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• Topoisomerase II inhibitors induce DNA damage-dependent interferon responses circumventing ebola virus immune evasion

  Luthra, P., Aguirre, S., Yen, B. C., Pietzsch, C. A., Sanchez-Aparicio, M. T., Tigabu, B., Morlock, L. K., García-Sastre, A., Leung, D. W., Williams, N. S., Fernandez-Sesma, A., Bukreyev, A. & Basler, C. F., Mar 1 2017, In: mBio. 8, 2, e00368-17.

  Research output: Contribution to journal › Article › peer-review

  • Topoisomerase II Inhibitors
  • Ebolavirus
  • Immune Evasion
  • Interferons
  • DNA Damage
  36 Scopus citations

• Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation

  Rialdi, A., Campisi, L., Zhao, N., Lagda, A. C., Pietzsch, C., Ho, J. S. Y., Martinez-Gil, L., Fenouil, R., Chen, X., Edwards, M., Metreveli, G., Jordan, S., Peralta, Z., Munoz-Fontela, C., Bouvier, N., Merad, M., Jin, J., Weirauch, M., Heinz, S., Benner, C. & 5 others, Van Bakel, H., Basler, C., García-Sastre, A., Bukreyev, A. & Marazzi, I., May 27 2016, In: Science. 352, 6289, 7993.

  Research output: Contribution to journal › Article › peer-review

  • Microbial Genes
  • Ebolavirus
  • Gene Expression
  • Inflammation
  • RNA Polymerase II
  65 Scopus citations

• The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding

  King, L. B., Fusco, M. L., Flyak, A. I., Ilinykh, P. A., Huang, K., Gunn, B., Kirchdoerfer, R. N., Hastie, K. M., Sangha, A. K., Meiler, J., Alter, G., Bukreyev, A., Crowe, J. E. & Saphire, E. O., Jan 10 2018, In: Cell Host and Microbe. 23, 1, p. 101-109.e4

  Research output: Contribution to journal › Article › peer-review

  • Marburgvirus
  • Virus Receptors
  • Virus Attachment
  • Monoclonal Antibodies
  • Glycoproteins
  11 Scopus citations

• The Ebola Interferon Inhibiting Domains Attenuate and Dysregulate Cell-Mediated Immune Responses

  Lubaki, N. M., Younan, P., Santos, R. I., Meyer, M., Iampietro, M., Koup, R. A. & Bukreyev, A., Dec 8 2016, In: PLoS pathogens. 12, 12, e1006031.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Interferons
  • Ebola Hemorrhagic Fever
  • Cytomegalovirus
  • Dendritic Cells
  21 Scopus citations

• Taxonomy of the order Mononegavirales: second update 2018

  Maes, P., Amarasinghe, G. K., Ayllón, M. A., Basler, C. F., Bavari, S., Blasdell, K. R., Briese, T., Brown, P. A., Bukreyev, A., Balkema-Buschmann, A., Buchholz, U. J., Chandran, K., Crozier, I., de Swart, R. L., Dietzgen, R. G., Dolnik, O., Domier, L. L., Drexler, J. F., Dürrwald, R., Dundon, W. G. & 57 others, Duprex, W. P., Dye, J. M., Easton, A. J., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freitas-Astúa, J., Ghedin, E., Griffiths, A., Hewson, R., Horie, M., Hurwitz, J. L., Hyndman, T. H., Jiāng, D., Kobinger, G. P., Kondō, H., Kurath, G., Kuzmin, I. V., Lamb, R. A., Lee, B., Leroy, E. M., Lǐ, J., Marzano, S. Y. L., Mühlberger, E., Netesov, S. V., Nowotny, N., Palacios, G., Pályi, B., Pawęska, J. T., Payne, S. L., Rima, B. K., Rota, P., Rubbenstroth, D., Simmonds, P., Smither, S. J., Song, Q., Song, T., Spann, K., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., van den Hoogen, B., Vasilakis, N., Wahl, V., Walker, P. J., Wang, D., Wang, L. F., Whitfield, A. E., Williams, J. V., Yè, G., Zerbini, F. M., Zhang, Y. Z. & Kuhn, J. H., Apr 3 2019, In: Archives of virology. 164, 4, p. 1233-1244 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mononegavirales
  • Viruses
  38 Scopus citations

