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  2′-O methylation of internal adenosine by flavivirus NS5 methyltransferase

  Dong, H., Chang, D. C., Hua, M. H. C., Lim, S. P., Chionh, Y. H., Hia, F., Lee, Y. H., Kukkaro, P., Lok, S. M., Dedon, P. C. & Shi, P. Y., Apr 2012, In: PLoS pathogens. 8, 4, e1002642.

  Research output: Contribution to journal › Article › peer-review

  • Flavivirus
  • Methyltransferases
  • Adenosine
  • Methylation
  • 2'-O-methyladenosine
  84 Scopus citations

• A cDNA Clone-Launched Platform for High-Yield Production of Inactivated Zika Vaccine

  Yang, Y., Shan, C., Zou, J., Muruato, A. E., Bruno, D. N., de Almeida Medeiros Daniele, B., Vasconcelos, P. F. C., Rossi, S. L., Weaver, S. C., Xie, X. & Shi, P. Y., Mar 1 2017, In: EBioMedicine. 17, p. 145-156 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Inactivated Vaccines
  • Viruses
  • Zika Virus
  • Complementary DNA
  • Clone Cells
  27 Scopus citations

• A chimeric dengue virus vaccine using japanese encephalitis virus vaccine strain SA14-14-2 as backbone is immunogenic and protective against either parental virus in mice and nonhuman primates

  Li, X. F., Deng, Y. Q., Yang, H. Q., Zhao, H., Jiang, T., Yu, X. D., Li, S. H., Ye, Q., Zhu, S. Y., Wang, H. J., Zhang, Y., Ma, J., Yu, Y. X., Liu, Z. Y., Li, Y. H., Qin, E. D., Shi, P. Y. & Qin, C. F., Dec 2013, In: Journal of virology. 87, 24, p. 13694-13705 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Vaccines
  • Japanese encephalitis virus
  • Japanese Encephalitis Virus
  • Dengue virus
  • Dengue Virus
  43 Scopus citations

• A cocrystal structure of dengue capsid protein in complex of inhibitor

  Xia, H., Xie, X., Zou, J., Noble, C. G., Russell, W. K., Holthauzen, L. M. F., Choi, K. H., White, M. A. & Shi, P. Y., Jul 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 30, p. 17992-18001 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Dengue
  • Capsid Proteins
  • Capsid
  • Serogroup

• A crystal structure of the dengue virus non-structural protein 5 (NS5) polymerase delineates interdomain amino acid residues that enhance its thermostability and de novo initiation activities

  Lim, S. P., Koh, J. H. K., Seh, C. C., Liew, C. W., Davidson, A. D., Chua, L. S., Chandrasekaran, R., Cornvik, T. C., Shi, P. Y. & Lescar, J., Oct 25 2013, In: Journal of Biological Chemistry. 288, 43, p. 31105-31114 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Viral Structural Proteins
  • RNA Replicase
  • Crystal structure
  • Dengue Virus
  • Viruses
  55 Scopus citations

• Activation of peripheral blood mononuclear cells by dengue virus infection depotentiates balapiravir

  Chen, Y. L., Ghafar, N. A., Karuna, R., Fu, Y., Lim, S. P., Schul, W., Gu, F., Herve, M., Yokohama, F., Wang, G., Cerny, D., Fink, K., Blasco, F. & Shi, P. Y., Feb 2014, In: Journal of virology. 88, 3, p. 1740-1747 8 p.

  Research output: Contribution to journal › Article › peer-review

  • balapiravir
  • 4'-azidocytidine
  • Dengue virus
  • Dengue Virus
  • mononuclear leukocytes
  37 Scopus citations

• A fluorescence-based alkaline phosphatase-coupled polymerase assay for identification of inhibitors of dengue virus RNA-Dependent RNA polymerase

  Niyomrattanakit, P., Abas, S. N., Lim, C. C., Beer, D., Shi, P. Y. & Chen, Y. L., Feb 2011, In: Journal of Biomolecular Screening. 16, 2, p. 201-210 10 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Replicase
  • Dengue Virus
  • Viruses
  • Assays
  • Fluorescence
  39 Scopus citations

• A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation

  Muruato, A. E., Fontes-Garfias, C. R., Ren, P., Garcia-Blanco, M. A., Menachery, V., Xie, X. & Shi, P. Y., May 22 2020, In: Unknown Journal.

