Find Research Outputs

Search results

• Article

  A FRET-Based DNA Biosensor Tracks OmpR-Dependent Acidification of Salmonella during Macrophage Infection

  Chakraborty, S., Mizusaki, H. & Kenney, L. J., Apr 14 2015, In: PLoS Biology. 13, 4, e1002116.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Macrophages
  • Salmonella
  • Forster resonance energy transfer
  • Acidification
  • Biosensing Techniques
  54 Scopus citations

• An escherichia coli nissle 1917 missense mutant colonizes the streptomycin-treated mouse intestine better than the wild type but is not a better probiotic

  Adediran, J., Leatham-Jensen, M. P., Mokszycki, M. E., Frimodt-Møller, J., Krogfelt, K. A., Kazmierczak, K., Kenney, L. J., Conway, T. & Cohena, P. S., Feb 2014, In: Infection and immunity. 82, 2, p. 670-682 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Streptomycin
  • Probiotics
  • Intestines
  • Escherichia coli
  • Mucus
  21 Scopus citations

• A new role of OmpR in acid and osmotic stress in salmonella and E. coli

  Chakraborty, S. & Kenney, L. J., Nov 22 2018, In: Frontiers in Microbiology. 9, NOV, 2656.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Osmotic Pressure
  • Salmonella
  • Acids
  • Escherichia coli
  • Regulon
  15 Scopus citations

• A single molecule analysis of H-NS uncouples DNA binding affinity from DNA specificity

  Gulvady, R., Gao, Y., Kenney, L. J. & Yan, J., 2018, In: Nucleic acids research. 46, 19, p. 10216-10224 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA-Binding Proteins
  • Hot Temperature
  • DNA
  • Proteins
  • Gene Silencing
  12 Scopus citations

• Engineered oligomerization state of OmpF protein through computational design decouples oligomer dissociation from unfolding

  Naveed, H., Jimenez-Morales, D., Tian, J., Pasupuleti, V., Kenney, L. J. & Liang, J., May 25 2012, In: Journal of Molecular Biology. 419, 1-2, p. 89-101 13 p.

  Research output: Contribution to journal › Article › peer-review

  • OmpF protein
  • Proteins
  • Porins
  • Bacterial Outer Membrane Proteins
  • Membrane Proteins
  20 Scopus citations

• Engineering an Osmosensor by Pivotal Histidine Positioning within Disordered Helices

  Ghosh, M., Wang, L. C., Huber, R. G., Gao, Y., Morgan, L. K., Tulsian, N. K., Bond, P. J., Kenney, L. J. & Anand, G. S., Feb 5 2019, In: Structure. 27, 2, p. 302-314.e4

  Research output: Contribution to journal › Article › peer-review

  • Histidine
  • Histidine Kinase
  • Phosphorylation
  2 Scopus citations

• Gene silencing H-NS paralogue StpA forms a rigid protein filament along DNA that blocks DNA accessibility

  Lim, C. J., Whang, Y. R., Kenney, L. J. & Yan, J., Apr 2012, In: Nucleic acids research. 40, 8, p. 3316-3328 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gene Silencing
  • Histones
  • DNA
  • Proteins
  • DNA Packaging
  48 Scopus citations

• Identification of Biofilm Inhibitors by Screening Combinatorial Libraries of Metal Oxide Thin Films

  Dykas, M. M., Desai, S. K., Patra, A., Motapothula, M. R., Poddar, K., Kenney, L. J. & Venkatesan, T., Apr 18 2018, In: ACS Applied Materials and Interfaces. 10, 15, p. 12510-12517 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Biofilms
  • Oxide films
  • Oxides
  • Thin films
  • Screening
  3 Scopus citations

• New variant of multidrug-resistant Salmonella enterica serovar typhimurium associated with invasive disease in immunocompromised patients in Vietnam

  Mather, A. E., Phuong, T. L. T., Gao, Y., Clare, S., Mukhopadhyay, S., Goulding, D. A., Do Hoang, N. T., Tuyen, H. T., Lan, N. P. H., Thompson, C. N., Trang, N. H. T., Carrique-Mas, J., Tue, N. T., Campbell, J. I., Rabaa, M. A., Thanh, D. P., Harcourt, K., Hoa, N. T., Trung, N. V., Schultsz, C. & 12 others, Perron, G. G., Coia, J. E., Brown, D. J., Okoro, C., Parkhill, J., Thomson, N. R., Chau, N. V. V., Thwaites, G. E., Maskell, D. J., Dougan, G., Kenney, L. J. & Baker, S., Sep 1 2018, In: mBio. 9, 5, e01056-18.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Salmonella enterica
  • Vietnam
  • Immunocompromised Host
  • Salmonella
  • Serogroup
  14 Scopus citations

• Nucleoprotein filament formation is the structural basis for bacterial protein H-NS gene silencing

  Lim, C. J., Lee, S. Y., Kenney, L. J. & Yan, J., 2012, In: Scientific reports. 2, 509.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nucleoproteins
  • Bacterial Proteins
  • Gene Silencing
  • Genes
  • Bacteria
  63 Scopus citations

• Rapid, High-Throughput Tracking of Bacterial Motility in 3D via Phase-Contrast Holographic Video Microscopy

  Cheong, F. C., Wong, C. C., Gao, Y., Nai, M. H., Cui, Y., Park, S., Kenney, L. & Lim, C. T., Mar 10 2015, In: Biophysical Journal. 108, 5, p. 1248-1256 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Video Microscopy
  • Bacteria
  • Agrobacterium tumefaciens
  • Lab-On-A-Chip Devices
  • Swimming
  14 Scopus citations