• Taxonomy of the order Mononegavirales: update 2019

  Amarasinghe, G. K., Ayllón, M. A., Bào, Y., Basler, C. F., Bavari, S., Blasdell, K. R., Briese, T., Brown, P. A., Bukreyev, A., Balkema-Buschmann, A., Buchholz, U. J., Chabi-Jesus, C., Chandran, K., Chiapponi, C., Crozier, I., de Swart, R. L., Dietzgen, R. G., Dolnik, O., Drexler, J. F., Dürrwald, R. & 64 others, Dundon, W. G., Duprex, W. P., Dye, J. M., Easton, A. J., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freitas-Astúa, J., Griffiths, A., Hewson, R., Horie, M., Hyndman, T. H., Jiāng, D., Kitajima, E. W., Kobinger, G. P., Kondō, H., Kurath, G., Kuzmin, I. V., Lamb, R. A., Lavazza, A., Lee, B., Lelli, D., Leroy, E. M., Lǐ, J., Maes, P., Marzano, S. Y. L., Moreno, A., Mühlberger, E., Netesov, S. V., Nowotny, N., Nylund, A., Økland, A. L., Palacios, G., Pályi, B., Pawęska, J. T., Payne, S. L., Prosperi, A., Ramos-González, P. L., Rima, B. K., Rota, P., Rubbenstroth, D., Shī, M., Simmonds, P., Smither, S. J., Sozzi, E., Spann, K., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., van den Hoogen, B., Vasilakis, N., Wahl, V., Walker, P. J., Wang, L. F., Whitfield, A. E., Williams, J. V., Zerbini, F. M., Zhāng, T., Zhang, Y. Z. & Kuhn, J. H., Jul 1 2019, In: Archives of virology. 164, 7, p. 1967-1980 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mononegavirales
  • Viruses
  70 Scopus citations

• Taxonomy of the order Mononegavirales: update 2018

  Amarasinghe, G. K., Aréchiga Ceballos, N. G., Banyard, A. C., Basler, C. F., Bavari, S., Bennett, A. J., Blasdell, K. R., Briese, T., Bukreyev, A., Caì, Y., Calisher, C. H., Campos Lawson, C., Chandran, K., Chapman, C. A., Chiu, C. Y., Choi, K. S., Collins, P. L., Dietzgen, R. G., Dolja, V. V., Dolnik, O. & 71 others, Domier, L. L., Dürrwald, R., Dye, J. M., Easton, A. J., Ebihara, H., Echevarría, J. E., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freuling, C. M., Ghedin, E., Goldberg, T. L., Hewson, R., Horie, M., Hyndman, T. H., Jiāng, D., Kityo, R., Kobinger, G. P., Kondō, H., Koonin, E. V., Krupovic, M., Kurath, G., Lamb, R. A., Lee, B., Leroy, E. M., Maes, P., Maisner, A., Marston, D. A., Mor, S. K., Müller, T., Mühlberger, E., Ramírez, V. M. N., Netesov, S. V., Ng, T. F. F., Nowotny, N., Palacios, G., Patterson, J. L., Pawęska, J. T., Payne, S. L., Prieto, K., Rima, B. K., Rota, P., Rubbenstroth, D., Schwemmle, M., Siddell, S., Smither, S. J., Song, Q., Song, T., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Thomazelli, L. M., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Vázquez-Morón, S., Verdugo, C., Volchkov, V. E., Wahl, V., Walker, P. J., Wang, D., Wang, L. F., Wellehan, J. F. X., Wiley, M. R., Whitfield, A. E., Wolf, Y. I., Yè, G., Zhāng, Y. Z. & Kuhn, J. H., Aug 1 2018, In: Archives of virology. 163, 8, p. 2283-2294 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Mononegavirales
  • Viruses
  89 Scopus citations

