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• Differential activation of the ER stress factor XBP1 by oligomeric assemblies

  Castillo-Carranza, D. L., Zhang, Y., Guerrero-Muñoz, M. J., Kayed, R., Rincon-Limas, D. E. & Fernandez-Funez, P., Aug 2012, In: Neurochemical Research. 37, 8, p. 1707-1717 11 p.

  Research output: Contribution to journal › Article › peer-review

  • X-Box Binding Protein 1
  • Factor X
  • Oligomers
  • Amyloid
  • Chemical activation
  25 Scopus citations

• Critical Role of the CXCL10/C-X-C Chemokine Receptor 3 Axis in Promoting Leukocyte Recruitment and Neuronal Injury during Traumatic Optic Neuropathy Induced by Optic Nerve Crush

  Ha, Y., Liu, H., Zhu, S., Yi, P., Liu, W., Nathanson, J., Kayed, R., Loucas, B., Sun, J., Frishman, L. J., Motamedi, M. & Zhang, W., Feb 1 2017, In: American Journal of Pathology. 187, 2, p. 352-365 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Optic Nerve Injuries
  • Nerve Crush
  • CXC Chemokines
  • Chemokine Receptors
  • Optic Nerve
  17 Scopus citations

• Corrigendum: Pre-amyloid oligomers budding:a metastatic mechanism of proteotoxicity

  Bernini, F., Malferrari, D., Pignataro, M., Bortolotti, C. A., Di Rocco, G., Lancellotti, L., Brigatti, M. F., Kayed, R., Borsari, M., Del Monte, F. & Castellini, E., Jan 19 2017, In: Scientific reports. 7, 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Cerebral microvascular accumulation of tau oligomers in Alzheimer's disease and related tauopathies

  Castillo-Carranza, D. L., Nilson, A. N., Van Skike, C. E., Jahrling, J. B., Patel, K., Garach, P., Gerson, J. E., Sengupta, U., Abisambra, J., Nelson, P., Troncoso, J., Ungvari, Z., Galvan, V. & Kayed, R., 2017, In: Aging and Disease. 8, 3, p. 257-266 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Tauopathies
  • Alzheimer Disease
  • Progressive Supranuclear Palsy
  • Lewy Body Disease
  • Blood Vessels
  32 Scopus citations

• Caspase-cleaved tau exhibits rapid memory impairment associated with tau oligomers in a transgenic mouse model

  Kim, Y. D., Choi, H., Lee, W. J., Park, H., Kam, T. I., Hong, S. H., Nah, J., Jung, S., Shin, B., Lee, H., Choi, T. Y., Choo, H., Kim, K. K., Choi, S. Y., Kayed, R. & Jung, Y. K., Mar 1 2016, In: Neurobiology of Disease. 87, p. 19-28 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Caspases
  • Transgenic Mice
  • Memory
  • Memory Disorders
  • Hippocampus
  33 Scopus citations

• Binding and neurotoxicity mitigation of toxic tau oligomers by synthetic heparin like oligosaccharides

  Wang, P., Lo Cascio, F., Gao, J., Kayed, R. & Huang, X., 2018, In: Chemical Communications. 54, 72, p. 10120-10123 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Oligosaccharides
  • Heparin
  • Oligomers
  • Poisons
  • Cytotoxicity
  10 Scopus citations

• Aβ Amyloid Pathology Affects the Hearts of Patients With Alzheimer's Disease: Mind the Heart

  Troncone, L., Luciani, M., Coggins, M., Wilker, E. H., Ho, C. Y., Codispoti, K. E., Frosch, M. P., Kayed, R. & del Monte, F., Dec 6 2016, In: Journal of the American College of Cardiology. 68, 22, p. 2395-2407 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Amyloid
  • Heart Diseases
  • Alzheimer Disease
  • Heart
  • Pathology
  60 Scopus citations

• Azure C Targets and Modulates Toxic Tau Oligomers

  Lo Cascio, F. & Kayed, R., Jun 20 2018, In: ACS Chemical Neuroscience. 9, 6, p. 1317-1326 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Azure C
  • Oligomers
  • Poisons
  • Alzheimer Disease
  • Toxicity
  17 Scopus citations

• Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows spinocerebellar ataxia type 1 phenotypes

  Lasagna-Reeves, C. A., Rousseaux, M. W. C., Guerrero-Munoz, M. J., Vilanova-Velez, L., Park, J., See, L., Jafar-Nejad, P., Richman, R., Orr, H. T., Kayed, R. & Zoghbi, H. Y., Dec 17 2015, In: eLife. 4, DECEMBER2015, e10891.

