Search concepts
|
Selected Filters |
- 100 - 150 out of 170 results
- Export search results
Search results
-
Article
Role of microglia in the dissemination of zika virus from mother to fetal brain
Xu, P., Shan, C., Dunn, T. J., Xie, X., Xia, H., Gao, J., Labastida, J. A., Zou, J., Villarreal, P. P., Schlagal, C. R., Yu, Y., Vargas, G., Rossi, S. L., Vasilakis, N., Shi, P. Y., Weaver, S. C. & Wu, P., Jul 2020, In: PLoS neglected tropical diseases. 14, 7, p. 1-21 21 p., e0008413.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Safety and immunogenicity of two RNA-based covid-19 vaccine candidates
Walsh, E. E., Frenck, R. W., Falsey, A. R., Kitchin, N., Absalon, J., Gurtman, A., Lockhart, S., Neuzil, K., Mulligan, M. J., Bailey, R., Swanson, K. A., Li, P., Koury, K., Kalina, W., Cooper, D., Fontes-Garfias, C., Shi, P. Y., Türeci, Ö., Tompkins, K. R., Lyke, K. E. & 5 others, , Dec 17 2020, In: New England Journal of Medicine. 383, 25, p. 2439-2450 12 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Secondary Structure and Membrane Topology of the Full-Length Dengue Virus NS4B in Micelles
Li, Y., Wong, Y. L., Lee, M. Y., Li, Q., Wang, Q. Y., Lescar, J., Shi, P. Y. & Kang, C. B., Sep 19 2016, In: Angewandte Chemie - International Edition. 55, 39, p. 12068-12072 5 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Short Direct Repeats in the 3' Untranslated Region Are Involved in Subgenomic Flaviviral RNA Production
Zhang, Q. Y., Li, X. F., Niu, X., Li, N., Wang, H. J., Deng, C. L., Ye, H. Q., Huang, X. Y., Chen, Q., Xu, Y. P., Dong, H. L., Li, X. D., Zhao, H., Shi, P. Y., Yuan, Z. M., Gong, P., Fang, X., Qin, C. F. & Zhang, B., Feb 28 2020, In: Journal of virology. 94, 6Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Small molecule inhibitors that selectively block dengue virus methyltransferase
Lim, S. P., Sonntag, L. S., Noble, C., Nilar, S. H., Ng, R. H., Zou, G., Monaghan, P., Chung, K. Y., Dong, H., Liu, B., Bodenreider, C., Lee, G., Ding, M., Chan, W. L., Wang, G., Jian, Y. L., Chao, A. T., Lescar, J., Yin, Z., Vedananda, T. R. & 2 others, , Feb 25 2011, In: Journal of Biological Chemistry. 286, 8, p. 6233-6240 8 p.Research output: Contribution to journal › Article › peer-review
108 Scopus citations -
Spike mutation D614G alters SARS-CoV-2 fitness
Plante, J. A., Liu, Y., Liu, J., Xia, H., Johnson, B. A., Lokugamage, K. G., Zhang, X., Muruato, A. E., Zou, J., Fontes-Garfias, C. R., Mirchandani, D., Scharton, D., Bilello, J. P., Ku, Z., An, Z., Kalveram, B., Freiberg, A. N., Menachery, V. D., Xie, X., Plante, K. S. & 2 others, , 2020, (Accepted/In press) In: Nature.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Structure-activity relationship of uridine-based nucleoside phosphoramidate prodrugs for inhibition of dengue virus RNA-dependent RNA polymerase
Wang, G., Lim, S. P., Chen, Y. L., Hunziker, J., Rao, R., Gu, F., Seh, C. C., Ghafar, N. A., Xu, H., Chan, K., Lin, X., Saunders, O. L., Fenaux, M., Zhong, W., Shi, P-Y. & Yokokawa, F., Jan 1 2018, (Accepted/In press) In: Bioorganic and Medicinal Chemistry Letters.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides
Tichý, M., Pohl, R., Xu, H. Y., Chen, Y. L., Yokokawa, F., Shi, P. Y. & Hocek, M., Oct 15 2012, In: Bioorganic and Medicinal Chemistry. 20, 20, p. 6123-6133 11 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
Targeting the Achilles Heel of Mosquito-Borne Viruses for Antiviral Therapy
