B., Goh, A., Lakshminarayana, S. B., Alonzi, D., Reinkensmeier, G., Pan, X., Qu, X., Weidner, J. M., Wang, L., Yu, W., Borune, N., Kinch, M. A., Rayahin, J. E., Moriarty, R., Xu, X., Shi, P. Y. & 2 others, , Jan 2011, In: Antiviral research. 89, 1, p. 26-34 9 p.Research output: Contribution to journal › Article › peer-review
69 Scopus citations -
Characterization of a candidate tetravalent vaccine based on 2’-O-methyltransferase mutants
Züst, R., Li, S. H., Xie, X., Velumani, S., Chng, M., Toh, Y. X., Zou, J., Dong, H., Shan, C., Pang, J., Qin, C. F., Newell, E. W., Shi, P. Y. & Fink, K., Jan 2018, In: PloS one. 13, 1, e0189262.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Characterization of a 2016 Clinical Isolate of Zika Virus in Non-human Primates
Li, X. F., Dong, H. L., Huang, X. Y., Qiu, Y. F., Wang, H. J., Deng, Y. Q., Zhang, N. N., Ye, Q., Zhao, H., Liu, Z. Y., Fan, H., An, X. P., Sun, S. H., Gao, B., Fa, Y. Z., Tong, Y. G., Zhang, F. C., Gao, G. F., Cao, W. C., Shi, P. Y. & 1 others, , Oct 1 2016, In: EBioMedicine. 12, p. 170-177 8 p.Research output: Contribution to journal › Article › peer-review
86 Scopus citations -
Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure
Qian, X., Nguyen, H. N., Song, M. M., Hadiono, C., Ogden, S. C., Hammack, C., Yao, B., Hamersky, G. R., Jacob, F., Zhong, C., Yoon, K. J., Jeang, W., Lin, L., Li, Y., Thakor, J., Berg, D. A., Zhang, C., Kang, E., Chickering, M., Nauen, D. & 10 others, , May 19 2016, In: Cell. 165, 5, p. 1238-1254 17 p.Research output: Contribution to journal › Article › peer-review
783 Scopus citations -
A Zika virus vaccine expressing premembrane-envelope-NS1 polyprotein
Li, A., Yu, J., Lu, M., Ma, Y., Attia, Z., Shan, C., Xue, M., Liang, X., Craig, K., Makadiya, N., He, J. J., Jennings, R., Shi, P. Y., Peeples, M. E., Liu, S. L., Boyaka, P. N. & Li, J., Dec 1 2018, In: Nature communications. 9, 1, 3067.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Axl promotes zika virus entry and modulates the antiviral state of human sertoli cells
Strange, D. P., Jiyarom, B., Zarandi, N. P., Xie, X., Baker, C., Sadri-Ardekani, H., Shi, P. Y. & Verma, S., Jul 1 2019, In: mBio. 10, 4, e01372-19.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
A translation inhibitor that suppresses dengue virus in vitro and in vivo
Wang, Q. Y., Kondreddi, R. R., Xie, X., Rao, R., Nilar, S., Xu, H. Y., Qing, M., Chang, D., Dong, H., Yokokawa, F., Lakshminarayana, S. B., Goh, A., Schul, W., Kramer, L., Keller, T. H. & Shi, P. Y., Sep 2011, In: Antimicrobial agents and chemotherapy. 55, 9, p. 4072-4080 9 p.Research output: Contribution to journal › Article › peer-review
39 Scopus citations -
A survey of core replacements in indole-based HIV-1 attachment inhibitors
Wang, T., Wallace, O. B., Zhang, Z., Fang, H., Yang, Z., Robinson, B. A., Spicer, T. P., Gong, Y. F., Blair, W. S., Shi, P. Y., Lin, P. F., Deshpande, M., Meanwell, N. A. & Kadow, J. F., Jun 1 2019, In: Bioorganic and Medicinal Chemistry Letters. 29, 11, p. 1423-1429 7 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
A single residue in the αb helix of the e protein is critical for Zika virus thermostability correspondence
Xie, D. Y., Liu, Z. Y., Nian, Q. G., Zhu, L., Wang, N., Deng, Y. Q., Zhao, H., Ji, X., Li, X. F., Wang, X., Shi, P. Y. & Qin, C. F., Dec 1 2018, In: Emerging Microbes and Infections. 7, 1, 0006.Research output: Contribution to journal › Letter › peer-review
3 Scopus citations -
A single mutation in the prM protein of Zika virus contributes to fetal microcephaly
Yuan, L., Huang, X. Y., Liu, Z. Y., Zhang, F., Zhu, X. L., Yu, J. Y., Ji, X., Xu, Y. P., Li, G., Li, C., Wang, H. J., Deng, Y. Q., Wu, M., Cheng, M. L., Ye, Q., Xie, D. Y., Li, X. F., Wang, X., Shi, W., Hu, B. & 3 others, , Nov 17 2017, In: Science. 358, 6365, p. 933-936 4 p.Research output: Contribution to journal › Article › peer-review
215 Scopus citations -
A single-dose plasmid-launched live-attenuated Zika vaccine induces protective immunity
Zou, J., Xie, X., Luo, H., Shan, C., Muruato, A. E., Weaver, S. C., Wang, T. & Shi, P. Y., Oct 2018, In: EBioMedicine. 36, p. 92-102 11 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
A Single-Dose Live-Attenuated Zika Virus Vaccine with Controlled Infection Rounds that Protects against Vertical Transmission
Xie, X., Kum, D. B., Xia, H., Luo, H., Shan, C., Zou, J., Muruato, A. E., Medeiros, D. B. A., Nunes, B. T. D., Dallmeier, K., Rossi, S. L., Weaver, S. C., Neyts, J., Wang, T., Vasconcelos, P. F. C. & Shi, P. Y., Oct 10 2018, In: Cell Host and Microbe. 24, 4, p. 487-499.e5Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
Shan, C., Muruato, A. E., Jagger, B. W., Richner, J., Nunes, B. T. D., Medeiros, D. B. A., Xie, X., Nunes, J. G. C., Morabito, K. M., Kong, W. P., Pierson, T. C., Barrett, A. D., Weaver, S. C., Rossi, S. L., Vasconcelos, P. F. C., Graham, B. S., Diamond, M. S. & Shi, P. Y., Dec 1 2017, In: Nature communications. 8, 1, 676.Research output: Contribution to journal › Article › peer-review
80 Scopus citations -
A Single Amino Acid Substitution in the Core Protein of West Nile Virus Increases Resistance to Acidotropic Compounds
Martín-Acebes, M. A., Blázquez, A. B., de Oya, N. J., Escribano-Romero, E., Shi, P. Y. & Saiz, J. C., Jul 18 2013, In: PloS one. 8, 7, e69479.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
A single amino acid in nonstructural protein NS4B Confers virulence to dengue virus in AG129 mice through enhancement of viral RNA synthesis
Grant, D., Tan, G. K., Qing, M., Ng, J. K. W., Yip, A., Zou, G., Xie, X., Yuan, Z. Y., Schreiber, J., Schul, W., Shi, P. Y. & Alonso, S., Aug 2011, In: Journal of virology. 85, 15, p. 7775-7787 13 p.Research output: Contribution to journal › Article › peer-review
67 Scopus citations -
A Rapid Zika Diagnostic Assay to Measure Neutralizing Antibodies in Patients
Shan, C., Xie, X., Ren, P., Loeffelholz, M. J., Yang, Y., Furuya, A., Dupuis, A. P., Kramer, L. D., Wong, S. J. & Shi, P. Y., Mar 1 2017, In: EBioMedicine. 17, p. 157-162 6 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
A positively selected mutation in the WNV 2K peptide confers resistance to superinfection exclusion in vivo
Campbell, C. L., Smith, D. R., Sanchez-Vargas, I., Zhang, B., Shi, P. Y. & Ebel, G. D., Sep 2014, In: Virology. 464-465, 1, p. 228-232 5 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Anti-Zika virus RNAi in neural progenitor cells
Xie, X. & Shi, P. Y., Apr 1 2019, In: Cell Research. 29, 4, p. 261-262 2 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Anti-infectives: Can cellular screening deliver?
