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• Zika Virus Vaccine: Progress and Challenges

  Shan, C., Xie, X. & Shi, P. Y., Jul 11 2018, In: Cell Host and Microbe. 24, 1, p. 12-17 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus
  • Vaccines
  • Eye Abnormalities
  • Flavivirus
  • Explosive Agents
  36 Scopus citations

• Zika virus infection elicits auto-antibodies to C1q

  Koma, T., Veljkovic, V., Anderson, D. E., Wang, L. F., Rossi, S. L., Shan, C., Shi, P. Y., Beasley, D. W., Bukreyeva, N., Smith, J. N., Hallam, S., Huang, C., Von Messling, V. & Paessler, S., Dec 1 2018, In: Scientific reports. 8, 1, 1882.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus Infection
  • Zika Virus
  • Antibodies
  • Complement C1q
  • Viral Structures
  10 Scopus citations

• Zika structural genes determine the virulence of African and Asian lineages

  Nunes, B. T. D., Fontes-Garfias, C. R., Shan, C., Muruato, A. E., Nunes, J. G. C., Burbano, R. M. R., Vasconcelos, P. F. C., Shi, P. Y. & Medeiros, D. B. A., Jan 1 2020, In: Emerging Microbes and Infections. 9, 1, p. 1023-1033 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus
  • Virulence
  • Viruses
  • Epidemics
  • Genes

• West nile virus experimental evolution in vivo and the trade-off hypothesis

  Deardorff, E. R., Fitzpatrick, K. A., Jerzak, G. V. S., Shi, P. Y., Kramer, L. D. & Ebel, G. D., Nov 2011, In: PLoS pathogens. 7, 11, e1002335.

  Research output: Contribution to journal › Article › peer-review

  • West Nile virus
  • Viruses
  • Culicidae
  • Culex
  • Birds
  70 Scopus citations

• West Nile virus drug discovery

  Lim, S. P. & Shi, P. Y., Dec 3 2013, In: Viruses. 5, 12, p. 2977-3006 30 p.

  Research output: Contribution to journal › Review article › peer-review

  • West Nile virus
  • Drug Discovery
  • Antiviral Agents
  • Antibodies
  • Flaviviridae
  27 Scopus citations

• Vesicular stomatitis virus and DNA vaccines expressing zika virus nonstructural protein 1 induce substantial but not sterilizing protection against zika virus infection

  Li, A., Xue, M., Attia, Z., Yu, J., Lu, M., Shan, C., Liang, X., Gao, T. Z., Shi, P. Y., Peeples, M. E., Boyaka, P. N., Liu, S. L. & Li, J., Sep 2020, In: Journal of virology. 94, 17, e00048-20.

  Research output: Contribution to journal › Article › peer-review

  • Zika virus
  • Zika Virus Infection
  • Zika Virus
  • recombinant vaccines
  • Vesiculovirus

• Using recombination-dependent lethal mutations to stabilize reporter flaviviruses for rapid serodiagnosis and drug discovery

  Baker, C., Xie, X., Zou, J., Muruato, A., Fink, K. & Shi, P. Y., Jul 2020, In: EBioMedicine. 57, 102838.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Drug Discovery
  • Flavivirus
  • Viruses
  • Serologic Tests
  • Genetic Recombination
  4 Scopus citations

• Using next generation sequencing to study the genetic diversity of candidate live attenuated zika vaccines

  Collins, N. D., Shan, C., Nunes, B. T. D., Widen, S. G., Shi, P. Y., Barrett, A. D. T. & Sarathy, V. V., Apr 2020, In: Vaccines. 8, 2, 161.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus
  • Attenuated Vaccines
  • Genetic Variation
  • Membranes
  • Flaviviridae
  2 Scopus citations

• Using a virion assembly-defective dengue virus as a vaccine approach

  Shan, C., Xie, X., Zou, J., Züst, R., Zhang, B., Ambrose, R., Mackenzie, J., Fink, K. & Shi, P. Y., Nov 1 2018, In: Journal of virology. 92, 21, e01002.

  Research output: Contribution to journal › Article › peer-review

  • Defective Viruses
  • Dengue virus
  • Dengue Virus
  • virion
  • Virion
  10 Scopus citations

• Unraveling a flavivirus enigma

  Shi, P. Y., Jan 1 2014, In: Science. 343, 6173, p. 849-850 2 p.

