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Article
A Hematogenously Disseminated Orientia tsutsugamsushi-Infected Murine Model of Scrub Typhus
Shelite, T. R., Saito, T. B., Mendell, N. L., Gong, B., Xu, G., Soong, L., Valbuena, G., Bouyer, D. H. & Walker, D. H., Jul 2014, In: PLoS neglected tropical diseases. 8, 7, e2966.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Analysis of health-Care charges in murine typhus: Need for improved clinical recognition and diagnostics for acute disease
Vohra, R. F., Walker, D. H. & Blanton, L. S., 2018, In: American Journal of Tropical Medicine and Hygiene. 98, 6, p. 1594-1598 5 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Approaches to vaccines against Orientia tsutsugamushi
Valbuena, G. & Walker, D. H., 2013, In: Frontiers in cellular and infection microbiology. 4, JAN, Article 170.Research output: Contribution to journal › Article › peer-review
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A review of the global epidemiology of scrub typhus
Xu, G., Walker, D. H., Jupiter, D., Melby, P. C. & Arcari, C. M., Nov 3 2017, In: PLoS neglected tropical diseases. 11, 11, e0006062.Research output: Contribution to journal › Article › peer-review
75 Scopus citations -
Case-Fatality ratio and effectiveness of ribavirin therapy among hospitalized patients in china who had severe fever with thrombocytopenia syndrome
Liu, W., Lu, Q. B., Cui, N., Li, H., Wang, L. Y., Liu, K., Yang, Z. D., Wang, B. J., Wang, H. Y., Zhang, Y. Y., Zhuang, L., Hu, C. Y., Yuan, C., Fan, X. J., Wang, Z., Zhang, L., Zhang, X. A., Walker, D. H. & Cao, W. C., Nov 1 2013, In: Clinical Infectious Diseases. 57, 9, p. 1292-1299 8 p.Research output: Contribution to journal › Article › peer-review
100 Scopus citations -
CD8+T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection
Xu, G., Mendell, N. L., Liang, Y., Shelite, T. R., Goez-Rivillas, Y., Soong, L., Bouyer, D. H. & Walker, D. H., Jul 19 2017, In: PLoS neglected tropical diseases. 11, 7, e0005763.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: Evidence of possible mediation by host tRNA-derived small noncoding RNAs
Gong, B., Lee, Y. S., Lee, I., Shelite, T. R., Kunkeaw, N., Xu, G., Lee, K., Jeon, S. H., Johnson, B. H., Chang, Q., Ha, T., Mendell, N. L., Cheng, X., Bouyer, D. H., Boor, P. J., Ksiazek, T. G. & Walker, D. H., Jun 23 2013, In: BMC Infectious Diseases. 13, 1, 285.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium
Fang, R., Ismail, N. & Walker, D. H., Jul 2012, In: American Journal of Pathology. 181, 1, p. 185-195 11 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Diagnosing emerging and reemerging infectious diseases: The pivotal role of the pathologist
Olano, J. P. & Walker, D. H., Jan 1 2011, In: Archives of Pathology and Laboratory Medicine. 135, 1, p. 83-91 9 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses
Gong, B., Shelite, T., Mei, F. C., Ha, T., Hu, Y., Xu, G., Chang, Q., Wakamiya, M., Ksiazek, T. G., Boor, P. J., Bouyer, D. H., Popov, V. L., Chen, J., Walker, D. H. & Cheng, X., Nov 26 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 48, p. 19615-19620 6 p.Research output: Contribution to journal › Article › peer-review
49 Scopus citations -
Fever with thrombocytopenia associated with a novel bunyavirus in China
Yu, X. J., Liang, M. F., Zhang, S. Y., Liu, Y., Li, J. D., Sun, Y. L., Zhang, L., Zhang, Q. F., Popov, V. L., Li, C., Qu, J., Li, Q., Zhang, Y. P., Hai, R., Wu, W., Wang, Q., Zhan, F. X., Wang, X. J., Kan, B., Wang, S. W. & 26 others, , Apr 21 2011, In: New England Journal of Medicine. 364, 16, p. 1523-1532 10 p.Research output: Contribution to journal › Article › peer-review
767 Scopus citations -
Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium
Sahni, A., Patel, J., Narra, H. P., Schroeder, C. L. C., Walker, D. H. & Sahni, S. K., Aug 2017, In: PloS one. 12, 8, e0183181.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Genotypic characterization of Orientia tsutsugamushi from patients in two geographical locations in Sri Lanka
