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Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling
Aguilera-Aguirre, L., Hosoki, K., Bacsi, A., Radák, Z., Sur, S., Hegde, M. L., Tian, B., Saavedra-Molina, A., Brasier, A. R., Ba, X. & Boldogh, I., Dec 1 2015, In: Free Radical Biology and Medicine. 89, p. 20-33 14 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes
Aguilera-Aguirre, L., Hosoki, K., Bacsi, A., Radák, Z., Wood, T. G., Widen, S. G., Sur, S., Ameredes, B. T., Saavedra-Molina, A., Brasier, A. R., Ba, X. & Boldogh, I., Apr 2015, In: Free Radical Biology and Medicine. 81, p. 107-118 12 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
The systemic role of SIRT1 in exercise mediated adaptation
Radak, Z., Suzuki, K., Posa, A., Petrovszky, Z., Koltai, E. & Boldogh, I., Aug 2020, In: Redox Biology. 35, 101467.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis
Chatterjee, A., Saha, S., Chakraborty, A., Silva-Fernandes, A., Mandal, S. M., Neves-Carvalho, A., Liu, Y., Pandita, R. K., Hegde, M. L., Hegde, P. M., Boldogh, I., Ashizawa, T., Koeppen, A. H., Pandita, T. K., Maciel, P., Sarkar, P. S. & Hazra, T. K., 2015, In: PLoS genetics. 11, 1, e1004749.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
The role of 8-oxoguanine DNA glycosylase-1 in inflammation
Ba, X., Aguilera-Aguirre, L., Rashid, Q. T. A. N., Bacsi, A., Radak, Z., Sur, S., Hosoki, K., Hegde, M. L. & Boldogh, I., Sep 23 2014, In: International journal of molecular sciences. 15, 9, p. 16975-16997 23 p.Research output: Contribution to journal › Review article › peer-review
52 Scopus citations -
The redox-associated adaptive response of brain to physical exercise
Radak, Z., Ihasz, F., Koltai, E., Goto, S., Taylor, A. W. & Boldogh, I., Jan 1 2014, In: Free Radical Research. 48, 1, p. 84-92 9 p.Research output: Contribution to journal › Review article › peer-review
30 Scopus citations -
The rate of training response to aerobic exercise affects brain function of rats
Marton, O., Koltai, E., Takeda, M., Mimura, T., Pajk, M., Abraham, D., Koch, L. G., Britton, S. L., Higuchi, M., Boldogh, I. & Radak, Z., Oct 1 2016, In: Neurochemistry International. 99, p. 16-23 8 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
The Potential Role of 8-Oxoguanine DNA Glycosylase-Driven DNA Base Excision Repair in Exercise-Induced Asthma
Belanger, K. A. K., Ameredes, B. T., Boldogh, I. & Aguilera-Aguirre, L., 2016, In: Mediators of inflammation. 2016, 3762561.Research output: Contribution to journal › Review article › peer-review
5 Scopus citations -
The effects of aging, physical training, and a single bout of exercise on mitochondrial protein expression in human skeletal muscle
Bori, Z., Zhao, Z., Koltai, E., Fatouros, I. G., Jamurtas, A. Z., Douroudos, I. I., Terzis, G., Chatzinikolaou, A., Sovatzidis, A., Draganidis, D., Boldogh, I. & Radak, Z., Jun 2012, In: Experimental Gerontology. 47, 6, p. 417-424 8 p.Research output: Contribution to journal › Article › peer-review
62 Scopus citations -
The C-terminal domain (CTD) of human DNA glycosylase NEIL1 is required for forming BERosome repair complex with DNA replication proteins at the replicating genome: Dominant negative function of the CTD
Hegde, P. M., Dutta, A., Sengupta, S., Mitra, J., Adhikari, S., Tomkinson, A. E., Li, G. M., Boldogh, I., Hazra, T. K., Mitra, S. & Hegde, M. L., Aug 21 2015, In: Journal of Biological Chemistry. 290, 34, p. 20919-20933 15 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
Targeting inducible epigenetic reprogramming pathways in chronic airway remodeling
Brasier, A. R. & Boldogh, I., 2019, In: Drugs in Context. 8, 2019-8-3.Research output: Contribution to journal › Review article › peer-review
Open Access -
Systems biology approaches to understanding epithelial mesenchymal transition (EMT) in mucosal remodeling and signaling in asthma
Ijaz, T., Pazdrak, K., Kalita, M., Konig, R., Choudhary, S., Tian, B., Boldogh, I. & Brasier, A. R., Jun 2 2014, In: World Allergy Organization Journal. 7, 1, 13.Research output: Contribution to journal › Review article › peer-review
55 Scopus citations -
SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle
Koltai, E., Bori, Z., Chabert, C., Dubouchaud, H., Naito, H., Machida, S., Davies, K. J. A., Murlasits, Z., Fry, A. C., Boldogh, I. & Radak, Z., Jun 1 2017, In: Journal of Physiology. 595, 11, p. 3361-3376 16 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Roles of DNA repair enzyme OGG1 in innate immunity and its significance for lung cancer
Vlahopoulos, S., Adamaki, M., Khoury, N., Zoumpourlis, V. & Boldogh, I., Feb 2019, In: Pharmacology and Therapeutics. 194, p. 59-72 14 p.Research output: Contribution to journal › Review article › peer-review
12 Scopus citations -
Role of human DNA glycosylase Nei-like 2 (NEIL2) and single strand break repair protein polynucleotide kinase 3′-phosphatase in maintenance of mitochondrial genome
Mandal, S. M., Hegde, M. L., Chatterjee, A., Hegde, P. M., Szczesny, B., Banerjee, D., Boldogh, I., Gao, R., Falkenberg, M., Gustafsson, C. M., Sarkar, P. S. & Hazra, T. K., Jan 20 2012, In: Journal of Biological Chemistry. 287, 4, p. 2819-2829 11 p.Research output: Contribution to journal › Article › peer-review
57 Scopus citations -
Reply: Protease plays a role in ragweed pollen-induced neutrophil recruitment and epithelial barrier disruption
Hosoki, K., Brasier, A. R., Kurosky, A., Boldogh, I. & Sur, S., Feb 1 2017, In: American Journal of Respiratory Cell and Molecular Biology. 56, 2, p. 272-273 2 p.Research output: Contribution to journal › Letter › peer-review
1 Scopus citations -
Regulation of type I interferon responses by mitochondria-derived reactive oxygen species in plasmacytoid dendritic cells
Agod, Z., Fekete, T., Budai, M. M., Varga, A., Szabo, A., Moon, H., Boldogh, I., Biro, T., Lanyi, A., Bacsi, A. & Pazmandi, K., Oct 2017, In: Redox Biology. 13, p. 633-645 13 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Reactive oxygen species and allergic responses
Hosoki, K., Gandhe, R., Boldogh, I. & Sur, S., May 1 2012, Systems Biology of Free Radicals and Antioxidants. Springer-Verlag Berlin Heidelberg, p. 3239-3266 28 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
2 Scopus citations -
Ragweed Subpollen Particles of Respirable Size Activate Human Dendritic Cells
Pazmandi, K., Kumar, B. V., Szabo, K., Boldogh, I., Szoor, A., Vereb, G., Veres, A., Lanyi, A., Rajnavolgyi, E. & Bacsi, A., Dec 14 2012, In: PloS one. 7, 12, e52085.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Protective effects of resveratrol on calcium-induced oxidative stress in rat heart mitochondria
Gutiérrez-Pérez, A., Cortés-Rojo, C., Noriega-Cisneros, R., Calderón-Cortés, E., Manzo-Avalos, S., Clemente-Guerrero, M., Godínez-Hernández, D., Boldogh, I. & Saavedra-Molina, A., Apr 2011, In: Journal of Bioenergetics and Biomembranes. 43, 2, p. 101-107 7 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Preferential repair of oxidized base damage in the transcribed genes of mammalian cells
Banerjee, D., Mandal, S. M., Das, A., Hegde, M. L., Das, S., Bhakat, K. K., Boldogh, I., Sarkar, P. S., Mitra, S. & Hazra, T. K., Feb 25 2011, In: Journal of Biological Chemistry. 286, 8, p. 6006-6016 11 p.Research output: Contribution to journal › Article › peer-review
91 Scopus citations -
Poly(ADP-ribosyl)ation enhances HuR oligomerization and contributes to pro-inflammatory gene mRNA stabilization
Ke, Y., Lv, X., Fu, X., Zhang, J., Bohio, A. A., Zeng, X., Hao, W., Wang, R., Boldogh, I. & Ba, X., 2020, (Accepted/In press) In: Cellular and Molecular Life Sciences.Research output: Contribution to journal › Article › peer-review
Open Access -
Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation
Aguilera-Aguirre, L., Hao, W., Pan, L., Li, X., Saavedra-Molina, A., Bacsi, A., Radak, Z., Sur, S., Brasier, A. R., Ba, X. & Boldogh, I., Dec 2017, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 313, 6, p. L1058-L1068Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Physical exercise, reactive oxygen species and neuroprotection
Radak, Z., Suzuki, K., Higuchi, M., Balogh, L., Boldogh, I. & Koltai, E., Sep 1 2016, In: Free Radical Biology and Medicine. 98, p. 187-196 10 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
Pervasive Genomic Damage in Experimental Intracerebral Hemorrhage: Therapeutic Potential of a Mechanistic-Based Carbon Nanoparticle
Dharmalingam, P., Talakatta, G., Mitra, J., Wang, H., Derry, P. J., Nilewski, L. G., McHugh, E. A., Fabian, R. H., Mendoza, K., Vasquez, V., Hegde, P. M., Kakadiaris, E., Roy, T., Boldogh, I., Hegde, V. L., Mitra, S., Tour, J. M., Kent, T. A. & Hegde, M. L., Mar 24 2020, In: ACS Nano. 14, 3, p. 2827-2846 20 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Pathophysiology of bronchoconstriction: Role of oxidatively damaged DNA repair
Bacsi, A., Pan, L., Ba, X. & Boldogh, I., 2016, In: Current opinion in allergy and clinical immunology. 16, 1, p. 59-67 9 p.Research output: Contribution to journal › Review article › peer-review
11 Scopus citations -
PARP1 promotes gene expression at the post-transcriptiona level by modulating the RNA-binding protein HuR
Ke, Y., Han, Y., Guo, X., Wen, J., Wang, K., Jiang, X., Tian, X., Ba, X., Boldogh, I. & Zeng, X., Mar 8 2017, In: Nature communications. 8, 14632.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Oxidized guanine base lesions function in 8-oxoguanine DNA glycosylase-1-mediated epigenetic regulation of nuclear factor κB-driven gene expression
Pan, L., Zhu, B., Hao, W., Zeng, X., Vlahopoulos, S. A., Hazra, T. K., Hegde, M. L., Radak, Z., Bacsi, A., Brasier, A. R., Ba, X. & Boldogh, I., Dec 2 2016, In: Journal of Biological Chemistry. 291, 49, p. 25553-25566 14 p.Research output: Contribution to journal › Article › peer-review
74 Scopus citations -
Oxidized base 8-oxoguanine, a product of DNA repair processes, contributes to dendritic cell activation
Pázmándi, K., Sütő, M., Fekete, T., Varga, A., Boldizsár, E., Boldogh, I. & Bácsi, A., Nov 1 2019, In: Free Radical Biology and Medicine. 143, p. 209-220 12 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Oxidative stress damage-associated molecular signaling pathways differentiate spontaneous preterm birth and preterm premature rupture of the membranes
Dutta, E. H., Behnia, F., Boldogh, I., Saade, G., Taylor, B. D., Kacerovský, M. & Menon, R., Aug 28 2015, In: Molecular Human Reproduction. 22, 2, p. 143-157 15 p., gav074.Research output: Contribution to journal › Article › peer-review
