Search concepts
|
Selected Filters |
- 100 - 150 out of 196 results
- Export search results
Search results
-
Inhibition of dengue virus by targeting viral NS4B protein
Xie, X., Wang, Q. Y., Xu, H. Y., Qing, M., Kramer, L., Yuan, Z. & Shi, P. Y., Nov 2011, In: Journal of virology. 85, 21, p. 11183-11195 13 p.Research output: Contribution to journal › Article › peer-review
92 Scopus citations -
Inhibition of coronavirus entry in vitro and ex vivo by a lipid-conjugated peptide derived from the sars-cov-2 spike glycoprotein hrc domain
Outlaw, V. K., Bovier, F. T., Mears, M. C., Cajimat, M. N., Zhu, Y., Lin, M. J., Addetia, A., Lieberman, N. A. P., Peddu, V., Xie, X., Shi, P. Y., Greninger, A. L., Gellman, S. H., Bente, D. A., Moscona, A. & Porotto, M., Sep 1 2020, In: mBio. 11, 5, p. 1-14 14 p., e01935-20.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Identifying optimal capsid duplication length for the stability of reporter flaviviruses
Baker, C., Liu, Y., Zou, J., Muruato, A., Xie, X. & Shi, P. Y., Jan 1 2020, In: Emerging Microbes and Infections. 9, 1, p. 2256-2265 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Human IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability
Johnson, B., VanBlargan, L. A., Xu, W., White, J. P., Shan, C., Shi, P. Y., Zhang, R., Adhikari, J., Gross, M. L., Leung, D. W., Diamond, M. S. & Amarasinghe, G. K., Mar 20 2018, In: Immunity. 48, 3, p. 487-499.e5Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
High-Throughput Fitness Profiling of Zika Virus E Protein Reveals Different Roles for Glycosylation during Infection of Mammalian and Mosquito Cells
Gong, D., Zhang, T. H., Zhao, D., Du, Y., Chapa, T. J., Shi, Y., Wang, L., Contreras, D., Zeng, G., Shi, P. Y., Wu, T. T., Arumugaswami, V. & Sun, R., Mar 23 2018, In: iScience. 1, p. 97-111 15 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Highly conserved residues in the helical domain of dengue virus type 1 precursor membrane protein are involved in assembly, precursor membrane (prM) protein cleavage, and entry
Hsieh, S. C., Wu, Y. C., Zou, G., Nerurkar, V. R., Shi, P. Y. & Wang, W. K., Nov 28 2014, In: Journal of Biological Chemistry. 289, 48, p. 33149-33160 12 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Genetic stability of live-attenuated Zika vaccine candidates
Muruato, A. E., Shan, C., Fontes-Garfias, C. R., Liu, Y., Cao, Z., Gao, Q., Weaver, S. C. & Shi, P. Y., Nov 2019, In: Antiviral research. 171, 104596.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Genetic and biochemical characterizations of Zika virus NS2A protein
Zhang, X., Xie, X., Zou, J., Xia, H., Shan, C., Chen, X. & Shi, P. Y., Jan 1 2019, In: Emerging Microbes and Infections. 8, 1, p. 585-602 18 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Generation of a recombinant West Nile virus stably expressing the Gaussia luciferase for neutralization assay
Zhang, P. T., Shan, C., Li, X. D., Liu, S. Q., Deng, C. L., Ye, H. Q., Shang, B. D., Shi, P. Y., Lv, M., Shen, B. F., Qin, C. F. & Zhang, B., Jan 4 2016, In: Virus Research. 211, p. 17-24 8 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Generation and characterization of West Nile pseudo-infectious reporter virus for antiviral screening
Zhang, H. L., Ye, H. Q., Deng, C. L., Liu, S. Q., Shi, P. Y., Qin, C. F., Yuan, Z. M. & Zhang, B., May 1 2017, In: Antiviral research. 141, p. 38-47 10 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Generation and characterization of mouse monoclonal antibodies against NS4B protein of dengue virus
Xie, X., Zou, J., Wang, Q. Y., Noble, C. G., Lescar, J. & Shi, P. Y., Feb 1 2014, In: Virology. 450-451, p. 250-257 8 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Functional analysis of two cavities in flavivirus NS5 polymerase
Zou, G., Chen, Y. L., Dong, H., Lim, C. C., Yap, L. J., Yau, Y. H., Shochat, S. G., Lescar, J. & Shi, P. Y., Apr 22 2011, In: Journal of Biological Chemistry. 286, 16, p. 14362-14372 11 p.Research output: Contribution to journal › Article › peer-review
