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• Article

  Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma

  Huang, Y. J., Nelson, C. E., Brodie, E. L., Desantis, T. Z., Baek, M. S., Liu, J., Woyke, T., Allgaier, M., Bristow, J., Wiener-Kronish, J. P., Sutherland, E. R., King, T. S., Icitovic, N., Martin, R. J., Calhoun, W. J., Castro, M., Denlinger, L. C., Dimango, E., Kraft, M., Peters, S. P. & 4 others, Wasserman, S. I., Wechsler, M. E., Boushey, H. A. & Lynch, S. V., Feb 2011, In: Journal of Allergy and Clinical Immunology. 127, 2, p. 372-381.e3

  Research output: Contribution to journal › Article › peer-review

  • Microbiota
  • Asthma
  • 16S Ribosomal RNA
  • Oxalobacteraceae
  • Sphingomonadaceae
  423 Scopus citations

• Aldose Reductase Inhibition Prevents Allergic Airway Remodeling through PI3K/AKT/GSK3β Pathway in Mice

  Yadav, U. C. S., Naura, A. S., Aguilera-Aguirre, L., Boldogh, I., Boulares, H. A., Calhoun, W. J., Ramana, K. V. & Srivastava, S. K., Feb 27 2013, In: PloS one. 8, 2, e57442.

  Research output: Contribution to journal › Article › peer-review

  • Aldehyde Reductase
  • phosphatidylinositol 3-kinase
  • Airway Remodeling
  • Phosphatidylinositol 3-Kinases
  • mice
  27 Scopus citations

• An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype

  Holguin, F., Comhair, S. A. A., Hazen, S. L., Powers, R. W., Khatri, S. S., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Teague, W. G., Chung, K. F., Erzurum, S. C. & Wenzel, S. E., Jan 15 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 2, p. 153-159 7 p.

  Research output: Contribution to journal › Article › peer-review

  • N,N-dimethylarginine
  • Age of Onset
  • Arginine
  • Asthma
  • Obesity
  97 Scopus citations

• Anticholinergic vs long-acting β-Agonist in combination with inhaled corticosteroids in black adults with asthma: The BELT randomized clinical trial

  Wechsler, M. E., Yawn, B. P., Fuhlbrigge, A. L., Pace, W. D., Pencina, M. J., Doros, G., Kazani, S., Raby, B. A., Lanzillotti, J., Madison, S., Israel, E., Ansari, A., Raum, D., Marthur, M., Avila, P., Bailey, J. E., Calhoun, W. J., Chang, K. L., Coto, M., Davis, C. & 8 others, Dawson, R., Ferguson, M. L. F., Dransfield, M. T., Ferguson, F., Greiner, A., Jingo, A., Pankey, W. & Schear, M., Oct 27 2015, In: JAMA - Journal of the American Medical Association. 314, 16, p. 1720-1730 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholinergic Antagonists
  • African Continental Ancestry Group
  • Tiotropium Bromide
  • Adrenal Cortex Hormones
  • Asthma
  40 Scopus citations

• Assessing and Evaluating Multidisciplinary Translational Teams: A Mixed Methods Approach

  Wooten, K. C., Rose, R. M., Ostir, G. V., Calhoun, W. J., Ameredes, B. T. & Brasier, A. R., 2014, In: Evaluation and the Health Professions. 37, 1, p. 33-49 17 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study

  Silkoff, P. E., Strambu, I., Laviolette, M., Singh, D., FitzGerald, J. M., Lam, S., Kelsen, S., Eich, A., Ludwig-Sengpiel, A., hupp, G. C., Backer, V., Porsbjerg, C., Girodet, P. O., Berger, P., Leigh, R., Kline, J. N., Dransfield, M., Calhoun, W., Hussaini, A., Khatri, S. & 8 others, Chanez, P., Susulic, V. S., Barnathan, E. S., Curran, M., Das, A. M., Brodmerkel, C., Baribaud, F. & Loza, M. J., Nov 17 2015, In: Respiratory Research. 16, 1, 142.

