Find Research Outputs

Search in all content

Filters for Publications

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • David Walker
Article
Open Access
2 Scopus citations

A cluster of cases of rocky mountain spotted fever in an area of Colombia not known to be endemic for this disease

Londoño, A. F., Arango-Ferreira, C., Acevedo-Gutiérrez, L. Y., Paternina, L. E., Montes, C., Ruiz, I., Labruna, M. B., Díaz, F. J., Walker, D. H. & Rodas, J. D., 2019, In : American Journal of Tropical Medicine and Hygiene. 101, 2, p. 336-342 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

A Hematogenously Disseminated Orientia tsutsugamsushi-Infected Murine Model of Scrub Typhus

Shelite, T. R., Saito, T. B., Mendell, N. L., Gong, B., Xu, G., Soong, L., Valbuena, G., Bouyer, D. H. & Walker, D. H., Jul 2014, In : PLoS neglected tropical diseases. 8, 7, e2966.

Research output: Contribution to journalArticle

22 Scopus citations
3 Scopus citations

An Intradermal Inoculation Mouse Model for Immunological Investigations of Acute Scrub Typhus and Persistent Infection

Soong, L., Mendell, N. L., Olano, J. P., Rockx-Brouwer, D., Xu, G., Goez-Rivillas, Y., Drom, C., Shelite, T. R., Valbuena, G., Walker, D. H. & Bouyer, D. H., Aug 1 2016, In : PLoS neglected tropical diseases. 10, 8, e0004884.

Research output: Contribution to journalArticle

14 Scopus citations

Approaches to vaccines against Orientia tsutsugamushi

Valbuena, G. & Walker, D. H., 2013, In : Frontiers in cellular and infection microbiology. 4, JAN, Article 170.

Research output: Contribution to journalArticle

A review of the global epidemiology of scrub typhus

Xu, G., Walker, D. H., Jupiter, D., Melby, P. C. & Arcari, C. M., Nov 3 2017, In : PLoS neglected tropical diseases. 11, 11, e0006062.

Research output: Contribution to journalArticle

67 Scopus citations

A single mutation (V64G) within the ring domain of Z attenuates junin virus

Hallam, S. J., Manning, J. T., Maruyama, J., Seregin, A., Huang, C., Walker, D. H., de la Torre, J. C. & Paessler, S., Sep 2020, In : PLoS neglected tropical diseases. 14, 9, p. 1-15 15 p., e0008555.

Research output: Contribution to journalArticle

Open Access

Atg5 supports Rickettsia australis infection in macrophages in vitro and in vivo

Bechelli, J., Vergara, L., Smalley, C., Buzhdygan, T. P., Bender, S., Zhang, W., Liu, Y., Popov, V. L., Wang, J., Garg, N., Hwang, S., Walker, D. H. & Fang, R., Jan 1 2019, In : Infection and immunity. 87, 1, e00651.

Research output: Contribution to journalArticle

9 Scopus citations

Burkholderia pseudomallei ΔtonB Δhcp1 live attenuated vaccine strain elicits full protective immunity against aerosolized melioidosis infection

Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Kilgore, P. B., Ross, B. N., Walker, D. H., Endsley, J. J. & Torresa, A. G., Jan 1 2019, In : mSphere. 4, 1, e00570-18.

Research output: Contribution to journalArticle

8 Scopus citations

Case-Fatality ratio and effectiveness of ribavirin therapy among hospitalized patients in china who had severe fever with thrombocytopenia syndrome

Liu, W., Lu, Q. B., Cui, N., Li, H., Wang, L. Y., Liu, K., Yang, Z. D., Wang, B. J., Wang, H. Y., Zhang, Y. Y., Zhuang, L., Hu, C. Y., Yuan, C., Fan, X. J., Wang, Z., Zhang, L., Zhang, X. A., Walker, D. H. & Cao, W. C., Nov 1 2013, In : Clinical Infectious Diseases. 57, 9, p. 1292-1299 8 p.

Research output: Contribution to journalArticle

91 Scopus citations

CD8+T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection

Xu, G., Mendell, N. L., Liang, Y., Shelite, T. R., Goez-Rivillas, Y., Soong, L., Bouyer, D. H. & Walker, D. H., Jul 19 2017, In : PLoS neglected tropical diseases. 11, 7, e0005763.

Research output: Contribution to journalArticle

13 Scopus citations

Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: Evidence of possible mediation by host tRNA-derived small noncoding RNAs

Gong, B., Lee, Y. S., Lee, I., Shelite, T. R., Kunkeaw, N., Xu, G., Lee, K., Jeon, S. H., Johnson, B. H., Chang, Q., Ha, T., Mendell, N. L., Cheng, X., Bouyer, D. H., Boor, P. J., Ksiazek, T. G. & Walker, D. H., Jun 23 2013, In : BMC Infectious Diseases. 13, 1, 285.