Keller, T. H., Shi, P. Y. & Wang, Q. Y., Aug 2011, In: Current Opinion in Chemical Biology. 15, 4, p. 529-533 5 p.Research output: Contribution to journal › Review article › peer-review
22 Scopus citations -
Anti-dengue-virus activity and structure-activity relationship studies of lycorine derivatives
Wang, P., Li, L. F., Wang, Q. Y., Shang, L. Q., Shi, P. Y. & Yin, Z., Jul 2014, In: ChemMedChem. 9, 7, p. 1522-1533 12 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
A novel reporter system for neutralizing and enhancing antibody assay against dengue virus
Song, K. Y., Zhao, H., Jiang, Z. Y., Li, X. F., Deng, Y. Q., Jiang, T., Zhu, S. Y., Shi, P. Y., Zhang, B., Zhang, F. C., Qin, E. D. & Qin, C. F., Feb 18 2014, In: BMC Microbiology. 14, 1, 44.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors
Shan, C., Xie, X., Muruato, A. E., Rossi, S. L., Roundy, C. M., Azar, S. R., Yang, Y., Tesh, R. B., Bourne, N., Barrett, A. D., Vasilakis, N., Weaver, S. C. & Shi, P. Y., Jun 8 2016, In: Cell Host and Microbe. 19, 6, p. 891-900 10 p.Research output: Contribution to journal › Article › peer-review
162 Scopus citations -
An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
Xia, H., Luo, H., Shan, C., Muruato, A. E., Nunes, B. T. D., Medeiros, D. B. A., Zou, J., Xie, X., Giraldo, M. I., Vasconcelos, P. F. C., Weaver, S. C., Wang, T., Rajsbaum, R. & Shi, P. Y., Dec 1 2018, In: Nature communications. 9, 1, 414.Research output: Contribution to journal › Article › peer-review
95 Scopus citations -
An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses
Li, G., Adam, A., Luo, H., Shan, C., Cao, Z., Fontes-Garfias, C. R., Sarathy, V. V., Teleki, C., Winkelmann, E. R., Liang, Y., Sun, J., Bourne, N., Barrett, A. D. T., Shi, P. Y. & Wang, T., Dec 1 2019, In: npj Vaccines. 4, 1, 48.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
A Multiplex Microsphere Immunoassay for Zika Virus Diagnosis
Wong, S. J., Furuya, A., Zou, J., Xie, X., Dupuis, A. P., Kramer, L. D. & Shi, P. Y., Feb 1 2017, In: EBioMedicine. 16, p. 136-140 5 p.Research output: Contribution to journal › Article › peer-review
58 Scopus citations -
A multidimensional platform for the purification of non-coding RNA species
Chionh, Y. H., Ho, C. H., Pruksakorn, D., Ramesh Babu, I., Ng, C. S., Hia, F., McBee, M. E., Su, D., Pang, Y. L. J., Gu, C., Dong, H., Prestwich, E. G., Shi, P. Y., Preiser, P. R., Alonso, S. & Dedon, P. C., Sep 2013, In: Nucleic acids research. 41, 17, p. e168Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models
Shan, C., Muruato, A. E., Nunes, B. T. D., Luo, H., Xie, X., Medeiros, D. B. A., Wakamiya, M., Tesh, R. B., Barrett, A. D., Wang, T., Weaver, S. C., Vasconcelos, P. F. C., Rossi, S. L. & Shi, P. Y., Jun 1 2017, In: Nature Medicine. 23, 6, p. 763-767 5 p.Research output: Contribution to journal › Article › peer-review
159 Scopus citations