  Research output: Contribution to journal › Article › peer-review

  • Longitudinal Studies
  • Asthma
  • Biomarkers
  • Sputum
  • Bronchoscopy
  34 Scopus citations

• Asthma exacerbations and lung function in patients with severe or difficult-to-treat asthma

  Calhoun, W., Haselkorn, T., Miller, D. P. & Omachi, T. A., Oct 1 2015, In: Journal of Allergy and Clinical Immunology. 136, 4, p. 1125-1127e4

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Asthma is more severe in older adults

  Zein, J. G., Dweik, R. A., Comhair, S. A., Bleecker, E. R., Moore, W. C., Peters, S. P., Busse, W. W., Jarjour, N. N., Calhoun, W. J., Castro, M., Chung, K. F., Fitzpatrick, A., Israel, E., Teague, W. G., Wenzel, S. E., Love, T. E., Gaston, B. M. & Erzurum, S. C., Jul 22 2015, In: PloS one. 10, 7, e0133490.

  Research output: Contribution to journal › Article › peer-review

  • asthma
  • Asthma
  • Aging of materials
  • duration
  • Logistics
  43 Scopus citations

• Characteristics of perimenstrual asthma and its relation to asthma severity and control: Data from the Severe Asthma Research Program

  Rao, C. K., Moore, C. G., Bleecker, E., Busse, W. W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S. C., Israel, E., Curran-Everett, D. & Wenzel, S. E., Apr 2013, In: Chest. 143, 4, p. 984-992 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Aspirin
  • National Heart, Lung, and Blood Institute (U.S.)
  • Demography
  • Patient Acceptance of Health Care
  51 Scopus citations

• Children and Adults With Frequent Hospitalizations for Asthma Exacerbation, 2012-2013: A Multicenter Observational Study

  Multicenter Airway Research Collaboration-37 Investigators, Sep 1 2015, In: Journal of Allergy and Clinical Immunology: In Practice. 3, 5, p. 751-758.e1

  Research output: Contribution to journal › Article › peer-review

  • Multicenter Studies
  • Observational Studies
  • Asthma
  • Hospitalization
  • Child
  25 Scopus citations

• Chronic Respiratory Disease and Cognitive Impairment in Older Mexican Adults

  Veeranki, S., Downer, B., Jupiter, D., Kuo, Y. F., Raji, M., Calhoun, W. & Wong, R., Nov 1 2019, In: Neurology India. 67, 6, p. 1539-1542 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Cognitive Dysfunction
  • Chronic Disease
  • Logistic Models
  • Outcome Assessment (Health Care)
  • Odds Ratio

• Clinical burden and predictors of asthma exacerbations in patients on guideline-based steps 4-6 asthma therapy in the TENOR cohort

  Calhoun, W. J., Haselkorn, T., Mink, D. R., Miller, D. P., Dorenbaum, A. & Zeiger, R. S., Mar 2014, In: Journal of Allergy and Clinical Immunology: In Practice. 2, 2, p. 193-200.e3

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Guidelines
  • Odds Ratio
  • Quality of Life
  • Therapeutics
  30 Scopus citations

• Clinical implications of having reduced mid forced expiratory flow rates (FEF_25-75), independently of FEV1, in adult patients with asthma

  Riley, C. M., Wenzel, S. E., Castro, M., Erzurum, S. C., Chung, K. F., Fitzpatrick, A. M., Gaston, B., Israel, E., Moore, W. C., Bleecker, E. R., Calhoun, W. J., Jarjour, N. N., Busse, W. W., Peters, S. P., Teague, W. G., Sorkness, R. & Holguin, F., Dec 2015, In: PloS one. 10, 12, e0145476.