• Taxonomy of the order Mononegavirales: update 2016

  Afonso, C. L., Amarasinghe, G. K., Bányai, K., Bào, Y., Basler, C. F., Bavari, S., Bejerman, N., Blasdell, K. R., Briand, F. X., Briese, T., Bukreyev, A., Calisher, C. H., Chandran, K., Chéng, J., Clawson, A. N., Collins, P. L., Dietzgen, R. G., Dolnik, O., Domier, L. L., Dürrwald, R. & 63 others, Dye, J. M., Easton, A. J., Ebihara, H., Farkas, S. L., Freitas-Astúa, J., Formenty, P., Fouchier, R. A. M., Fù, Y., Ghedin, E., Goodin, M. M., Hewson, R., Horie, M., Hyndman, T. H., Jiāng, D., Kitajima, E. W., Kobinger, G. P., Kondo, H., Kurath, G., Lamb, R. A., Lenardon, S., Leroy, E. M., Li, C. X., Lin, X. D., Liú, L., Longdon, B., Marton, S., Maisner, A., Mühlberger, E., Netesov, S. V., Nowotny, N., Patterson, J. L., Payne, S. L., Paweska, J. T., Randall, R. E., Rima, B. K., Rota, P., Rubbenstroth, D., Schwemmle, M., Shi, M., Smither, S. J., Stenglein, M. D., Stone, D. M., Takada, A., Terregino, C., Tesh, R. B., Tian, J. H., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Verbeek, M., Volchkov, V. E., Wahl-Jensen, V., Walsh, J. A., Walker, P. J., Wang, D., Wang, L. F., Wetzel, T., Whitfield, A. E., Xiè, J., Yuen, K. Y., Zhang, Y. Z. & Kuhn, J. H., Aug 1 2016, In: Archives of virology. 161, 8, p. 2351-2360 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Mononegavirales
  • Pneumovirinae
  • Aprepitant
  • Viruses
  268 Scopus citations

• Taxonomy of the order Mononegavirales: update 2017

  Amarasinghe, G. K., Bào, Y., Basler, C. F., Bavari, S., Beer, M., Bejerman, N., Blasdell, K. R., Bochnowski, A., Briese, T., Bukreyev, A., Calisher, C. H., Chandran, K., Collins, P. L., Dietzgen, R. G., Dolnik, O., Dürrwald, R., Dye, J. M., Easton, A. J., Ebihara, H., Fang, Q. & 53 others, Formenty, P., Fouchier, R. A. M., Ghedin, E., Harding, R. M., Hewson, R., Higgins, C. M., Hong, J., Horie, M., James, A. P., Jiāng, D., Kobinger, G. P., Kondo, H., Kurath, G., Lamb, R. A., Lee, B., Leroy, E. M., Li, M., Maisner, A., Mühlberger, E., Netesov, S. V., Nowotny, N., Patterson, J. L., Payne, S. L., Paweska, J. T., Pearson, M. N., Randall, R. E., Revill, P. A., Rima, B. K., Rota, P., Rubbenstroth, D., Schwemmle, M., Smither, S. J., Song, Q., Stone, D. M., Takada, A., Terregino, C., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Volchkov, V. E., Wahl-Jensen, V., Walker, P. J., Wang, B., Wang, D., Wang, F., Wang, L. F., Werren, J. H., Whitfield, A. E., Yan, Z., Ye, G. & Kuhn, J. H., Aug 1 2017, In: Archives of virology. 162, 8, p. 2493-2504 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Mononegavirales
  • Names
  • Pneumovirus
  • Rhabdoviridae
  • Viruses
  135 Scopus citations

• Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition

  Lin, X., Ammosova, T., Choy, M. S., Pietzsch, C. A., Ivanov, A., Ahmad, A., Saygideğer, Y., Kumari, N., Kovalskyy, D., Üren, A., Peti, W., Bukreyev, A. & Nekhai, S., Sep 13 2019, In: Frontiers in Microbiology. 10, 2145.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ebolavirus
  • Protein Phosphatase 1
  • ebola virus VP30 protein
  • Paintings
  • Virus Replication
  3 Scopus citations

• Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

  the Viral Hemorrhagic Fever Immunotherapeutic Consortium, Aug 9 2018, In: Cell. 174, 4, p. 938-952.e13

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Viruses
  • Glycoproteins
  • Monoclonal Antibodies
  • Assays
  68 Scopus citations

• Structural basis of broad ebolavirus neutralization by a human survivor antibody

  West, B. R., Wec, A. Z., Moyer, C. L., Fusco, M. L., Ilinykh, P. A., Huang, K., Wirchnianski, A. S., James, R. M., Herbert, A. S., Hui, S., Goodwin, E., Howell, K. A., Kailasan, S., Aman, M. J., Walker, L. M., Dye, J. M., Bukreyev, A., Chandran, K. & Saphire, E. O., Mar 1 2019, In: Nature Structural and Molecular Biology. 26, 3, p. 204-212 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Sudan
  • Viruses
  • Epitopes
  • Antibodies
  8 Scopus citations

