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• Traumatic Brain Injury-Induced Dysregulation of the Circadian Clock

  Boone, D. R., Sell, S. L., Micci, M. A., Crookshanks, J. M., Parsley, M., Uchida, T., Prough, D. S., DeWitt, D. S. & Hellmich, H. L., Oct 3 2012, In: PloS one. 7, 10, e46204.

  Research output: Contribution to journal › Article › peer-review

  • Circadian Clocks
  • circadian clocks
  • Traumatic Brain Injury
  • Clocks
  • Brain
  47 Scopus citations

• Tau Oligomers Derived from Traumatic Brain Injury Cause Cognitive Impairment and Accelerate Onset of Pathology in Htau Mice

  Gerson, J., Castillo-Carranza, D. L., Sengupta, U., Bodani, R., Prough, D. S., DeWitt, D. S., Hawkins, B. E. & Kayed, R., Nov 15 2016, In: Journal of neurotrauma. 33, 22, p. 2034-2043 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Traumatic Brain Injury
  • Cognitive Dysfunction
  • Pathology
  • Brain
  • Neurodegenerative Diseases
  39 Scopus citations

• Stochastic fluctuations in gene expression in aging hippocampal neurons could be exacerbated by traumatic brain injury

  Shearer, J., Boone, D., Weisz, H., Jennings, K., Uchida, T., Parsley, M., DeWitt, D., Prough, D. & Hellmich, H., Apr 1 2016, In: Aging Clinical and Experimental Research. 28, 2, p. 363-367 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Traumatic Brain Injury
  • Neurons
  • Gene Expression
  • Cognitive Dysfunction
  • Cell Survival
  1 Scopus citations

• Proteomic changes in traumatic brain injury: Experimental approaches

  Sowers, J. L., Wu, P., Zhang, K., DeWitt, D. S. & Prough, D. S., 2018, In: Current opinion in neurology. 31, 6, p. 709-717 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Traumatic Brain Injury
  • Proteomics
  • Theoretical Models
  • Proteome
  • Mass Spectrometry
  4 Scopus citations

• Pre-clinical testing of therapies for traumatic brain injury

  DeWitt, D. S., Hawkins, B. E., Dixon, C. E., Kochanek, P. M., Armstead, W., Bass, C. R., Bramlett, H. M., Buki, A., Dietrich, W. D., Ferguson, A. R., Hall, E. D., Hayes, R. L., Hinds, S. R., Laplaca, M. C., Long, J. B., Meaney, D. F., Mondello, S., Noble-Haeusslein, L. J., Poloyac, S. M., Prough, D. S. & 8 others, Robertson, C. S., Saatman, K. E., Shultz, S. R., Shear, D. A., Smith, D. H., Valadka, A. B., Vandevord, P. & Zhang, L., Dec 1 2018, In: Journal of neurotrauma. 35, 23, p. 2737-2754 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Traumatic Brain Injury
  • Consensus
  • Research Personnel
  • Guidelines
  • Investigational Therapies
  35 Scopus citations

• Persistent Behavioral Deficits in Rats after Parasagittal Fluid Percussion Injury

  Sell, S., Johnson, K., Dewitt, D. & Prough, D., Mar 1 2017, In: Journal of Neurotrauma. 34, 5, p. 1086-1096 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Percussion
  • Traumatic Brain Injury
  • Wounds and Injuries
  • Memory Disorders
  • Short-Term Memory
  18 Scopus citations

• Nano-Pulsed Laser Therapy Is Neuroprotective in a Rat Model of Blast-Induced Neurotrauma

  Esenaliev, R. O., Petrov, I. Y., Petrov, Y., Guptarak, J., Boone, D. R., Mocciaro, E., Weisz, H., Parsley, M. A., Sell, S. L., Hellmich, H., Ford, J. M., Pogue, C., Dewitt, D., Prough, D. S. & Micci, M. A., Jul 2018, In: Journal of neurotrauma. 35, 13, p. 1510-1522 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Laser Therapy
  • Lasers
  • Caspase 3
  • Brain-Derived Neurotrophic Factor
  • Microglia
  13 Scopus citations