  Research output: Contribution to journal › Article › peer-review

  • Forced Expiratory Flow Rates
  • Intensive care units
  • Biomarkers
  • asthma
  • Eosinophils
  18 Scopus citations

• Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: The BASALT randomized controlled trial

  Calhoun, W. J., Ameredes, B. T., King, T. S., Icitovic, N., Bleecker, E. R., Castro, M., Cherniack, R. M., Chinchilli, V. M., Craig, T., Denlinger, L., DiMango, E. A., Engle, L. L., Fahy, J. V., Grant, J. A., Israel, E., Jarjour, N., Kazani, S. D., Kraft, M., Kunselman, S. J., Lazarus, S. C. & 15 others, Lemanske, R. F., Lugogo, N., Martin, R. J., Meyers, D. A., Moore, W. C., Pascual, R., Peters, S. P., Ramsdell, J., Sorkness, C. A., Sutherland, E. R., Szefler, S. J., Wasserman, S. I., Walter, M. J., Wechsler, M. E. & Boushey, H. A., Sep 5 2012, In: JAMA - Journal of the American Medical Association. 308, 10, p. 987-997 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Adrenal Cortex Hormones
  • Asthma
  • Randomized Controlled Trials
  • Biomarkers
  • Physicians
  124 Scopus citations

• Cytokine-induced glucocorticoid resistance from eosinophil activation: Protein phosphatase 5 modulation of glucocorticoid receptor phosphorylation and signaling

  Pazdrak, K., Straub, C., Maroto, R., Stafford, S., White, W. I., Calhoun, W. J. & Kurosky, A., Nov 15 2016, In: Journal of Immunology. 197, 10, p. 3782-3791 10 p.

  Research output: Contribution to journal › Article › peer-review

  • protein phosphatase 5
  • Glucocorticoid Receptors
  • Eosinophils
  • Phosphorylation
  • Cytokines
  20 Scopus citations

• Determinants of exhaled breath condensate pH in a large population with asthma

  Liu, L., Teague, W. G., Erzurum, S., Fitzpatrick, A., Mantri, S., Dweik, R. A., Bleecker, E. R., Meyers, D., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hunt, J. F. & Gaston, B., Feb 1 2011, In: Chest. 139, 2, p. 328-336 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Population
  • Dimercaprol
  • Population Dynamics
  • Gastroesophageal Reflux
  53 Scopus citations

• Detrimental effects of environmental tobacco smoke in relation to asthma severity

  Comhair, S. A. A., Gaston, B. M., Ricci, K. S., Hammel, J., Dweik, R. A., Teague, W. G., Meyers, D., Ampleford, E. J., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hazen, S. L. & 1 others, Erzurum, S. C., 2011, In: PloS one. 6, 5, e18574.

  Research output: Contribution to journal › Article › peer-review

  • Tobacco
  • asthma
  • smoke
  • Smoke
  • tobacco
  81 Scopus citations

• Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: A randomized clinical trial

