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• Letter

  A single residue in the αb helix of the e protein is critical for Zika virus thermostability correspondence

  Xie, D. Y., Liu, Z. Y., Nian, Q. G., Zhu, L., Wang, N., Deng, Y. Q., Zhao, H., Ji, X., Li, X. F., Wang, X., Shi, P. Y. & Qin, C. F., Dec 1 2018, In: Emerging Microbes and Infections. 7, 1, 0006.

  Research output: Contribution to journal › Letter › peer-review
  3 Scopus citations

• Drug discovery for the developing world: Progress at the Novartis Institute for Tropical Diseases

  Jones, C. L., Yeung, B. K. S., Manjunatha, U., Shi, P-Y., Bodenreider, C. & Diagana, T. T., Jun 3 2015, In: Nature Reviews Drug Discovery. 14, 6, p. 442-444 3 p.

  Research output: Contribution to journal › Letter › peer-review
  4 Scopus citations
• Review article

  Antagonism of Type i Interferon by Severe Acute Respiratory Syndrome Coronavirus 2

  Xia, H. & Shi, P. Y., Dec 2020, In: Journal of Interferon and Cytokine Research. 40, 12, p. 543-548 6 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Interferons
  • Coronavirus Infections
  • Interferon Type I

• Anti-infectives: Can cellular screening deliver?

  Keller, T. H., Shi, P. Y. & Wang, Q. Y., Aug 1 2011, In: Current Opinion in Chemical Biology. 15, 4, p. 529-533 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Emerging Communicable Diseases
  • Drug Discovery
  • Diarylquinolines
  • Screening
  • Viruses
  22 Scopus citations

• Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential

  Xu, J., Shi, P. Y., Li, H. & Zhou, J., May 8 2020, In: ACS Infectious Diseases. 6, 5, p. 909-915 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Niclosamide
  • Coronavirus
  • Antiviral Agents
  • Middle East Respiratory Syndrome Coronavirus
  • SARS Virus
  65 Scopus citations

• Did Zika Virus Mutate to Cause Severe Outbreaks?

  Rossi, S. L., Ebel, G. D., Shan, C., Shi, P. Y. & Vasilakis, N., Oct 2018, In: Trends in Microbiology. 26, 10, p. 877-885 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus
  • Disease Outbreaks
  • Venezuelan Equine Encephalitis Viruses
  • Chikungunya virus
  • Arboviruses
  11 Scopus citations

• Difficulties and advancements in developing drugs for the treatment of dengue fever

  Noble, C. G. & Shi, P. Y., Jan 1 2013, In: Expert Opinion on Orphan Drugs. 1, 12, p. 947-949 3 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue
  • Dengue Virus
  • Antiviral Agents
  • Pharmaceutical Preparations
  • Culicidae
  1 Scopus citations

• Flavivirus RNA methylation

  Dong, H., Fink, K., Züst, R., Lim, S. P., Qin, C. F. & Shi, P. Y., 2014, In: Journal of General Virology. 95, PART 4, p. 763-778 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • Flavivirus
  • Methyltransferases
  • Methylation
  • Viral RNA
  • RNA
  66 Scopus citations

• Live attenuated vaccine: The first clinically approved dengue vaccine?

  Fink, K. & Shi, P. Y., Feb 1 2014, In: Expert review of vaccines. 13, 2, p. 185-188 4 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue Vaccines
  • Attenuated Vaccines
  • Dengue Virus
  • Vaccines
  • Culicidae
  14 Scopus citations

• Polymerases of hepatitis C viruses and flaviviruses: Structural and mechanistic insights and drug development

  Caillet-Saguy, C., Lim, S. P., Shi, P. Y., Lescar, J. & Bressanelli, S., May 2014, In: Antiviral research. 105, 1, p. 8-16 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Flavivirus
  • Flaviviridae
  • Drug Development
  • Hepacivirus
  • Polyproteins
  38 Scopus citations

• Potential Mechanisms for Enhanced Zika Epidemic and Disease

  Xia, H., Xie, X., Shan, C. & Shi, P-Y., May 11 2018, In: ACS Infectious Diseases. 4, 5, p. 656-659 4 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus Infection
  • Epidemics
  • Herd Immunity
  • Flavivirus
  • Mutation
  5 Scopus citations

• Reserve genetic approaches for the development of Zika vaccines and therapeutics

  Fontes-Garfias, C. R., Baker, C. K. & Shi, P. Y., Oct 2020, In: Current Opinion in Virology. 44, p. 7-15 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus
  • Vaccines
  • Reverse Genetics
  • Epidemics
  • Antiviral Agents
  2 Scopus citations

• Small Molecules and Antibodies for Zika Therapy

  Xie, X., Zou, J., Shan, C. & Shi, P. Y., 2017, In: Journal of Infectious Diseases. 216, p. S945-S950

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus Infection
  • Zika Virus
  • Antibodies
  • Clinical Trials
  • Pregnant Women
  15 Scopus citations

• Structural biology of dengue virus enzymes: Towards rational design of therapeutics

