Find Research outputs — UTMB Health Research Expert Profiles

Value of autopsy emphasized in the case report of a single patient with middle east respiratory syndrome

Walker, D. H., Mar 1 2016, In: American Journal of Pathology. 186, 3, p. 507-510 4 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Time to Worry about Anthrax Again

Keim, P. S., Walker, D. H. & Zilinskas, R. A., Mar 14 2017, In: Scientific American. 316, 4, p. 70-75 6 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

The role of Rhipicephalus sanguineus sensu lato saliva in the dissemination of Rickettsia conorii in C3H/HeJ mice

Milhano, N., Saito, T. B., Bechelli, J., Fang, R., Vilhena, M., De Sousa, R. & Walker, D. H., Sep 1 2015, In: Medical and Veterinary Entomology. 29, 3, p. 225-229 5 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

The role of CD8 T lymphocytes in rickettsial infections

Walker, D. H. & Dumler, J. S., May 26 2015, In: Seminars in Immunopathology. 37, 3, p. 289-299 11 p.

Research output: Contribution to journal › Review article › peer-review

17 Scopus citations

The guinea pig model for tick-borne spotted fever rickettsioses: A second look

Stokes, J. V., Walker, D. H. & Varela-Stokes, A. S., Nov 2020, In: Ticks and Tick-borne Diseases. 11, 6, 101538.

Research output: Contribution to journal › Review article › peer-review

Open Access

Systemic treatment with cpg-b after sublethal rickettsial infection induces mouse death through indoleamine 2,3-dioxygenase (ido)

Xin, L., Shelite, T. R., Gong, B., Mendell, N. L., Soong, L., Fang, R. & Walker, D. H., Mar 28 2012, In: PloS one. 7, 3, e34062.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Spotted fever group Rickettsia in small rodents from areas of low endemicity for Brazilian spotted fever in the Eastern Region of Minas Gerais State, Brazil

Milagres, B. S., Padilha, A. F., Montandon, C. E., Freitas, R. N., Pacheco, R., Walker, D. H., Labruna, M. B., Mafra, C. L. & Galvão, M. A. M., May 2013, In: American Journal of Tropical Medicine and Hygiene. 88, 5, p. 937-939 3 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Simple method to differentiate among Rickettsia species

Peniche-Lara, G., Zavala-Velazquez, J., Dzul-Rosado, K., Walker, D. H. & Zavala-Castro, J., Apr 1 2013, In: Journal of Molecular Microbiology and Biotechnology. 23, 3, p. 203-208 6 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Scrub typhus - Scientific neglect, ever-widening impact

Walker, D. H., Sep 8 2016, In: New England Journal of Medicine. 375, 10, p. 913-915 3 p.

Research output: Contribution to journal › Short survey › peer-review

32 Scopus citations

Rocky mountain spotted fever and other rickettsioses

Walker, D., May 15 2012, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Rocky mountain spotted fever and other rickettsioses

Walker, D., Jul 8 2013, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Rickettsia massiliae and rickettsia conorii israeli spotted fever strain differentially regulate endothelial cell responses

Bechelli, J., Smalley, C., Milhano, N., Walker, D. H. & Fang, R., Sep 22 2015, In: PloS one. 10, 9, e0138830.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Rickettsiae as Emerging Infectious Agents

Fang, R., Blanton, L. S. & Walker, D. H., Jun 2017, In: Clinics in Laboratory Medicine. 37, 2, p. 383-400 18 p.

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Rickettsia australis activates inflammasome in human and murine macrophages

Smalley, C., Bechelli, J., Rockx-Brouwer, D., Saito, T., Azar, S. R., Ismail, N., Walker, D. H. & Fang, R., Jun 2016, In: PloS one. 11, 6, e0157231.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Rickettsia, orientia, ehrlichia, anaplasma and coxiella: Typhus; spotted fevers; scrub typhus; ehrlichioses; Q fever

Walker, D. & Yu, X. J., Jul 23 2012, Medical Microbiology: Eighteenth Edition. Elsevier Inc., p. 390-399 10 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Rickettsia

Walker, D., Oct 6 2016, International Encyclopedia of Public Health. Elsevier Inc., p. 370-377 8 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Review article: Unresolved problems related to scrub typhus: A seriously neglected life-threatening disease

Paris, D. H., Shelite, T. R., Day, N. P. & Walker, D. H., Aug 2013, In: American Journal of Tropical Medicine and Hygiene. 89, 2, p. 301-307 7 p.