• Staufen1 interacts with multiple components of the ebola virus ribonucleoprotein and enhances viral RNA synthesis

  Fang, J., Pietzsch, C., Ramanathan, P., Santos, R. I., Ilinykh, P. A., Garcia-Blanco, M. A., Bukreyev, A. & Bradrick, S. S., Sep 1 2018, In: mBio. 9, 5, e01771-18.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Ribonucleoproteins
  • Viral RNA
  • Nucleoproteins
  • RNA-Binding Proteins
  6 Scopus citations

• Role of Transmembrane Protein 16F in the Incorporation of Phosphatidylserine into Budding Ebola Virus Virions

  Younan, P., Iampietro, M., Santos, R. I., Ramanathan, P., Popov, V. L. & Bukreyev, A., Nov 22 2018, In: Journal of Infectious Diseases. 218, p. S335-S345

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Phosphatidylserines
  • Virion
  • Proteins
  • Viral Tropism
  3 Scopus citations

• Proteoform-specific insights into cellular proteome regulation

  Norris, E. L., Headlam, M. J., Dave, K. A., Smith, D. D., Bukreyev, A., Singh, T., Jayakody, B. A., Chappell, K. J., Collins, P. L. & Gorman, J. J., Oct 2016, In: Molecular and Cellular Proteomics. 15, 10, p. 3297-3320 24 p.

  Research output: Contribution to journal › Article › peer-review

  • Human respiratory syncytial virus
  • Viruses
  • Proteome
  • Proteolysis
  • Host Microbial Interactions
  2 Scopus citations

• Protein Phosphatase 1-Targeting Small-Molecule C31 Inhibits Ebola Virus Replication

  Ammosova, T., Pietzsch, C. A., Saygideǧer, Y., Ilatovsky, A., Lin, X., Ivanov, A., Kumari, N., Jerebtsova, M., Kulkarni, A., Petukhov, M., Üren, A., Bukreyev, A. & Nekhai, S., Nov 22 2018, In: Journal of Infectious Diseases. 218, p. S627-S635

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Protein Phosphatase 1
  • Virus Replication
  • 1E7-03 compound
  • Ebola Hemorrhagic Fever
  4 Scopus citations

• Possibility and challenges of conversion of current virus species names to Linnaean binomials

  Postler, T. S., Clawson, A. N., Amarasinghe, G. K., Basler, C. F., Bavari, S., Benko, M., Blasdell, K. R., Briese, T., Buchmeier, M. J., Bukreyev, A., Calisher, C. H., Chandran, K., Charrel, R., Clegg, C. S., Collins, P. L., De La Torre, J. C., DeRisi, J. L., Dietzgen, R. G., Dolnik, O., Dürrwald, R. & 52 others, Dye, J. M., Easton, A. J., Emonet, S., Formenty, P., Fouchier, R. A. M., Ghedin, E., Gonzalez, J. P., Harrach, B., Hewson, R., Horie, M., Jiāng, D., Kobinger, G., Kondo, H., Kropinski, A. M., Krupovic, M., Kurath, G., Lamb, R. A., Leroy, E. M., Lukashevich, I. S., Maisner, A., Mushegian, A. R., Netesov, S. V., Nowotny, N., Patterson, J. L., Payne, S. L., Paweska, J. T., Peters, C. J., Radoshitzky, S. R., Rima, B. K., Romanowski, V., Rubbenstroth, D., Sabanadzovic, S., Sanfaçon, H., Salvato, M. S., Schwemmle, M., Smither, S. J., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Volchkov, V. E., Wahl-Jensen, V., Walker, P. J., Wang, L. F., Varsani, A., Whitfield, A. E., Murilo Zerbini, F. & Kuhn, J. H., May 1 2017, In: Systematic Biology. 66, 3, p. 463-473 11 p.

  Research output: Contribution to journal › Article › peer-review

  • virus
  • Names
  • Mononegavirales
  • Arenaviridae
  • Viruses
  11 Scopus citations

• Phosphorylated VP30 of marburg virus is a repressor of transcription

  Tigabu, B., Ramanathan, P., Ivanov, A., Lin, X., Ilinykh, P. A., Parry, C. S., Freiberg, A. N., Nekhai, S. & Bukreyev, A., Nov 1 2018, In: Journal of virology. 92, 21, e00426.