  Noble, C. G. & Shi, P. Y., Nov 1 2012, In: Antiviral research. 96, 2, p. 115-126 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue Virus
  • Methyltransferases
  • Dengue
  • Enzymes
  • Peptide Hydrolases
  78 Scopus citations

• Targeting dengue virus NS4B protein for drug discovery

  Xie, X., Zou, J., Wang, Q. Y. & Shi, P. Y., Jun 2015, In: Antiviral research. 118, p. 39-45 7 p., 3603.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue virus NS4B protein
  • Drug Discovery
  • Flavivirus
  • Proteins
  • Antiviral Agents
  44 Scopus citations

• Ten years of dengue drug discovery: Progress and prospects

  Lim, S. P., Wang, Q. Y., Noble, C. G., Chen, Y. L., Dong, H., Zou, B., Yokokawa, F., Nilar, S., Smith, P., Beer, D., Lescar, J. & Shi, P. Y., Oct 21 2013, In: Antiviral research. 100, 2, p. 500-519 20 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue Virus
  • Dengue
  • Drug Discovery
  • balapiravir
  • celgosivir
  239 Scopus citations

• The search for nucleoside/nucleotide analog inhibitors of dengue virus

  Chen, Y. L., Yokokawa, F. & Shi, P. Y., Aug 10 2015, In: Antiviral research. 122, p. 12-19 8 p., 3670.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue Virus
  • Nucleosides
  • Antiviral Agents
  • Nucleotides
  • Sofosbuvir
  43 Scopus citations

• Type I and Type III interferons restrict SARS-CoV-2 infection of human airway epithelial cultures

  Vanderheiden, A., Ralfs, P., Chirkova, T., Upadhyay, A. A., Zimmerman, M. G., Bedoya, S., Aoued, H., Tharp, G. M., Pellegrini, K. L., Manfredi, C., Sorscher, E., Mainou, B., Lobby, J. L., Kohlmeier, J. E., Lowen, A. C., Shi, P. Y., Menachery, V. D., Anderson, L. J., Grakoui, A., Bosinger, S. E. & 1 others, Suthar, M. S., Oct 2020, In: Journal of virology. 94, 19, e00985-20.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Severe acute respiratory syndrome coronavirus
  • interferon type III
  • Coronavirus Infections
  • Severe Acute Respiratory Syndrome
  • interferons
  12 Scopus citations

• West Nile virus drug discovery

  Lim, S. P. & Shi, P. Y., Dec 3 2013, In: Viruses. 5, 12, p. 2977-3006 30 p.

  Research output: Contribution to journal › Review article › peer-review

  • West Nile virus
  • Drug Discovery
  • Antiviral Agents
  • Antibodies
  • Flaviviridae
  27 Scopus citations

• Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network

  Aliota, M. T., Bassit, L., Bradrick, S. S., Cox, B., Garcia-Blanco, M. A., Gavegnano, C., Friedrich, T. C., Golos, T. G., Griffin, D. E., Haddow, A. D., Kallas, E. G., Kitron, U., Lecuit, M., Magnani, D. M., Marrs, C., Mercer, N., McSweegan, E., Ng, L. F. P., O'Connor, D. H., Osorio, J. E. & 11 others, Ribeiro, G. S., Ricciardi, M., Rossi, S. L., Saade, G., Schinazi, R. F., Schott-Lerner, G. O., Shan, C., Shi, P. Y., Watkins, D. I., Vasilakis, N. & Weaver, S. C., Aug 2017, In: Antiviral research. 144, p. 223-246 24 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus Infection
  • Zika Virus
  • Viruses
  • Routine Diagnostic Tests
  • Antiviral Agents
  66 Scopus citations

• Zika Virus Vaccine: Progress and Challenges

  Shan, C., Xie, X. & Shi, P. Y., Jul 11 2018, In: Cell Host and Microbe. 24, 1, p. 12-17 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus
  • Vaccines
  • Eye Abnormalities
  • Flavivirus
  • Explosive Agents
  34 Scopus citations
• Short survey

  Flavivirus NS5 prevents the InSTATement of IFN

  Shi, P. Y., Sep 10 2014, In: Cell Host and Microbe. 16, 3, p. 269-271 3 p.

  Research output: Contribution to journal › Short survey › peer-review

  • Flavivirus
  • Interferons
  • Yellow fever virus
  • Virus Diseases
  • Infection
  10 Scopus citations

• Therapeutics for Neglected Infectious Diseases: Progress and Challenge

  Shi, P. Y., Smith, P. W. & Diagana, T. T., Jan 8 2015, In: ACS Infectious Diseases. 1, 1, p. 76-78 3 p.

  Research output: Contribution to journal › Short survey › peer-review
  7 Scopus citations

• Unraveling a flavivirus enigma

  Shi, P. Y., Jan 1 2014, In: Science. 343, 6173, p. 849-850 2 p.

  Research output: Contribution to journal › Short survey › peer-review

  • Flavivirus
  • Proteins
  9 Scopus citations