Research output: Contribution to journal › Review article › peer-review

135 Scopus citations

Reemergence of murine typhus in galveston, texas, usa, 2013

Blanton, L. S., Vohra, R. F., Bouyer, D. H. & Walker, D. H., 2015, In: Emerging infectious diseases. 21, 3, p. 484-486 3 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis

Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In: Vaccine. 31, 50, p. 5960-5967 8 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Recent research milestones in the pathogenesis of human rickettsioses and opportunities ahead

Narra, H. P., Sahni, A., Walker, D. H. & Sahni, S. K., Jun 2020, In: Future Microbiology. 15, 9, p. 753-765 13 p.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Recent molecular insights into rickettsial pathogenesis and immunity

Sahni, S. K., Narra, H. P., Sahni, A. & Walker, D. H., Oct 2013, In: Future Microbiology. 8, 10, p. 1265-1288 24 p.

Research output: Contribution to journal › Review article › peer-review

59 Scopus citations

Quantitative Proteomics of the Endothelial Secretome Identifies RC0497 as Diagnostic of Acute Rickettsial Spotted Fever Infections

Zhao, Y., Fang, R., Zhang, J., Zhang, Y., Bechelli, J., Smalley, C., Valbuena, G., Walker, D. H., Oteo, J. A. & Brasier, A. R., Feb 2020, In: American Journal of Pathology. 190, 2, p. 306-322 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Perspective Piece: Ideal Criteria for Accurate Mouse Models of Vector-Borne Diseases with Emphasis on Scrub Typhus and Dengue

Sarathy, V. V. & Walker, D. H., Sep 2020, In: American Journal of Tropical Medicine and Hygiene. 103, 3, p. 970-975 6 p.

Research output: Contribution to journal › Review article › peer-review

Person-to-person transmission of severe fever with thrombocytopenia syndrome virus

Liu, Y., Li, Q., Hu, W., Wu, J., Weng, Y., Mei, L., Walker, D. H., Ren, J., Wang, Y. & Yu, X. J., Feb 1 2012, In: Vector-Borne and Zoonotic Diseases. 12, 2, p. 156-160 5 p.

Research output: Contribution to journal › Article › peer-review

154 Scopus citations

Permissive and protective roles for neutrophils in leishmaniasis

Carlsen, E. D., Liang, Y., Shelite, T. R., Walker, D. H., Melby, P. C. & Soong, L., Nov 2015, In: Clinical and Experimental Immunology. 182, 2, p. 109-18 10 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Pathogenesis of the viral hemorrhagic fevers

Paessler, S. & Walker, D. H., Jan 2013, In: Annual Review of Pathology: Mechanisms of Disease. 8, p. 411-440 30 p.

Research output: Contribution to journal › Review article › peer-review

156 Scopus citations

Pathogenesis of lassa fever

Yun, N. E. & Walker, D. H., Oct 2012, In: Viruses. 4, 10, p. 2031-2048 18 p.

Research output: Contribution to journal › Review article › peer-review

89 Scopus citations

Opossums and cat fleas: New insights in the ecology of murine typhus in Galveston, Texas

Blanton, L. S., Idowu, B. M., Tatsch, T. N., Henderson, J. M., Bouyer, D. H. & Walker, D. H., Aug 2016, In: American Journal of Tropical Medicine and Hygiene. 95, 2, p. 457-461 5 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

New insight into immunity and immunopathology of Rickettsial diseases

Mansueto, P., Vitale, G., Cascio, A., Seidita, A., Pepe, I., Carroccio, A., Di Rosa, S., Rini, G. B., Cillari, E. & Walker, D. H., 2012, In: Clinical and Developmental Immunology. 2012, 967852.

Research output: Contribution to journal › Review article › peer-review

83 Scopus citations

MyD88 mediates instructive signaling in dendritic cells and protective inflammatory response during rickettsial infection

Bechelli, J., Smalley, C., Zhao, X., Judy, B., Valdes, P., Walker, D. H. & Fang, R., Apr 1 2016, In: Infection and immunity. 84, 4, p. 883-893 11 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Murine models of scrub typhus associated with host control of Orientia tsutsugamushi infection

Mendell, N. L., Bouyer, D. H. & Walker, D. H., Mar 10 2017, In: PLoS neglected tropical diseases. 11, 3, e0005453.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus

Yun, N. E., Seregin, A. V., Walker, D. H., Popov, V. L., Walker, A. G., Smith, J. N., Miller, M., de la Torre, J. C., Smith, J. K., Borisevich, V., Fair, J. N., Wauquier, N., Grant, D. S., Bockarie, B., Bente, D. & Paessler, S., 2013, In: Journal of virology. 87, 19, p. 10908-10911 4 p.