84 Scopus citations -
Functional Analysis of Glycosylation of Zika Virus Envelope Protein
Fontes-Garfias, C. R., Shan, C., Luo, H., Muruato, A. E., Medeiros, D. B. A., Mays, E., Xie, X., Zou, J., Roundy, C. M., Wakamiya, M., Rossi, S. L., Wang, T., Weaver, S. C. & Shi, P. Y., Oct 31 2017, In: Cell Reports. 21, 5, p. 1180-1190 11 p.Research output: Contribution to journal › Article › peer-review
58 Scopus citations -
Fragile X mental retardation protein is a zika virus restriction factor that is antagonized by subgenomic flaviviral RNA
Soto-Acosta, R., Xie, X., Shan, C., Baker, C. K., Shi, P. Y., Rossi, S. L., Garcia-Blanco, M. A. & Bradrick, S., Dec 1 2018, In: eLife. 7, e39023.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Flavivirus RNA methylation
Dong, H., Fink, K., Züst, R., Lim, S. P., Qin, C. F. & Shi, P. Y., 2014, In: Journal of General Virology. 95, PART 4, p. 763-778 16 p.Research output: Contribution to journal › Review article › peer-review
66 Scopus citations -
Flavivirus NS5 prevents the InSTATement of IFN
Shi, P. Y., Sep 10 2014, In: Cell Host and Microbe. 16, 3, p. 269-271 3 p.Research output: Contribution to journal › Short survey › peer-review
10 Scopus citations -
Flavivirus Entry Inhibitors
Wang, Q. Y. & Shi, P-Y., Jan 8 2016, In: ACS Infectious Diseases. 1, 9, p. 428-434 7 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes
Liu, Y., Liu, J., Du, S., Shan, C., Nie, K., Zhang, R., Li, X. F., Zhang, R., Wang, T., Qin, C. F., Wang, P., Shi, P. Y. & Cheng, G., May 25 2017, In: Nature. 545, 7655, p. 482-486 5 p.Research output: Contribution to journal › Article › peer-review
189 Scopus citations -
Evasion of Type I Interferon by SARS-CoV-2
Xia, H., Cao, Z., Xie, X., Zhang, X., Chen, J. Y. C., Wang, H., Menachery, V. D., Rajsbaum, R. & Shi, P. Y., Oct 6 2020, In: Cell Reports. 33, 1, 108234.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Evasion of early innate immune response by 2′-O-methylation of dengue genomic RNA
Chang, D. C., Hoang, L. T., Mohamed Naim, A. N., Dong, H., Schreiber, M. J., Hibberd, M. L., Tan, M. J. A. & Shi, P. Y., Dec 1 2016, In: Virology. 499, p. 259-266 8 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Evaluation of a novel reporter virus neutralization test for serological diagnosis of Zika and Dengue virus infection
Shan, C., Ortiz, D. A., Yang, Y., Wong, S. J., Kramer, L. D., Shi, P. Y., Loeffelholz, M. J. & Ren, P., Oct 2017, In: Journal of Clinical Microbiology. 55, 10, p. 3028-3036 9 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Erratum to: Targeting vesicle size (Nature Materials, (2018), 17, 11, (955-956), 10.1038/s41563-018-0200-8)
Fei, Z. & Shi, P. Y., Dec 1 2018, In: Nature Materials. 17, 12, p. 1164 1 p.Research output: Contribution to journal › Comment/debate › peer-review
-
Erratum: Zika virus has oncolytic activity against glioblastoma stem cells [The Journal of Experimental Medicine, 214, 10, (2017)] DOI: 10.1084/jem.20171093
Zhu, Z., Gorman, M. J., McKenzie, L. D., Chai, J. N., Hubert, C. G., Prager, B. C., Fernandez, E., Richner, J. M., Zhang, R., Shan, C., Tycksen, E., Wang, X., Shi, P. Y., Diamond, M. S., Rich, J. N. & Chheda, M. G., 2017, In: Journal of Experimental Medicine. 214, 10, p. 3145 1 p.Research output: Contribution to journal › Comment/debate › peer-review
6 Scopus citations -
Erratum: Treatment of human glioblastoma with a live attenuated zika virus vaccine candidate (mBio, (2018) 9(5), e01683-18, 10.1128/mBio.01683-18)
Chen, Q., Wu, J., Ye, Q., Ma, F., Zhu, Q., Wu, Y., Shan, C., Xie, X., Li, D., Zhan, X., Li, C., Li, X. F., Qin, X., Zhao, T., Wu, H., Shi, P. Y., Man, J. & Qin, C. F., Mar 1 2019, In: mBio. 10, 2, e00433-19.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Envelope protein ubiquitination drives entry and pathogenesis of Zika virus