  Research output: Contribution to journal › Article › peer-review

  • Marburg virus
  • Marburgvirus
  • phosphorylation
  • Phosphorylation
  • Ebolavirus
  7 Scopus citations

• Partial attenuation of respiratory syncytial virus with a deletion of a small hydrophobic gene is associated with elevated interleukin-1β responses

  Russell, R. F., McDonald, J. U., Ivanova, M., Zhong, Z., Bukreyev, A. & Tregoning, J. S., 2015, In: Journal of virology. 89, 17, p. 8974-8981 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory syncytial virus
  • interleukin-1
  • Respiratory Syncytial Viruses
  • Interleukin-1
  • Genes
  34 Scopus citations

• Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein

  Gilchuk, P., Kuzmina, N., Ilinykh, P. A., Huang, K., Gunn, B. M., Bryan, A., Davidson, E., Doranz, B. J., Turner, H. L., Fusco, M. L., Bramble, M. S., Hoff, N. A., Binshtein, E., Kose, N., Flyak, A. I., Flinko, R., Orlandi, C., Carnahan, R., Parrish, E. H., Sevy, A. M. & 12 others, Bombardi, R. G., Singh, P. K., Mukadi, P., Muyembe-Tamfum, J. J., Ohi, M. D., Saphire, E. O., Lewis, G. K., Alter, G., Ward, A. B., Rimoin, A. W., Bukreyev, A. & Crowe, J. E., Aug 21 2018, In: Immunity. 49, 2, p. 363-374.e10

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Glycoproteins
  • Antibodies
  • Monoclonal Antibodies
  • Viruses
  20 Scopus citations

• Modified mRNA-Based Vaccines Elicit Robust Immune Responses and Protect Guinea Pigs from Ebola Virus Disease

  Meyer, M., Huang, E., Yuzhakov, O., Ramanathan, P., Ciaramella, G. & Bukreyev, A., Jan 17 2018, In: Journal of Infectious Diseases. 217, 3, p. 451-455 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ebola Hemorrhagic Fever
  • Guinea Pigs
  • Vaccines
  • Messenger RNA
  • Ebola virus envelope glycoprotein
  29 Scopus citations

• Mechanism of Human Antibody-Mediated Neutralization of Marburg Virus

  Flyak, A. I., Ilinykh, P. A., Murin, C. D., Garron, T., Shen, X., Fusco, M. L., Hashiguchi, T., Bornholdt, Z. A., Slaughter, J. C., Sapparapu, G., Klages, C., Ksiazek, T. G., Ward, A. B., Saphire, E. O., Bukreyev, A. & Crowe, J. E., Feb 26 2015, In: Cell. 160, 5, p. 893-903 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Marburgvirus
  • Viruses
  • Glycoproteins
  • Neutralizing Antibodies
  • Antibodies
  89 Scopus citations

• Innate immune responses of bat and human cells to filoviruses: Commonalities and distinctions

  Kuzmin, I. V., Schwarz, T. M., Ilinykh, P. A., Jordan, I., Ksiazek, T. G., Sachidanandam, R., Basler, C. F. & Bukreyev, A., Apr 1 2017, In: Journal of virology. 91, 8, e02471-16.

  Research output: Contribution to journal › Article › peer-review

  • Filoviridae
  • Chiroptera
  • interferons
  • innate immunity
  • Innate Immunity
  25 Scopus citations

• Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses

  Luthra, P., Naidoo, J., Pietzsch, C. A., De, S., Khadka, S., Anantpadma, M., Williams, C. G., Edwards, M. R., Davey, R. A., Bukreyev, A., Ready, J. M. & Basler, C. F., Oct 2018, In: Antiviral research. 158, p. 288-302 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • pyrimidine
  • Nucleosides
  • Virus Replication
  • Innate Immunity
  24 Scopus citations

• Implementation of objective PASC-derived taxon demarcation criteria for official classification of filoviruses

  Bào, Y., Amarasinghe, G. K., Basler, C. F., Bavari, S., Bukreyev, A., Chandran, K., Dolnik, O., Dye, J. M., Ebihara, H., Formenty, P., Hewson, R., Kobinger, G. P., Leroy, E. M., Mühlberger, E., Netesov, S. V., Patterson, J. L., Paweska, J. T., Smither, S. J., Takada, A., Towner, J. S. & 3 others, Volchkov, V. E., Wahl-Jensen, V. & Kuhn, J. H., May 11 2017, In: Viruses. 9, 5, 106.