  Smith, L. J., Kalhan, R., Wise, R. A., Sugar, E. A., Lima, J. J., Irvin, C. G., Dozor, A. J., Holbrook, J. T., Hanania, N., Sockrider, M., Bertrand, L., Atik, M. A., Lopez, B. A., Reibman, J., DiMango, E., Rogers, L., Carapetyan, K., Rivera, K., Bryce-Robinson, N., Scheuerman, M. & 180 others, Fiorino, E., Sundy, J., Green, D., Shah, A., Foss, C., Ghidorzi, J., Allen, S., Mervin-Blake, S., Pangborn, E., Robertson, V. S., Eberlein, N., Land, M., Vickery, B., Wu, E., Jaggers, D., Moy, J., Naureckas, E., Nevin, M., Hixon, J., Brees, A., Gonsalves, Z., Zagaja, V., Kustwin, J., Xu, B., Matthews, T., Robinson, L., Singh, N., Busk, M., Puntenney, P., Busk, N., Hutchins, J., Happel, K. I., Tejedor, R. S., Sandi, M. C., Romaine, C., Burzynski, C. J., Antoine, A., Cruse, J., Katial, R., Hoyte, F., Searing, D., Larson, T., Phillips, N., Currier, H., Blake, K., Lang, J., Mougey, E., Archer, N., Seymour, D., Warde, M., Cohen, R., Santiago, M., Ramdeo, R., Dreyfus, M., Dixon, A. E., Kaminsky, D. A., Lahiri, T., Burns, S. M., Mastronarde, J., Parsons, J., Drake, J., Santiago, J., Cosmar, D., Compton, R. A., Krishnan, S., Boyer, J., Banquet, A., De La Riva-Velasco, E., Lowenthal, D., Gjonaj, S., Kim, Y. C., Traeger, N., Welter, J., Scharbach, M., Siegel, S., Gherson, I., Monchil, L., Formisano, T. M., Williams, J., Castro, M., Bacharier, L., Sumino, K., Tarsi, J. J., Patterson, B., Montgomery, T., Slavin, R. G., Chassaing, D. K., Gerald, L. B., Goodwin, J. L., Brown, M. A., Knox, K. S., Carr, T. F., Berry, C. E., Martinez, F. D., Morgan, W. J., Daines, C. L., Daines, M. O., Grad, R., Ezmigna, D., Vasquez, M. M., Wences, J. A., Lopez, S. S., Priefert, J. C., Varela, M. T., Weese, R., Chee, K., Paco, A., Wanner, A., Lockey, R., Schmid, A., Campos, M., King, M., Mendes, E. S., Rebolledo, P. D., Arana, J., Cadet, L., McCrery, R., Croker, S. M., McCullough, S., Salzman, G., Abdeljalil, A., Pyszczynski, D., Bhat, A., Haney, P., Wasserman, S., Ramsdell, J., Soler, X., Kinninger, K., Ferguson, P., Martineau, A., Ung, S., Greene, T., Teague, W. G., Wavell, K. W., Wolf, D., Thompson-Batt, D., Bailey, W. C., Anthonisen, N., Yasin, R., Amend-Libercci, D., Adler, A., Casper, A. S., Daniel, M., Hart, A., Lears, A., Leatherman, G., Nowakowski, D., Prusakowski, N., Rayapudi, S., Rea, A., Saams, J., Shade, D., Thurman, A., Wei, C., Newcomer, A., Bime, C., Brown, E., Levine, C., Roettger, S., Wu, N., Shen, W., Wang, L., Ukken, J., Lazarus, S. C., Calhoun, W. J., Cloutier, M., Kahrilas, P., McWilliams, B., Rogatko, A., Sorkness, C., Sicherer, S., Weinmann, G., Freemer, M., Smith, R., Taggart, V., Webber, L., Zheng, G., Lancet, E., Edelman, N. H. & Rappaport, S., May 26 2015, In: JAMA - Journal of the American Medical Association. 313, 20, p. 2033-2043 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Isoflavones
  • Asthma
  • Randomized Controlled Trials
  • Lung
  • Placebos
  20 Scopus citations

• Effects of acute ethanol exposure on cytokine production by primary airway smooth muscle cells

  Kaphalia, L., Kalita, M., Kaphalia, B. & Calhoun, W., Feb 1 2016, In: Toxicology and Applied Pharmacology. 292, p. 85-93 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Acetaldehyde
  • Pulmonary diseases
  • Esters
  • Cells
  • Muscle
  7 Scopus citations

• Ethanol Exposure Impairs AMPK Signaling and Phagocytosis in Human Alveolar Macrophages: Role of Ethanol Metabolism

  Kaphalia, L., Srinivasan, M. P., Kakumanu, R. D., Kaphalia, B. S. & Calhoun, W. J., 2019, In: Alcoholism: Clinical and Experimental Research. 43, 8, p. 1682-1694 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Alveolar Macrophages
  • Oxidative stress
  • Metabolism
  • AMP-Activated Protein Kinases
  • Phagocytosis
  1 Scopus citations

• Ethanol metabolism, oxidative stress, and endoplasmic reticulum stress responses in the lungs of hepatic alcohol dehydrogenase deficient deer mice after chronic ethanol feeding

  Kaphalia, L., Boroumand, N., Hyunsu, J., Kaphalia, B. S. & Calhoun, W. J., Jun 1 2014, In: Toxicology and Applied Pharmacology. 277, 2, p. 109-117 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxidative stress
  • Peromyscus
  • Alcohol Dehydrogenase
  • Metabolism
  • Endoplasmic Reticulum Stress
  18 Scopus citations

• Evolution of Multidisciplinary Translational Teams (MTTs): Insights for Accelerating Translational Innovations

  Wooten, K. C., Calhoun, W. J., Bhavnani, S., Rose, R. M., Ameredes, B. & Brasier, A. R., Oct 2015, In: Clinical and translational science. 8, 5, p. 542-552 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Process Assessment (Health Care)
  • Productivity
  • Outcome Assessment (Health Care)
  • Consensus
  • Bibliometrics
  8 Scopus citations

• Genome-wide association study identifies T_H1 pathway genes associated with lung function in asthmatic patients

  Li, X., Hawkins, G. A., Ampleford, E. J., Moore, W. C., Li, H., Hastie, A. T., Howard, T. D., Boushey, H. A., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Israel, E., Lemanske, R. F., Szefler, S. J., Wasserman, S. I., Wenzel, S. E., Peters, S. P., Meyers, D. A. & Bleecker, E. R., Aug 2013, In: Journal of Allergy and Clinical Immunology. 132, 2, p. 313-320.e15

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Asthma
  • Lung
  • Genes
  • Single Nucleotide Polymorphism
  67 Scopus citations

• How cytokines co-occur across asthma patients: From bipartite network analysis to a molecular-based classification

  Bhavnani, S. K., Victor, S., Calhoun, W. J., Busse, W. W., Bleecker, E., Castro, M., Ju, H., Pillai, R., Oezguen, N., Bellala, G. & Brasier, A. R., Dec 2011, In: Journal of Biomedical Informatics. 44, SUPPL. 1, p. S24-S30

  Research output: Contribution to journal › Article › peer-review

  • Cytokines
  • Electric network analysis
  • Asthma
  • Glucocorticoids
  • Visualization
  21 Scopus citations

• Impact of Age and Sex on Outcomes and Hospital Cost of Acute Asthma in the United States, 2011-2012

  Zein, J. G., Udeh, B. L., Teague, W. G., Koroukian, S. M., Schlitz, N. K., Bleecker, E. R., Busse, W. B., Calhoun, W. J., Castro, M., Comhair, S. A., Fitzpatrick, A. M., Israel, E., Wenzel, S. E., Holguin, F., Gaston, B. M. & Erzurum, S. C., Jun 2016, In: PloS one. 11, 6, e0157301.

  Research output: Contribution to journal › Article › peer-review

  • Hospital Costs
  • asthma
  • Asthma
  • gender
  • Costs
  30 Scopus citations

• Impact of race on asthma treatment failures in the Asthma Clinical Research Network

  Wechsler, M. E., Castro, M., Lehman, E., Chinchilli, V. M., Sutherland, E. R., Denlinger, L., Lazarus, S. C., Peters, S. P., Israel, E., Martin, R. J., Szefler, S. J., Cherniack, R., Lemanske, R. F., Sorkness, C. A., Jarjour, N., Craig, T., Kunselman, S. J., Boushey, H. A., Fahy, J. V., Kraft, M. & 9 others, Wasserman, S., Ramsdell, J., Calhoun, W. J., Ameredes, B., Walter, M., Bleecker, E., DiMango, E., Pesola, G. R. & Smith, R., Dec 1 2011, In: American Journal of Respiratory and Critical Care Medicine. 184, 11, p. 1247-1253 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Treatment Failure
  • Asthma
  • European Continental Ancestry Group
  • African Americans
  • Bronchial Hyperreactivity
  60 Scopus citations

• Importance of hedgehog interacting protein and other lung function genes in asthma

  Li, X., Howard, T. D., Moore, W. C., Ampleford, E. J., Li, H., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Teague, W. G., Wenzel, S. E., Peters, S. P., Hawkins, G. A., Bleecker, E. R. & Meyers, D. A., Jun 2011, In: Journal of Allergy and Clinical Immunology. 127, 6, p. 1457-1465 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Hedgehog Proteins
  • Asthma
  • Lung
  • Genes
  • Single Nucleotide Polymorphism
  92 Scopus citations

• Improving Quality of Acute Asthma Care in US Hospitals: Changes Between 1999-2000 and 2012-2013

  Hasegawa, K., Tsugawa, Y., Clark, S., Eastin, C. D., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Ahn, J., Aurora, T., Brenner, B., Brown, M. A., Calhoun, W., Gough, J. E., Gharib, A., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S. & 11 others, Nowak, R., Pei, V., Press, V. G., Probst, B. D., Ramratnam, S. K., Tallar, M., Teuber, S. S., Trent, S. A., Villarreal, R., Watase, T. & Youngquist, S., Jul 1 2016, In: Chest. 150, 1, p. 112-122 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Guidelines
  • Length of Stay
  • Inpatients
  • Hospitalized Child
  10 Scopus citations

• Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study

  The ADEPT Investigators, 2016, In: Respiratory Research. 17, 1, p. 1-12 12 p., 43.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Biomarkers
  • Nitric Oxide
  • Phenotype
  • Bronchodilator Agents
  18 Scopus citations

• Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

  Torgerson, D. G., Ampleford, E. J., Chiu, G. Y., Gauderman, W. J., Gignoux, C. R., Graves, P. E., Himes, B. E., Levin, A. M., Mathias, R. A., Hancock, D. B., Baurley, J. W., Eng, C., Stern, D. A., Celedón, J. C., Rafaels, N., Capurso, D., Conti, D. V., Roth, L. A., Soto-Quiros, M., Togias, A. & 55 others, Li, X., Myers, R. A., Romieu, I., Berg, D. J. V. D., Hu, D., Hansel, N. N., Hernandez, R. D., Israel, E., Salam, M. T., Galanter, J., Avila, P. C., Avila, L., Rodriquez-Santana, J. R., Chapela, R., Rodriguez-Cintron, W., Diette, G. B., Adkinson, N. F., Abel, R. A., Ross, K. D., Shi, M., Faruque, M. U., Dunston, G. M., Watson, H. R., Mantese, V. J., Ezurum, S. C., Liang, L., Ruczinski, I., Ford, J. G., Huntsman, S., Chung, K. F., Vora, H., Li, X., Calhoun, W. J., Castro, M., Sienra-Monge, J. J., Del Rio-Navarro, B., Deichmann, K. A., Heinzmann, A., Wenzel, S. E., Busse, W. W., Gern, J. E., Lemanske, R. F., Beaty, T. H., Bleecker, E. R., Raby, B. A., Meyers, D. A., London, S. J., Gilliland, F. D., Burchard, E. G., Martinez, F. D., Weiss, S. T., Williams, L. K., Barnes, K. C., Ober, C. & Nicolae, D. L., Sep 2011, In: Nature Genetics. 43, 9, p. 887-892 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Asthma
  • Meta-Analysis
  • Population
  • Interleukin-33
  528 Scopus citations

• Mucosal bromodomain-containing protein 4 mediates aeroallergen-induced inflammation and remodeling

  Tian, B., Hosoki, K., Liu, Z., Yang, J., Zhao, Y., Sun, H., Zhou, J., Rytting, E., Kaphalia, L., Calhoun, W. J., Sur, S. & Brasier, A. R., Apr 2019, In: Journal of Allergy and Clinical Immunology. 143, 4, p. 1380-1394.e9

  Research output: Contribution to journal › Article › peer-review

  • Dander
  • Cats
  • Myofibroblasts
  • Inflammation
  • Airway Remodeling
  14 Scopus citations

• Obesity and asthma: An association modified by age of asthma onset

  Holguin, F., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Yonas, M., Teague, W. G. & Wenzel, S. E., Jun 2011, In: Journal of Allergy and Clinical Immunology. 127, 6, p. 1486-1493.e2

  Research output: Contribution to journal › Article › peer-review

  • Age of Onset
  • Asthma
  • Obesity
  • Body Mass Index
  • Phenotype
  217 Scopus citations