  Research output: Contribution to journal › Article › peer-review

  • SARS Virus
  • neutralization tests
  • Assays
  • neutralizing antibodies
  • Neutralizing Antibodies

• A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation

  Muruato, A. E., Fontes-Garfias, C. R., Ren, P., Garcia-Blanco, M. A., Menachery, V. D., Xie, X. & Shi, P. Y., Dec 1 2020, In: Nature communications. 11, 1, 4059.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • vaccines
  • SARS Virus
  • antibodies
  • Assays
  • Neutralizing Antibodies
  18 Scopus citations

• A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models

  Shan, C., Muruato, A. E., Nunes, B. T. D., Luo, H., Xie, X., Medeiros, D. B. A., Wakamiya, M., Tesh, R. B., Barrett, A. D., Wang, T., Weaver, S. C., Vasconcelos, P. F. C., Rossi, S. L. & Shi, P. Y., Jun 1 2017, In: Nature Medicine. 23, 6, p. 763-767 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Viruses
  • Immunity
  • Vaccines
  • Epidemics
  157 Scopus citations

• A multidimensional platform for the purification of non-coding RNA species

  Chionh, Y. H., Ho, C. H., Pruksakorn, D., Ramesh Babu, I., Ng, C. S., Hia, F., McBee, M. E., Su, D., Pang, Y. L. J., Gu, C., Dong, H., Prestwich, E. G., Shi, P. Y., Preiser, P. R., Alonso, S. & Dedon, P. C., Sep 2013, In: Nucleic acids research. 41, 17, p. e168

  Research output: Contribution to journal › Article › peer-review

  • Untranslated RNA
  • Ribonucleosides
  • Viral Genome
  • RNA
  • Plasmodium
  26 Scopus citations

• A Multiplex Microsphere Immunoassay for Zika Virus Diagnosis

  Wong, S. J., Furuya, A., Zou, J., Xie, X., Dupuis, A. P., Kramer, L. D. & Shi, P. Y., Feb 1 2017, In: EBioMedicine. 16, p. 136-140 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Microspheres
  • Viruses
  • Immunoassay
  • Zika Virus Infection
  57 Scopus citations

• A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19

  Xie, X., Muruato, A. E., Zhang, X., Lokugamage, K. G., Fontes-Garfias, C. R., Zou, J., Liu, J., Ren, P., Balakrishnan, M., Cihlar, T., Tseng, C. T. K., Makino, S., Menachery, V. D., Bilello, J. P. & Shi, P. Y., Dec 1 2020, In: Nature communications. 11, 1, 5214.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus
  • Coronavirus
  • drugs
  • Screening
  • screening
  2 Scopus citations

• An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

  Xia, H., Luo, H., Shan, C., Muruato, A. E., Nunes, B. T. D., Medeiros, D. B. A., Zou, J., Xie, X., Giraldo, M. I., Vasconcelos, P. F. C., Weaver, S. C., Wang, T., Rajsbaum, R. & Shi, P. Y., Dec 1 2018, In: Nature communications. 9, 1, 414.