Premaratna, R., Blanton, L. S., Samaraweera, D. N., de Silva, G. N. N., Chandrasena, N. T. G. A., Walker, D. H. & de Silva, H. J., Jan 13 2017, In: BMC Infectious Diseases. 17, 1, 67.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Immune Mediators of protective and pathogenic immune responses in patients with mild and fatal human monocytotropic ehrlichiosis
Ismail, N., Walker, D. H., Ghose, P. & Tang, Y. W., May 21 2012, In: BMC Immunology. 13, 26.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Immunization with Ehrlichia P28 outer membrane proteins confers protection in a mouse model of ehrlichiosis
Crocquet-Valdes, P. A., Thirumalapura, N. R., Ismail, N., Yu, X., Saito, T. B., Stevenson, H. L., Pietzsch, C. A., Thomas, S. & Walker, D. H., Dec 2011, In: Clinical and Vaccine Immunology. 18, 12, p. 2018-2025 8 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Inactivation of sam-methyltransferase is the mechanism of attenuation of a historic louse borne typhus vaccine strain
Liu, Y., Wu, B., Weinstock, G., Walker, D. H. & Yu, X. J., Nov 20 2014, In: PloS one. 9, 11, e113285.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Mechanisms of immunity to rickettsia and implications for vaccine development
Walker, D., Jan 1 2017, In: Revista Colombiana de Ciencias Pecuarias. 30, p. 262-263 2 p.Research output: Contribution to journal › Article › peer-review
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Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus
Yun, N. E., Seregin, A. V., Walker, D. H., Popov, V. L., Walker, A. G., Smith, J. N., Miller, M., de la Torre, J. C., Smith, J. K., Borisevich, V., Fair, J. N., Wauquier, N., Grant, D. S., Bockarie, B., Bente, D. & Paessler, S., 2013, In: Journal of virology. 87, 19, p. 10908-10911 4 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
Molecular and cellular pathobiology of Ehrlichia infection: Targets for new therapeutics and immunomodulation strategies
McBride, J. W. & Walker, D. H., Jan 2011, In: Expert reviews in molecular medicine. 13, e3.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
Murine models of scrub typhus associated with host control of Orientia tsutsugamushi infection
Mendell, N. L., Bouyer, D. H. & Walker, D. H., Mar 10 2017, In: PLoS neglected tropical diseases. 11, 3, e0005453.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Obligate intracellular bacterium Ehrlichia inhibiting mitochondrial activity
Liu, Y., Zhang, Z., Jiang, Y., Zhang, L., Popov, V. L., Zhang, J., Walker, D. H. & Yu, X. J., Mar 2011, In: Microbes and Infection. 13, 3, p. 232-238 7 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Omplete genome sequence of Ehrlichia muris strain AS145T, a model monocytotropic Ehrlichia strain
Thirumalapura, N. R., Qin, X., Kuriakose, J. A. & Walker, D., 2014, In: Genome Announcements. 2, 1, e01234-13.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Person-to-person transmission of severe fever with thrombocytopenia syndrome virus
Liu, Y., Li, Q., Hu, W., Wu, J., Weng, Y., Mei, L., Walker, D. H., Ren, J., Wang, Y. & Yu, X. J., Feb 1 2012, In: Vector-Borne and Zoonotic Diseases. 12, 2, p. 156-160 5 p.Research output: Contribution to journal › Article › peer-review
157 Scopus citations -
Quantitative study of Rickettsia massiliae in Rhipicephalus sanguineus organs
Milhano, N., Popov, V., Vilhena, M., Bouyer, D. H., de Sousa, R. & Walker, D. H., Oct 1 2014, In: Ticks and Tick-borne Diseases. 5, 6, p. 709-714 6 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis
Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In: Vaccine. 31, 50, p. 5960-5967 8 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
"rickettsia amblyommii" Induces cross protection against lethal rocky mountain spotted fever in a guinea pig model
Blanton, L. S., Mendell, N. L., Walker, D. H. & Bouyer, D. H., Aug 1 2014, In: Vector-Borne and Zoonotic Diseases. 14, 8, p. 557-562 6 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Rickettsiae and ehrlichiae within a city park: Is the urban dweller at risk?
