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A biosafety level-2 dose-dependent lethal mouse model of spotted fever rickettsiosis: Rickettsia parkeri atlantic rainforest strain
Londoño, A. F., Mendell, N. L., Walker, D. H. & Bouyer, D. H., Jun 2019, In: PLoS neglected tropical diseases. 13, 6, e0007054.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
A cluster of cases of rocky mountain spotted fever in an area of Colombia not known to be endemic for this disease
Londoño, A. F., Arango-Ferreira, C., Acevedo-Gutiérrez, L. Y., Paternina, L. E., Montes, C., Ruiz, I., Labruna, M. B., Díaz, F. J., Walker, D. H. & Rodas, J. D., 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 2, p. 336-342 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
An animal model of a newly emerging human ehrlichiosis
Saito, T. B., Thirumalapura, N. R., Shelite, T. R., Rockx-Brouwer, D., Popov, V. L. & Walker, D. H., Feb 1 2015, In: Journal of Infectious Diseases. 211, 3, p. 452-461 10 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
An Intradermal Inoculation Mouse Model for Immunological Investigations of Acute Scrub Typhus and Persistent Infection
Soong, L., Mendell, N. L., Olano, J. P., Rockx-Brouwer, D., Xu, G., Goez-Rivillas, Y., Drom, C., Shelite, T. R., Valbuena, G., Walker, D. H. & Bouyer, D. H., Aug 1 2016, In: PLoS neglected tropical diseases. 10, 8, e0004884.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Approaches to vaccines against Orientia tsutsugamushi
Valbuena, G. & Walker, D. H., 2013, In: Frontiers in cellular and infection microbiology. 4, JAN, Article 170.Research output: Contribution to journal › Article › peer-review
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A review of the global epidemiology of scrub typhus
Xu, G., Walker, D. H., Jupiter, D., Melby, P. C. & Arcari, C. M., Nov 3 2017, In: PLoS neglected tropical diseases. 11, 11, e0006062.Research output: Contribution to journal › Article › peer-review
73 Scopus citations -
Atg5 supports Rickettsia australis infection in macrophages in vitro and in vivo
Bechelli, J., Vergara, L., Smalley, C., Buzhdygan, T. P., Bender, S., Zhang, W., Liu, Y., Popov, V. L., Wang, J., Garg, N., Hwang, S., Walker, D. H. & Fang, R., Jan 1 2019, In: Infection and immunity. 87, 1, e00651.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
A Tick Vector Transmission Model of Monocytotropic Ehrlichiosis
Saito, T. B. & Walker, D. H., Sep 15 2015, In: Journal of Infectious Diseases. 212, 6, p. 968-977 10 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Burkholderia pseudomallei ΔtonB Δhcp1 live attenuated vaccine strain elicits full protective immunity against aerosolized melioidosis infection
Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Kilgore, P. B., Ross, B. N., Walker, D. H., Endsley, J. J. & Torresa, A. G., Jan 1 2019, In: mSphere. 4, 1, e00570-18.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Case-Fatality ratio and effectiveness of ribavirin therapy among hospitalized patients in china who had severe fever with thrombocytopenia syndrome
Liu, W., Lu, Q. B., Cui, N., Li, H., Wang, L. Y., Liu, K., Yang, Z. D., Wang, B. J., Wang, H. Y., Zhang, Y. Y., Zhuang, L., Hu, C. Y., Yuan, C., Fan, X. J., Wang, Z., Zhang, L., Zhang, X. A., Walker, D. H. & Cao, W. C., Nov 1 2013, In: Clinical Infectious Diseases. 57, 9, p. 1292-1299 8 p.Research output: Contribution to journal › Article › peer-review
96 Scopus citations -
Case report: An unusual cutaneous manifestation in a patient with murine typhus
Blanton, L. S., Lea, A. S., Kelly, B. C. & Walker, D. H., Dec 2015, In: American Journal of Tropical Medicine and Hygiene. 93, 6, p. 1164-1167 4 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
CD8+T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection
Xu, G., Mendell, N. L., Liang, Y., Shelite, T. R., Goez-Rivillas, Y., Soong, L., Bouyer, D. H. & Walker, D. H., Jul 19 2017, In: PLoS neglected tropical diseases. 11, 7, e0005763.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: Evidence of possible mediation by host tRNA-derived small noncoding RNAs
Gong, B., Lee, Y. S., Lee, I., Shelite, T. R., Kunkeaw, N., Xu, G., Lee, K., Jeon, S. H., Johnson, B. H., Chang, Q., Ha, T., Mendell, N. L., Cheng, X., Bouyer, D. H., Boor, P. J., Ksiazek, T. G. & Walker, D. H., Jun 23 2013, In: BMC Infectious Diseases. 13, 1, 285.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium
Fang, R., Ismail, N. & Walker, D. H., Jul 2012, In: American Journal of Pathology. 181, 1, p. 185-195 11 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Diagnosing emerging and reemerging infectious diseases: The pivotal role of the pathologist
Olano, J. P. & Walker, D. H., Jan 1 2011, In: Archives of Pathology and Laboratory Medicine. 135, 1, p. 83-91 9 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Ehrlichia chaffeensis outer membrane protein 1-specific human antibody-mediated immunity is defined by intracellular TRIM21-dependent innate immune activation and extracellular neutralization
Velayutham, T. S., Kumar, S., Zhang, X., Kose, N., Walker, D. H., Winslow, G., Crowe, J. E. & McBride, J. W., Dec 1 2019, In: Infection and immunity. 87, 12, e00383-19.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Endothelial cell proteomic response to Rickettsia conorii infection reveals activation of the Janus Kinase (JAK)-signal transducer and activator of transcription (STAT)-inferferon stimulated gene (ISG)15 pathway and reprogramming plasma membrane integrin/cadherin signaling
Zhao, Y., Valbuena, G., Walker, D. H., Gazi, M., Hidalgo, M., DeSousa, R., Oteo, J. A., Goez, Y. & Brasier, A. R., Jan 2016, In: Molecular and Cellular Proteomics. 15, 1, p. 289-304 16 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Evaluation of Burkholderia mallei ΔtonB Δhcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis
Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Walker, D. H., Endsley, J. J. & Torres, A. G., Jul 2019, In: PLoS neglected tropical diseases. 13, 7, e0007578.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses
Gong, B., Shelite, T., Mei, F. C., Ha, T., Hu, Y., Xu, G., Chang, Q., Wakamiya, M., Ksiazek, T. G., Boor, P. J., Bouyer, D. H., Popov, V. L., Chen, J., Walker, D. H. & Cheng, X., Nov 26 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 48, p. 19615-19620 6 p.Research output: Contribution to journal › Article › peer-review
48 Scopus citations -
Fatal monocytic ehrlichiosis in woman, Mexico, 2013
Sosa-Gutierrez, C. G., Solorzano-Santos, F., Walker, D. H., Torres, J., Serrano, C. A. & Gordillo-Perez, G., May 2016, In: Emerging infectious diseases. 22, 5, p. 871-874 4 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Fever and rash after a safari
Damavandy, A. A., Rojek, N. W., Dugan, E. M., Walker, D. & Norton, S. A., Jan 1 2015, In: Journal of the American Academy of Dermatology. 72, 1, p. e5-e6Research output: Contribution to journal › Article › peer-review
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Fever with thrombocytopenia associated with a novel bunyavirus in China
Yu, X. J., Liang, M. F., Zhang, S. Y., Liu, Y., Li, J. D., Sun, Y. L., Zhang, L., Zhang, Q. F., Popov, V. L., Li, C., Qu, J., Li, Q., Zhang, Y. P., Hai, R., Wu, W., Wang, Q., Zhan, F. X., Wang, X. J., Kan, B., Wang, S. W. & 26 others, , Apr 21 2011, In: New England Journal of Medicine. 364, 16, p. 1523-1532 10 p.Research output: Contribution to journal › Article › peer-review
756 Scopus citations -
Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium
Sahni, A., Patel, J., Narra, H. P., Schroeder, C. L. C., Walker, D. H. & Sahni, S. K., Aug 2017, In: PloS one. 12, 8, e0183181.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Genotypic characterization of Orientia tsutsugamushi from patients in two geographical locations in Sri Lanka