  Research output: Contribution to journal › Short survey › peer-review

  • Flavivirus
  • Proteins
  9 Scopus citations

• U18666A, an intra-cellular cholesterol transport inhibitor, inhibits dengue virus entry and replication

  Poh, M. K., Shui, G., Xie, X., Shi, P. Y., Wenk, M. R. & Gu, F., Jan 2012, In: Antiviral research. 93, 1, p. 191-198 8 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one
  • Anticholesteremic Agents
  • Virus Internalization
  • Dengue Virus
  • Virus Replication
  72 Scopus citations

• Type I interferon signals in macrophages and dendritic cells control dengue virus infection: Implications for a new mouse model to test dengue vaccines

  Züst, R., Toh, Y. X., Valdés, I., Cerny, D., Heinrich, J., Hermida, L., Marcos, E., Guillén, G., Kalinke, U., Shi, P. Y. & Fink, K., 2014, In: Journal of virology. 88, 13, p. 7276-7285 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Vaccines
  • Dengue virus
  • dendritic cells
  • dengue
  • Interferon Type I
  52 Scopus citations

• Type I and Type III interferons restrict SARS-CoV-2 infection of human airway epithelial cultures

  Vanderheiden, A., Ralfs, P., Chirkova, T., Upadhyay, A. A., Zimmerman, M. G., Bedoya, S., Aoued, H., Tharp, G. M., Pellegrini, K. L., Manfredi, C., Sorscher, E., Mainou, B., Lobby, J. L., Kohlmeier, J. E., Lowen, A. C., Shi, P. Y., Menachery, V. D., Anderson, L. J., Grakoui, A., Bosinger, S. E. & 1 others, Suthar, M. S., Oct 2020, In: Journal of virology. 94, 19, e00985-20.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Severe acute respiratory syndrome coronavirus
  • interferon type III
  • Coronavirus Infections
  • Severe Acute Respiratory Syndrome
  • interferons
  19 Scopus citations

• Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies

  Arora, R., Liew, C. W., Soh, T. S., Otoo, D. A., Seh, C. C., Yue, K., Nilar, S., Wang, G., Yokokawa, F., Noble, C. G., Chen, Y. L., Shi, P. Y., Lescar, J., Smith, T. M., Benson, T. E. & Lim, S. P., Dec 2020, In: Journal of virology. 94, 24, e01130-20.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Dengue Virus
  • RNA Replicase
  • RNA-directed RNA polymerase
  • RNA

• Treatment of human glioblastoma with a live attenuated Zika virus vaccine candidate

  Chen, Q., Wu, J., Ye, Q., Ma, F., Zhu, Q., Wu, Y., Shan, C., Xie, X., Li, D., Zhan, X., Li, C., Li, X. F., Qin, X., Zhao, T., Wu, H., Shi, P. Y., Man, J. & Qin, C. F., Sep 1 2018, In: mBio. 9, 5, e01683-18.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Glioblastoma
  • Vaccines
  • Glioma
  • Stem Cells
  32 Scopus citations

• Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses

  Prasanth, K. R., Hirano, M., Fagg, W. S., McAnarney, E. T., Shan, C., Xie, X., Hage, A., Pietzsch, C. A., Bukreyev, A., Rajsbaum, R., Shi, P. Y., Bedford, M. T., Bradrick, S. S., Menachery, V. & Garcia-Blanco, M. A., Oct 2020, In: Antiviral research. 182, 104874.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA topoisomerase III
  • Yellow fever virus
  • SARS Virus
  • Dengue Virus
  • RNA Viruses
  3 Scopus citations

• The structural basis for serotype-specific neutralization of dengue virus by a human antibody

  Teoh, E. P., Kukkaro, P., Teo, E. W., Lim, A. P. C., Tan, T. T., Yip, A., Schul, W., Aung, M., Kostyuchenko, V. A., Leo, Y. S., Chan, S. H., Smith, K. G. C., Chan, A. H. Y., Zou, G., Ooi, E. E., Kemeny, D. M., Tan, G. K., Ng, J. K. W., Ng, M. L., Alonso, S. & 5 others, Fisher, D., Shi, P. Y., Hanson, B. J., Lok, S. M. & MacAry, P. A., Jun 20 2012, In: Science Translational Medicine. 4, 139, 139ra83.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Serogroup
  • Antibodies
  • Immunity
  • Cryoelectron Microscopy
  165 Scopus citations

• The stem region of premembrane protein plays an important role in the virus surface protein rearrangement during dengue maturation

  Zhang, Q., Hunke, C., Yau, Y. H., Seow, V., Lee, S., Tanner, L. B., Guan, X. L., Wenk, M. R., Fibriansah, G., Chew, P. L., Kukkaro, P., Biuković, G., Shi, P. Y., Shochat, S. G., Grüber, G. & Lok, S. M., Nov 23 2012, In: Journal of Biological Chemistry. 287, 48, p. 40525-40534 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Viruses
  • Dengue
  • Membrane Proteins
  • Exosomes
  • Dengue Virus
  32 Scopus citations

• Therapeutics for Dengue: Recommendations for Design and Conduct of Early-Phase Clinical Trials

  Simmons, C. P., Wolbers, M., Nguyen, M. N., Whitehorn, J., Shi, P. Y., Young, P., Petric, R., Nguyen, V. V. C., Farrar, J. & Wills, B., Sep 2012, In: PLoS neglected tropical diseases. 6, 9, e1752.

  Research output: Contribution to journal › Article › peer-review
  25 Scopus citations

• The Interface between Methyltransferase and Polymerase of NS5 Is Essential for Flavivirus Replication

  Li, X. D., Shan, C., Deng, C. L., Ye, H. Q., Shi, P. Y., Yuan, Z. M., Gong, P. & Zhang, B., May 2014, In: PLoS neglected tropical diseases. 8, 5, e2891.

  Research output: Contribution to journal › Article › peer-review

  • RNA Replicase
  • Flavivirus
  • Methyltransferases
  • Japanese Encephalitis Virus
  • Reverse Genetics
  28 Scopus citations

• The helical domains of the stem region of dengue virus envelope protein are involved in both virus assembly and entry

  Lin, S. R., Zou, G., Hsieh, S. C., Qing, M., Tsai, W. Y., Shi, P. Y. & Wang, W. K., May 2011, In: Journal of virology. 85, 10, p. 5159-5171 13 p.

  Research output: Contribution to journal › Article › peer-review

  • virus assembly
  • Viral Envelope Proteins
  • Dengue virus
  • Virus Assembly
  • Virus Internalization
  34 Scopus citations

• The C-terminal helical domain of dengue virus precursor membrane protein is involved in virus assembly and entry

  Hsieh, S. C., Zou, G., Tsai, W. Y., Qing, M., Chang, G. J., Shi, P. Y. & Wang, W. K., Feb 5 2011, In: Virology. 410, 1, p. 170-180 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Virus Assembly
  • Virus Internalization
  • Dengue Virus
  • Membrane Proteins
  • Mutation
  26 Scopus citations

• The 5′ and 3′ downstream AUG region elements are required for mosquito-borne flavivirus RNA replication

  Friebe, P., Shi, P. Y. & Harris, E., Feb 2011, In: Journal of virology. 85, 4, p. 1900-1905 6 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA replication
  • Flavivirus
  • Flaviviridae
  • Culicidae
  • Viral RNA
  54 Scopus citations

• Testing Antiviral Compounds in a Dengue Mouse Model

  Schul, W., Yip, A. & Shi, P. Y., Jul 18 2013, Antiviral Methods and Protocols. p. 269-281 13 p. (Methods in Molecular Biology; vol. 1030).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Dengue Virus
  • Dengue
  • Antiviral Agents
  • Virus Diseases
  • Active Immunotherapy
  3 Scopus citations

• Ten years of dengue drug discovery: Progress and prospects

  Lim, S. P., Wang, Q. Y., Noble, C. G., Chen, Y. L., Dong, H., Zou, B., Yokokawa, F., Nilar, S., Smith, P., Beer, D., Lescar, J. & Shi, P. Y., 2013, In: Antiviral research. 100, 2, p. 500-519 20 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue Virus
  • Dengue
  • Drug Discovery
  • balapiravir
  • celgosivir
  241 Scopus citations

• Targeting vesicle size

  Zou, J. & Shi, P. Y., Nov 1 2018, In: Nature Materials. 17, 11, p. 955-956 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • blood-brain barrier
  • Peptides
  • viruses
  • Viruses
  • peptides

• Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides

  Tichý, M., Pohl, R., Xu, H. Y., Chen, Y. L., Yokokawa, F., Shi, P. Y. & Hocek, M., Oct 15 2012, In: Bioorganic and Medicinal Chemistry. 20, 20, p. 6123-6133 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Ribonucleosides
  • indole
  • Antiviral Agents
  • stannane
  • Cross Reactions
  37 Scopus citations

• Structure-activity relationship of uridine-based nucleoside phosphoramidate prodrugs for inhibition of dengue virus RNA-dependent RNA polymerase

  Wang, G., Lim, S. P., Chen, Y. L., Hunziker, J., Rao, R., Gu, F., Seh, C. C., Ghafar, N. A., Xu, H., Chan, K., Lin, X., Saunders, O. L., Fenaux, M., Zhong, W., Shi, P. Y. & Yokokawa, F., Jul 15 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 13, p. 2324-2327 4 p.