Blanton, L. S., Walker, D. H. & Bouyer, D. H., Feb 1 2014, In: Vector-Borne and Zoonotic Diseases. 14, 2, p. 168-170 3 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Simple method to differentiate among Rickettsia species
Peniche-Lara, G., Zavala-Velazquez, J., Dzul-Rosado, K., Walker, D. H. & Zavala-Castro, J., Apr 2013, In: Journal of Molecular Microbiology and Biotechnology. 23, 3, p. 203-208 6 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Spotted fever group Rickettsia in small rodents from areas of low endemicity for Brazilian spotted fever in the Eastern Region of Minas Gerais State, Brazil
Milagres, B. S., Padilha, A. F., Montandon, C. E., Freitas, R. N., Pacheco, R., Walker, D. H., Labruna, M. B., Mafra, C. L. & Galvão, M. A. M., May 2013, In: American Journal of Tropical Medicine and Hygiene. 88, 5, p. 937-939 3 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice
Soong, L., Wang, H., Shelite, T. R., Liang, Y., Mendell, N. L., Sun, J., Gong, B., Valbuena, G. A., Bouyer, D. H. & Walker, D. H., Sep 1 2014, In: PLoS neglected tropical diseases. 8, 9Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Structure-based vaccines provide protection in a mouse model of ehrlichiosis
Thomas, S., Thirumalapura, N. R., Crocquet-Valdes, P. A., Luxon, B. A. & Walker, D. H., Nov 17 2011, In: PloS one. 6, 11, e27981.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Systemic treatment with cpg-b after sublethal rickettsial infection induces mouse death through indoleamine 2,3-dioxygenase (ido)
Xin, L., Shelite, T. R., Gong, B., Mendell, N. L., Soong, L., Fang, R. & Walker, D. H., Mar 28 2012, In: PloS one. 7, 3, e34062.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
The pathogenesis of severe fever with thrombocytopenia syndrome virus infection in alpha/beta interferon knockout mice: Insights into the pathologic mechanisms of a new viral hemorrhagic fever
Liu, Y., Wu, B., Paessler, S., Walker, D. H., Tesh, R. B. & Yu, X. J., Feb 2014, In: Journal of virology. 88, 3, p. 1781-1786 6 p.Research output: Contribution to journal › Article › peer-review
70 Scopus citations -
Time to Worry about Anthrax Again
Keim, P. S., Walker, D. H. & Zilinskas, R. A., Mar 14 2017, In: Scientific American. 316, 4, p. 70-75 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Book
Tropical Infectious Diseases
Guerrant, R., Walker, D. H. & Weller, P., 2011, Elsevier Inc.Research output: Book/Report › Book
24 Scopus citations -
Chapter
Anthrax
Rao, G. R. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 261-264 4 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Bartonelloses
Dehio, C., Maguiña, C. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 265-270 6 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Chlamydial, Mycoplasmal, Rickettsial, and Ehrlichial Diseases
Walker, D. H., 2018, Pulmonary Pathology: A Volume in the Series: Foundations in Diagnostic Pathology. Elsevier Inc., p. 315-326 12 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Diseases Caused by Fungi
Walker, D. H. & McGinnis, M. R., Jan 1 2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 217-221 5 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Distinguishing Tropical Infectious Diseases from Bioterrorism
Olano, J. P., Peters, C. J. & Walker, D. H., 2011, Tropical Infectious Diseases. Elsevier Inc., p. 879-886 8 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Ehrlichia
Thirumalapura, N. R. & Walker, D., Nov 26 2014, Molecular Medical Microbiology: Second Edition. Elsevier Ltd, Vol. 3. p. 2011-2032 22 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Ehrlichia chaffeensis (Human Monocytotropic Ehrlichiosis), Anaplasma phagocytophilum (Human Granulocytotropic Anaplasmosis), and Other Anaplasmataceae
Dumler, J. S. & Walker, D. H., Aug 28 2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 2. p. 2227-2233.e3Research output: Chapter in Book/Report/Conference proceeding › Chapter
9 Scopus citations -
Human ehrlichioses and rickettsioses in Cameroon
Ndip, LN., Ndip, R., Walker, D. H. & McBride, J. W., 2012, Current Topics in Tropical Medicine. p. 25-42Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Immunohistology of Infectious Diseases
Ezyaguirre, E. J., Walker, D. H. & Zaki, S., 2011, Diagnostic Immunohistochemistry. Elsevier Inc., p. 58-82 25 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Interactions of Pathogens with the Host
Walker, D., Jan 1 2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 214-216 3 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Pathogenesis of Infectious Diseases and Mechanisms of Immunity
McBride, J. & Walker, D., Dec 9 2014, Vaccinology: An Essential Guide. Wiley Blackwell, p. 59-72 14 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Principles of Diagnosis of Infectious Diseases
Walker, D., Jan 1 2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 222-225 4 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Principles of Parasitism: Host-Parasite Interactions
Olano, J. P., Weller, P. F., Guerrant, R. L. & Walker, D. H., 2011, Tropical Infectious Diseases. Elsevier Inc., p. 1-7 7 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Rickettsia, orientia, ehrlichia, anaplasma and coxiella: Typhus; spotted fevers; scrub typhus; ehrlichioses; Q fever
Walker, D. & Yu, X. J., Jul 23 2012, Medical Microbiology: Eighteenth Edition. Elsevier Inc., p. 390-399 10 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Rickettsia prowazekii (Epidemic or Louse-Borne Typhus)
Blanton, L. S. & Walker, D. H., Aug 28 2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 2. p. 2217-2220.e1Research output: Chapter in Book/Report/Conference proceeding › Chapter