• Molecular mechanisms underlying effects of neural stem cells against traumatic axonal injury

  Wang, E., Gao, J., Yang, Q., Parsley, M. O., Dunn, T. J., Zhang, L., Dewitt, D. S., Denner, L., Prough, D. S. & Wu, P., Jan 20 2012, In: Journal of neurotrauma. 29, 2, p. 295-312 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Glial Cell Line-Derived Neurotrophic Factor
  • Neural Stem Cells
  • Traumatic Brain Injury
  • Wounds and Injuries
  • Actins
  22 Scopus citations

• Military Blast Exposure and Chronic Neurodegeneration: Summary of Working Groups and Expert Panel Findings and Recommendations

  Brix, K. A., Brody, D. L., Grimes, J. B., Yitzhak, A., Agoston, D., Aldag, M., Armstrong, R., Arun, P., Audette, M., Babcock, D., Balaban, C., Banton, R., Bellgowan, P., Borkholder, D., Broglio, S., Brokaw, E., Cantu, R., Carr, W., Chapman, S., Cmarik, J. & 96 others, Colder, B., Colombe, J., Cook, D., Cozzarelli, T., Da Silva, U. O., Daphalapurkar, N., Dardzinski, B., DeGraba, T., DeMar, J., DeWitt, D., Dickstein, D., Duckworth, J., Elder, G., Fazel-Rezai, R., Fine, M., Fiskum, G., Fournier, A., Ganpule, S., Gill, J., Glenn, J. F., Greene, C., Greig, N., Haering, C., Harrington, J., Hein, A., Helmick, K., Hicks, R., Hinds, S., Hoffman, S., Horkayne-Szakaly, I., Iacono, D., Ishii, E., Jones, R. V., Karami, G., Krawczyk, D., Labutta, R., Latta, R., Lattimore, T., Leggieri, M., Leonessa, F., Lin, A., Ling, G., Long, M., Lu, K. P., Panker, S. M., McCabe, J., Merkle, A., Montenigro, P., Mueller, G. P., Ng, L., Nigam, S., O'Donnell, J., Okonkwo, D., Pauli, I., Perl, D., Peskind, E., Pfister, B., Philippens, M., Piehler, T., Proctor, J., Przekwas, A., Qashu, F., Raskind, M., Razumovsky, A., Reifman, J., Reyes, P., Rigby, P., Risling, M., Robinson, M., Rooks, T., Rosen, C., Rosseau, G., Sammons-Jackson, W., Santago, A., Shoge, R., Sours, C., Stone, J., Templin, M., Tepe, V., Thielen, P., Thomas, M., Timmes, T., Tortella, F., Tucker, L., Tweedie, D., Hamm, D. V., Christie Vu, B., Wang, Y., West, T., Wilde, E., Willis, A., Wu, J., Zai, L., Zander, N., Zheng, J. & Ziejewski, M., Sep 2017, In: Journal of neurotrauma. 34, S1, p. S18-S25

  Research output: Contribution to journal › Article › peer-review

  • Chronic Traumatic Encephalopathy
  • Traumatic Brain Injury
  • Sports
  • Blast Injuries
  • Neuropathology
  7 Scopus citations

• MicroRNA sequencing of rat hippocampus and human biofluids identifies acute, chronic, focal and diffuse traumatic brain injuries

  Weisz, H. A., Kennedy, D., Widen, S., Spratt, H., Sell, S. L., Bailey, C., Sheffield-Moore, M., DeWitt, D. S., Prough, D. S., Levin, H., Robertson, C. & Hellmich, H. L., Dec 1 2020, In: Scientific reports. 10, 1, 3341.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Diffuse Brain Injury
  • Traumatic Brain Injury
  • MicroRNAs
  • Hippocampus
  • Circulating MicroRNA

• Introduction to the Special Issue on Translation

  Dewitt, D. & Prough, D. S., Nov 15 2020, In: Journal of neurotrauma. 37, 22, p. 2351-2352 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• Influence of stochastic gene expression on the cell survival rheostat after traumatic brain injury

  Rojo, D. R., Prough, D. S., Falduto, M. T., Boone, D. R., Micci, M. A., Kahrig, K. M., Crookshanks, J. M., Jimenez, A., Uchida, T., Cowart, J. C., Hawkins, B. E., Avila, M., DeWitt, D. S. & Hellmich, H. L., 2011, In: PloS one. 6, 8, e23111.

