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Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin
Gundermann, D. M., Walker, D. K., Reidy, P. T., Borack, M. S., Dickinson, J. M., Volpi, E. & Rasmussen, B. B., May 15 2014, In: American Journal of Physiology - Endocrinology and Metabolism. 306, 10, p. E1198-E1204Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism1-3
Glynn, E. L., Fry, C. S., Timmerman, K. L., Drummond, M. J., Volpi, E. & Rasmussen, B. B., Mar 2013, In: Journal of Nutrition. 143, 3, p. 307-314 8 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Aerobic exercise for treatment of sarcopenia: Targeting insulin resistance and endothelial dysfunction
Volpi, E., 2011, In: Japanese Journal of Physical Fitness and Sports Medicine. 60, 1, p. 38 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Age-related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation
Tanner, R. E., Brunker, L. B., Agergaard, J., Barrows, K. M., Briggs, R. A., Kwon, O. S., Young, L. M., Hopkins, P. N., Volpi, E., Marcus, R. L., Lastayo, P. C. & Drummond, M. J., Sep 1 2015, In: Journal of Physiology. 593, 18, p. 4259-4273 15 p.Research output: Contribution to journal › Article › peer-review
83 Scopus citations -
Aging and microRNA expression in human skeletal muscle: A microarray and bioinformatics analysis
Drummond, M. J., McCarthy, J. J., Sinha, M., Spratt, H. M., Volpi, E., Esser, K. A. & Rasmussen, B. B., May 2011, In: Physiological Genomics. 43, 10, p. 595-603 9 p.Research output: Contribution to journal › Article › peer-review
151 Scopus citations -
Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise
Dickinson, J. M., Drummond, M. J., Coben, J. R., Volpi, E. & Rasmussen, B. B., Apr 2013, In: Clinical Nutrition. 32, 2, p. 273-280 8 p.Research output: Contribution to journal › Article › peer-review
48 Scopus citations -
Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis
Fry, C. S., Drummond, M. J., Glynn, E. L., Dickinson, J. M., Gundermann, D. M., Timmerman, K. L., Walker, D. K., Dhanani, S., Volpi, E. & Rasmussen, B. B., Mar 2 2011, In: Skeletal Muscle. 1, 1, 11.Research output: Contribution to journal › Article › peer-review
202 Scopus citations -
A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults
Timmerman, K. L., Dhanani, S., Glynn, E. L., Fry, C. S., Drummond, M. J., Jennings, K., Rasmussen, B. B. & Volpi, E., Jun 1 2012, In: American Journal of Clinical Nutrition. 95, 6, p. 1403-1412 10 p.Research output: Contribution to journal › Article › peer-review
83 Scopus citations -
Androgen Therapy and Rehospitalization in Older Men with Testosterone Deficiency
Baillargeon, J., Deer, R. R., Kuo, Y. F., Zhang, D., Goodwin, J. S. & Volpi, E., May 1 2016, In: Mayo Clinic Proceedings. 91, 5, p. 587-595 9 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
A soy, whey and caseinate blend extends postprandial skeletal muscle protein synthesis in rats
Butteiger, D. N., Cope, M., Liu, P., Mukherjea, R., Volpi, E., Rasmussen, B. B. & Krul, E. S., Aug 2013, In: Clinical Nutrition. 32, 4, p. 585-591 7 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults
Drummond, M. J., Dickinson, J. M., Fry, C. S., Walker, D. K., Gundermann, D. M., Reidy, P. T., Timmerman, K. L., Markofski, M. M., Paddon-Jones, D., Rasmussen, B. B. & Volpi, E., May 1 2012, In: American Journal of Physiology - Endocrinology and Metabolism. 302, 9, p. E1113-E1122Research output: Contribution to journal › Article › peer-review
123 Scopus citations -
Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans
Chondronikola, M., Volpi, E., Børsheim, E., Porter, C., Saraf, M. K., Annamalai, P., Yfanti, C., Chao, T., Wong, D., Shinoda, K., Labbe, S. M., Hurren, N. M., Cesani, F., Kajimura, S. & Sidossis, L. S., Jun 14 2016, In: Cell Metabolism. 23, 6, p. 1200-1206 7 p.Research output: Contribution to journal › Article › peer-review
133 Scopus citations -
Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans
Chondronikola, M., Volpi, E., Børsheim, E., Porter, C., Annamalai, P., Enerbäck, S., Lidell, M. E., Saraf, M. K., Labbe, S. M., Hurren, N. M., Yfanti, C., Chao, T., Andersen, C. R., Cesani, F., Hawkins, H. & Sidossis, L. S., Dec 1 2014, In: Diabetes. 63, 12, p. 4089-4099 11 p.Research output: Contribution to journal › Article › peer-review
Open Access375 Scopus citations -
Brown adipose tissue is linked to a distinct thermoregulatory response to mild cold in people
Chondronikola, M., Volpi, E., Børsheim, E., Chao, T., Porter, C., Annamalai, P., Yfanti, C., Labbe, S. M., Hurren, N. M., Malagaris, I., Cesani, F. & Sidossis, L. S., Apr 19 2016, In: Frontiers in Physiology. 7, APR, 129.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Challenges and new opportunities for clinical nutrition interventions in the aged
Johnson, M. A., Dwyer, J. T., Jensen, G. L., Miller, J. W., Speakman, J. R., Starke-Reed, P. & Volpi, E., Mar 1 2011, In: Journal of Nutrition. 141, 3, p. 535-541 7 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Deficiency in Repair of the Mitochondrial Genome Sensitizes Proliferating Myoblasts to Oxidative Damage
Szczesny, B., Olah, G., Walker, D. K., Volpi, E., Rasmussen, B. B., Szabo, C. & Mitra, S., Sep 16 2013, In: PloS one. 8, 9, e75201.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women
Markofski, M. M., Dickinson, J. M., Drummond, M. J., Fry, C. S., Fujita, S., Gundermann, D. M., Glynn, E. L., Jennings, K., Paddon-Jones, D., Reidy, P. T., Sheffield-Moore, M., Timmerman, K. L., Rasmussen, B. B. & Volpi, E., May 1 2015, In: Experimental Gerontology. 65, p. 1-7 7 p.Research output: Contribution to journal › Article › peer-review
65 Scopus citations -
Efficacy and safety of leucine supplementation in the elderly
Borack, M. S. & Volpi, E., Dec 1 2016, In: Journal of Nutrition. 146, 12, p. 2625S-2629SResearch output: Contribution to journal › Article › peer-review
25 Scopus citations -
Endothelial function and the regulation of muscle protein anabolism in older adults
Timmerman, K. L. & Volpi, E., 2013, In: Nutrition, Metabolism and Cardiovascular Diseases. 23, SUPPL1, p. S44eS50Research output: Contribution to journal › Review article › peer-review
30 Scopus citations -
Evidence-based recommendations for optimal dietary protein intake in older people: A position paper from the prot-age study group
Bauer, J., Biolo, G., Cederholm, T., Cesari, M., Cruz-Jentoft, A. J., Morley, J. E., Phillips, S., Sieber, C., Stehle, P., Teta, D., Visvanathan, R., Volpi, E. & Boirie, Y., Aug 2013, In: Journal of the American Medical Directors Association. 14, 8, p. 542-559 18 p.Research output: Contribution to journal › Article › peer-review
921 Scopus citations -
Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle
Dickinson, J. M., Volpi, E. & Rasmussen, B. B., Oct 1 2013, In: Exercise and Sport Sciences Reviews. 41, 4, p. 216-223 8 p.Research output: Contribution to journal › Article › peer-review
68 Scopus citations -
Identifying effective and feasible interventions to accelerate functional recovery from hospitalization in older adults: A randomized controlled pilot trial
Deer, R. R., Dickinson, J. M., Fisher, S. R., Ju, H. & Volpi, E., Jul 1 2016, In: Contemporary Clinical Trials. 49, p. 6-14 9 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans
Glynn, E. L., Piner, L. W., Huffman, K. M., Slentz, C. A., Elliot-Penry, L., AbouAssi, H., White, P. J., Bain, J. R., Muehlbauer, M. J., Ilkayeva, O. R., Stevens, R. D., Porter Starr, K. N., Bales, C. W., Volpi, E., Brosnan, M. J., Trimmer, J. K., Rolph, T. P., Newgard, C. B. & Kraus, W. E., Aug 9 2015, In: Diabetologia. 58, 10, p. 2324-2335 12 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells
Walker, D. K., Drummond, M. J., Dickinson, J. M., Borack, M. S., Jennings, K., Volpi, E. & Rasmussen, B. B., Mar 2014, In: Physiological reports. 2, 3, e00238.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Is the optimal level of protein intake for older adults greater than the recommended dietary allowance?