  Research output: Contribution to journal › Article › peer-review

  • Ataxin-1
  • Immunization
  • Oligomers
  • Spinocerebellar Ataxias
  • Passive Immunization
  9 Scopus citations

• Association of skin with the pathogenesis and treatment of neurodegenerative amyloidosis

  Clos, A. L., Kayed, R. & Lasagna-Reeves, C. A., 2012, In: Frontiers in Neurology. JAN, Article 5.

  Research output: Contribution to journal › Article › peer-review

  • Amyloidosis
  • Skin
  • Brain
  • Protein Aggregates
  • Amyloid Plaques
  10 Scopus citations

• Antibody against Small Aggregated Peptide Specifically Recognizes Toxic Aβ-42 Oligomers in Alzheimer's Disease

  Bodani, R. U., Sengupta, U., Castillo-Carranza, D. L., Guerrero-Muñoz, M. J., Gerson, J. E., Rudra, J. & Kayed, R., Dec 16 2015, In: ACS Chemical Neuroscience. 6, 12, p. 1981-1989 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Oligomers
  • Amyloid
  • Alzheimer Disease
  • Poisons
  • Peptides
  13 Scopus citations

• A native interactor scaffolds and stabilizes toxic Ataxin-1 oligomers in SCA1

  Lasagna-Reeves, C. A., Rousseaux, M. W. C., Guerrero-Munoz, M. J., Park, J., Jafar-Nejad, P., Richman, R., Lu, N., Sengupta, U., Litvinchuk, A., Orr, H. T., Kayed, R. & Zoghbi, H. Y., May 19 2015, In: eLife. 4, MAY, p. 1-46 46 p., e07558.

  Research output: Contribution to journal › Article › peer-review

  • Ataxin-1
  • Oligomers
  • Spinocerebellar Ataxias
  • Scaffolds
  • Drive
  16 Scopus citations

• Amyloid oligomer interactions and polymorphisms: disease-relevant distinct assembly of α-synuclein and tau

  Sengupta, U. & Kayed, R., Jan 1 2019, In: Neuropsychopharmacology. 44, 1, p. 222-223 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  1 Scopus citations

• Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

  Lasagna-Reeves, C. A., Castillo-Carranza, D. L., Sengupta, U., Guerrero-Munoz, M. J., Kiritoshi, T., Neugebauer, V., Jackson, G. R. & Kayed, R., 2012, In: Scientific reports. 2, 700.

  Research output: Contribution to journal › Article › peer-review

  • Pathology
  • Brain
  • Alzheimer Disease
  • Amyloid angiopathy
  • Genetically Modified Animals
  259 Scopus citations

• Advances in tau immunotherapy

  Gerson, J. & Kayed, R., Jan 1 2016, Research Progress in Alzheimer’s Disease and Dementia. Volume 6. Nova Science Publishers, Inc., p. 99-114 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Toxicity
  • Alzheimer's Disease
  • Protein
  • Vaccination
  • Antibody

• Advances and considerations in AD tau-targeted immunotherapy

  Bittar, A., Bhatt, N. & Kayed, R., Feb 2020, In: Neurobiology of Disease. 134, 104707.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Immunotherapy
  • Alzheimer Disease
  • tau Proteins
  • Amyloid
  • Direction compound
  15 Scopus citations

• AAV2-mediated GRP78 transfer alleviates retinal neuronal injury by downregulating ER stress and Tau oligomer formation

  Ha, Y., Liu, W., Liu, H., Zhu, S., Xia, F., Gerson, J. E., Azhar, N. A., Tilton, R. G., Motamedi, M., Kayed, R. & Zhang, W., Sep 2018, In: Investigative Ophthalmology and Visual Science. 59, 11, p. 4670-4682 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Nerve Crush
  • Retinal Ganglion Cells
  • Endoplasmic Reticulum Stress
  • Optic Nerve
  • Down-Regulation
  6 Scopus citations