  Research output: Contribution to journal › Article › peer-review

  • Gene expression
  • Traumatic Brain Injury
  • Cells
  • cell viability
  • Neurons
  24 Scopus citations

• Inflammatory cytokine receptor blockade in a rodent model of mild traumatic brain injury

  Perez-Polo, J. R., Rea, H. C., Johnson, K. M., Parsley, M. A., Unabia, G. C., Xu, G. Y., Prough, D., Dewitt, D. S., Paulucci-Holthauzen, A. A., Werrbach-Perez, K. & Hulsebosch, C. E., Jan 2016, In: Journal of Neuroscience Research. 94, 1, p. 27-38 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Brain Concussion
  • Cytokine Receptors
  • Interleukin 1 Receptor Antagonist Protein
  • Rodentia
  • Tumor Necrosis Factor-alpha
  10 Scopus citations

• Impact & blast traumatic brain injury: Implications for therapy

  Yamamoto, S., DeWitt, D. S. & Prough, D. S., 2018, In: Molecules. 23, 2, 245.

  Research output: Contribution to journal › Review article › peer-review

  • brain damage
  • blasts
  • Traumatic Brain Injury
  • therapy
  • Brain
  13 Scopus citations

• Identification of agents that reduce renal hypoxia-reoxygenation injury using cell-based screening: Purine nucleosides are alternative energy sources in LLC-PK1 cells during hypoxia

  Szoleczky, P., Módis, K., Nagy, N., Dóri Tóth, Z., Dewitt, D., Szabó, C. & Gero, D., Jan 1 2012, In: Archives of Biochemistry and Biophysics. 517, 1, p. 53-70 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Renal Agents
  • LLC-PK1 Cells
  • Purine Nucleosides
  • Cell Hypoxia
  • Cell death
  19 Scopus citations

• Human neural stem cell transplantation-mediated alteration of microglial/macrophage phenotypes after traumatic brain injury

  Gao, J., Grill, R. J., Dunn, T. J., Bedi, S., Labastida, J. A., Hetz, R. A., Xue, H., Thonhoff, J. R., Dewitt, D. S., Prough, D. S., Cox, C. S. & Wu, P., 2016, In: Cell Transplantation. 25, 10, p. 1863-1877 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Macrophages
  • Stem cells
  • Microglia
  • Neural Stem Cells
  • Stem Cell Transplantation
  23 Scopus citations

• Galveston brain injury conference 2010: Clinical and experimental aspects of blast injury

  Masel, B. E., Bell, R. S., Brossart, S., Grill, R. J., Hayes, R. L., Levin, H. S., Rasband, M. N., Ritzel, D. V., Wade, C. E. & Dewitt, D. S., Aug 10 2012, In: Journal of neurotrauma. 29, 12, p. 2143-2171 29 p.

  Research output: Contribution to journal › Article › peer-review

  • Blast Injuries
  • Congresses
  • Brain Injuries
  • Theoretical Models
  • Afghan Campaign 2001-
  26 Scopus citations

• Fluorophilia: Fluorophore-containing compounds adhere non-specifically to injured neurons

  Hawkins, B. E., Frederickson, C. J., Dewitt, D. S. & Prough, D. S., Jan 13 2012, In: Brain Research. 1432, p. 28-35 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Fluorescein
  • Coloring Agents
  • Neurons
  • Staining and Labeling
  • Brain
  6 Scopus citations

• Evidence linking microRNA suppression of essential prosurvival genes with hippocampal cell death after traumatic brain injury

  Boone, D. K., Weisz, H. A., Bi, M., Falduto, M. T., Torres, K. E. O., Willey, H. E., Volsko, C. M., Kumar, A. M., Micci, M. A., Dewitt, D. S., Prough, D. S. & Hellmich, H. L., Dec 1 2017, In: Scientific reports. 7, 1, 6645.