Premaratna, R., Blanton, L. S., Samaraweera, D. N., de Silva, G. N. N., Chandrasena, N. T. G. A., Walker, D. H. & de Silva, H. J., Jan 13 2017, In: BMC Infectious Diseases. 17, 1, 67.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Immune Mediators of protective and pathogenic immune responses in patients with mild and fatal human monocytotropic ehrlichiosis
Ismail, N., Walker, D. H., Ghose, P. & Tang, Y. W., May 21 2012, In: BMC Immunology. 13, 26.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Immunization with Ehrlichia P28 outer membrane proteins confers protection in a mouse model of ehrlichiosis
Crocquet-Valdes, P. A., Thirumalapura, N. R., Ismail, N., Yu, X., Saito, T. B., Stevenson, H. L., Pietzsch, C. A., Thomas, S. & Walker, D. H., Dec 2011, In: Clinical and Vaccine Immunology. 18, 12, p. 2018-2025 8 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Mechanisms of immunity to rickettsia and implications for vaccine development
Walker, D., Jan 1 2017, In: Revista Colombiana de Ciencias Pecuarias. 30, p. 262-263 2 p.Research output: Contribution to journal › Article › peer-review
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Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus
Yun, N. E., Seregin, A. V., Walker, D. H., Popov, V. L., Walker, A. G., Smith, J. N., Miller, M., de la Torre, J. C., Smith, J. K., Borisevich, V., Fair, J. N., Wauquier, N., Grant, D. S., Bockarie, B., Bente, D. & Paessler, S., 2013, In: Journal of virology. 87, 19, p. 10908-10911 4 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Molecular and cellular pathobiology of Ehrlichia infection: Targets for new therapeutics and immunomodulation strategies
McBride, J. W. & Walker, D. H., Jan 2011, In: Expert reviews in molecular medicine. 13, e3.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
Murine models of scrub typhus associated with host control of Orientia tsutsugamushi infection
Mendell, N. L., Bouyer, D. H. & Walker, D. H., Mar 10 2017, In: PLoS neglected tropical diseases. 11, 3, e0005453.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
MyD88 mediates instructive signaling in dendritic cells and protective inflammatory response during rickettsial infection
Bechelli, J., Smalley, C., Zhao, X., Judy, B., Valdes, P., Walker, D. H. & Fang, R., Apr 1 2016, In: Infection and immunity. 84, 4, p. 883-893 11 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Obligate intracellular bacterium Ehrlichia inhibiting mitochondrial activity
Liu, Y., Zhang, Z., Jiang, Y., Zhang, L., Popov, V. L., Zhang, J., Walker, D. H. & Yu, X. J., Mar 2011, In: Microbes and Infection. 13, 3, p. 232-238 7 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Opossums and cat fleas: New insights in the ecology of murine typhus in Galveston, Texas
Blanton, L. S., Idowu, B. M., Tatsch, T. N., Henderson, J. M., Bouyer, D. H. & Walker, D. H., Aug 2016, In: American Journal of Tropical Medicine and Hygiene. 95, 2, p. 457-461 5 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
Pathogenesis of Rickettsial Diseases: Pathogenic and Immune Mechanisms of an Endotheliotropic Infection
Sahni, A., Fang, R., Sahni, S. K. & Walker, D. H., 2019, In: Annual Review of Pathology: Mechanisms of Disease. 14, p. 127-152 26 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Permissive and protective roles for neutrophils in leishmaniasis
Carlsen, E. D., Liang, Y., Shelite, T. R., Walker, D. H., Melby, P. C. & Soong, L., Nov 2015, In: Clinical and Experimental Immunology. 182, 2, p. 109-18 10 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Person-to-person transmission of severe fever with thrombocytopenia syndrome virus
Liu, Y., Li, Q., Hu, W., Wu, J., Weng, Y., Mei, L., Walker, D. H., Ren, J., Wang, Y. & Yu, X. J., Feb 1 2012, In: Vector-Borne and Zoonotic Diseases. 12, 2, p. 156-160 5 p.Research output: Contribution to journal › Article › peer-review