  Research output: Contribution to journal › Article › peer-review

  • phosphoramidic acid
  • RNA Replicase
  • Uridine
  • Dengue Virus
  • Structure-Activity Relationship
  8 Scopus citations

• Structural biology of dengue virus enzymes: Towards rational design of therapeutics

  Noble, C. G. & Shi, P. Y., Nov 1 2012, In: Antiviral research. 96, 2, p. 115-126 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue Virus
  • Methyltransferases
  • Dengue
  • Enzymes
  • Peptide Hydrolases
  78 Scopus citations
• • SARS Virus
  • Viral Vaccines
  • Mutation
  • Cricetinae
  • Viruses
  35 Scopus citations

• Spike mutation D614G alters SARS-CoV-2 fitness

  Plante, J. A., Liu, Y., Liu, J., Xia, H., Johnson, B. A., Lokugamage, K. G., Zhang, X., Muruato, A. E., Zou, J., Fontes-Garfias, C. R., Mirchandani, D., Scharton, D., Bilello, J. P., Ku, Z., An, Z., Kalveram, B., Freiberg, A. N., Menachery, V. D., Xie, X., Plante, K. S. & 2 others, Weaver, S. C. & Shi, P. Y., 2020, (Accepted/In press) In: Nature.

  Research output: Contribution to journal › Article › peer-review

  • SARS Virus
  • Viral Vaccines
  • Mutation
  • Cricetinae
  • Viruses
  35 Scopus citations

• Small molecule inhibitors that selectively block dengue virus methyltransferase

  Lim, S. P., Sonntag, L. S., Noble, C., Nilar, S. H., Ng, R. H., Zou, G., Monaghan, P., Chung, K. Y., Dong, H., Liu, B., Bodenreider, C., Lee, G., Ding, M., Chan, W. L., Wang, G., Jian, Y. L., Chao, A. T., Lescar, J., Yin, Z., Vedananda, T. R. & 2 others, Keller, T. H. & Shi, P. Y., Feb 25 2011, In: Journal of Biological Chemistry. 286, 8, p. 6233-6240 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Viruses
  • Methyltransferases
  • Molecules
  • Flavivirus
  108 Scopus citations

• Short Direct Repeats in the 3' Untranslated Region Are Involved in Subgenomic Flaviviral RNA Production

  Zhang, Q. Y., Li, X. F., Niu, X., Li, N., Wang, H. J., Deng, C. L., Ye, H. Q., Huang, X. Y., Chen, Q., Xu, Y. P., Dong, H. L., Li, X. D., Zhao, H., Shi, P. Y., Yuan, Z. M., Gong, P., Fang, X., Qin, C. F. & Zhang, B., Feb 28 2020, In: Journal of virology. 94, 6

  Research output: Contribution to journal › Article › peer-review

  • Nucleic Acid Repetitive Sequences
  • 3' untranslated regions
  • 3' Untranslated Regions
  • RNA
  • Flavivirus
  3 Scopus citations

• Safety and immunogenicity of two RNA-based covid-19 vaccine candidates

  Walsh, E. E., Frenck, R. W., Falsey, A. R., Kitchin, N., Absalon, J., Gurtman, A., Lockhart, S., Neuzil, K., Mulligan, M. J., Bailey, R., Swanson, K. A., Li, P., Koury, K., Kalina, W., Cooper, D., Fontes-Garfias, C., Shi, P. Y., Türeci, Ö., Tompkins, K. R., Lyke, K. E. & 5 others, Raabe, V., Dormitzer, P. R., Jansen, K. U., Şahin, U. & Gruber, W. C., Dec 17 2020, In: New England Journal of Medicine. 383, 25, p. 2439-2450 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vaccines
  • Severe Acute Respiratory Syndrome
  • RNA
  • Safety
  • Coronavirus
  73 Scopus citations