Jackman, J. A., Shi, P. Y. & Cho, N. J., Nov 1 2019, In: ACS Infectious Diseases. 5, 1, p. 4-8 5 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
The 5′ and 3′ downstream AUG region elements are required for mosquito-borne flavivirus RNA replication
Friebe, P., Shi, P. Y. & Harris, E., Feb 2011, In: Journal of virology. 85, 4, p. 1900-1905 6 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
The C-terminal helical domain of dengue virus precursor membrane protein is involved in virus assembly and entry
Hsieh, S. C., Zou, G., Tsai, W. Y., Qing, M., Chang, G. J., Shi, P. Y. & Wang, W. K., Feb 5 2011, In: Virology. 410, 1, p. 170-180 11 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
The emerging duck flavivirus is not pathogenic for primates and is highly sensitive to mammalian interferon antiviral signaling
Wang, H. J., Li, X. F., Liu, L., Xu, Y. P., Ye, Q., Deng, Y. Q., Huang, X. Y., Zhao, H., Qin, E. D., Shi, P. Y., Gao, G. F. & Qina, C. F., 2016, In: Journal of virology. 90, 14, p. 6538-6548 11 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
The helical domains of the stem region of dengue virus envelope protein are involved in both virus assembly and entry
Lin, S. R., Zou, G., Hsieh, S. C., Qing, M., Tsai, W. Y., Shi, P. Y. & Wang, W. K., May 2011, In: Journal of virology. 85, 10, p. 5159-5171 13 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
The Interface between Methyltransferase and Polymerase of NS5 Is Essential for Flavivirus Replication
Li, X. D., Shan, C., Deng, C. L., Ye, H. Q., Shi, P. Y., Yuan, Z. M., Gong, P. & Zhang, B., May 2014, In: PLoS neglected tropical diseases. 8, 5, e2891.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Therapeutics for Dengue: Recommendations for Design and Conduct of Early-Phase Clinical Trials
Simmons, C. P., Wolbers, M., Nguyen, M. N., Whitehorn, J., Shi, P. Y., Young, P., Petric, R., Nguyen, V. V. C., Farrar, J. & Wills, B., Sep 2012, In: PLoS neglected tropical diseases. 6, 9, e1752.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
The role of sequence context, nucleotide pool balance and stress in 2'-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA
Wang, J., Dong, H., Chionh, Y. H., Mcbee, M. E., Sirirungruang, S., Cunningham, R. P., Shi, P. Y. & Dedon, P. C., Oct 14 2016, In: Nucleic acids research. 44, 18, p. 8962-8975 14 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
The stem region of premembrane protein plays an important role in the virus surface protein rearrangement during dengue maturation
Zhang, Q., Hunke, C., Yau, Y. H., Seow, V., Lee, S., Tanner, L. B., Guan, X. L., Wenk, M. R., Fibriansah, G., Chew, P. L., Kukkaro, P., Biuković, G., Shi, P. Y., Shochat, S. G., Grüber, G. & Lok, S. M., Nov 23 2012, In: Journal of Biological Chemistry. 287, 48, p. 40525-40534 10 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
The structural basis for serotype-specific neutralization of dengue virus by a human antibody
Teoh, E. P., Kukkaro, P., Teo, E. W., Lim, A. P. C., Tan, T. T., Yip, A., Schul, W., Aung, M., Kostyuchenko, V. A., Leo, Y. S., Chan, S. H., Smith, K. G. C., Chan, A. H. Y., Zou, G., Ooi, E. E., Kemeny, D. M., Tan, G. K., Ng, J. K. W., Ng, M. L., Alonso, S. & 5 others, , Jun 20 2012, In: Science Translational Medicine. 4, 139, 139ra83.Research output: Contribution to journal › Article › peer-review