• Salmonella biofilms program innate immunity for persistence in Caenorhabditis elegans

  Desai, S. K., Padmanabhan, A., Harshe, S., Zaidel-Bar, R. & Kenney, L. J., Jun 18 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 25, p. 12462-12467 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Caenorhabditis elegans
  • Salmonella
  • Biofilms
  • Innate Immunity
  • Life Style
  8 Scopus citations

• Salmonella enterica response regulator SsrB relieves H-NS silencing by displacing H-NS bound in polymerization mode and directly activates transcription

  Walthers, D., Li, Y., Liu, Y., Anand, G., Yan, J. & Kenney, L. J., Jan 21 2011, In: Journal of Biological Chemistry. 286, 3, p. 1895-1902 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Salmonella
  • Salmonella enterica
  • Transcription
  • Polymerization
  • Genes
  64 Scopus citations

• Single cell, super-resolution imaging reveals an acid pH-dependent conformational switch in SsrB regulates SPI-2

  Liew, A. T. F., Foo, Y. H., Gao, Y., Zangoui, P., Singh, M. K., Gulvady, R. & Kenney, L. J., Apr 2019, In: eLife. 8, e45311.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Salmonella
  • Imaging techniques
  • Acids
  • Switches
  • DNA
  5 Scopus citations

• Single cell super-resolution imaging of E. coli OmpR during environmental stress

  Foo, Y. H., Spahn, C., Zhang, H., Heilemann, M. & Kenney, L. J., Oct 1 2015, In: Integrative Biology (United Kingdom). 7, 10, p. 1297-1308 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Escherichia coli
  • Membranes
  • Imaging techniques
  • Chromosomes
  • DNA-Directed RNA Polymerases
  26 Scopus citations

• Single-molecule studies on the mechanical interplay between DNA supercoiling and H-NS DNA architectural properties

  Lim, C. J., Kenney, L. J. & Yan, J., 2014, In: Nucleic acids research. 42, 13, p. 8369-8378 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA
  • DNA Packaging
  • Superhelical DNA
  • Nucleoproteins
  • Regulator Genes
  21 Scopus citations

• The horizontally-acquired response regulator SsrB drives a Salmonella lifestyle switch by relieving biofilm silencing

  Desai, S. K., Winardhi, R. S., Periasamy, S., Dykas, M. M., Jie, Y. & Kenney, L. J., Feb 2 2016, In: eLife. 5, FEBRUARY2016, e10747.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Salmonella
  • Biofilms
  • Macrophages
  • Drive
  • Life Style
  28 Scopus citations

• The inner membrane histidine kinase EnvZ senses osmolality via helix-coil transitions in the cytoplasm

  Wang, L. C., Morgan, L. K., Godakumbura, P., Kenney, L. J. & Anand, G. S., May 30 2012, In: EMBO Journal. 31, 11, p. 2648-2659 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Histidine Kinase
  • Osmolar Concentration
  • Osmotic Pressure
  • Membranes
  • Cytoplasm
  71 Scopus citations

• The pearling transition provides evidence of force-driven endosomal tubulation during Salmonella infection

  Gao, Y., Spahn, C., Heilemann, M. & Kenney, L. J., May 1 2018, In: mBio. 9, 3, e01083-18.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Salmonella Infections
  • Salmonella
  • Virulence Factors
  • Kinesin
  • Genomic Islands
  6 Scopus citations
• Comment/debate

  Erratum: The inner membrane histidine kinase EnvZ senses osmolality via helix-coil transitions in the cytoplasm(The EMBO Journal (2012) 31( 2648-2659) 10.1038/emboj.2012.99)

  Wang, L. C., Morgan, L. K., Godakumbura, P., Kenney, L. J. & Anand, G. S., Oct 1 2015, In: EMBO Journal. 34, 19, p. 2481 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
  2 Scopus citations
• Editorial

  Editorial overview: Host-pathogen interactions: bacteria

  Ottemann, K. M. & Kenney, L., Feb 1 2019, In: Current Opinion in Microbiology. 47, p. iii-v

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations
• Review article

  Cytoplasmic sensing by the inner membrane histidine kinase EnvZ

  Foo, Y. H., Gao, Y., Zhang, H. & Kenney, L. J., Sep 1 2015, In: Progress in Biophysics and Molecular Biology. 118, 3, p. 119-129 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Histidine Kinase
  • Osmoregulation
  • Deuterium
  • Hydrogen Bonding
  • Porins
  25 Scopus citations

• H-NS Regulates Gene Expression and Compacts the Nucleoid: Insights from Single-Molecule Experiments

  Winardhi, R. S., Yan, J. & Kenney, L. J., Oct 6 2015, In: Biophysical journal. 109, 7, p. 1321-1329 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Histones
  • Gene Expression
  • Gene Silencing
  • Proteins
  • Single Molecule Imaging
  47 Scopus citations

• Switching Lifestyles Is an in vivo Adaptive Strategy of Bacterial Pathogens

  Desai, S. K. & Kenney, L. J., Dec 11 2019, In: Frontiers in Cellular and Infection Microbiology. 9, 421.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Life Style
  • Salmonella
  • Stochastic Processes
  • Life Cycle Stages
  • Drive
  3 Scopus citations

• The role of acid stress in Salmonella pathogenesis

  Kenney, L., Feb 1 2019, In: Current Opinion in Microbiology. 47, p. 45-51 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Salmonella
  • Acids
  • Vacuoles
  • Virulence
  • Cytoplasm
  15 Scopus citations