• Role of microglia in the dissemination of zika virus from mother to fetal brain

  Xu, P., Shan, C., Dunn, T. J., Xie, X., Xia, H., Gao, J., Labastida, J. A., Zou, J., Villarreal, P. P., Schlagal, C. R., Yu, Y., Vargas, G., Rossi, S. L., Vasilakis, N., Shi, P. Y., Weaver, S. C. & Wu, P., Jul 2020, In: PLoS neglected tropical diseases. 14, 7, p. 1-21 21 p., e0008413.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus
  • Yolk Sac
  • Microglia
  • Zika Virus Infection
  • Microcephaly
  2 Scopus citations

• Resistance analysis of an antibody that selectively inhibits dengue virus serotype-1

  Zou, G., Kukkaro, P., Lok, S. M., Ng, J. K. W., Tan, G. K., Hanson, B. J., Alonso, S., MacAry, P. A. & Shi, P. Y., Sep 1 2012, In: Antiviral research. 95, 3, p. 216-223 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Serogroup
  • Antibodies
  • Viral Envelope Proteins
  • Viruses
  11 Scopus citations

• Reserve genetic approaches for the development of Zika vaccines and therapeutics

  Fontes-Garfias, C. R., Baker, C. K. & Shi, P. Y., Oct 2020, In: Current Opinion in Virology. 44, p. 7-15 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus
  • Vaccines
  • Reverse Genetics
  • Epidemics
  • Antiviral Agents
  2 Scopus citations

• Report of the fifth symposium on emerging viral diseases

  Zhang, B. & Shi, P. Y., Apr 2013, In: Virologica Sinica. 28, 2, p. 63-64 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• Recovery of a chemically synthesized Japanese encephalitis virus reveals two critical adaptive mutations in NS2B and NS4A

  Li, X. D., Li, X. F., Ye, H. Q., Deng, C. L., Ye, Q., Shan, C., Shang, B. D., Xu, L. L., Li, S. H., Cao, S. B., Yuan, Z. M., Shi, P. Y., Qin, C. F. & Zhang, B., 2014, In: Journal of General Virology. 95, PART 4, p. 806-815 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Japanese Encephalitis Virus
  • Mutation
  • Viruses
  • Clone Cells
  • Nucleic Acid Databases
  27 Scopus citations

• Rational Design of a Live Attenuated Dengue Vaccine: 2′-O-Methyltransferase Mutants Are Highly Attenuated and Immunogenic in Mice and Macaques

  Züst, R., Dong, H., Li, X. F., Chang, D. C., Zhang, B., Balakrishnan, T., Toh, Y. X., Jiang, T., Li, S. H., Deng, Y. Q., Ellis, B. R., Ellis, E. M., Poidinger, M., Zolezzi, F., Qin, C. F., Shi, P. Y. & Fink, K., Aug 2013, In: PLoS pathogens. 9, 8, e1003521.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Vaccines
  • Attenuated Vaccines
  • Methyltransferases
  • Macaca
  • Viruses
  79 Scopus citations

• Rational design of a flavivirus vaccine by abolishing viral RNA 2′-O methylation

  Li, S. H., Dong, H., Li, X. F., Xie, X., Zhao, H., Deng, Y. Q., Wang, X. Y., Ye, Q., Zhu, S. Y., Wang, H. J., Zhang, B., Leng, Q. B., Zuest, R., Qin, E. D., Qin, C. F. & Shi, P. Y., May 2013, In: Journal of virology. 87, 10, p. 5812-5819 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Flavivirus
  • Viral RNA
  • methylation
  • Methylation
  • vaccines
  67 Scopus citations

• Quantitative SARS-CoV-2 Serology in Children With Multisystem Inflammatory Syndrome (MIS-C)

  Rostad, C. A., Chahroudi, A., Mantus, G., Lapp, S. A., Teherani, M., Macoy, L., Tarquinio, K. M., Basu, R. K., Kao, C., Linam, W. M., Zimmerman, M. G., Shi, P-Y., Menachery, V. D., Oster, M. E., Edupuganti, S., Anderson, E. J., Suthar, M. S., Wrammert, J. & Jaggi, P., Dec 1 2020, In: Pediatrics. 146, 6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Serology
  • Child
  • Immunoglobulin G