  Research output: Contribution to journal › Article › peer-review

  • interferon
  • Zika Virus
  • viruses
  • Viruses
  • mutations
  93 Scopus citations

• An Infectious cDNA Clone of SARS-CoV-2

  Xie, X., Muruato, A., Lokugamage, K. G., Narayanan, K., Zhang, X., Zou, J., Liu, J., Schindewolf, C., Bopp, N. E., Aguilar, P. V., Plante, K. S., Weaver, S. C., Makino, S., LeDuc, J. W., Menachery, V. D. & Shi, P. Y., May 13 2020, In: Cell Host and Microbe. 27, 5, p. 841-848.e3

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Clone Cells
  • SARS Virus
  • DNA
  53 Scopus citations

• A novel reporter system for neutralizing and enhancing antibody assay against dengue virus

  Song, K. Y., Zhao, H., Jiang, Z. Y., Li, X. F., Deng, Y. Q., Jiang, T., Zhu, S. Y., Shi, P. Y., Zhang, B., Zhang, F. C., Qin, E. D. & Qin, C. F., Feb 18 2014, In: BMC Microbiology. 14, 1, 44.

  Research output: Contribution to journal › Article › peer-review

  • Blocking Antibodies
  • Dengue Virus
  • Neutralizing Antibodies
  • Antibody-Dependent Enhancement
  • Virus Diseases
  12 Scopus citations

• Anti-dengue-virus activity and structure-activity relationship studies of lycorine derivatives

  Wang, P., Li, L. F., Wang, Q. Y., Shang, L. Q., Shi, P. Y. & Yin, Z., Jul 2014, In: ChemMedChem. 9, 7, p. 1522-1533 12 p.

  Research output: Contribution to journal › Article › peer-review

  • lycorine
  • Viral Structures
  • Dengue Virus
  • Structure-Activity Relationship
  • Viruses
  31 Scopus citations

• A positively selected mutation in the WNV 2K peptide confers resistance to superinfection exclusion in vivo

  Campbell, C. L., Smith, D. R., Sanchez-Vargas, I., Zhang, B., Shi, P. Y. & Ebel, G. D., Sep 2014, In: Virology. 464-465, 1, p. 228-232 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Superinfection
  • Culicidae
  • Flaviviridae
  • Culex
  • Viruses
  12 Scopus citations

• A Rapid Zika Diagnostic Assay to Measure Neutralizing Antibodies in Patients

  Shan, C., Xie, X., Ren, P., Loeffelholz, M. J., Yang, Y., Furuya, A., Dupuis, A. P., Kramer, L. D., Wong, S. J. & Shi, P. Y., Mar 1 2017, In: EBioMedicine. 17, p. 157-162 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Viruses
  • Assays
  • Neutralizing Antibodies
  • Zika Virus Infection
  • Neutralization Tests
  44 Scopus citations

• A replication-defective Japanese encephalitis virus (JEV) vaccine candidate with NS1 deletion confers dual protection against JEV and West Nile virus in mice

  Li, N., Zhang, Z. R., Zhang, Y. N., Liu, J., Deng, C. L., Shi, P. Y., Yuan, Z. M., Ye, H. Q. & Zhang, B., Dec 1 2020, In: npj Vaccines. 5, 1, 73.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Japanese Encephalitis Virus
  • West Nile virus
  • Vaccines
  • Flavivirus
  • West Nile Virus Vaccines

• A single amino acid in nonstructural protein NS4B Confers virulence to dengue virus in AG129 mice through enhancement of viral RNA synthesis

  Grant, D., Tan, G. K., Qing, M., Ng, J. K. W., Yip, A., Zou, G., Xie, X., Yuan, Z. Y., Schreiber, J., Schul, W., Shi, P. Y. & Alonso, S., Aug 2011, In: Journal of virology. 85, 15, p. 7775-7787 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • dengue
  • Dengue Virus
  • Dengue
  • Viral RNA
  67 Scopus citations

• A Single Amino Acid Substitution in the Core Protein of West Nile Virus Increases Resistance to Acidotropic Compounds

  Martín-Acebes, M. A., Blázquez, A. B., de Oya, N. J., Escribano-Romero, E., Shi, P. Y. & Saiz, J. C., Jul 18 2013, In: PloS one. 8, 7, e69479.

