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  Expression of programmed death-ligand 1 by human colonic CD90⁺ stromal cells differs between ulcerative colitis and Crohn's disease and determines their capacity to suppress Th1 cells

  Beswick, E. J., Grim, C., Singh, A., Aguirre, J. E., Tafoya, M., Qiu, S., Rogler, G., McKee, R., Samedi, V., Ma, T. Y., Reyes, V. E., Powell, D. W. & Pinchuk, I. V., May 30 2018, In: Frontiers in immunology. 9, MAY, 1125.

  Research output: Contribution to journal › Article › peer-review

  • Th1 Cells
  • Stromal Cells
  • Ulcerative Colitis
  • Crohn Disease
  • Ligands
  18 Scopus citations

• Matrix metalloproteinases cleave membrane-bound PD-L1 on CD90⁺ (myo-)fibroblasts in Crohn’s disease and regulate T_h1/T_h17 cell responses

  Aguirre, J. E., Beswick, E. J., Grim, C., Uribe, G., Tafoya, M., Palma, G. C., Samedi, V., McKee, R., Villeger, R., Fofanov, Y., Cong, Y., Yochum, G., Koltun, W., Powell, D. & Pinchuk, I. V., Jan 1 2020, In: International immunology. 32, 1, p. 57-68 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Th17 Cells
  • Th1 Cells
  • Matrix Metalloproteinases
  • Crohn Disease
  • Fibroblasts
  4 Scopus citations