Volpi, E., Campbell, W. W., Dwyer, J. T., Johnson, M. A., Jensen, G. L., Morley, J. E. & Wolfe, R. R., Jun 2013, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 68, 6, p. 677-681 5 p.Research output: Contribution to journal › Article › peer-review
201 Scopus citations -
Kyphoplasty for vertebral augmentation in the elderly with osteoporotic vertebral compression fractures: Scenarios and review of recent studies
Bednar, T., Heyde, C. E., Bednar, G., Nguyen, D., Volpi, E. & Przkora, R., Nov 2013, In: Clinical Therapeutics. 35, 11, p. 1721-1727 7 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Leucine-enriched Amino acid ingestion after resistance exercise prolongs myofibrillar protein synthesis and amino acid transporter expression in older men
Dickinson, J. M., Gundermann, D. M., Walker, D. K., Reidy, P. T., Borack, M. S., Drummond, M. J., Arora, M., Volpi, E. & Rasmussen, B. B., 2014, In: Journal of Nutrition. 144, 11, p. 1694-1702 9 p.Research output: Contribution to journal › Article › peer-review
56 Scopus citations -
Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids
Dickinson, J. M., Fry, C. S., Drummond, M. J., Gundermann, D. M., Walker, D. K., Glynn, E. L., Timmerman, K. L., Dhanani, S., Volpi, E. & Rasmussen, B. B., May 1 2011, In: Journal of Nutrition. 141, 5, p. 856-862 7 p.Research output: Contribution to journal › Article › peer-review
153 Scopus citations -
Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle
Porter, C., Hurren, N. M., Cotter, M. V., Bhattarai, N., Reidy, P. T., Dillon, E., Durham, W. J., Tuvdendorj, D., Sheffield-Moore, M., Volpi, E., Sidossis, L. S., Rasmussen, B. & Børsheim, E., Aug 5 2015, In: American Journal of Physiology - Endocrinology and Metabolism. 309, 3, p. E224-E232Research output: Contribution to journal › Article › peer-review
55 Scopus citations -
Muscle Biology and mTORC1 Signaling in Aging
Rasmussen, B. B. & Volpi, E., Jul 27 2012, Sarcopenia. John Wiley and Sons, p. 20-40 21 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Muscle Biology and mTORC1 Signaling in Aging
Rasmussen, B. B. & Volpi, E., 2012, Sarcopenia. Cruz-Jentoft, A. J. & Morley, J. E. (eds.). 1st ed. Wiley-Blackwell, p. 20-40Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Muscle protein metabolism responds similarly to exogenous amino acids in healthy younger and older adults during NO-induced hyperemia
Dillon, E. L., Casperson, S. L., Durham, W. J., Randolph, K. M., Urban, R. J., Volpi, E., Ahmad, M., Kinsky, M. P. & Sheffield-Moore, M., Nov 2011, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 301, 5, p. R1408-R1417Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
PAX7+ satellite cells in young and older adults following resistance exercise
Walker, D. K., Fry, C. S., Drummond, M. J., Dickinson, J. M., Timmerman, K. L., Gundermann, D. M., Jennings, K., Volpi, E. & Rasmussen, B. B., Jul 2012, In: Muscle and Nerve. 46, 1, p. 51-59 9 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Protein blend ingestion following resistance exercise promotes human muscle protein synthesis
Reidy, P. T., Walker, D. K., Dickinson, J. M., Gundermann, D. M., Drummond, M. J., Timmerman, K. L., Fry, C. S., Borack, M. S., Cope, M. B., Mukherjea, R., Jennings, K., Volpi, E. & Rasmussen, B. B., Apr 1 2013, In: Journal of Nutrition. 143, 4, p. 410-416 7 p.Research output: Contribution to journal › Article › peer-review
86 Scopus citations -
Protein intake and muscle function in older adults
Deer, R. R. & Volpi, E., May 27 2015, In: Current Opinion in Clinical Nutrition and Metabolic Care. 18, 3, p. 248-253 6 p.Research output: Contribution to journal › Review article › peer-review
75 Scopus citations -
Protein metabolism in women and men: Similarities and disparities
Markofski, M. M. & Volpi, E., Jan 2011, In: Current Opinion in Clinical Nutrition and Metabolic Care. 14, 1, p. 93-97 5 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Protein supplementation has minimal effects on muscle adaptations during resistance exercise training in young men: A double-blind randomized clinical trial
Reidy, P. T., Borack, M. S., Markofski, M. M., Dickinson, J. M., Deer, R. R., Husaini, S. H., Walker, D. K., Igbinigie, S., Robertson, S. M., Cope, M. B., Mukherjea, R., Hall-Porter, J. M., Jennings, K., Volpi, E. & Rasmussen, B. B., 2016, In: Journal of Nutrition. 146, 9, p. 1660-1669 10 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling
Matveyenko, A. V., Liuwantara, D., Gurlo, T., Kirakossian, D., Dalla Man, C., Cobelli, C., White, M. F., Copps, K. D., Volpi, E., Fujita, S. & Butler, P. C., Sep 2012, In: Diabetes. 61, 9, p. 2269-2279 11 p.Research output: Contribution to journal › Article › peer-review
81 Scopus citations -
Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle
Dickinson, J. M., Drummond, M. J., Fry, C. S., Gundermann, D. M., Walker, D. K., Timmerman, K. L., Volpi, E. & Rasmussen, B. B., Jan 2013, In: Metabolism: Clinical and Experimental. 62, 1, p. 144-151 8 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Reactive hyperemia is not responsible for stimulating muscle protein synthesis following blood flow restriction exercise
Gundermann, D. M., Fry, C. S., Dickinson, J. M., Walker, D. K., Timmerman, K. L., Drummond, M. J., Volpi, E. & Rasmussen, B. B., May 1 2012, In: Journal of Applied Physiology. 112, 9, p. 1520-1528 9 p.Research output: Contribution to journal › Article › peer-review
55 Scopus citations -
Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults
Drummond, M. J., Timmerman, K. L., Markofski, M. M., Walker, D. K., Dickinson, J. M., Jamaluddin, M., Brasier, A. R., Rasmussen, B. B. & Volpi, E., Aug 1 2013, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 305, 3, p. R216-R223Research output: Contribution to journal › Article › peer-review
59 Scopus citations -
Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise
Drummond, M. J., Fry, C. S., Glynn, E. L., Timmerman, K. L., Dickinson, J. M., Walker, D. K., Gundermann, D. M., Volpi, E. & Rasmussen, B. B., Jul 2011, In: Journal of Applied Physiology. 111, 1, p. 135-142 8 p.Research output: Contribution to journal › Article › peer-review
68 Scopus citations -
Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults
Fry, C. S., Drummond, M. J., Glynn, E. L., Dickinson, J. M., Gundermann, D. M., Timmerman, K. L., Walker, D. K., Volpi, E. & Rasmussen, B. B., May 2013, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 68, 5, p. 599-607 9 p.Research output: Contribution to journal › Article › peer-review
96 Scopus citations -
Soy-dairy protein blend and whey protein ingestion after resistance exercise increases amino acid transport and transporter expression in human skeletal muscle
Reidy, P. T., Walker, D. K., Dickinson, J. M., Gundermann, D. M., Drummond, M. J., Timmerman, K. L., Cope, M. B., Mukherjea, R., Jennings, K., Volpi, E. & Rasmussen, B. B., Jun 1 2014, In: Journal of Applied Physiology. 116, 11, p. 1353-1364 12 p.Research output: Contribution to journal › Article › peer-review
50 Scopus citations -
Soy-dairy protein blend or whey protein isolate ingestion induces similar postexercise muscle mechanistic target of rapamycin complex 1 signaling and protein synthesis responses in older men
Borack, M. S., Reidy, P. T., Husaini, S. H., Markofski, M. M., Deer, R. R., Richison, A. B., Lambert, B. S., Cope, M. B., Mukherjea, R., Jennings, K., Volpi, E. & Rasmussen, B. B., Dec 1 2016, In: Journal of Nutrition. 146, 12, p. 2468-2475 8 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Testing the effects of narrative and play on physical activity among breast cancer survivors using mobile apps: Study protocol for a randomized controlled trial
Lyons, E. J., Baranowski, T., Basen-Engquist, K. M., Lewis, Z. H., Swartz, M. C., Jennings, K. & Volpi, E., Mar 9 2016, In: BMC Cancer. 16, 1, 202.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Use of the short physical performance battery and step monitoring to evaluate improvements after epidural steroid injections in an elderly patient
Przkora, R., Fisher, S. R., Von Der Hoeh, N., Heyde, C. E., Dominguez, J. D., Maybauer, M. O. & Volpi, E., Jun 1 2015, In: Journal of Clinical Gerontology and Geriatrics. 6, 2, p. 68-70 3 p., 139.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Vitamin D and endothelial vasodilation in older individuals: Data from the PIVUS study
Maggio, M., De Vita, F., Lauretani, F., Ceda, G. P., Volpi, E., Giallauria, F., De Cicco, G., Cattabiani, C., Melhus, H., Michaëlsson, K., Cederholm, T. & Lind, L., Sep 1 2014, In: Journal of Clinical Endocrinology and Metabolism. 99, 9, p. 3382-3389 8 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations