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• The two-component QseBC signalling system regulates in vitro and in vivo virulence of Aeromonas hydrophila

  Khajanchi, B. K., Kozlova, E. V., Sha, J., Popov, V. L. & Chopra, A. K., Jan 2012, In: Microbiology. 158, 1, p. 259-271 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Quorum Sensing
  • Virulence
  • N-(3-oxohexanoyl)-3-aminodihydro-2(3H)-furanone
  • N-octanoylhomoserine lactone
  44 Scopus citations

• T6SS and ExoA of flesh-eating Aeromonas hydrophila in peritonitis and necrotizing fasciitis during mono- And polymicrobial infections

  Fernández-Bravo, A., Kilgore, P. B., Andersson, J. A., Blears, E., Figueras, M. J., Hasan, N. A., Colwell, R. R., Sha, J. & Chopra, A. K., Nov 26 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 48, p. 24084-24092 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Type VI Secretion Systems
  • Aeromonas hydrophila
  • Exotoxins
  • Necrotizing Fasciitis
  • Peritonitis
  5 Scopus citations

• Quorum sensing and c-di-GMP-dependent alterations in gene transcripts and virulence-associated phenotypes in a clinical isolate of Aeromonas hydrophila

  Kozlova, E. V., Khajanchi, B. K., Sha, J. & Chopra, A. K., May 2011, In: Microbial Pathogenesis. 50, 5, p. 213-223 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Quorum Sensing
  • Biofilms
  • Virulence
  • Phenotype
  26 Scopus citations

• Protective immunity elicited by oral immunization of mice with Salmonella enterica serovar typhimurium braun lipoprotein (Lpp) and acetyltransferase (MsbB) mutants

  Erova, T. E., Kirtley, M. L., Fitts, E. C., Ponnusamy, D., Baze, W. B., Andersson, J. A., Cong, Y., Tiner, B. L., Sha, J. & Chopra, A. K., Nov 10 2016, In: Frontiers in Cellular and Infection Microbiology. 6, NOV, 148.

  Research output: Contribution to journal › Article › peer-review

  • Acetyltransferases
  • Salmonella enterica
  • Lipoproteins
  • Serogroup
  • Immunization
  8 Scopus citations

• Progress on plague vaccine development

  Rosenzweig, J. A., Jejelowo, O., Sha, J., Erova, T. E., Brackman, S. M., Kirtley, M. L., Van Lier, C. J. & Chopra, A. K., Jul 1 2011, In: Applied Microbiology and Biotechnology. 91, 2, p. 265-286 22 p.

  Research output: Contribution to journal › Review article › peer-review

  • Plague Vaccine
  • Yersinia pestis
  • Plague
  • Vaccines
  • Yersinia pseudotuberculosis
  29 Scopus citations

• New role for FDA-approved drugs in combating antibiotic-resistant bacteria

  Andersson, J. A., Fitts, E. C., Kirtley, M. L., Ponnusamy, D., Peniche, A. G., Dann, S. M., Motin, V. L., Chauhan, S., Rosenzweig, J. A., Sha, J. & Chopra, A. K., Jun 2016, In: Antimicrobial agents and chemotherapy. 60, 6, p. 3717-3729 13 p.

  Research output: Contribution to journal › Article › peer-review

  • United States Food and Drug Administration
  • Yersinia pestis
  • Trifluoperazine
  • Bacteria
  • Anti-Bacterial Agents
  18 Scopus citations

• New insights into autoinducer-2 signaling as a virulence regulator in a mouse model of pneumonic plague

  Fitts, E. C., Andersson, J. A., Kirtley, M. L., Sha, J., Erova, T. E., Chauhan, S., Motin, V. L. & Chopra, A. K., Nov 1 2016, In: mSphere. 1, 6, e00342-16.

  Research output: Contribution to journal › Article › peer-review

  • N-octanoylhomoserine lactone
  • Plague
  • Virulence
  • Yersinia pestis
  • Bacterial Genes
  6 Scopus citations

• New host-directed therapeutics for the treatment of Clostridioides difficile infection

  Andersson, J. A., Peniche, A. G., Galindo, C. L., Boonma, P., Sha, J., Luna, R. A., Savidge, T. C., Chopra, A. K. & Dann, S. M., Mar 1 2020, In: mBio. 11, 2, e00053-20.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Amoxapine
  • Infection
  • Interleukin-33
  • Pharmaceutical Preparations
  • Doxapram

• Immunisation of two rodent species with new live-attenuated mutants of Yersinia pestis CO92 induces protective long-term humoral- and cell-mediated immunity against pneumonic plague

  Tiner, B. L., Sha, J., Cong, Y., Kirtley, M. L., Andersson, J. A. & Chopra, A. K., Oct 13 2016, In: npj Vaccines. 1, 16020.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Plague
  • Cellular Immunity
  • Immunization
  • Rodentia
  7 Scopus citations

• Functional genomic characterization of virulence factors from necrotizing fasciitis-causing strains of Aeromonas hydrophila

  Grim, C. J., Kozlova, E. V., Ponnusamy, D., Fitts, E. C., Sha, J., Kirtley, M. L., van Lier, C. J., Tiner, B. L., Erova, T. E., Joseph, S. J., Read, T. D., Shak, J. R., Joseph, S. W., Singletary, E., Felland, T., Baze, W. B., Horneman, A. J. & Chopra, A. K., 2014, In: Applied and Environmental Microbiology. 80, 14, p. 4162-4183 22 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • virulence
  • Necrotizing Fasciitis
  • Aeromonas
  • virulent strains
  37 Scopus citations

• DNA adenine methyltransferase (Dam) controls the expression of the cytotoxic enterotoxin (act) gene of Aeromonas hydrophila via tRNA modifying enzyme-glucose-inhibited division protein (GidA)

  Erova, T. E., Kosykh, V. G., Sha, J. & Chopra, A. K., May 1 2012, In: Gene. 498, 2, p. 280-287 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Enterotoxins
  • Adenine
  • Methyltransferases
  • Transfer RNA
  11 Scopus citations

• Deletion of braun lipoprotein and plasminogen-activating protease-encoding genes attenuates Yersinia pestis in mouse models of bubonic and pneumonic plague

  Van Lier, C. J., Sha, J., Kirtley, M. L., Cao, A., Tiner, B. L., Erova, T. E., Cong, Y., Kozlova, E. V., Popov, V. L., Baze, W. B. & Chopra, A. K., 2014, In: Infection and immunity. 82, 6, p. 2485-2503 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Plague
  • Plasminogen
  • Lipoproteins
  • Peptide Hydrolases
  19 Scopus citations

• Cross-talk among flesh-eating Aeromonas hydrophila strains in mixed infection leading to necrotizing fasciitis

  Ponnusamy, D., Kozlova, E. V., Sha, J., Erova, T. E., Azar, S. R., Fitts, E. C., Kirtley, M. L., Tiner, B. L., Andersson, J. A., Grim, C. J., Isom, R. P., Hasan, N. A., Colwell, R. R. & Chopra, A. K., Jan 19 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 3, p. 722-727 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Exotoxins
  • Necrotizing Fasciitis
  • Coinfection
  • Virulence
  36 Scopus citations

• Characterization of an F1 deletion mutant of Yersinia pestis CO92, pathogenic role of F1 antigen in bubonic and pneumonic plague, and evaluation of sensitivity and specificity of F1 antigen capture-based dipsticks

  Sha, J., Endsley, J. J., Kirtley, M. L., Foltz, S. M., Huante, M. B., Erova, T. E., Kozlova, E. V., Popov, V. L., Yeager, L. A., Zudina, I. V., Motin, V. L., Peterson, J. W., DeBord, K. L. & Chopra, A. K., May 2011, In: Journal of Clinical Microbiology. 49, 5, p. 1708-1715 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Plague
  • Sensitivity and Specificity
  • Antigens
  • Homologous Recombination
  25 Scopus citations

• Cethromycin-mediated protection against the plague pathogen Yersinia pestis in a rat model of infection and comparison with levofloxacin

  Rosenzweig, J. A., Brackman, S. M., Kirtley, M. L., Sha, J., Erova, T. E., Yeager, L. A., Peterson, J. W., Xu, Z. Q. & Chopra, A. K., Nov 2011, In: Antimicrobial agents and chemotherapy. 55, 11, p. 5034-5042 9 p.

  Research output: Contribution to journal › Article › peer-review

  • cethromycin
  • Yersinia pestis
  • Plague
  • Levofloxacin
  • Infection
  14 Scopus citations

• A Replication-Defective human type 5 adenovirus-based trivalent vaccine confers complete protection against plague in mice and nonhuman primates

  Sha, J., Kirtley, M. L., Klages, C., Erova, T. E., Telepnev, M., Ponnusamy, D., Fitts, E. C., Baze, W. B., Sivasubramani, S. K., Lawrence, W. S., Patrikeev, I., Peel, J. E., Andersson, J. A., Kozlova, E. V., Tiner, B. L., Peterson, J. W., Mcwilliams, D., Patel, S., Rothe, E., Motin, V. L. & 1 others, Chopra, A. K., Jul 2016, In: Clinical and Vaccine Immunology. 23, 7, p. 586-600 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Human Adenoviruses
  • Plague
  • Primates
  • Vaccines
  • Antigens
  12 Scopus citations

• A prokaryotic-eukaryotic hybrid viral vector for delivery of large cargos of genes and proteins into human cells

  Zhu, J., Tao, P., Mahalingam, M., Sha, J., Kilgore, P., Chopra, A. K. & Rao, V., Aug 21 2019, In: Science Advances. 5, 8, eaax0064.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • viruses
  • genes
  • delivery
  • proteins
  • biotin
  2 Scopus citations

• Actin cross-linking domain of Aeromonas hydrophila repeat in toxin A (RtxA) induces host cell rounding and apoptosis

  Suarez, G., Khajanchi, B. K., Sierra, J. C., Erova, T. E., Sha, J. & Chopra, A. K., Sep 15 2012, In: Gene. 506, 2, p. 369-376 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Actins
  • Apoptosis
  • Vibrio
  • Operon
  23 Scopus citations