74 Scopus citations -
Oxidative modification enhances the immunostimulatory effects of extracellular mitochondrial DNA on plasmacytoid dendritic cells
Pazmandi, K., Agod, Z., Kumar, B. V., Szabo, A., Fekete, T., Sogor, V., Veres, A., Boldogh, I., Rajnavolgyi, E., Lanyi, A. & Bacsi, A., 2014, In: Free Radical Biology and Medicine. 77, p. 281-290 10 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
OGG1-DNA interactions facilitate NF-k B binding to DNA targets
Pan, L., Hao, W., Zheng, X., Zeng, X., Ahmed Abbasi, A., Boldogh, I. & Ba, X., Mar 7 2017, In: Scientific reports. 7, 43297.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
NF-κB mediates mesenchymal transition, remodeling, and pulmonary fibrosis in response to chronic inflammation by viral RNA patterns
Tian, B., Patrikeev, I., Ochoa, L., Vargas, G., Belanger, K. A. K., Litvinov, J., Boldogh, I., Ameredes, B. T., Motamedi, M. & Brasier, A. R., Apr 2017, In: American journal of respiratory cell and molecular biology. 56, 4, p. 506-520 15 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases
Mitra, J., Guerrero, E. N., Hegde, P. M., Wang, H., Boldogh, I., Rao, K. S., Mitra, S. & Hegde, M. L., Sep 1 2014, In: Biomolecules. 4, 3, p. 678-703 26 p.Research output: Contribution to journal › Review article › peer-review
21 Scopus citations -
Neutrophil recruitment by allergens contribute to allergic sensitization and allergic inflammation
Hosoki, K., Itazawa, T., Boldogh, I. & Sur, S., 2016, In: Current opinion in allergy and clinical immunology. 16, 1, p. 45-50 6 p.Research output: Contribution to journal › Review article › peer-review
38 Scopus citations -
NEIL2 Protects against Oxidative DNA damage induced by sidestream smoke in human cells
Sarker, A. H., Chatterjee, A., Williams, M., Lin, S., Havel, C., Jacob, P., Boldogh, I., Hazra, T. K., Talbot, P. & Hang, B., Mar 3 2014, In: PloS one. 9, 3, e90261.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Neil2-null mice accumulate oxidized DNA bases in the transcriptionally active sequences of the genome and are susceptible to innate inflammation
Chakraborty, A., Wakamiya, M., Venkova-Canova, T., Pandita, R. K., Aguilera-Aguirre, L., Sarker, A. H., Singh, D. K., Hosoki, K., Wood, T. G., Sharma, G., Cardenas, V., Sarkar, P. S., Sur, S., Pandita, T. K., Boldogh, I. & Hazra, T. K., Oct 9 2015, In: Journal of Biological Chemistry. 290, 41, p. 24636-24648 13 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
Myeloid differentiation protein 2 facilitates pollen- and cat dander-induced innate and allergic airway inflammation
Hosoki, K., Boldogh, I., Aguilera-Aguirre, L., Sun, Q., Itazawa, T., Hazra, T., Brasier, A. R., Kurosky, A. & Sur, S., May 1 2016, In: Journal of Allergy and Clinical Immunology. 137, 5, p. 1506-1513.e2Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects
Mitra, J., Guerrero, E. N., Hegde, P. M., Liachko, N. F., Wang, H., Vasquez, V., Gao, J., Pandey, A., Paul Taylor, J., Kraemer, B. C., Wu, P., Boldogh, I., Garruto, R. M., Mitra, S., Rao, K. S. & Hegde, M. L., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 10, p. 4696-4705 10 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Modulatory effects of low-dose hydrogen peroxide on the function of human plasmacytoid dendritic cells
Pazmandi, K., Magyarics, Z., Boldogh, I., Csillag, A., Rajnavolgyi, E. & Bacsi, A., Feb 1 2012, In: Free Radical Biology and Medicine. 52, 3, p. 635-645 11 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Mitochondrial dysfunctions related with oxidative stress
Saavedra-Molina, A., Boldogh, I., Manzo-Avalos, S., Cortés-Rojo, C., Aguilera-Aguirre, L., Montoya-Pérez, R. & Bacsi, A., 2011, Mitochondria: Structure, Functions and Dysfunctions. Nova Science Publishers, Inc., p. 411-439 29 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Mitochondrial biogenesis-associated factors underlie the magnitude of response to aerobic endurance training in rats
Marton, O., Koltai, E., Takeda, M., Koch, L. G., Britton, S. L., Davies, K. J. A., Boldogh, I. & Radak, Z., Jan 1 2015, In: Pflugers Archiv European Journal of Physiology. 467, 4, p. 779-788 10 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Inside-Out Signaling Pathways from Nuclear Reactive Oxygen Species Control Pulmonary Innate Immunity
Choudhary, S., Boldogh, I. & Brasier, A. R., Mar 1 2016, In: Journal of Innate Immunity. 8, 2, p. 143-155 13 p.Research output: Contribution to journal › Review article › peer-review
23 Scopus citations -
Innate responses to pollen allergens
Hosoki, K., Boldogh, I. & Sur, S., Feb 13 2015, In: Current opinion in allergy and clinical immunology. 15, 1, p. 79-88 10 p.Research output: Contribution to journal › Review article › peer-review
17 Scopus citations -
Innate mechanism of pollen- and cat dander–induced oxidative stress and DNA damage in the airways
Hosoki, K., Redding, D., Itazawa, T., Chakraborty, A., Tapryal, N., Qian, S., Qi, H., Aguilera-Aguirre, L., Brasier, A. R., Phani, V. S., Hazra, T. K., Boldogh, I. & Sur, S., Nov 2017, In: Journal of Allergy and Clinical Immunology. 140, 5, p. 1436-1439.e5Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-κB pathway
Aguilera-Aguirre, L., Bacsi, A., Radak, Z., Hazra, T. K., Mitra, S., Sur, S., Brasier, A. R., Ba, X. & Boldogh, I., Nov 1 2014, In: Journal of Immunology. 193, 9, p. 4643-4653 11 p.Research output: Contribution to journal › Article › peer-review
60 Scopus citations -
Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2
Dey, S., Maiti, A. K., Hegde, M. L., Hegde, P. M., Boldogh, I., Sarkar, P. S., Abdel-Rahman, S. Z., Sarker, A. H., Hang, B., Xie, J., Tomkinson, A. E., Zhou, M., Shen, B., Wang, G., Wu, C., Yu, D., Lin, D., Cardenas, V. & Hazra, T. K., Jun 1 2012, In: DNA Repair. 11, 6, p. 570-578 9 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
Hypolipidemic activity of eryngium carlinae on streptozotocin-induced diabetic rats
Noriega-Cisneros, R., Ortiz-Vila, O., Esquivel-Gutiérrez, E., Clemente-Guerrero, M., Manzo-Avalos, S., Salgado-Garciglia, R., Cortés-Rojo, C., Boldogh, I. & Saavedra-Molina, A., 2012, In: Biochemistry Research International. 603501.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Human DNA glycosylase NEIL1's interactions with downstream repair proteins is critical for efficient repair of oxidized DNA base damage and enhanced cell survival
Hegde, M. L., Hegde, P. M., Arijit, D., Boldogh, I. & Mitra, S., Dec 2012, In: Biomolecules. 2, 4, p. 564-578 15 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Histological evidence of oxidative stress and premature senescence in preterm premature rupture of the human fetal membranes recapitulated in vitro
Menon, R., Boldogh, I., Hawkins, H. K., Woodson, M., Polettini, J., Syed, T. A., Fortunato, S. J., Saade, G. R., Papaconstantinou, J. & Taylor, R. N., Jun 2014, In: American Journal of Pathology. 184, 6, p. 1740-1751 12 p.Research output: Contribution to journal › Article › peer-review
111 Scopus citations