165 Scopus citations -
Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses
Prasanth, K. R., Hirano, M., Fagg, W. S., McAnarney, E. T., Shan, C., Xie, X., Hage, A., Pietzsch, C. A., Bukreyev, A., Rajsbaum, R., Shi, P. Y., Bedford, M. T., Bradrick, S. S., Menachery, V. & Garcia-Blanco, M. A., Oct 2020, In: Antiviral research. 182, 104874.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Transmembrane domains of NS2B contribute to both viral RNA replication and particle formation in Japanese encephalitis virus
Li, X. D., Deng, C. L., Ye, H. Q., Zhang, H. L., Zhang, Q. Y., Chen, D. D., Zhang, P. T., Shi, P. Y., Yuan, Z. M. & Zhang, B., Jun 1 2016, In: Journal of virology. 90, 12, p. 5735-5749 15 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Treatment of human glioblastoma with a live attenuated Zika virus vaccine candidate
Chen, Q., Wu, J., Ye, Q., Ma, F., Zhu, Q., Wu, Y., Shan, C., Xie, X., Li, D., Zhan, X., Li, C., Li, X. F., Qin, X., Zhao, T., Wu, H., Shi, P. Y., Man, J. & Qin, C. F., Sep 1 2018, In: mBio. 9, 5, e01683-18.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies
Arora, R., Liew, C. W., Soh, T. S., Otoo, D. A., Seh, C. C., Yue, K., Nilar, S., Wang, G., Yokokawa, F., Noble, C. G., Chen, Y. L., Shi, P. Y., Lescar, J., Smith, T. M., Benson, T. E. & Lim, S. P., Dec 2020, In: Journal of virology. 94, 24, e01130-20.Research output: Contribution to journal › Article › peer-review
-
Type I interferon signals in macrophages and dendritic cells control dengue virus infection: Implications for a new mouse model to test dengue vaccines
Züst, R., Toh, Y. X., Valdés, I., Cerny, D., Heinrich, J., Hermida, L., Marcos, E., Guillén, G., Kalinke, U., Shi, P. Y. & Fink, K., 2014, In: Journal of virology. 88, 13, p. 7276-7285 10 p.Research output: Contribution to journal › Article › peer-review
52 Scopus citations -
U18666A, an intra-cellular cholesterol transport inhibitor, inhibits dengue virus entry and replication
Poh, M. K., Shui, G., Xie, X., Shi, P. Y., Wenk, M. R. & Gu, F., Jan 2012, In: Antiviral research. 93, 1, p. 191-198 8 p.Research output: Contribution to journal › Article › peer-review
72 Scopus citations -
Use of the immunoglobulin G avidity assay to differentiate between recent Zika and past dengue virus infections
Furuya, A. K. M., Hunt, D., St. George, K., Dupuis, A. P., Kramer, L. D., Shi, P. Y. & Wong, S., Apr 15 2019, In: Clinical Science. 133, 7, p. 859-867 9 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Using a virion assembly-defective dengue virus as a vaccine approach
Shan, C., Xie, X., Zou, J., Züst, R., Zhang, B., Ambrose, R., Mackenzie, J., Fink, K. & Shi, P. Y., Nov 1 2018, In: Journal of virology. 92, 21, e01002.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Using next generation sequencing to study the genetic diversity of candidate live attenuated zika vaccines
Collins, N. D., Shan, C., Nunes, B. T. D., Widen, S. G., Shi, P. Y., Barrett, A. D. T. & Sarathy, V. V., Apr 2020, In: Vaccines. 8, 2, 161.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Using recombination-dependent lethal mutations to stabilize reporter flaviviruses for rapid serodiagnosis and drug discovery
Baker, C., Xie, X., Zou, J., Muruato, A., Fink, K. & Shi, P. Y., Jul 2020, In: EBioMedicine. 57, 102838.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Vesicular stomatitis virus and DNA vaccines expressing zika virus nonstructural protein 1 induce substantial but not sterilizing protection against zika virus infection