• P2X₇-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy

  Denlinger, L. C., Manthei, D. M., Seibold, M. A., Ahn, K., Bleecker, E., Boushey, H. A., Calhoun, W. J., Castro, M., Chinchili, V. M., Fahy, J. V., Hawkins, G. A., Icitovic, N., Israel, E., Jarjour, N. N., King, T., Kraft, M., Lazarus, S. C., Lehman, E., Martin, R. J., Meyers, D. A. & 8 others, Peters, S. P., Sheerar, D., Shi, L., Sutherland, E. R., Szefler, S. J., Wechsler, M. E., Sorkness, C. A. & Lemanske, R. F., Jan 1 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 1, p. 28-33 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Adrenal Cortex Hormones
  • Purinergic P2X7 Receptors
  • Therapeutics
  • Confidence Intervals
  13 Scopus citations

• Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling

  Zhao, Y., Tian, B., Sun, H., Zhang, J., Zhang, Y., Ivannikov, M., Motamedi, M., Liu, Z., Zhou, J., Kaphalia, L., Calhoun, W. J., Maroto, R. & Brasier, A. R., Aug 15 2019, In: Journal of Proteomics. 205, 103415.

  Research output: Contribution to journal › Article › peer-review

  • Airway Remodeling
  • Bronchoalveolar Lavage Fluid
  • Homeostasis
  • Pericytes
  • Blood Vessels
  10 Scopus citations

• Predictors of response to tiotropium versus salmeterol in asthmatic adults

  Peters, S. P., Bleecker, E. R., Kunselman, S. J., Icitovic, N., Moore, W. C., Pascual, R., Ameredes, B. T., Boushey, H. A., Calhoun, W. J., Castro, M., Cherniack, R. M., Craig, T., Denlinger, L. C., Engle, L. L., Dimango, E. A., Israel, E., Kraft, M., Lazarus, S. C., Lemanske, R. F., Lugogo, N. & 10 others, Martin, R. J., Meyers, D. A., Ramsdell, J., Sorkness, C. A., Sutherland, E. R., Wasserman, S. I., Walter, M. J., Wechsler, M. E., Chinchilli, V. M. & Szefler, S. J., Nov 2013, In: Journal of Allergy and Clinical Immunology. 132, 5, p. 1068-1074.e1

  Research output: Contribution to journal › Article › peer-review

  • Tiotropium Bromide
  • Salmeterol Xinafoate
  • Asthma
  • Albuterol
  • Vital Capacity
  86 Scopus citations

• Safety of investigative bronchoscopy in the Severe Asthma Research Program

  Moore, W. C., Evans, M. D., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Curran-Everett, D., Dweik, R. A., Gaston, B., Hew, M., Israel, E., Mayse, M. L., Pascual, R. M., Peters, S. P., Silveira, L., Wenzel, S. E. & Jarjour, N. N., Aug 2011, In: Journal of Allergy and Clinical Immunology. 128, 2, p. 328-336.e3

  Research output: Contribution to journal › Article › peer-review

  • Bronchoscopy
  • Asthma
  • Safety
  • Lung
  • Adrenal Cortex Hormones
  41 Scopus citations

• Sex differences in hospital length of stay in children and adults hospitalized for asthma exacerbation

  Hasegawa, K., Calhoun, W. J., Pei, Y. V., Chasm, R. M., Youngquist, S. T., Bittner, J. C. & Camargo, C. A., Dec 1 2015, In: Annals of Allergy, Asthma and Immunology. 115, 6, p. 533-535.e1

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• Sleep quality and asthma control and quality of life in non-severe and severe asthma

  Luyster, F. S., Teodorescu, M., Bleecker, E., Busse, W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S., Israel, E., Strollo, P. J. & Wenzel, S. E., Dec 2012, In: Sleep and Breathing. 16, 4, p. 1129-1137 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Quality Control
  • Sleep
  • Asthma
  • Gastroesophageal Reflux
  • Quality of Life
  54 Scopus citations

• Strategies for molecular classification of asthma using bipartite network analysis of cytokine expression

