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Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study
For the ADEPT (Airways Disease Endotyping for Personalized Therapeutics) & U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) investigators, Dec 15 2016, In: Respiratory Research. 17, 1, 165.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data
Wu, W., Bleecker, E., Moore, W., Busse, W. W., Castro, M., Chung, K. F., Calhoun, W. J., Erzurum, S., Gaston, B., Israel, E., Curran-Everett, D. & Wenzel, S. E., May 2014, In: Journal of Allergy and Clinical Immunology. 133, 5, p. 1280-1288 9 p.Research output: Contribution to journal › Article › peer-review
149 Scopus citations -
Underuse of guideline-recommended long-term asthma management in children hospitalized to the intensive care unit: A multicenter observational study
Hasegawa, K., Ahn, J., Brown, M. A., Press, V. G., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Aurora, T., Brenner, B., Calhoun, W., Gough, J. E., Gutta, R. C., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S., Nowak, R., Pei, V. & 9 others, , Jul 1 2015, In: Annals of Allergy, Asthma and Immunology. 115, 1, p. 10-16.e1Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
The spectrum of asthma: an introduction.
Calhoun, W. J., 2014, In: Advances in experimental medicine and biology. 795, p. 1-4 4 p.Research output: Contribution to journal › Editorial › peer-review
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The role of computed tomography in chronic obstructive pulmonary diseases
Sze, T. F. C., Ditzler, M. G., Walser, E. M. & Calhoun, W. J., 2015, In: Journal of Allergy and Clinical Immunology: In Practice. 3, 4, p. 594-596 3 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma
Chu, D. K., Al-Garawi, A., Llop-Guevara, A., Pillai, R. A., Radford, K., Shen, P., Walker, T. D., Goncharova, S., Calhoun, W. J., Nair, P. & Jordana, M., Apr 12 2015, In: Allergy, Asthma and Clinical Immunology. 11, 1, 14.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
Symptom-adjusted therapy in asthma: It is time to listen to our patients
Bhat, K. D. & Calhoun, W. J., May 1 2011, In: Expert Review of Clinical Immunology. 7, 3, p. 259-261 3 p.Research output: Contribution to journal › Editorial › peer-review
1 Scopus citations -
Strategies for molecular classification of asthma using bipartite network analysis of cytokine expression
Pillai, R. R., Divekar, R., Brasier, A., Bhavnani, S. & Calhoun, W. J., Oct 1 2012, In: Current Allergy and Asthma Reports. 12, 5, p. 388-395 8 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Sleep quality and asthma control and quality of life in non-severe and severe asthma
Luyster, F. S., Teodorescu, M., Bleecker, E., Busse, W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S., Israel, E., Strollo, P. J. & Wenzel, S. E., Dec 2012, In: Sleep and Breathing. 16, 4, p. 1129-1137 9 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
Sex differences in hospital length of stay in children and adults hospitalized for asthma exacerbation
Hasegawa, K., Calhoun, W. J., Pei, Y. V., Chasm, R. M., Youngquist, S. T., Bittner, J. C. & Camargo, C. A., Dec 1 2015, In: Annals of Allergy, Asthma and Immunology. 115, 6, p. 533-535.e1Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Severe asthma: Lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program
Jarjour, N. N., Erzurum, S. C., Bleecker, E. R., Calhoun, W. J., Castro, M., Comhair, S. A. A., Chung, K. F., Curran-Everett, D., Dweik, R. A., Fain, S. B., Fitzpatrick, A. M., Gaston, B. M., Israel, E., Hastie, A., Hoffman, E. A., Holguin, F., Levy, B. D., Meyers, D. A., Moore, W. C., Peters, S. P. & 4 others, , Feb 15 2012, In: American Journal of Respiratory and Critical Care Medicine. 185, 4, p. 356-362 7 p.Research output: Contribution to journal › Review article › peer-review
169 Scopus citations -
Safety of investigative bronchoscopy in the Severe Asthma Research Program