  Research output: Contribution to journal › Letter › peer-review

  • Filoviridae
  • Genome
  • Software Design
  • Information Centers
  • Nucleic Acid Databases
  9 Scopus citations

• ICTV virus taxonomy profile: Filoviridae

  ICTV Report Consortium, Jun 2019, In: Journal of General Virology. 100, 6, p. 911-912 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Filoviridae
  • Viruses
  • Marburgvirus
  • Ebolavirus
  • Chiroptera
  12 Scopus citations

• High-Throughput Minigenome System for Identifying Small-Molecule Inhibitors of Ebola Virus Replication

  Edwards, M. R., Pietzsch, C., Vausselin, T., Shaw, M. L., Bukreyev, A. & Basler, C. F., Jan 8 2016, In: ACS Infectious Diseases. 1, 8, p. 380-387 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Virus Replication
  • High-Throughput Screening Assays
  • Filoviridae
  • Inosine Monophosphate
  37 Scopus citations

• Ebola Virus Shed Glycoprotein Triggers Differentiation, Infection, and Death of Monocytes Through Toll-Like Receptor 4 Activation

  Iampietro, M., Santos, R. I., Lubaki, N. M. & Bukreyev, A., Nov 22 2018, In: Journal of Infectious Diseases. 218, p. S327-S334

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Ebola Vaccines
  • Toll-Like Receptor 4
  • Glycoproteins
  • Monocytes
  3 Scopus citations

• Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection

  Younan, P., Santos, R. I., Ramanathan, P., Iampietro, M., Nishida, A., Dutta, M., Ammosova, T., Meyer, M., Katze, M. G., Popov, V. L., Nekhai, S. & Bukreyev, A., 2019, In: PLoS pathogens. 15, 10, e1008068.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lymphocyte Depletion
  • Ebolavirus
  • T-Lymphocytes
  • Ebola Hemorrhagic Fever
  • Viral Antigens
  5 Scopus citations

• Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection

  Iampietro, M., Younan, P., Nishida, A., Dutta, M., Lubaki, N. M., Santos, R. I., Koup, R. A., Katze, M. G. & Bukreyev, A., May 2017, In: PLoS pathogens. 13, 5, e1006397.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Glycoproteins
  • T-Lymphocytes
  • Infection
  • Cell Death
  29 Scopus citations

• Ebolavirus Chimerization for the Development of a Mouse Model for Screening of Bundibugyo-Specific Antibodies

  Ilinykh, P. A., Graber, J., Kuzmina, N. A., Huang, K., Ksiazek, T. G., Crowe, J. E. & Bukreyev, A., Nov 22 2018, In: Journal of Infectious Diseases. 218, p. S418-S422

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Viruses
  • Antibodies
  • Monoclonal Antibodies
  • Knockout Mice
  1 Scopus citations

• Ebola virus binding to Tim-1 on T lymphocytes induces a cytokine storm

  Younan, P., Iampietro, M., Nishida, A., Ramanathan, P., Santos, R. I., Dutta, M., Lubaki, N. M., Koup, R. A., Katze, M. G. & Bukreyev, A., Sep 1 2017, In: mBio. 8, 5, e00845-17.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Virus Attachment
  • Cytokines
  • T-Lymphocytes
  • Ebola Hemorrhagic Fever
  41 Scopus citations

• Disruption of Phosphatidylserine Synthesis or Trafficking Reduces Infectivity of Ebola Virus

  Younan, P., Iampietro, M., Santos, R. I., Ramanathan, P., Popov, V. L. & Bukreyev, A., Nov 22 2018, In: Journal of Infectious Diseases. 218, p. S475-S485

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Phosphatidylserines
  • Virion
  • Cell Membrane
  • CDPdiacylglycerol-Serine O-Phosphatidyltransferase
  2 Scopus citations

• Disabling of lymphocyte immune response by Ebola virus

  Younan, P., Iampietro, M. & Bukreyev, A., Apr 2018, In: PLoS pathogens. 14, 4, e1006932.