  Pillai, R. R., Divekar, R., Brasier, A., Bhavnani, S. & Calhoun, W. J., Oct 1 2012, In: Current Allergy and Asthma Reports. 12, 5, p. 388-395 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Cytokines
  • Health Care Costs
  • Signs and Symptoms
  • Data Analysis
  15 Scopus citations

• Symptom-based controller therapy: A new paradigm for asthma management

  Divekar, R., Ameredes, B. T. & Calhoun, W. J., Oct 2013, In: Current Allergy and Asthma Reports. 13, 5, p. 427-433 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Adrenal Cortex Hormones
  • Guidelines
  • Nebulizers and Vaporizers
  • Therapeutics
  1 Scopus citations

• The CTSA as an Exemplar Framework for Developing Multidisciplinary Translational Teams

  Calhoun, W. J., Wooten, K., Bhavnani, S., Anderson, K. E., Freeman, J. & Brasier, A. R., Feb 2013, In: Clinical and translational science. 6, 1, p. 60-71 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Education
  • Industry
  • Data Analysis
  • Technology
  • Therapeutics
  20 Scopus citations

• Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma

  Chu, D. K., Al-Garawi, A., Llop-Guevara, A., Pillai, R. A., Radford, K., Shen, P., Walker, T. D., Goncharova, S., Calhoun, W. J., Nair, P. & Jordana, M., Apr 12 2015, In: Allergy, Asthma and Clinical Immunology. 11, 1, 14.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-6
  • Asthma
  • Inflammation
  • Bronchitis
  • Chemokines
  38 Scopus citations

• The role of computed tomography in chronic obstructive pulmonary diseases

  Sze, T. F. C., Ditzler, M. G., Walser, E. M. & Calhoun, W. J., 2015, In: Journal of Allergy and Clinical Immunology: In Practice. 3, 4, p. 594-596 3 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Underuse of guideline-recommended long-term asthma management in children hospitalized to the intensive care unit: A multicenter observational study

  Hasegawa, K., Ahn, J., Brown, M. A., Press, V. G., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Aurora, T., Brenner, B., Calhoun, W., Gough, J. E., Gutta, R. C., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S., Nowak, R., Pei, V. & 9 others, Probst, B. D., Ramratnam, S. K., Tallar, M., Snipes, C., Teuber, S. S., Trent, S. A., Villarreal, R., Watase, T. & Youngquist, S., Jul 1 2015, In: Annals of Allergy, Asthma and Immunology. 115, 1, p. 10-16.e1

  Research output: Contribution to journal › Article › peer-review

  • Hospitalized Child
  • Multicenter Studies
  • Intensive Care Units
  • Observational Studies
  • Asthma
  21 Scopus citations

• Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data

  Wu, W., Bleecker, E., Moore, W., Busse, W. W., Castro, M., Chung, K. F., Calhoun, W. J., Erzurum, S., Gaston, B., Israel, E., Curran-Everett, D. & Wenzel, S. E., May 2014, In: Journal of Allergy and Clinical Immunology. 133, 5, p. 1280-1288 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Lung
  • Unsupervised Machine Learning
  • Cluster Analysis
  • Asthma and Nasal Polyps
  149 Scopus citations

• Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study

  For the ADEPT (Airways Disease Endotyping for Personalized Therapeutics) & U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) investigators, Dec 15 2016, In: Respiratory Research. 17, 1, 165.

  Research output: Contribution to journal › Article › peer-review

  • Cluster Analysis
  • Asthma
  • Phenotype
  • Inflammation
  • Interleukin-13
  47 Scopus citations
• Chapter

  Conclusions and future directions

  Calhoun, W. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  1 Scopus citations

• Conclusions and future directions

  Calhoun, W. J. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Heterogeneity of asthma in society

  Divekar, R. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Vitamin D
  • Asthma
  • Immunologic Factors
  • Animals
  • Obesity

• Heterogeneity of asthma in society

  Divekar, R. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Vitamin D
  • Asthma
  • Immunologic Factors
  • Animals
  • Obesity
  4 Scopus citations