Li, A., Xue, M., Attia, Z., Yu, J., Lu, M., Shan, C., Liang, X., Gao, T. Z., Shi, P. Y., Peeples, M. E., Boyaka, P. N., Liu, S. L. & Li, J., Sep 2020, In: Journal of virology. 94, 17, e00048-20.Research output: Contribution to journal › Article › peer-review
-
West nile virus experimental evolution in vivo and the trade-off hypothesis
Deardorff, E. R., Fitzpatrick, K. A., Jerzak, G. V. S., Shi, P. Y., Kramer, L. D. & Ebel, G. D., Nov 2011, In: PLoS pathogens. 7, 11, e1002335.Research output: Contribution to journal › Article › peer-review
70 Scopus citations -
Zika structural genes determine the virulence of African and Asian lineages
Nunes, B. T. D., Fontes-Garfias, C. R., Shan, C., Muruato, A. E., Nunes, J. G. C., Burbano, R. M. R., Vasconcelos, P. F. C., Shi, P. Y. & Medeiros, D. B. A., Jan 1 2020, In: Emerging Microbes and Infections. 9, 1, p. 1023-1033 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Zika Virus: Diagnosis, Therapeutics, and Vaccine
Shan, C., Xie, X., Barrett, A. D. T., Garcia-Blanco, M. A., Tesh, R. B., Vasconcelos, P. F. D. C., Vasilakis, N., Weaver, S. C. & Shi, P. Y., Mar 11 2016, In: ACS Infectious Diseases. 2, 3, p. 170-172 3 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
Zika virus epidemic in Brazil. I. Fatal disease in adults: Clinical and laboratorial aspects
Azevedo, R. S. S., Araujo, M. T., Martins Filho, A. J., Oliveira, C. S., Nunes, B. T. D., Cruz, A. C. R., Nascimento, A. G. P. A. C., Medeiros, R. C., Caldas, C. A. M., Araujo, F. C., Quaresma, J. A. S., Vasconcelos, B. C. B., Queiroz, M. G. L., da Rosa, E. S. T., Henriques, D. F., Silva, E. V. P., Chiang, J. O., Martins, L. C., Medeiros, D. B. A., Lima, J. A. & 7 others, , Dec 1 2016, In: Journal of Clinical Virology. 85, p. 56-64 9 p.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Zika virus infection elicits auto-antibodies to C1q
Koma, T., Veljkovic, V., Anderson, D. E., Wang, L. F., Rossi, S. L., Shan, C., Shi, P. Y., Beasley, D. W., Bukreyeva, N., Smith, J. N., Hallam, S., Huang, C., Von Messling, V. & Paessler, S., Dec 1 2018, In: Scientific reports. 8, 1, 1882.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Zika virus NS2A-mediated virion assembly
Zhang, X., Xie, X., Xia, H., Zou, J., Huang, L., Popov, V. L., Chen, X. & Shi, P. Y., 2019, In: mBio. 10, 5, e02375-19.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease
Akiyama, B. M., Laurence, H. M., Massey, A. R., Costantino, D. A., Xie, X., Yang, Y., Shi, P. Y., Nix, J. C., Beckham, J. D. & Kieft, J. S., Dec 2 2016, In: Science. 354, 6316, p. 1148-1152 5 p.Research output: Contribution to journal › Article › peer-review
106 Scopus citations -
Zika Virus Replicons for Drug Discovery
Xie, X., Zou, J., Shan, C., Yang, Y., Kum, D. B., Dallmeier, K., Neyts, J. & Shi, P. Y., Oct 1 2016, In: EBioMedicine. 12, p. 156-160 5 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
Chapter
Dengue drug discovery
Shi, P. Y., Yin, Z., Nilar, S. & Keller, T. H., Oct 31 2011, Third World Diseases. Elliot, R. (ed.). p. 243-276 34 p. (Topics in Medicinal Chemistry; vol. 7).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Detection and quantification of flavivirus NS5 methyl-transferase activities