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Different temporal effects of Ebola virus VP35 and VP24 proteins on global gene expression in human dendritic cells

  Ilinykh, P. A., Lubaki, N. M., Widen, S. G., Renn, L. A., Theisen, T. C., Rabin, R. L., Wood, T. G. & Bukreyev, A., 2015, In: Journal of virology. 89, 15, p. 7567-7583 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Ebola virus VP24 protein
  • filovirus VP35 protein
  • Ebolavirus
  • dendritic cells
  • Dendritic Cells
  32 Scopus citations

• Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk

  King, L. B., West, B. R., Moyer, C. L., Gilchuk, P., Flyak, A., Ilinykh, P. A., Bombardi, R., Hui, S., Huang, K., Bukreyev, A., Crowe, J. E. & Saphire, E. O., Dec 1 2019, In: Nature communications. 10, 1, 1788.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ebolavirus
  • viruses
  • antibodies
  • Viruses
  • Monoclonal Antibodies
  1 Scopus citations

• Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection

  Flyak, A. I., Shen, X., Murin, C. D., Turner, H. L., David, J. A., Fusco, M. L., Lampley, R., Kose, N., Ilinykh, P. A., Kuzmina, N., Branchizio, A., King, H., Brown, L., Bryan, C., Davidson, E., Doranz, B. J., Slaughter, J. C., Sapparapu, G., Klages, C., Ksiazek, T. G. & 4 others, Saphire, E. O., Ward, A. B., Bukreyev, A. & Crowe, J. E., Jan 28 2016, In: Cell. 164, 3, p. 392-405 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Viruses
  • Neutralizing Antibodies
  • Antibody Formation
  • Infection
  102 Scopus citations

• Corrigendum: Ebola VP40 in exosomes can cause immune cell dysfunction [Front. Microbiol., 7, (2016), (1765)] doi: 10.3389/fmicb.2016.01765

  Pleet, M. L., Mathiesen, A., DeMarino, C., Akpamagbo, Y. A., Barclay, R. A., Schwab, A., Iordanskiy, S., Sampey, G. C., Lepene, B., Ilinykh, P. A., Bukreyev, A., Nekhai, S., Aman, M. J. & Kashanchi, F., Apr 17 2018, In: Frontiers in Microbiology. 9, APR, 692.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Exosomes
  • Virion
  • Proteomics
  • Cyclin-Dependent Kinase 2
  • Mass Spectrometry
  1 Scopus citations

• Chimeric filoviruses for identification and characterization of monoclonal antibodies

  Ilinykh, P. A., Shen, X., Flyak, A. I., Kuzmina, N., Ksiazek, T. G., Crowe, J. E. & Bukreyev, A., Apr 1 2016, In: Journal of virology. 90, 8, p. 3890-3901 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Filoviridae
  • monoclonal antibodies
  • Monoclonal Antibodies
  • Ebolavirus
  • Glycoproteins
  22 Scopus citations

• Can Ebola Virus Vaccines Have Universal Immune Correlates of protection?

  Meyer, M., Malherbe, D. C. & Bukreyev, A., Jan 2019, In: Trends in Microbiology. 27, 1, p. 8-16 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Ebola Vaccines
  • Ebolavirus
  • Vaccines
  • Clinical Trials
  • Disease Outbreaks
  7 Scopus citations

• Broadly neutralizing antibodies from human survivors target a conserved site in the ebola virus glycoprotein hr2-mper region

  Flyak, A. I., Kuzmina, N., Murin, C. D., Bryan, C., Davidson, E., Gilchuk, P., Gulka, C. P., Ilinykh, P. A., Shen, X., Huang, K., Ramanathan, P., Turner, H., Fusco, M. L., Lampley, R., Kose, N., King, H., Sapparapu, G., Doranz, B. J., Ksiazek, T. G., Wright, D. W. & 4 others, Saphire, E. O., Ward, A. B., Bukreyev, A. & Crowe, J. E., Jun 1 2018, In: Nature Microbiology. 3, 6, p. 670-677 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • ZMapp
  • Neutralizing Antibodies
  • Survivors
  • Glycoproteins
  27 Scopus citations

• Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap

  Ilinykh, P. A., Santos, R. I., Gunn, B. M., Kuzmina, N. A., Shen, X., Huang, K., Gilchuk, P., Flyak, A. I., Younan, P., Alter, G., Crowe, J. E. & Bukreyev, A., Aug 2018, In: PLoS pathogens. 14, 8, e1007204.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Polysaccharides
  • Antiviral Agents
  • Glycoproteins
  • Monoclonal Antibodies
  6 Scopus citations

• A Sensitive in Vitro High-Throughput Screen to Identify Pan-filoviral Replication Inhibitors Targeting the VP35-NP Interface

  Liu, G., Nash, P. J., Johnson, B., Pietzsch, C., Ilagan, M. X. G., Bukreyev, A., Basler, C. F., Bowlin, T. L., Moir, D. T., Leung, D. W. & Amarasinghe, G. K., Mar 10 2017, In: ACS Infectious Diseases. 3, 3, p. 190-198 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Nucleoproteins
  • Viral Proteins
  • Virus Replication
  • Disease Outbreaks
  12 Scopus citations

• Antibody Repertoires to the Same Ebola Vaccine Antigen Are Differentially Affected by Vaccine Vectors

  Meyer, M., Yoshida, A., Ramanathan, P., Saphire, E. O., Collins, P. L., Crowe, J. E., Samal, S. & Bukreyev, A., Aug 14 2018, In: Cell Reports. 24, 7, p. 1816-1829 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Ebola Vaccines
  • Vaccines
  • Antigens
  • Viruses
  • Antibodies
  2 Scopus citations

• Antibody-mediated protective mechanisms induced by a trivalent parainfluenza virus-vectored ebolavirus vaccine

  Brian Kimble, J., Malherbe, D. C., Meyer, M., Gunn, B. M., Karim, M. M., Ilinykh, P. A., Iampietro, M., Mohamed, K. S., Negi, S., Gilchuk, P., Huang, K., Wolf, Y. I., Braun, W., Crowe, J. E., Alter, G. & Bukreyev, A., Feb 1 2019, In: Journal of virology. 93, 4, e0184518.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Paramyxoviridae Infections
  • vaccines
  • Zaire Ebola virus
  • Vaccines
  1 Scopus citations

• Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors

  Kuzmina, N. A., Younan, P., Gilchuk, P., Santos, R. I., Flyak, A. I., Ilinykh, P. A., Huang, K., Lubaki, N. M., Ramanathan, P., Crowe, J. E. & Bukreyev, A., Aug 14 2018, In: Cell Reports. 24, 7, p. 1802-1815.e5

  Research output: Contribution to journal › Article › peer-review

  • Antibody-Dependent Enhancement
  • Ebola Hemorrhagic Fever
  • Viruses
  • Filoviridae Infections
  • Antibodies
  28 Scopus citations

• A high throughput screen identifies benzoquinoline compounds as inhibitors of Ebola virus replication

  Luthra, P., Liang, J., Pietzsch, C. A., Khadka, S., Edwards, M. R., Wei, S., De, S., Posner, B., Bukreyev, A., Ready, J. M. & Basler, C. F., Feb 2018, In: Antiviral research. 150, p. 193-201 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Virus Replication
  • Antiviral Agents
  • RNA Viruses
  • Filoviridae
  19 Scopus citations

• Aerosolized Ebola vaccine protects primates and elicits lung-resident T cell responses

  Meyer, M., Garron, T., Lubaki, N. M., Mire, C. E., Fenton, K. A., Klages, C., Olinger, G. G., Geisbert, T. W., Collins, P. L. & Bukreyev, A., Aug 3 2015, In: Journal of Clinical Investigation. 125, 8, p. 3241-3255 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Ebola Vaccines
  • Ebolavirus
  • Primates
  • Vaccines
  • Aerosols
  45 Scopus citations

• Adapting high-throughput screening methods and assays for biocontainment laboratories

  Rasmussen, L., Tigabu, B., White, E. L., Bostwick, R., Tower, N., Bukreyev, A., Rockx, B., Leduc, J. W. & Noah, J. W., Feb 1 2015, In: Assay and Drug Development Technologies. 13, 1, p. 44-54 11 p.

  Research output: Contribution to journal › Article › peer-review

  • High-Throughput Screening Assays
  • Containment of Biohazards
  • Drug Discovery
  • Nipah Virus
  • Ebolavirus
  5 Scopus citations