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Author

  • Andreas Papapetropoulos
Article

Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer

Druzhyna, N., Szczesny, B., Olah, G., Módis, K., Asimakopoulou, A., Pavlidou, A., Szoleczky, P., Gerö, D., Yanagi, K., Törö, G., López-García, I., Myrianthopoulos, V., Mikros, E., Zatarain, J. R., Chao, C., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Nov 1 2016, In : Pharmacological Research. 113, p. 18-37 20 p.

Research output: Contribution to journalArticle

25 Scopus citations

Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE)

Asimakopoulou, A., Panopoulos, P., Chasapis, C. T., Coletta, C., Zhou, Z., Cirino, G., Giannis, A., Szabo, C., Spyroulias, G. A. & Papapetropoulos, A., Jun 2013, In : British Journal of Pharmacology. 169, 4, p. 922-932 11 p.

Research output: Contribution to journalArticle

204 Scopus citations

Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation: Regulation of CSE by KLF2 and miR-27b

Bibli, S. I., Hu, J., Leisegang, M. S., Wittig, J., Zukunft, S., Kapasakalidi, A., Fisslthaler, B., Tsilimigras, D., Zografos, G., Filis, K., Brandes, R. P., Papapetropoulos, A., Sigala, F. & Fleming, I., Jan 2020, In : Redox Biology. 28, 101379.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Short-term statin administration in hypercholesterolaemic rabbits resistant to postconditioning: Effects on infarct size, endothelial nitric oxide synthase, and nitro-oxidative stress

Andreadou, I., Farmakis, D., Prokovas, E., Sigala, F., Zoga, A., Spyridaki, K., Papalois, A., Papapetropoulos, A., Anastasiou-Nana, M., Kremastinos, D. T. & Iliodromitis, E. K., Jun 1 2012, In : Cardiovascular research. 94, 3, p. 501-509 9 p.

Research output: Contribution to journalArticle

49 Scopus citations

Soluble guanylyl cyclase is a target of angiotensin II-induced nitrosative stress in a hypertensive rat model

Crassous, P. A., Couloubaly, S., Huang, C., Zhou, Z., Baskaran, P., Kim, D. D., Papapetropoulos, A., Fioramonti, X., Durán, W. N. & Beuve, A., Sep 1 2012, In : American Journal of Physiology - Heart and Circulatory Physiology. 303, 5, p. H597-H604

Research output: Contribution to journalArticle

28 Scopus citations

Synthesis and Pharmacological Evaluation of Novel Adenine-Hydrogen Sulfide Slow Release Hybrids Designed as Multitarget Cardioprotective Agents

Lougiakis, N., Papapetropoulos, A., Gikas, E., Toumpas, S., Efentakis, P., Wedmann, R., Zoga, A., Zhou, Z., Iliodromitis, E. K., Skaltsounis, A. L., Filipovic, M. R., Pouli, N., Marakos, P. & Andreadou, I., Mar 10 2016, In : Journal of Medicinal Chemistry. 59, 5, p. 1776-1790 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview

CGTP Collaborators, Dec 2017, In : British Journal of Pharmacology. 174, p. S1-S16

Research output: Contribution to journalArticle

Open Access
162 Scopus citations

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

CGTP Collaborators, Dec 1 2019, In : British Journal of Pharmacology. 176, S1, p. S297-S396

Research output: Contribution to journalArticle

Open Access
149 Scopus citations

The protective role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H2S) pathway against experimental osteoarthritis

Nasi, S., Ehirchiou, D., Chatzianastasiou, A., Nagahara, N., Papapetropoulos, A., Bertrand, J., Cirino, G., So, A. & Busso, N., Mar 17 2020, In : Arthritis Research and Therapy. 22, 1, 49.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

The role of H<inf>2</inf>S bioavailability in endothelial dysfunction

Wang, R., Szabo, C., Ichinose, F., Ahmed, A., Whiteman, M. & Papapetropoulos, A., Sep 12 2015, In : Trends in Pharmacological Sciences. 36, 9, p. 568-578 11 p.

Research output: Contribution to journalArticle

79 Scopus citations

The role of soluble Guanylyl Cyclase in chronic obstructive pulmonary disease

Glynos, C., Dupont, L. L., Vassilakopoulos, T., Papapetropoulos, A., Brouckaert, P., Giannis, A., Joos, G. F., Bracke, K. R. & Brusselle, G. G., Oct 1 2013, In : American Journal of Respiratory and Critical Care Medicine. 188, 7, p. 789-799 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Thioglycine and l-thiovaline: Biologically active H 2S-donors

Zhou, Z., Von Wantoch Rekowski, M., Coletta, C., Szabo, C., Bucci, M., Cirino, G., Topouzis, S., Papapetropoulos, A. & Giannis, A., Apr 15 2012, In : Bioorganic and Medicinal Chemistry. 20, 8, p. 2675-2678 4 p.