Moore, W. C., Evans, M. D., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Curran-Everett, D., Dweik, R. A., Gaston, B., Hew, M., Israel, E., Mayse, M. L., Pascual, R. M., Peters, S. P., Silveira, L., Wenzel, S. E. & Jarjour, N. N., Aug 2011, In: Journal of Allergy and Clinical Immunology. 128, 2, p. 328-336.e3Research output: Contribution to journal › Article › peer-review
41 Scopus citations -
Race is associated with differences in airway inflammation in patients with asthma
Nyenhuis, S. M., Krishnan, J. A., Berry, A., Calhoun, W. J., Chinchilli, V. M., Engle, L., Grossman, N., Holguin, F., Israel, E., Kittles, R. A., Kraft, M., Lazarus, S. C., Lehman, E. B., Mauger, D. T., Moy, J. N., Peters, S. P., Phipatanakul, W., Smith, L. J., Sumino, K., Szefler, S. J. & 4 others, , Jul 2017, In: Journal of Allergy and Clinical Immunology. 140, 1, p. 257-265.e11Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
Proteomic insights into inflammatory airway diseases
Brasier, A. R. & Calhoun, W. J., Jul 1 2011, In: Current Proteomics. 8, 2, p. 84-96 13 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
Post-transplant native pneumonectomy for interstitial fibrosis and small cell lung cancer
Li, R. T., Zahedi, S., Trieu, J., Lea, A. S., Calhoun, W. J., Duarte, A. G., Zhao, J. & Okereke, I. C., Dec 1 2017, In: Journal of Thoracic Disease. 9, 12, p. E1096-E1099Research output: Contribution to journal › Article › peer-review
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Outpatient Management of Chronic Asthma in 2020
Tripple, J. W., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 561-562 2 p.Research output: Contribution to journal › Short survey › peer-review
3 Scopus citations -
Omalizumab in asthma: Is the therapeutic window too small?
Bhat, K. D. & Calhoun, W. J., Jan 1 2011, In: Chest. 139, 1, p. 8-10 3 p.Research output: Contribution to journal › Editorial › peer-review
6 Scopus citations -
Obesity's effect on asthma extends to diagnostic criteria
Lugogo, N., Green, C. L., Agada, N., Zhang, S., Meghdadpour, S., Zhou, R., Yang, S., Anstrom, K. J., Israel, E., Martin, R., Lemanske, R. F., Boushey, H., Lazarus, S. C., Wasserman, S. I., Castro, M., Calhoun, W., Peters, S. P., DiMango, E., Chinchilli, V., Kunselman, S. & 3 others, , Mar 2018, In: Journal of Allergy and Clinical Immunology. 141, 3, p. 1096-1104 9 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Obesity and asthma: An association modified by age of asthma onset
Holguin, F., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Yonas, M., Teague, W. G. & Wenzel, S. E., Jun 2011, In: Journal of Allergy and Clinical Immunology. 127, 6, p. 1486-1493.e2Research output: Contribution to journal › Article › peer-review
217 Scopus citations -
National estimates of 30-day readmissions among children hospitalized for asthma in the United States
Veeranki, S., Ohabughiro, M. U., Moran, J., Mehta, H. B., Ameredes, B. T., Kuo, Y. F. & Calhoun, W. J., Jul 3 2018, In: Journal of Asthma. 55, 7, p. 695-704 10 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations
Torgerson, D. G., Ampleford, E. J., Chiu, G. Y., Gauderman, W. J., Gignoux, C. R., Graves, P. E., Himes, B. E., Levin, A. M., Mathias, R. A., Hancock, D. B., Baurley, J. W., Eng, C., Stern, D. A., Celedón, J. C., Rafaels, N., Capurso, D., Conti, D. V., Roth, L. A., Soto-Quiros, M., Togias, A. & 55 others, , Sep 2011, In: Nature Genetics. 43, 9, p. 887-892 6 p.Research output: Contribution to journal › Article › peer-review
528 Scopus citations -
Management of Acute Asthma in Adults in 2020
Zaidan, M. F., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 563-564 2 p.Research output: Contribution to journal › Short survey › peer-review
1 Scopus citations -
Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study
The ADEPT Investigators, 2016, In: Respiratory Research. 17, 1, p. 1-12 12 p., 43.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Key observations from the NHLBI Asthma Clinical Research Network
Szefler, S. J., Chinchilli, V. M., Israel, E., Denlinger, L. C., Lemanske, R. F., Calhoun, W. & Peters, S. P., May 2012, In: Thorax. 67, 5, p. 450-455 6 p.Research output: Contribution to journal › Review article › peer-review
10 Scopus citations -