Research output: Contribution to journalArticle

23 Scopus citations
18 Scopus citations
15 Scopus citations
Open Access

Ehrlichia chaffeensis outer membrane protein 1-specific human antibody-mediated immunity is defined by intracellular TRIM21-dependent innate immune activation and extracellular neutralization

Velayutham, T. S., Kumar, S., Zhang, X., Kose, N., Walker, D. H., Winslow, G., Crowe, J. E. & McBride, J. W., Dec 1 2019, In : Infection and immunity. 87, 12, e00383-19.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
9 Scopus citations
Open Access
3 Scopus citations

Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses

Gong, B., Shelite, T., Mei, F. C., Ha, T., Hu, Y., Xu, G., Chang, Q., Wakamiya, M., Ksiazek, T. G., Boor, P. J., Bouyer, D. H., Popov, V. L., Chen, J., Walker, D. H. & Cheng, X., Nov 26 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 48, p. 19615-19620 6 p.

Research output: Contribution to journalArticle

46 Scopus citations

Fatal monocytic ehrlichiosis in woman, Mexico, 2013

Sosa-Gutierrez, C. G., Solorzano-Santos, F., Walker, D. H., Torres, J., Serrano, C. A. & Gordillo-Perez, G., May 2016, In : Emerging infectious diseases. 22, 5, p. 871-874 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Fever with thrombocytopenia associated with a novel bunyavirus in China

Yu, X. J., Liang, M. F., Zhang, S. Y., Liu, Y., Li, J. D., Sun, Y. L., Zhang, L., Zhang, Q. F., Popov, V. L., Li, C., Qu, J., Li, Q., Zhang, Y. P., Hai, R., Wu, W., Wang, Q., Zhan, F. X., Wang, X. J., Kan, B., Wang, S. W. & 26 others, Wan, K. L., Jing, H. Q., Lu, J. X., Yin, W. W., Zhou, H., Guan, X. H., Liu, J. F., Bi, Z. Q., Liu, G. H., Ren, J., Wang, H., Zhao, Z., Song, J. D., He, J. R., Wan, T., Zhang, J. S., Fu, X. P., Sun, L. N., Dong, X. P., Feng, Z. J., Yang, W. Z., Hong, T., Zhang, Y., Walker, D. H., Wang, Y. & Li, D. X., Apr 21 2011, In : New England Journal of Medicine. 364, 16, p. 1523-1532 10 p.

Research output: Contribution to journalArticle

727 Scopus citations

Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium

Sahni, A., Patel, J., Narra, H. P., Schroeder, C. L. C., Walker, D. H. & Sahni, S. K., Aug 2017, In : PloS one. 12, 8, e0183181.

Research output: Contribution to journalArticle

6 Scopus citations

Genotypic characterization of Orientia tsutsugamushi from patients in two geographical locations in Sri Lanka

Premaratna, R., Blanton, L. S., Samaraweera, D. N., de Silva, G. N. N., Chandrasena, N. T. G. A., Walker, D. H. & de Silva, H. J., Jan 13 2017, In : BMC Infectious Diseases. 17, 1, 67.

Research output: Contribution to journalArticle

6 Scopus citations

Immune Mediators of protective and pathogenic immune responses in patients with mild and fatal human monocytotropic ehrlichiosis

Ismail, N., Walker, D. H., Ghose, P. & Tang, Y. W., May 21 2012, In : BMC Immunology. 13, 26.

Research output: Contribution to journalArticle

11 Scopus citations

Immunization with Ehrlichia P28 outer membrane proteins confers protection in a mouse model of ehrlichiosis

Crocquet-Valdes, P. A., Thirumalapura, N. R., Ismail, N., Yu, X., Saito, T. B., Stevenson, H. L., Pietzsch, C. A., Thomas, S. & Walker, D. H., Dec 2011, In : Clinical and Vaccine Immunology. 18, 12, p. 2018-2025 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Inactivation of sam-methyltransferase is the mechanism of attenuation of a historic louse borne typhus vaccine strain

Liu, Y., Wu, B., Weinstock, G., Walker, D. H. & Yu, X. J., Nov 20 2014, In : PloS one. 9, 11, e113285.

Research output: Contribution to journalArticle

3 Scopus citations

Mechanisms of immunity to rickettsia and implications for vaccine development

Walker, D., Jan 1 2017, In : Revista Colombiana de Ciencias Pecuarias. 30, p. 262-263 2 p.

Research output: Contribution to journalArticle

Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus

Yun, N. E., Seregin, A. V., Walker, D. H., Popov, V. L., Walker, A. G., Smith, J. N., Miller, M., de la Torre, J. C., Smith, J. K., Borisevich, V., Fair, J. N., Wauquier, N., Grant, D. S., Bockarie, B., Bente, D. & Paessler, S., 2013, In : Journal of virology. 87, 19, p. 10908-10911 4 p.

Research output: Contribution to journalArticle

32 Scopus citations
36 Scopus citations

Murine models of scrub typhus associated with host control of Orientia tsutsugamushi infection

Mendell, N. L., Bouyer, D. H. & Walker, D. H., Mar 10 2017, In : PLoS neglected tropical diseases. 11, 3, e0005453.