  Research output: Contribution to journal › Article › peer-review

  • West Nile virus
  • Viruses
  • Amino Acid Substitution
  • amino acid substitution
  • Substitution reactions
  10 Scopus citations

• A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

  Shan, C., Muruato, A. E., Jagger, B. W., Richner, J., Nunes, B. T. D., Medeiros, D. B. A., Xie, X., Nunes, J. G. C., Morabito, K. M., Kong, W. P., Pierson, T. C., Barrett, A. D., Weaver, S. C., Rossi, S. L., Vasconcelos, P. F. C., Graham, B. S., Diamond, M. S. & Shi, P. Y., Dec 1 2017, In: Nature communications. 8, 1, 676.

  Research output: Contribution to journal › Article › peer-review

  • vaccines
  • testes
  • pregnancy
  • Zika Virus
  • Attenuated Vaccines
  80 Scopus citations

• A Single-Dose Live-Attenuated Zika Virus Vaccine with Controlled Infection Rounds that Protects against Vertical Transmission

  Xie, X., Kum, D. B., Xia, H., Luo, H., Shan, C., Zou, J., Muruato, A. E., Medeiros, D. B. A., Nunes, B. T. D., Dallmeier, K., Rossi, S. L., Weaver, S. C., Neyts, J., Wang, T., Vasconcelos, P. F. C. & Shi, P. Y., Oct 10 2018, In: Cell Host and Microbe. 24, 4, p. 487-499.e5

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Vaccines
  • Infection
  • Attenuated Vaccines
  • Capsid Proteins
  22 Scopus citations

• A single-dose plasmid-launched live-attenuated Zika vaccine induces protective immunity

  Zou, J., Xie, X., Luo, H., Shan, C., Muruato, A. E., Weaver, S. C., Wang, T. & Shi, P. Y., Oct 2018, In: EBioMedicine. 36, p. 92-102 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Attenuated Vaccines
  • Immunity
  • Plasmids
  • Vaccines
  • DNA
  21 Scopus citations

• A single mutation in the prM protein of Zika virus contributes to fetal microcephaly

  Yuan, L., Huang, X. Y., Liu, Z. Y., Zhang, F., Zhu, X. L., Yu, J. Y., Ji, X., Xu, Y. P., Li, G., Li, C., Wang, H. J., Deng, Y. Q., Wu, M., Cheng, M. L., Ye, Q., Xie, D. Y., Li, X. F., Wang, X., Shi, W., Hu, B. & 3 others, Shi, P. Y., Xu, Z. & Qin, C. F., Nov 17 2017, In: Science. 358, 6365, p. 933-936 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Microcephaly
  • Mutation
  • Epidemics
  • Polynesia
  211 Scopus citations

• A translation inhibitor that suppresses dengue virus in vitro and in vivo

  Wang, Q. Y., Kondreddi, R. R., Xie, X., Rao, R., Nilar, S., Xu, H. Y., Qing, M., Chang, D., Dong, H., Yokokawa, F., Lakshminarayana, S. B., Goh, A., Schul, W., Kramer, L., Keller, T. H. & Shi, P. Y., Sep 2011, In: Antimicrobial agents and chemotherapy. 55, 9, p. 4072-4080 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Benzomorphans
  • Viral RNA
  • In Vitro Techniques
  • Pharmacokinetics
  39 Scopus citations

• A Zika virus envelope mutation preceding the 2015 epidemic enhances virulence and fitness for transmission

  Shan, C., Xia, H., Haller, S. L., Azar, S. R., Liu, Y., Liu, J., Muruato, A. E., Chen, R., Rossi, S. L., Wakamiya, M., Vasilakis, N., Pei, R., Fontes-Garfias, C. R., Singh, S. K., Xie, X., Weaver, S. C. & Shi, P. Y., Aug 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 33, p. 20190-20197 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Viremia
  • Virulence
  • Epidemics
  • Mutation
  6 Scopus citations

• A Zika virus vaccine expressing premembrane-envelope-NS1 polyprotein

  Li, A., Yu, J., Lu, M., Ma, Y., Attia, Z., Shan, C., Xue, M., Liang, X., Craig, K., Makadiya, N., He, J. J., Jennings, R., Shi, P. Y., Peeples, M. E., Liu, S. L., Boyaka, P. N. & Li, J., Dec 1 2018, In: Nature communications. 9, 1, 3067.

  Research output: Contribution to journal › Article › peer-review

  • vaccines
  • Zika Virus
  • Polyproteins
  • viruses
  • Viruses
  24 Scopus citations

• Characterization of a candidate tetravalent vaccine based on 2’-O-methyltransferase mutants

  Züst, R., Li, S. H., Xie, X., Velumani, S., Chng, M., Toh, Y. X., Zou, J., Dong, H., Shan, C., Pang, J., Qin, C. F., Newell, E. W., Shi, P. Y. & Fink, K., Jan 2018, In: PloS one. 13, 1, e0189262.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Dengue Virus
  • Viruses
  • Methyltransferases
  • methyltransferases
  4 Scopus citations

• Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo

  Chang, J., Schul, W., Butters, T. D., Yip, A., Liu, B., Goh, A., Lakshminarayana, S. B., Alonzi, D., Reinkensmeier, G., Pan, X., Qu, X., Weidner, J. M., Wang, L., Yu, W., Borune, N., Kinch, M. A., Rayahin, J. E., Moriarty, R., Xu, X., Shi, P. Y. & 2 others, Guo, J. T. & Block, T. M., Jan 2011, In: Antiviral research. 89, 1, p. 26-34 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Glucosidases
  • Dengue Virus
  • Ribavirin
  • 4-nitrophenyl-alpha-glucosidase
  • glucosidase I
  67 Scopus citations

• Conformational flexibility of the dengue virus RNA-Dependent RNA polymerase revealed by a complex with an inhibitor

  Noble, C. G., Lim, S. P., Chen, Y. L., Liew, C. W., Yap, L., Lescar, J. & Shi, P. Y., May 2013, In: Journal of virology. 87, 9, p. 5291-5295 5 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Replicase
  • Dengue virus
  • RNA-directed RNA polymerase
  • Dengue Virus
  • Serogroup
  70 Scopus citations

• Construction of stable reporter flaviviruses and their applications

  Baker, C. & Shi, P. Y., Oct 2020, In: Viruses. 12, 10, 1082.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Flavivirus
  • Epidemics
  • Antiviral Agents
  • Vaccines
  • Viruses

• COVID-19 vaccine BNT162b1 elicits human antibody and T_H1 T cell responses

  Sahin, U., Muik, A., Derhovanessian, E., Vogler, I., Kranz, L. M., Vormehr, M., Baum, A., Pascal, K., Quandt, J., Maurus, D., Brachtendorf, S., Lörks, V., Sikorski, J., Hilker, R., Becker, D., Eller, A. K., Grützner, J., Boesler, C., Rosenbaum, C., Kühnle, M. C. & 22 others, Luxemburger, U., Kemmer-Brück, A., Langer, D., Bexon, M., Bolte, S., Karikó, K., Palanche, T., Fischer, B., Schultz, A., Shi, P. Y., Fontes-Garfias, C., Perez, J. L., Swanson, K. A., Loschko, J., Scully, I. L., Cutler, M., Kalina, W., Kyratsous, C. A., Cooper, D., Dormitzer, P. R., Jansen, K. U. & Türeci, Ö., Oct 22 2020, In: Nature. 586, 7830, p. 594-599 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Coronavirus
  • Th1 Cells
  • Vaccines
  • Severe Acute Respiratory Syndrome
  • Antibodies
  40 Scopus citations

• Crystal structure of dengue virus methyltransferase without S-adenosyl-L-methionine

  Noble, C. G., Li, S. H., Dong, H., Chew, S. H. & Shi, P. Y., Nov 2014, In: Antiviral research. 111, p. 78-81 4 p.

  Research output: Contribution to journal › Article › peer-review

  • S-Adenosylmethionine
  • Dengue Virus
  • Methyltransferases
  • Enzymes
  • Flavivirus
  11 Scopus citations

• Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: Implication for a trans mechanism of VPg uridylylation

  Chen, C., Wang, Y., Shan, C., Sun, Y., Xu, P., Zhou, H., Yang, C., Shi, P. Y., Rao, Z., Zhang, B. & Lou, Z., May 1 2013, In: Journal of virology. 87, 10, p. 5755-5768 14 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Replicase
  • RNA-directed RNA polymerase
  • Enterovirus
  • crystal structure
  • Picornaviridae
  45 Scopus citations

• Dengue in China: not a passing problem

  Qin, C. F. & Shi, P. Y., Dec 11 2014, In: Science China Life Sciences. 57, 12, p. 1230-1231 2 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission

  Pompon, J., Manuel, M., Ng, G. K., Wong, B., Shan, C., Manokaran, G., Soto-Acosta, R., Bradrick, S. S., Ooi, E. E., Missé, D., Shi, P. Y. & Garcia-Blanco, M. A., Jul 2017, In: PLoS pathogens. 13, 7, e1006535.

  Research output: Contribution to journal › Article › peer-review

  • Dengue
  • Culicidae
  • Salivary Glands
  • Immunity
  • RNA
  47 Scopus citations

• Dengue Therapeutics, Chemoprophylaxis, and Allied Tools: State of the Art and Future Directions

  Whitehorn, J., Yacoub, S., Anders, K. L., Macareo, L. R., Cassetti, M. C., Nguyen Van, V. C., Shi, P. Y., Wills, B. & Simmons, C. P., Aug 28 2014, In: PLoS neglected tropical diseases. 8, 8, e3025.

  Research output: Contribution to journal › Article › peer-review

  • Dengue
  • Chemoprevention
  • Direction compound
  • Drug Discovery
  • Dengue Virus
  47 Scopus citations

• Design, synthesis and biological evaluation of spiropyrazolopyridone derivatives as potent dengue virus inhibitors

  Xu, J., Xie, X., Chen, H., Zou, J., Xue, Y., Ye, N., Shi, P. Y. & Zhou, J., Jun 1 2020, In: Bioorganic and Medicinal Chemistry Letters. 30, 11, 127162.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Viruses
  • Substitution reactions
  • Nitrogen
  • Derivatives

• Development and characterization of a stable eGFP enterovirus 71 for antiviral screening

  Shang, B., Deng, C., Ye, H., Xu, W., Yuan, Z., Shi, P. Y. & Zhang, B., Feb 2013, In: Antiviral research. 97, 2, p. 198-205 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Enterovirus
  • Antiviral Agents
  • Viruses
  • Vero Cells
  • Complementary DNA
  32 Scopus citations

• Development and characterization of a stable luciferase dengue virus for high-throughput screening

  Zou, G., Xu, H. Y., Qing, M., Wang, Q. Y. & Shi, P. Y., Jul 1 2011, In: Antiviral research. 91, 1, p. 11-19 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Luciferases
  • Viruses
  • Complementary DNA
  • Renilla Luciferases
  83 Scopus citations

• Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone

  Li, X. F., Dong, H. L., Wang, H. J., Huang, X. Y., Qiu, Y. F., Ji, X., Ye, Q., Li, C., Liu, Y., Deng, Y. Q., Jiang, T., Cheng, G., Zhang, F. C., Davidson, A. D., Song, Y. J., Shi, P. Y. & Qin, C. F., Dec 1 2018, In: Nature communications. 9, 1, 673.