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Mechanisms of immunity to rickettsia and implications for vaccine development

Walker, D., Jan 1 2017, In: Revista Colombiana de Ciencias Pecuarias. 30, p. 262-263 2 p.

Research output: Contribution to journal › Article › peer-review

Letters to the editor

Walker, D., Mar 2012, In: Archives of Pathology and Laboratory Medicine. 136, 3, p. 235-236 2 p.

Research output: Contribution to journal › Letter › peer-review

Immune Mediators of protective and pathogenic immune responses in patients with mild and fatal human monocytotropic ehrlichiosis

Ismail, N., Walker, D. H., Ghose, P. & Tang, Y. W., May 21 2012, In: BMC Immunology. 13, 26.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Human rickettsiosis caused by rickettsia parkeri strain Atlantic rainforest, Urabá, Colombia

Arboleda, M., Acevedo-Gutiérrez, L. Y., Ávila, A., Ospina, D., Díaz, F. J., Walker, D. H. & Rodas, J. D., Dec 2020, In: Emerging infectious diseases. 26, 12, p. 3048-3050 3 p.

Research output: Contribution to journal › Article › peer-review

Human monocytic ehrlichiosis, Mexico City, Mexico

Alcántara-Rodríguez, V. E., Sánchez-Montes, S., Contreras, H., Colunga-Salas, P., Fierro-Flores, L., Avalos, S., Rodríguez-Rangel, F., Becker, I. & Walker, D. H., Dec 2020, In: Emerging infectious diseases. 26, 12, p. 3016-3019 4 p.

Research output: Contribution to journal › Article › peer-review

Human ehrlichioses and rickettsioses in Cameroon

Ndip, LN., Ndip, R., Walker, D. H. & McBride, J. W., 2012, Current Topics in Tropical Medicine. p. 25-42

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Genotypic characterization of Orientia tsutsugamushi from patients in two geographical locations in Sri Lanka

Premaratna, R., Blanton, L. S., Samaraweera, D. N., de Silva, G. N. N., Chandrasena, N. T. G. A., Walker, D. H. & de Silva, H. J., Jan 13 2017, In: BMC Infectious Diseases. 17, 1, 67.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Flea-Borne Rickettsioses and Rickettsiae

Blanton, L. S. & Walker, D. H., Jan 2017, In: American Journal of Tropical Medicine and Hygiene. 96, 1, p. 53-56 4 p.

Research output: Contribution to journal › Review article › peer-review

33 Scopus citations

Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium

Sahni, A., Patel, J., Narra, H. P., Schroeder, C. L. C., Walker, D. H. & Sahni, S. K., Aug 2017, In: PloS one. 12, 8, e0183181.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Fever and rash after a safari

Damavandy, A. A., Rojek, N. W., Dugan, E. M., Walker, D. & Norton, S. A., Jan 1 2015, In: Journal of the American Academy of Dermatology. 72, 1, p. e5-e6

Research output: Contribution to journal › Article › peer-review

Fatal monocytic ehrlichiosis in woman, Mexico, 2013

Sosa-Gutierrez, C. G., Solorzano-Santos, F., Walker, D. H., Torres, J., Serrano, C. A. & Gordillo-Perez, G., May 2016, In: Emerging infectious diseases. 22, 5, p. 871-874 4 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses

Gong, B., Shelite, T., Mei, F. C., Ha, T., Hu, Y., Xu, G., Chang, Q., Wakamiya, M., Ksiazek, T. G., Boor, P. J., Bouyer, D. H., Popov, V. L., Chen, J., Walker, D. H. & Cheng, X., Nov 26 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 48, p. 19615-19620 6 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Epidemiology, molecular biology, and pathogenic mechanisms of Ehrlichia infections

Yu, X. J. & Walker, D., Jan 1 2016, Rickettsiales: Biology, Molecular Biology, Epidemiology, and Vaccine Development. Springer International Publishing, p. 225-240 16 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Endothelial cell proteomic response to Rickettsia conorii infection reveals activation of the Janus Kinase (JAK)-signal transducer and activator of transcription (STAT)-inferferon stimulated gene (ISG)15 pathway and reprogramming plasma membrane integrin/cadherin signaling

Zhao, Y., Valbuena, G., Walker, D. H., Gazi, M., Hidalgo, M., DeSousa, R., Oteo, J. A., Goez, Y. & Brasier, A. R., Jan 2016, In: Molecular and Cellular Proteomics. 15, 1, p. 289-304 16 p.

Research output: Contribution to journal › Article › peer-review