Research output: Contribution to journalArticle

9 Scopus citations

MyD88 mediates instructive signaling in dendritic cells and protective inflammatory response during rickettsial infection

Bechelli, J., Smalley, C., Zhao, X., Judy, B., Valdes, P., Walker, D. H. & Fang, R., Apr 1 2016, In : Infection and immunity. 84, 4, p. 883-893 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Obligate intracellular bacterium Ehrlichia inhibiting mitochondrial activity

Liu, Y., Zhang, Z., Jiang, Y., Zhang, L., Popov, V. L., Zhang, J., Walker, D. H. & Yu, X. J., Mar 2011, In : Microbes and Infection. 13, 3, p. 232-238 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Omplete genome sequence of Ehrlichia muris strain AS145T, a model monocytotropic Ehrlichia strain

Thirumalapura, N. R., Qin, X., Kuriakose, J. A. & Walker, D., 2014, In : Genome Announcements. 2, 1, e01234-13.

Research output: Contribution to journalArticle

5 Scopus citations

Opossums and cat fleas: New insights in the ecology of murine typhus in Galveston, Texas

Blanton, L. S., Idowu, B. M., Tatsch, T. N., Henderson, J. M., Bouyer, D. H. & Walker, D. H., Aug 2016, In : American Journal of Tropical Medicine and Hygiene. 95, 2, p. 457-461 5 p.

Research output: Contribution to journalArticle

27 Scopus citations
7 Scopus citations

Person-to-person transmission of severe fever with thrombocytopenia syndrome virus

Liu, Y., Li, Q., Hu, W., Wu, J., Weng, Y., Mei, L., Walker, D. H., Ren, J., Wang, Y. & Yu, X. J., Feb 1 2012, In : Vector-Borne and Zoonotic Diseases. 12, 2, p. 156-160 5 p.

Research output: Contribution to journalArticle

148 Scopus citations

Quantitative Proteomics of the Endothelial Secretome Identifies RC0497 as Diagnostic of Acute Rickettsial Spotted Fever Infections

Zhao, Y., Fang, R., Zhang, J., Zhang, Y., Bechelli, J., Smalley, C., Valbuena, G. A., Walker, D. H., Oteo, J. A. & Brasier, A., Feb 2020, In : American Journal of Pathology. 190, 2, p. 306-322 17 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Quantitative study of Rickettsia massiliae in Rhipicephalus sanguineus organs

Milhano, N., Popov, V., Vilhena, M., Bouyer, D. H., de Sousa, R. & Walker, D. H., Oct 1 2014, In : Ticks and Tick-borne Diseases. 5, 6, p. 709-714 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis

Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In : Vaccine. 31, 50, p. 5960-5967 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
17 Scopus citations

Rickettsia australis activates inflammasome in human and murine macrophages

Smalley, C., Bechelli, J., Rockx-Brouwer, D., Saito, T., Azar, S. R., Ismail, N., Walker, D. H. & Fang, R., Jun 2016, In : PloS one. 11, 6, e0157231.

Research output: Contribution to journalArticle

13 Scopus citations
13 Scopus citations

Rickettsiae Within the Fleas of Feral Cats in Galveston, Texas

Blanton, L. S., Vohra, R. F., Fistein, L., Quade, B., Walker, D. H. & Bouyer, D. H., Sep 2019, In : Vector-Borne and Zoonotic Diseases. 19, 9, p. 647-651 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Simple method to differentiate among Rickettsia species

Peniche-Lara, G., Zavala-Velazquez, J., Dzul-Rosado, K., Walker, D. H. & Zavala-Castro, J., Apr 1 2013, In : Journal of Molecular Microbiology and Biotechnology. 23, 3, p. 203-208 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Spotted fever group Rickettsia in small rodents from areas of low endemicity for Brazilian spotted fever in the Eastern Region of Minas Gerais State, Brazil

Milagres, B. S., Padilha, A. F., Montandon, C. E., Freitas, R. N., Pacheco, R., Walker, D. H., Labruna, M. B., Mafra, C. L. & Galvão, M. A. M., May 2013, In : American Journal of Tropical Medicine and Hygiene. 88, 5, p. 937-939 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice

Soong, L., Wang, H., Shelite, T. R., Liang, Y., Mendell, N. L., Sun, J., Gong, B., Valbuena, G. A., Bouyer, D. H. & Walker, D. H., Sep 1 2014, In : PLoS neglected tropical diseases. 8, 9

Research output: Contribution to journalArticle

20 Scopus citations

Structure-based vaccines provide protection in a mouse model of ehrlichiosis

Thomas, S., Thirumalapura, N. R., Crocquet-Valdes, P. A., Luxon, B. A. & Walker, D. H., Nov 17 2011, In : PloS one. 6, 11, e27981.

Research output: Contribution to journalArticle

14 Scopus citations
1 Scopus citations