Research output: Contribution to journalArticle

43 Scopus citations
303 Scopus citations

Tyrosine phosphorylation of eNOS regulates myocardial survival after an ischaemic insult: Role of PYK2

Bibli, S. I., Zhou, Z., Zukunft, S., Fisslthaler, B., Andreadou, I., Szabo, C., Brouckaert, P., Fleming, I. & Papapetropoulos, A., Jul 1 2017, In : Cardiovascular research. 113, 8, p. 926-937 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Vascular biology of hydrogen sulfide

Kanagy, N. L., Szabo, C. & Papapetropoulos, A., May 2017, In : American Journal of Physiology - Cell Physiology. 312, 5, p. C537-C549

Research output: Contribution to journalArticle

66 Scopus citations
Chapter

Cooperative Interactions Between NO and H2S: Chemistry, Biology, Physiology, Pathophysiology

Kevil, C., Cortese-Krott, M. M., Nagy, P., Papapetropoulos, A., Feelisch, M. & Szabo, C., Jan 1 2017, Nitric Oxide: Biology and Pathobiology: Third Edition. Elsevier Inc., p. 57-83 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations
Comment/debate

Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” (Redox Biol. (2017) 13 (94–162)(S2213231717303373)(10.1016/j.redox.2017.05.007))

Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., Apr 2018, In : Redox Biology. 14, p. 694-696 3 p.

Research output: Contribution to journalComment/debate

Open Access
4 Scopus citations
Editorial

From primordial gas to the medicine cabinet

Papapetropoulos, A., Wallace, J. L. & Wang, R., Feb 1 2020, In : British Journal of Pharmacology. 177, 4, p. 715-719 5 p.

Research output: Contribution to journalEditorial

Open Access

Hydrogen sulfide and PKG in ischemia–reperfusion injury: sources, signaling, accelerators and brakes

Andreadou, I., Iliodromitis, E. K., Szabo, C. & Papapetropoulos, A., Sep 1 2015, In : Basic Research in Cardiology. 110, 5, 52.

Research output: Contribution to journalEditorial

12 Scopus citations

Inventing new therapies without reinventing the wheel: the power of drug repurposing

Papapetropoulos, A. & Szabo, C., 2018, In : British Journal of Pharmacology. 175, 2, p. 165-167 3 p.

Research output: Contribution to journalEditorial

18 Scopus citations

Pharmacology of the 'gasotransmitters' NO, CO and H 2 S: Translational opportunities

Papapetropoulos, A., Foresti, R. & Ferdinandy, P., Jan 1 2015, In : British Journal of Pharmacology. 172, 6, p. 1395-1396 2 p.

Research output: Contribution to journalEditorial

17 Scopus citations

Welcome note

Papapetropoulos, A., May 1 2015, In : Nitric Oxide - Biology and Chemistry. 47, S, 1 p.

Research output: Contribution to journalEditorial

Review article

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., Oct 2017, In : Redox Biology. 13, p. 94-162 69 p.

Research output: Contribution to journalReview article

Open Access
123 Scopus citations

Extending the translational potential of targeting NO/cGMP-regulated pathways in the CVS

Papapetropoulos, A., Hobbs, A. J. & Topouzis, S., Mar 2015, In : British Journal of Pharmacology. 172, 6, p. 1397-1414 18 p.

Research output: Contribution to journalReview article

Open Access
17 Scopus citations

Hydrogen sulphide and angiogenesis: Mechanisms and applications

Szabó, C. & Papapetropoulos, A., Oct 2011, In : British Journal of Pharmacology. 164, 3, p. 853-865 13 p.

Research output: Contribution to journalReview article

131 Scopus citations

Pharmacological tools for hydrogen sulphide research: A brief, introductory guide for beginners

Papapetropoulos, A., Whiteman, M. & Cirino, G., Mar 2015, In : British Journal of Pharmacology. 172, 6, p. 1633-1637 5 p.

Research output: Contribution to journalReview article

51 Scopus citations

Regulation and role of endogenously produced hydrogen sulfide in angiogenesis

Katsouda, A., Bibli, S. I., Pyriochou, A., Szabo, C. & Papapetropoulos, A., Nov 1 2016, In : Pharmacological Research. 113, p. 175-185 11 p.

Research output: Contribution to journalReview article

41 Scopus citations

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II Pathophysiological and therapeutic aspects

Módis, K., Bos, E. M., Calzia, E., Van Goor, H., Coletta, C., Papapetropoulos, A., Hellmich, M. R., Radermacher, P., Bouillaud, F. & Szabo, C., Apr 2014, In : British Journal of Pharmacology. 171, 8, p. 2123-2146 24 p.

Research output: Contribution to journalReview article

76 Scopus citations

Role of cGMP in hydrogen sulfide signaling

Bibli, S. I., Yang, G., Zhou, Z., Wang, R., Topouzis, S. & Papapetropoulos, A., Apr 30 2015, In : Nitric Oxide - Biology and Chemistry. 46, p. 7-13 7 p.

Research output: Contribution to journalReview article

27 Scopus citations

The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning

Andreadou, I., Iliodromitis, E. K., Rassaf, T., Schulz, R., Papapetropoulos, A. & Ferdinandy, P., Jan 1 2015, In : British Journal of Pharmacology. 172, 6, p. 1587-1606 20 p.

Research output: Contribution to journalReview article

116 Scopus citations