Introduction to asthma and phenotyping
Pillai, R. A. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
5 Scopus citations -
Introduction to asthma and phenotyping
Pillai, R. A. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Improving Quality of Acute Asthma Care in US Hospitals: Changes Between 1999-2000 and 2012-2013
Hasegawa, K., Tsugawa, Y., Clark, S., Eastin, C. D., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Ahn, J., Aurora, T., Brenner, B., Brown, M. A., Calhoun, W., Gough, J. E., Gharib, A., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S. & 11 others, , Jul 1 2016, In: Chest. 150, 1, p. 112-122 11 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Importance of hedgehog interacting protein and other lung function genes in asthma
Li, X., Howard, T. D., Moore, W. C., Ampleford, E. J., Li, H., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Teague, W. G., Wenzel, S. E., Peters, S. P., Hawkins, G. A., Bleecker, E. R. & Meyers, D. A., Jun 2011, In: Journal of Allergy and Clinical Immunology. 127, 6, p. 1457-1465 9 p.Research output: Contribution to journal › Article › peer-review
92 Scopus citations -
Impact of race on asthma treatment failures in the Asthma Clinical Research Network
Wechsler, M. E., Castro, M., Lehman, E., Chinchilli, V. M., Sutherland, E. R., Denlinger, L., Lazarus, S. C., Peters, S. P., Israel, E., Martin, R. J., Szefler, S. J., Cherniack, R., Lemanske, R. F., Sorkness, C. A., Jarjour, N., Craig, T., Kunselman, S. J., Boushey, H. A., Fahy, J. V., Kraft, M. & 9 others, , Dec 1 2011, In: American Journal of Respiratory and Critical Care Medicine. 184, 11, p. 1247-1253 7 p.Research output: Contribution to journal › Article › peer-review
60 Scopus citations -
Impact of Age and Sex on Outcomes and Hospital Cost of Acute Asthma in the United States, 2011-2012
Zein, J. G., Udeh, B. L., Teague, W. G., Koroukian, S. M., Schlitz, N. K., Bleecker, E. R., Busse, W. B., Calhoun, W. J., Castro, M., Comhair, S. A., Fitzpatrick, A. M., Israel, E., Wenzel, S. E., Holguin, F., Gaston, B. M. & Erzurum, S. C., Jun 2016, In: PloS one. 11, 6, e0157301.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients
Silkoff, P. E., Laviolette, M., Singh, D., FitzGerald, J. M., Kelsen, S., Backer, V., Porsbjerg, C. M., Girodet, P. O., Berger, P., Kline, J. N., Chupp, G., Susulic, V. S., Barnathan, E. S., Baribaud, F., Loza, M. J., Strambu, I., Lam, S., Eich, A., Ludwig-Sengpiel, A., Leigh, R. & 4 others, , Sep 2017, In: Journal of Allergy and Clinical Immunology. 140, 3, p. 710-719 10 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma
Zein, J., Gaston, B., Bazeley, P., DeBoer, M. D., Igo, R. P., Bleecker, E. R., Meyers, D., Comhair, S., Marozkina, N. V., Cotton, C., Patel, M., Alyamani, M., Xu, W., Busse, W. W., Calhoun, W. J., Ortega, V., Hawkins, G. A., Castro, M., Chung, K. F., Fahy, J. V. & 12 others, , Jan 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2187-2193 7 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
How cytokines co-occur across asthma patients: From bipartite network analysis to a molecular-based classification
Bhavnani, S. K., Victor, S., Calhoun, W. J., Busse, W. W., Bleecker, E., Castro, M., Ju, H., Pillai, R., Oezguen, N., Bellala, G. & Brasier, A. R., Dec 2011, In: Journal of Biomedical Informatics. 44, SUPPL. 1, p. S24-S30Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Heterogeneity of response to therapy
Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Heterogeneity of response to therapy
Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Heterogeneity of asthma in society
Divekar, R. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Heterogeneity of asthma in society
Divekar, R. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Evolution of Multidisciplinary Translational Teams (MTTs): Insights for Accelerating Translational Innovations
Wooten, K. C., Calhoun, W. J., Bhavnani, S., Rose, R. M., Ameredes, B. & Brasier, A. R., Oct 2015, In: Clinical and translational science. 8, 5, p. 542-552 11 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Ethanol metabolism, oxidative stress, and endoplasmic reticulum stress responses in the lungs of hepatic alcohol dehydrogenase deficient deer mice after chronic ethanol feeding