Lim, S. P., Bodenreider, C. & Shi, P. Y., Jul 18 2013, Antiviral Methods and Protocols. p. 249-268 20 p. (Methods in Molecular Biology; vol. 1030).Research output: Chapter in Book/Report/Conference proceeding › Chapter
5 Scopus citations -
Discovery of potent non-nucleoside inhibitors of dengue viral RNA-dependent rna polymerase from fragment screening and structure-guided design
Lim, S. P., Noble, C. G., Nilar, S., Shi, P. Y. & Yokokawa, F., 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 187-198 12 p. (Advances in Experimental Medicine and Biology; vol. 1062).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Testing Antiviral Compounds in a Dengue Mouse Model
Schul, W., Yip, A. & Shi, P. Y., Jul 18 2013, Antiviral Methods and Protocols. p. 269-281 13 p. (Methods in Molecular Biology; vol. 1030).Research output: Chapter in Book/Report/Conference proceeding › Chapter
3 Scopus citations -
Comment/debate
Corrigendum to "Population variation of West Nile virus confers a host-specific fitness benefit in mosquitoes" [Virology 404 (2010) 89-95]
Fitzpatrick, K. A., Deardorff, E. R., Pesko, K., Brackney, D. E., Zhang, B., Bedrick, E., Shi, P. Y. & Ebel, G. D., Feb 20 2011, In: Virology. 410, 2, p. 437 1 p.Research output: Contribution to journal › Comment/debate › peer-review
-
Erratum: Treatment of human glioblastoma with a live attenuated zika virus vaccine candidate (mBio, (2018) 9(5), e01683-18, 10.1128/mBio.01683-18)
Chen, Q., Wu, J., Ye, Q., Ma, F., Zhu, Q., Wu, Y., Shan, C., Xie, X., Li, D., Zhan, X., Li, C., Li, X. F., Qin, X., Zhao, T., Wu, H., Shi, P. Y., Man, J. & Qin, C. F., Mar 1 2019, In: mBio. 10, 2, e00433-19.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Erratum to: Targeting vesicle size (Nature Materials, (2018), 17, 11, (955-956), 10.1038/s41563-018-0200-8)
Fei, Z. & Shi, P. Y., Dec 1 2018, In: Nature Materials. 17, 12, p. 1164 1 p.Research output: Contribution to journal › Comment/debate › peer-review
-
Targeting vesicle size
Zou, J. & Shi, P. Y., Nov 1 2018, In: Nature Materials. 17, 11, p. 955-956 2 p.Research output: Contribution to journal › Comment/debate › peer-review
-
Zika virus: a new threat from mosquitoes
Li, X. F., Han, J. F., Shi, P. Y. & Qin, C. F., Apr 1 2016, In: Science China. Life sciences. 59, 4, p. 440-442 3 p.Research output: Contribution to journal › Comment/debate › peer-review
13 Scopus citations -
Editorial
Report of the fifth symposium on emerging viral diseases
Zhang, B. & Shi, P. Y., Apr 2013, In: Virologica Sinica. 28, 2, p. 63-64 2 p.Research output: Contribution to journal › Editorial › peer-review
-
Letter
A single residue in the αb helix of the e protein is critical for Zika virus thermostability correspondence
Xie, D. Y., Liu, Z. Y., Nian, Q. G., Zhu, L., Wang, N., Deng, Y. Q., Zhao, H., Ji, X., Li, X. F., Wang, X., Shi, P. Y. & Qin, C. F., Dec 1 2018, In: Emerging Microbes and Infections. 7, 1, 0006.Research output: Contribution to journal › Letter › peer-review
3 Scopus citations -
Review article
Antagonism of Type i Interferon by Severe Acute Respiratory Syndrome Coronavirus 2
Xia, H. & Shi, P. Y., Dec 2020, In: Journal of Interferon and Cytokine Research. 40, 12, p. 543-548 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Anti-infectives: Can cellular screening deliver?
Keller, T. H., Shi, P. Y. & Wang, Q. Y., Aug 1 2011, In: Current Opinion in Chemical Biology. 15, 4, p. 529-533 5 p.Research output: Contribution to journal › Review article › peer-review
22 Scopus citations