Giraldo, M. I., Xia, H., Aguilera-Aguirre, L., Hage, A., van Tol, S., Shan, C., Xie, X., Sturdevant, G. L., Robertson, S. J., McNally, K. L., Meade-White, K., Azar, S. R., Rossi, S. L., Maury, W., Woodson, M., Ramage, H., Johnson, J. R., Krogan, N. J., Morais, M. C., Best, S. M. & 2 others, , Sep 17 2020, In: Nature. 585, 7825, p. 414-419 6 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Enterovirus 71 VPg uridylation uses a two-molecular mechanism of 3D polymerase
Sun, Y., Wang, Y., Shan, C., Chen, C., Xu, P., Song, M., Zhou, H., Yang, C., Xu, W., Shi, P. Y., Zhang, B. & Lou, Z., Dec 2012, In: Journal of virology. 86, 24, p. 13662-13671 10 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Dysregulation of Ephrin receptor and PPAR signaling pathways in neural progenitor cells infected by Zika virus
Thulasi Raman, S. N., Latreille, E., Gao, J., Zhang, W., Wu, J., Russell, M. S., Walrond, L., Cyr, T., Lavoie, J. R., Safronetz, D., Cao, J., Sauve, S., Farnsworth, A., Chen, W., Shi, P. Y., Wang, Y., Wang, L., Rosu-Myles, M. & Li, X., Jan 1 2020, In: Emerging Microbes and Infections. 9, 1, p. 2046-2060 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery of potent non-nucleoside inhibitors of dengue viral RNA-dependent rna polymerase from fragment screening and structure-guided design
Lim, S. P., Noble, C. G., Nilar, S., Shi, P. Y. & Yokokawa, F., 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 187-198 12 p. (Advances in Experimental Medicine and Biology; vol. 1062).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design
Yokokawa, F., Nilar, S., Noble, C. G., Lim, S. P., Rao, R., Tania, S., Wang, G., Lee, G., Hunziker, J., Karuna, R., Manjunatha, U., Shi, P-Y. & Smith, P. W., Apr 28 2016, In: Journal of Medicinal Chemistry. 59, 8, p. 3935-3952 18 p.Research output: Contribution to journal › Article › peer-review
46 Scopus citations -
Dimerization of flavivirus NS4B protein
Zou, J., Xie, X., Lee, L. T., Chandrasekaran, R., Reynaud, A., Yap, L., Wang, Q. Y., Dong, H., Kang, C., Yuan, Z., Lescar, J. & Shi, P. Y., Mar 2014, In: Journal of virology. 88, 6, p. 3379-3391 13 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Difficulties and advancements in developing drugs for the treatment of dengue fever
Noble, C. G. & Shi, P. Y., Jan 1 2013, In: Expert Opinion on Orphan Drugs. 1, 12, p. 947-949 3 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Did Zika Virus Mutate to Cause Severe Outbreaks?
Rossi, S. L., Ebel, G. D., Shan, C., Shi, P. Y. & Vasilakis, N., Oct 2018, In: Trends in Microbiology. 26, 10, p. 877-885 9 p.Research output: Contribution to journal › Review article › peer-review
11 Scopus citations -
Development of a FACS-based assay for evaluating antiviral potency of compound in dengue infected peripheral blood mononuclear cells
Fu, Y., Chen, Y. L., Herve, M., Gu, F., Shi, P. Y. & Blasco, F., Feb 2014, In: Journal of Virological Methods. 196, p. 18-24 7 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone
Li, X. F., Dong, H. L., Wang, H. J., Huang, X. Y., Qiu, Y. F., Ji, X., Ye, Q., Li, C., Liu, Y., Deng, Y. Q., Jiang, T., Cheng, G., Zhang, F. C., Davidson, A. D., Song, Y. J., Shi, P. Y. & Qin, C. F., Dec 1 2018, In: Nature communications. 9, 1, 673.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
Development and characterization of a stable luciferase dengue virus for high-throughput screening
Zou, G., Xu, H. Y., Qing, M., Wang, Q. Y. & Shi, P. Y., Jul 1 2011, In: Antiviral research. 91, 1, p. 11-19 9 p.Research output: Contribution to journal › Article › peer-review
83 Scopus citations -
Development and characterization of a stable eGFP enterovirus 71 for antiviral screening
Shang, B., Deng, C., Ye, H., Xu, W., Yuan, Z., Shi, P. Y. & Zhang, B., Feb 2013, In: Antiviral research. 97, 2, p. 198-205 8 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Detection and quantification of flavivirus NS5 methyl-transferase activities
Lim, S. P., Bodenreider, C. & Shi, P. Y., Jul 18 2013, Antiviral Methods and Protocols. p. 249-268 20 p. (Methods in Molecular Biology; vol. 1030).Research output: Chapter in Book/Report/Conference proceeding › Chapter