Kaphalia, L., Boroumand, N., Hyunsu, J., Kaphalia, B. S. & Calhoun, W. J., Jun 1 2014, In: Toxicology and Applied Pharmacology. 277, 2, p. 109-117 9 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Effects of acute ethanol exposure on cytokine production by primary airway smooth muscle cells
Kaphalia, L., Kalita, M., Kaphalia, B. & Calhoun, W., Feb 1 2016, In: Toxicology and Applied Pharmacology. 292, p. 85-93 9 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: A randomized clinical trial
Smith, L. J., Kalhan, R., Wise, R. A., Sugar, E. A., Lima, J. J., Irvin, C. G., Dozor, A. J., Holbrook, J. T., Hanania, N., Sockrider, M., Bertrand, L., Atik, M. A., Lopez, B. A., Reibman, J., DiMango, E., Rogers, L., Carapetyan, K., Rivera, K., Bryce-Robinson, N., Scheuerman, M. & 180 others, , May 26 2015, In: JAMA - Journal of the American Medical Association. 313, 20, p. 2033-2043 11 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Diagnosis and management of asthma in adults a review
McCracken, J., Veeranki, S. P., Ameredes, B. & Calhoun, W., Jul 18 2017, In: JAMA - Journal of the American Medical Association. 318, 3, p. 279-290 12 p.Research output: Contribution to journal › Review article › peer-review
66 Scopus citations -
Detrimental effects of environmental tobacco smoke in relation to asthma severity
Comhair, S. A. A., Gaston, B. M., Ricci, K. S., Hammel, J., Dweik, R. A., Teague, W. G., Meyers, D., Ampleford, E. J., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hazen, S. L. & 1 others, , 2011, In: PloS one. 6, 5, e18574.Research output: Contribution to journal › Article › peer-review
81 Scopus citations -
Determinants of exhaled breath condensate pH in a large population with asthma
Liu, L., Teague, W. G., Erzurum, S., Fitzpatrick, A., Mantri, S., Dweik, R. A., Bleecker, E. R., Meyers, D., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hunt, J. F. & Gaston, B., Feb 1 2011, In: Chest. 139, 2, p. 328-336 9 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
Cytokine-induced glucocorticoid resistance from eosinophil activation: Protein phosphatase 5 modulation of glucocorticoid receptor phosphorylation and signaling
Pazdrak, K., Straub, C., Maroto, R., Stafford, S., White, W. I., Calhoun, W. J. & Kurosky, A., Nov 15 2016, In: Journal of Immunology. 197, 10, p. 3782-3791 10 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Current prospective of aldose reductase inhibition in the therapy of allergic airway inflammation in asthma
Ramana, K. V., Yadav, U. C. S., Calhoun, W. J. & Srivastava, S. K., Jan 1 2011, In: Current molecular medicine. 11, 7, p. 599-608 10 p.Research output: Contribution to journal › Review article › peer-review
6 Scopus citations -
Conclusions and future directions
Calhoun, W. J. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Conclusions and future directions
Calhoun, W. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: The BASALT randomized controlled trial
Calhoun, W. J., Ameredes, B. T., King, T. S., Icitovic, N., Bleecker, E. R., Castro, M., Cherniack, R. M., Chinchilli, V. M., Craig, T., Denlinger, L., DiMango, E. A., Engle, L. L., Fahy, J. V., Grant, J. A., Israel, E., Jarjour, N., Kazani, S. D., Kraft, M., Kunselman, S. J., Lazarus, S. C. & 15 others, , Sep 5 2012, In: JAMA - Journal of the American Medical Association. 308, 10, p. 987-997 11 p.Research output: Contribution to journal › Article › peer-review
124 Scopus citations -
Clinical implications of having reduced mid forced expiratory flow rates (FEF25-75), independently of FEV1, in adult patients with asthma
Riley, C. M., Wenzel, S. E., Castro, M., Erzurum, S. C., Chung, K. F., Fitzpatrick, A. M., Gaston, B., Israel, E., Moore, W. C., Bleecker, E. R., Calhoun, W. J., Jarjour, N. N., Busse, W. W., Peters, S. P., Teague, W. G., Sorkness, R. & Holguin, F., Dec 2015, In: PloS one. 10, 12, e0145476.Research output: Contribution to journal › Article › peer-review
18 Scopus citations