  Research output: Contribution to journal › Article › peer-review

  • Essential Genes
  • Traumatic Brain Injury
  • MicroRNAs
  • Cell Death
  • Genes
  13 Scopus citations

• Erratum to: Evidence linking microRNA suppression of essential prosurvival genes with hippocampal cell death after traumatic brain injury (Scientific Reports, (2017), 7, 1, (6645), 10.1038/s41598-017-06341-6)

  Boone, D. K., Weisz, H. A., Bi, M., Falduto, M. T., Torres, K. E. O., Willey, H. E., Volsko, C. M., Kumar, A. M., Micci, M. A., Dewitt, D. S., Prough, D. S. & Hellmich, H. L., Dec 1 2018, In: Scientific reports. 8, 1, 14994.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Essential Genes
  • Traumatic Brain Injury
  • MicroRNAs
  • Cell Death

• Effects of Mild Blast Traumatic Brain Injury on Cerebral Vascular, Histopathological, and Behavioral Outcomes in Rats

  Rodriguez, U. A., Zeng, Y., Deyo, D., Parsley, M. A., Hawkins, B. E., Prough, D. S. & DeWitt, D. S., Jan 15 2018, In: Journal of neurotrauma. 35, 2, p. 375-392 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Brain Concussion
  • Traumatic Brain Injury
  • penicillamine methyl ester
  • Blood Vessels
  • Perfusion
  24 Scopus citations

• Effects of AAV-mediated knockdown of nNOS and GPx-1 gene expression in rat hippocampus after traumatic brain injury

  Boone, D. R., Leek, J. M., Falduto, M. T., Torres, K. E. O., Sell, S. L., Parsley, M. A., Cowart, J. C., Uchida, T., Micci, M. A., DeWitt, D. S., Prough, D. S. & Hellmich, H. L., Oct 2017, In: PloS one. 12, 10, e0185943.

  Research output: Contribution to journal › Article › peer-review

  • Dependoparvovirus
  • glutathione peroxidase GPX1
  • neuronal nitric oxide synthase
  • Nitric Oxide Synthase Type I
  • Dependovirus
  4 Scopus citations

• Development of a stretch-induced neurotrauma model for medium-throughput screening in vitro: identification of rifampicin as a neuroprotectant

  López-García, I., Gerő, D., Szczesny, B., Szoleczky, P., Olah, G., Módis, K., Zhang, K., Gao, J., Wu, P., Sowers, L. C., DeWitt, D., Prough, D. S. & Szabo, C., 2018, In: British Journal of Pharmacology. 175, 2, p. 284-300 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Rifampin
  • Neuroprotective Agents
  • Wounds and Injuries
  • In Vitro Techniques
  • Neurons
  9 Scopus citations

• Cytoprotective effect of γ-tocopherol against tumor necrosis factor α induced cell dysfunction in L929 cells

  Oláh, G., Módis, K., Gero, D., Suzuki, K., Dewit, D., Traber, D. L. & Szabó, C., Nov 2011, In: International journal of molecular medicine. 28, 5, p. 711-720 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Tocopherols
  • Tumor Necrosis Factor-alpha
  • Dactinomycin
  • Oxidants
  • Vitamins
  5 Scopus citations

• Cerebrovascular connexin expression: Effects of traumatic brain injury

  Avila, M. A., Sell, S. L., Hawkins, B. E., Hellmich, H. L., Boone, D. R., Crookshanks, J. M., Prough, D. S. & Dewitt, D. S., Sep 1 2011, In: Journal of neurotrauma. 28, 9, p. 1803-1811 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Connexins
  • Traumatic Brain Injury
  • Gap Junctions
  • Messenger RNA
  • Connexin 43
  12 Scopus citations

• Cellular bioenergetics is regulated by PARP1 under resting conditions and during oxidative stress

  Módis, K., Gerö, D., Erdélyi, K., Szoleczky, P., Dewitt, D. & Szabo, C., Mar 1 2012, In: Biochemical Pharmacology. 83, 5, p. 633-643 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxidative stress
  • Endothelial cells
  • Energy Metabolism
  • Epithelial Cells
  • Oxidative Phosphorylation
  58 Scopus citations