  Research output: Contribution to journal › Article › peer-review

  • vaccines
  • Zika Virus
  • Flavivirus
  • Attenuated Vaccines
  • viruses
  45 Scopus citations

• Development of a FACS-based assay for evaluating antiviral potency of compound in dengue infected peripheral blood mononuclear cells

  Fu, Y., Chen, Y. L., Herve, M., Gu, F., Shi, P. Y. & Blasco, F., Feb 2014, In: Journal of Virological Methods. 196, p. 18-24 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Dengue
  • Antiviral Agents
  • Blood Cells
  • Virus Diseases
  4 Scopus citations

• Dimerization of flavivirus NS4B protein

  Zou, J., Xie, X., Lee, L. T., Chandrasekaran, R., Reynaud, A., Yap, L., Wang, Q. Y., Dong, H., Kang, C., Yuan, Z., Lescar, J. & Shi, P. Y., Mar 2014, In: Journal of virology. 88, 6, p. 3379-3391 13 p.

  Research output: Contribution to journal › Article › peer-review

  • flavivirus NS4B protein
  • Flavivirus
  • dimerization
  • Dimerization
  • Dengue virus
  43 Scopus citations

• Dysregulation of Ephrin receptor and PPAR signaling pathways in neural progenitor cells infected by Zika virus

  Thulasi Raman, S. N., Latreille, E., Gao, J., Zhang, W., Wu, J., Russell, M. S., Walrond, L., Cyr, T., Lavoie, J. R., Safronetz, D., Cao, J., Sauve, S., Farnsworth, A., Chen, W., Shi, P. Y., Wang, Y., Wang, L., Rosu-Myles, M. & Li, X., Jan 1 2020, In: Emerging Microbes and Infections. 9, 1, p. 2046-2060 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Eph Family Receptors
  • Zika Virus
  • Neural Pathways
  • Microcephaly
  • Peroxisome Proliferator-Activated Receptors

• Enterovirus 71 VPg uridylation uses a two-molecular mechanism of 3D polymerase

  Sun, Y., Wang, Y., Shan, C., Chen, C., Xu, P., Song, M., Zhou, H., Yang, C., Xu, W., Shi, P. Y., Zhang, B. & Lou, Z., Dec 2012, In: Journal of virology. 86, 24, p. 13662-13671 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Enterovirus
  • Picornaviridae
  • RNA
  • mutation
  • Mutation
  32 Scopus citations

• Envelope protein ubiquitination drives entry and pathogenesis of Zika virus

  Giraldo, M. I., Xia, H., Aguilera-Aguirre, L., Hage, A., van Tol, S., Shan, C., Xie, X., Sturdevant, G. L., Robertson, S. J., McNally, K. L., Meade-White, K., Azar, S. R., Rossi, S. L., Maury, W., Woodson, M., Ramage, H., Johnson, J. R., Krogan, N. J., Morais, M. C., Best, S. M. & 2 others, Shi, P. Y. & Rajsbaum, R., Sep 17 2020, In: Nature. 585, 7825, p. 414-419 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Ubiquitination
  • Virus Internalization
  • Polyubiquitin
  • Proteins
  6 Scopus citations

• Evaluation of a novel reporter virus neutralization test for serological diagnosis of Zika and Dengue virus infection

  Shan, C., Ortiz, D. A., Yang, Y., Wong, S. J., Kramer, L. D., Shi, P. Y., Loeffelholz, M. J. & Ren, P., Oct 2017, In: Journal of Clinical Microbiology. 55, 10, p. 3028-3036 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus Infection
  • Zika Virus
  • Neutralization Tests
  • Dengue Virus
  • Viruses
  23 Scopus citations

• Evasion of Type I Interferon by SARS-CoV-2

  Xia, H., Cao, Z., Xie, X., Zhang, X., Chen, J. Y. C., Wang, H., Menachery, V. D., Rajsbaum, R. & Shi, P. Y., Oct 6 2020, In: Cell Reports. 33, 1, 108234.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Interferon Type I
  • Phosphorylation
  • Interferon Regulatory Factor-3
  19 Scopus citations