• Potential Mechanisms for Enhanced Zika Epidemic and Disease

  Xia, H., Xie, X., Shan, C. & Shi, P. Y., May 11 2018, In: ACS Infectious Diseases. 4, 5, p. 656-659 4 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus Infection
  • Epidemics
  • Herd Immunity
  • Flavivirus
  • Mutation
  5 Scopus citations

• Polymerases of hepatitis C viruses and flaviviruses: Structural and mechanistic insights and drug development

  Caillet-Saguy, C., Lim, S. P., Shi, P. Y., Lescar, J. & Bressanelli, S., May 2014, In: Antiviral research. 105, 1, p. 8-16 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Flavivirus
  • Flaviviridae
  • Drug Development
  • Hepacivirus
  • Polyproteins
  38 Scopus citations

• Point mutations in the West Nile virus (Flaviviridae; Flavivirus) RNA-dependent RNA polymerase alter viral fitness in a host-dependent manner in vitro and in vivo

  Van Slyke, G. A., Ciota, A. T., Willsey, G. G., Jaeger, J., Shi, P. Y. & Kramer, L. D., May 25 2012, In: Virology. 427, 1, p. 18-24 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Flaviviridae
  • RNA Replicase
  • West Nile virus
  • Flavivirus
  • Point Mutation
  21 Scopus citations

• Peli1 signaling blockade attenuates congenital zika syndrome

  Luo, H., Li, G., Wang, B., Tian, B., Gao, J., Zou, J., Shi, S., Zhu, S., Peng, B. H., Adam, A., Martinez, A., Hein, K., Winkelmann, E. R., Mahmoud, Y., Zhou, X., Shan, C., Rossi, S., Weaver, S., Barrett, A. D. T., Sun, S. C. & 4 others, Zhang, W., Shi, P. Y., Wu, P. & Wang, T., Jun 2020, In: PLoS pathogens. 16, 6, e1008538.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus
  • Trophoblasts
  • Flavivirus
  • Cell Death
  • Zika Virus Infection
  1 Scopus citations

• Peli1 facilitates virus replication and promotes neuroinflammation during West Nile virus infection

  Luo, H., Winkelmann, E. R., Zhu, S., Ru, W., Mays, E., Silvas, J. A., Vollmer, L. L., Gao, J., Peng, B. H., Bopp, N. E., Cromer, C., Shan, C., Xie, G., Li, G., Tesh, R., Popov, V. L., Shi, P. Y., Sun, S. C., Wu, P., Klein, R. S. & 4 others, Tang, S. J., Zhang, W., Aguilar, P. V. & Wang, T., Nov 1 2018, In: Journal of Clinical Investigation. 128, 11, p. 4980-4991 12 p.

  Research output: Contribution to journal › Article › peer-review

  • West Nile Fever
  • West Nile virus
  • Microglia
  • Virus Replication
  • Encephalitis
  11 Scopus citations

• Overlapping and distinct molecular determinants dictating the antiviral activities of TRIM56 against flaviviruses and coronavirus

  Liu, B., Li, N. L., Wang, J., Shi, P. Y., Wang, T., Miller, M. A. & Li, K., 2014, In: Journal of virology. 88, 23, p. 13821-13835 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Flaviviridae
  • Coronavirinae
  • Flavivirus
  • Coronavirus
  • Human Coronavirus OC43
  40 Scopus citations

• NS5 from dengue virus serotype 2 can adopt a conformation analogous to that of its zika virus and Japanese encephalitis virus homologues

  El Sahili, A., Soh, T. S., Schiltz, J., Gharbi-Ayachi, A., Seh, C. C., Shi, P. Y., Lim, S. P. & Lescar, J., Jan 1 2020, In: Journal of virology. 94, 1, e01294-19.

  Research output: Contribution to journal › Article › peer-review

  • Zika virus
  • Japanese encephalitis virus
  • Japanese Encephalitis Virus
  • Zika Virus
  • Dengue virus
  5 Scopus citations

• Noninvasive bioluminescence imaging of dengue virus infection in the brain of A129 mice

  Li, X. F., Deng, Y. Q., Zhao, H., Ye, Q., Wang, H. J., Li, S. H., Zhu, S. Y., Shi, P. Y., Qin, E. D., Zhang, B. & Qin, C. F., May 1 2013, In: Applied Microbiology and Biotechnology. 97, 10, p. 4589-4596 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Virus Diseases
  • Brain
  • Antiviral Agents
  • Renilla Luciferases
  9 Scopus citations