5 Scopus citations -
Design, synthesis and biological evaluation of spiropyrazolopyridone derivatives as potent dengue virus inhibitors
Xu, J., Xie, X., Chen, H., Zou, J., Xue, Y., Ye, N., Shi, P. Y. & Zhou, J., Jun 1 2020, In: Bioorganic and Medicinal Chemistry Letters. 30, 11, 127162.Research output: Contribution to journal › Article › peer-review
-
Design, Synthesis, and Biological Evaluation of Substituted 4,6-Dihydrospiro[[1,2,3]triazolo[4,5- b]pyridine-7,3′-indoline]-2′,5(3 H)-dione Analogues as Potent NS4B Inhibitors for the Treatment of Dengue Virus Infection
Xu, J., Xie, X., Ye, N., Zou, J., Chen, H., White, M. A., Shi, P. Y. & Zhou, J., Sep 12 2019, In: Journal of medicinal chemistry. 62, 17, p. 7941-7960 20 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Dengue Therapeutics, Chemoprophylaxis, and Allied Tools: State of the Art and Future Directions
Whitehorn, J., Yacoub, S., Anders, K. L., Macareo, L. R., Cassetti, M. C., Nguyen Van, V. C., Shi, P. Y., Wills, B. & Simmons, C. P., Aug 28 2014, In: PLoS neglected tropical diseases. 8, 8, e3025.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission
Pompon, J., Manuel, M., Ng, G. K., Wong, B., Shan, C., Manokaran, G., Soto-Acosta, R., Bradrick, S. S., Ooi, E. E., Missé, D., Shi, P. Y. & Garcia-Blanco, M. A., Jul 2017, In: PLoS pathogens. 13, 7, e1006535.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Dengue NS2A Protein Orchestrates Virus Assembly
Xie, X., Zou, J., Zhang, X., Zhou, Y., Routh, A. L., Kang, C., Popov, V. L., Chen, X., Wang, Q. Y., Dong, H. & Shi, P. Y., Nov 13 2019, In: Cell Host and Microbe. 26, 5, p. 606-622.e8Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Dengue in China: not a passing problem
Qin, C. F. & Shi, P. Y., Dec 11 2014, In: Science China Life Sciences. 57, 12, p. 1230-1231 2 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Dengue drug discovery
Shi, P. Y., Yin, Z., Nilar, S. & Keller, T. H., Oct 31 2011, Third World Diseases. Elliot, R. (ed.). p. 243-276 34 p. (Topics in Medicinal Chemistry; vol. 7).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: Implication for a trans mechanism of VPg uridylylation
Chen, C., Wang, Y., Shan, C., Sun, Y., Xu, P., Zhou, H., Yang, C., Shi, P. Y., Rao, Z., Zhang, B. & Lou, Z., May 1 2013, In: Journal of virology. 87, 10, p. 5755-5768 14 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
Crystal structure of dengue virus methyltransferase without S-adenosyl-L-methionine
Noble, C. G., Li, S. H., Dong, H., Chew, S. H. & Shi, P. Y., Nov 2014, In: Antiviral research. 111, p. 78-81 4 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses
Sahin, U., Muik, A., Derhovanessian, E., Vogler, I., Kranz, L. M., Vormehr, M., Baum, A., Pascal, K., Quandt, J., Maurus, D., Brachtendorf, S., Lörks, V., Sikorski, J., Hilker, R., Becker, D., Eller, A. K., Grützner, J., Boesler, C., Rosenbaum, C., Kühnle, M. C. & 22 others, , Oct 22 2020, In: Nature. 586, 7830, p. 594-599 6 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
Corrigendum to "Population variation of West Nile virus confers a host-specific fitness benefit in mosquitoes" [Virology 404 (2010) 89-95]
Fitzpatrick, K. A., Deardorff, E. R., Pesko, K., Brackney, D. E., Zhang, B., Bedrick, E., Shi, P. Y. & Ebel, G. D., Feb 20 2011, In: Virology. 410, 2, p. 437 1 p.Research output: Contribution to journal › Comment/debate › peer-review
-
Construction of stable reporter flaviviruses and their applications
Baker, C. & Shi, P. Y., Oct 2020, In: Viruses. 12, 10, 1082.Research output: Contribution to journal › Article › peer-review
Open Access -
Conformational flexibility of the dengue virus RNA-Dependent RNA polymerase revealed by a complex with an inhibitor
Noble, C. G., Lim, S. P., Chen, Y. L., Liew, C. W., Yap, L., Lescar, J. & Shi, P. Y., May 2013, In: Journal of virology. 87, 9, p. 5291-5295 5 p.Research output: Contribution to journal › Article › peer-review
70 Scopus citations