154 Scopus citations -
Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis
Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In: Vaccine. 31, 50, p. 5960-5967 8 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Reemergence of murine typhus in galveston, texas, usa, 2013
Blanton, L. S., Vohra, R. F., Bouyer, D. H. & Walker, D. H., 2015, In: Emerging infectious diseases. 21, 3, p. 484-486 3 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
Rickettsia australis activates inflammasome in human and murine macrophages
Smalley, C., Bechelli, J., Rockx-Brouwer, D., Saito, T., Azar, S. R., Ismail, N., Walker, D. H. & Fang, R., Jun 2016, In: PloS one. 11, 6, e0157231.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Rickettsiae Within the Fleas of Feral Cats in Galveston, Texas
Blanton, L. S., Vohra, R. F., Fistein, L., Quade, B., Walker, D. H. & Bouyer, D. H., Sep 2019, In: Vector-Borne and Zoonotic Diseases. 19, 9, p. 647-651 5 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Rickettsia massiliae and rickettsia conorii israeli spotted fever strain differentially regulate endothelial cell responses
Bechelli, J., Smalley, C., Milhano, N., Walker, D. H. & Fang, R., Sep 22 2015, In: PloS one. 10, 9, e0138830.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Simple method to differentiate among Rickettsia species
Peniche-Lara, G., Zavala-Velazquez, J., Dzul-Rosado, K., Walker, D. H. & Zavala-Castro, J., Apr 1 2013, In: Journal of Molecular Microbiology and Biotechnology. 23, 3, p. 203-208 6 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Spotted fever group Rickettsia in small rodents from areas of low endemicity for Brazilian spotted fever in the Eastern Region of Minas Gerais State, Brazil
Milagres, B. S., Padilha, A. F., Montandon, C. E., Freitas, R. N., Pacheco, R., Walker, D. H., Labruna, M. B., Mafra, C. L. & Galvão, M. A. M., May 2013, In: American Journal of Tropical Medicine and Hygiene. 88, 5, p. 937-939 3 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Structure-based vaccines provide protection in a mouse model of ehrlichiosis
Thomas, S., Thirumalapura, N. R., Crocquet-Valdes, P. A., Luxon, B. A. & Walker, D. H., Nov 17 2011, In: PloS one. 6, 11, e27981.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Susceptibility of Rickettsia rickettsii to Tigecycline in a Cell Culture Assay and Animal Model for Rocky Mountain Spotted Fever
Blanton, L. S., Wilson, N. M., Quade, B. R. & Walker, D. H., 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 5, p. 1091-1095 5 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Systemic treatment with cpg-b after sublethal rickettsial infection induces mouse death through indoleamine 2,3-dioxygenase (ido)
Xin, L., Shelite, T. R., Gong, B., Mendell, N. L., Soong, L., Fang, R. & Walker, D. H., Mar 28 2012, In: PloS one. 7, 3, e34062.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
The role of Rhipicephalus sanguineus sensu lato saliva in the dissemination of Rickettsia conorii in C3H/HeJ mice
Milhano, N., Saito, T. B., Bechelli, J., Fang, R., Vilhena, M., De Sousa, R. & Walker, D. H., Sep 1 2015, In: Medical and Veterinary Entomology. 29, 3, p. 225-229 5 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Time to Worry about Anthrax Again
Keim, P. S., Walker, D. H. & Zilinskas, R. A., Mar 14 2017, In: Scientific American. 316, 4, p. 70-75 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Value of autopsy emphasized in the case report of a single patient with middle east respiratory syndrome
Walker, D. H., Mar 1 2016, In: American Journal of Pathology. 186, 3, p. 507-510 4 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Vector Tick Transmission Model of Spotted Fever Rickettsiosis
Saito, T. B., Bechelli, J., Smalley, C., Karim, S. & Walker, D. H., Jan 2019, In: American Journal of Pathology. 189, 1, p. 115-123 9 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations