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• Article

  A biosafety level-2 dose-dependent lethal mouse model of spotted fever rickettsiosis: Rickettsia parkeri atlantic rainforest strain

  Londoño, A. F., Mendell, N. L., Walker, D. H. & Bouyer, D. H., Jun 2019, In: PLoS neglected tropical diseases. 13, 6, e0007054.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rainforest
  • Spotted Fever Group Rickettsiosis
  • Rickettsia
  • Containment of Biohazards
  • Infection
  2 Scopus citations

• A cluster of cases of rocky mountain spotted fever in an area of Colombia not known to be endemic for this disease

  Londoño, A. F., Arango-Ferreira, C., Acevedo-Gutiérrez, L. Y., Paternina, L. E., Montes, C., Ruiz, I., Labruna, M. B., Díaz, F. J., Walker, D. H. & Rodas, J. D., 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 2, p. 336-342 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Rocky Mountain Spotted Fever
  • Endemic Diseases
  • Colombia
  • Rickettsia rickettsii
  • Molecular Diagnostic Techniques
  2 Scopus citations

• Analysis of health-Care charges in murine typhus: Need for improved clinical recognition and diagnostics for acute disease

  Vohra, R. F., Walker, D. H. & Blanton, L. S., 2018, In: American Journal of Tropical Medicine and Hygiene. 98, 6, p. 1594-1598 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Endemic Flea-Borne Typhus
  • Acute Disease
  • Delivery of Health Care
  • Human Influenza
  • Rickettsia typhi
  5 Scopus citations

• An animal model of a newly emerging human ehrlichiosis

  Saito, T. B., Thirumalapura, N. R., Shelite, T. R., Rockx-Brouwer, D., Popov, V. L. & Walker, D. H., Feb 1 2015, In: Journal of Infectious Diseases. 211, 3, p. 452-461 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • Ehrlichiosis
  • Animal Models
  • Infection
  • Clinical Chemistry
  14 Scopus citations

• A review of the global epidemiology of scrub typhus

  Xu, G., Walker, D. H., Jupiter, D., Melby, P. C. & Arcari, C. M., Nov 3 2017, In: PLoS neglected tropical diseases. 11, 11, e0006062.

  Research output: Contribution to journal › Article › peer-review

  • Scrub Typhus
  • Epidemiology
  • Orientia tsutsugamushi
  • Public Health
  • Neglected Diseases
  75 Scopus citations

• Atg5 supports Rickettsia australis infection in macrophages in vitro and in vivo

  Bechelli, J., Vergara, L., Smalley, C., Buzhdygan, T. P., Bender, S., Zhang, W., Liu, Y., Popov, V. L., Wang, J., Garg, N., Hwang, S., Walker, D. H. & Fang, R., Jan 1 2019, In: Infection and immunity. 87, 1, e00651.

  Research output: Contribution to journal › Article › peer-review

  • Spotted Fever Group Rickettsiosis
  • Macrophages
  • In Vitro Techniques
  • Rickettsia
  • Interleukin-1
  10 Scopus citations

• A Tick Vector Transmission Model of Monocytotropic Ehrlichiosis

  Saito, T. B. & Walker, D. H., Sep 15 2015, In: Journal of Infectious Diseases. 212, 6, p. 968-977 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Ticks
  • Ehrlichia
  • Nymph
  • Larva
  14 Scopus citations

• Burkholderia pseudomallei ΔtonB Δhcp1 live attenuated vaccine strain elicits full protective immunity against aerosolized melioidosis infection

  Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Kilgore, P. B., Ross, B. N., Walker, D. H., Endsley, J. J. & Torresa, A. G., Jan 1 2019, In: mSphere. 4, 1, e00570-18.

  Research output: Contribution to journal › Article › peer-review

  • Melioidosis
  • Burkholderia pseudomallei
  • Attenuated Vaccines
  • Burkholderia mallei
  • Immunity
  11 Scopus citations

• Case report: An unusual cutaneous manifestation in a patient with murine typhus

  Blanton, L. S., Lea, A. S., Kelly, B. C. & Walker, D. H., Dec 2015, In: American Journal of Tropical Medicine and Hygiene. 93, 6, p. 1164-1167 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Endemic Flea-Borne Typhus
  • Skin Manifestations
  • Rickettsia typhi
  • Siphonaptera
  • Mites
  9 Scopus citations

• CD8⁺T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection

  Xu, G., Mendell, N. L., Liang, Y., Shelite, T. R., Goez-Rivillas, Y., Soong, L., Bouyer, D. H. & Walker, D. H., Jul 19 2017, In: PLoS neglected tropical diseases. 11, 7, e0005763.

  Research output: Contribution to journal › Article › peer-review

  • Scrub Typhus
  • Orientia tsutsugamushi
  • T-Lymphocytes
  • Bacterial Load
  • Immunity
  15 Scopus citations

• Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium

  Fang, R., Ismail, N. & Walker, D. H., Jul 2012, In: American Journal of Pathology. 181, 1, p. 185-195 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Natural Killer Cells
  • Endothelium
  • Bacteria
  • Rickettsia
  • Interferons
  21 Scopus citations

• Diagnosing emerging and reemerging infectious diseases: The pivotal role of the pathologist

  Olano, J. P. & Walker, D. H., Jan 1 2011, In: Archives of Pathology and Laboratory Medicine. 135, 1, p. 83-91 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Emerging Communicable Diseases
  • Pathologists
  • Communicable Diseases
  • Molecular Pathology
  • United States Food and Drug Administration
  15 Scopus citations

• Ehrlichia chaffeensis outer membrane protein 1-specific human antibody-mediated immunity is defined by intracellular TRIM21-dependent innate immune activation and extracellular neutralization

  Velayutham, T. S., Kumar, S., Zhang, X., Kose, N., Walker, D. H., Winslow, G., Crowe, J. E. & McBride, J. W., Dec 1 2019, In: Infection and immunity. 87, 12, e00383-19.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ehrlichia chaffeensis
  • Ehrlichia
  • Membrane Proteins
  • Immunity
  • Autophagy
  4 Scopus citations

• Evaluation of Burkholderia mallei ΔtonB Δhcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis

  Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Walker, D. H., Endsley, J. J. & Torres, A. G., Jul 2019, In: PLoS neglected tropical diseases. 13, 7, e0007578.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Burkholderia mallei
  • Glanders
  • Melioidosis
  • Attenuated Vaccines
  • Humoral Immunity
  5 Scopus citations

• Fever and rash after a safari

  Damavandy, A. A., Rojek, N. W., Dugan, E. M., Walker, D. & Norton, S. A., Jan 1 2015, In: Journal of the American Academy of Dermatology. 72, 1, p. e5-e6

  Research output: Contribution to journal › Article › peer-review

• Fever with thrombocytopenia associated with a novel bunyavirus in China

  Yu, X. J., Liang, M. F., Zhang, S. Y., Liu, Y., Li, J. D., Sun, Y. L., Zhang, L., Zhang, Q. F., Popov, V. L., Li, C., Qu, J., Li, Q., Zhang, Y. P., Hai, R., Wu, W., Wang, Q., Zhan, F. X., Wang, X. J., Kan, B., Wang, S. W. & 26 others, Wan, K. L., Jing, H. Q., Lu, J. X., Yin, W. W., Zhou, H., Guan, X. H., Liu, J. F., Bi, Z. Q., Liu, G. H., Ren, J., Wang, H., Zhao, Z., Song, J. D., He, J. R., Wan, T., Zhang, J. S., Fu, X. P., Sun, L. N., Dong, X. P., Feng, Z. J., Yang, W. Z., Hong, T., Zhang, Y., Walker, D. H., Wang, Y. & Li, D. X., Apr 21 2011, In: New England Journal of Medicine. 364, 16, p. 1523-1532 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Orthobunyavirus
  • Thrombocytopenia
  • China
  • Fever
  • Phlebovirus
  767 Scopus citations

• Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium

  Sahni, A., Patel, J., Narra, H. P., Schroeder, C. L. C., Walker, D. H. & Sahni, S. K., Aug 2017, In: PloS one. 12, 8, e0183181.

  Research output: Contribution to journal › Article › peer-review

  • fibroblast growth factor receptor 1
  • Spotted Fever Group Rickettsiosis
  • Endothelial cells
  • Receptor, Fibroblast Growth Factor, Type 1
  • fibroblast growth factor receptors
  10 Scopus citations

• Genotypic characterization of Orientia tsutsugamushi from patients in two geographical locations in Sri Lanka

  Premaratna, R., Blanton, L. S., Samaraweera, D. N., de Silva, G. N. N., Chandrasena, N. T. G. A., Walker, D. H. & de Silva, H. J., Jan 13 2017, In: BMC Infectious Diseases. 17, 1, 67.

  Research output: Contribution to journal › Article › peer-review

  • Orientia tsutsugamushi
  • Sri Lanka
  • Genotype
  • Real-Time Polymerase Chain Reaction
  • Fever
  9 Scopus citations

• Immune Mediators of protective and pathogenic immune responses in patients with mild and fatal human monocytotropic ehrlichiosis

  Ismail, N., Walker, D. H., Ghose, P. & Tang, Y. W., May 21 2012, In: BMC Immunology. 13, 26.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Chemokines
  • Septic Shock
  • Interleukin-1
  • Interleukin-10
  11 Scopus citations

• Immunization with Ehrlichia P28 outer membrane proteins confers protection in a mouse model of ehrlichiosis

  Crocquet-Valdes, P. A., Thirumalapura, N. R., Ismail, N., Yu, X., Saito, T. B., Stevenson, H. L., Pietzsch, C. A., Thomas, S. & Walker, D. H., Dec 2011, In: Clinical and Vaccine Immunology. 18, 12, p. 2018-2025 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • Immunization
  • Ehrlichiosis
  • T-cells
  • Membrane Proteins
  17 Scopus citations

• Mechanisms of immunity to rickettsia and implications for vaccine development

  Walker, D., Jan 1 2017, In: Revista Colombiana de Ciencias Pecuarias. 30, p. 262-263 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Spotted Fever Group Rickettsiosis
  • Rickettsia
  • vaccine development
  • fever
  • immunity

• Molecular and cellular pathobiology of Ehrlichia infection: Targets for new therapeutics and immunomodulation strategies

  McBride, J. W. & Walker, D. H., Jan 2011, In: Expert reviews in molecular medicine. 13, e3.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Immunomodulation
  • Ehrlichia
  • Host-Pathogen Interactions
  • Rickettsiales
  40 Scopus citations

• Murine models of scrub typhus associated with host control of Orientia tsutsugamushi infection

  Mendell, N. L., Bouyer, D. H. & Walker, D. H., Mar 10 2017, In: PLoS neglected tropical diseases. 11, 3, e0005453.

  Research output: Contribution to journal › Article › peer-review

  • Scrub Typhus
  • Orientia tsutsugamushi
  • Infection
  • Trombiculidae
  • Heterologous Immunity
  11 Scopus citations

• Obligate intracellular bacterium Ehrlichia inhibiting mitochondrial activity

  Liu, Y., Zhang, Z., Jiang, Y., Zhang, L., Popov, V. L., Zhang, J., Walker, D. H. & Yu, X. J., Mar 2011, In: Microbes and Infection. 13, 3, p. 232-238 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • Bacteria
  • Mitochondria
  • Phagocytes
  • Ehrlichia chaffeensis
  15 Scopus citations

• Pathogenesis of Rickettsial Diseases: Pathogenic and Immune Mechanisms of an Endotheliotropic Infection

  Sahni, A., Fang, R., Sahni, S. K. & Walker, D. H., 2019, In: Annual Review of Pathology: Mechanisms of Disease. 14, p. 127-152 26 p.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia Infections
  • Actins
  • Endothelial Cells
  • Infection
  • Rickettsia
  13 Scopus citations

• Permissive and protective roles for neutrophils in leishmaniasis

  Carlsen, E. D., Liang, Y., Shelite, T. R., Walker, D. H., Melby, P. C. & Soong, L., Nov 2015, In: Clinical and Experimental Immunology. 182, 2, p. 109-18 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Leishmaniasis
  • Parasites
  • Neutrophils
  • Leishmania
  • Infection
  32 Scopus citations

• Person-to-person transmission of severe fever with thrombocytopenia syndrome virus

  Liu, Y., Li, Q., Hu, W., Wu, J., Weng, Y., Mei, L., Walker, D. H., Ren, J., Wang, Y. & Yu, X. J., Feb 1 2012, In: Vector-Borne and Zoonotic Diseases. 12, 2, p. 156-160 5 p.

  Research output: Contribution to journal › Article › peer-review

  • SFTS phlebovirus
  • Thrombocytopenia
  • Fever
  • Viruses
  • Phlebovirus
  154 Scopus citations

• Reemergence of murine typhus in galveston, texas, usa, 2013

  Blanton, L. S., Vohra, R. F., Bouyer, D. H. & Walker, D. H., 2015, In: Emerging infectious diseases. 21, 3, p. 484-486 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Endemic Flea-Borne Typhus
  • Rickettsia typhi
  • Public Health
  • Physicians
  24 Scopus citations

• Rickettsiae Within the Fleas of Feral Cats in Galveston, Texas

  Blanton, L. S., Vohra, R. F., Fistein, L., Quade, B., Walker, D. H. & Bouyer, D. H., Sep 2019, In: Vector-Borne and Zoonotic Diseases. 19, 9, p. 647-651 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ctenocephalides
  • feral
  • Siphonaptera
  • Rickettsia typhi
  • Endemic Flea-Borne Typhus
  7 Scopus citations

• Rickettsia massiliae and rickettsia conorii israeli spotted fever strain differentially regulate endothelial cell responses

  Bechelli, J., Smalley, C., Milhano, N., Walker, D. H. & Fang, R., Sep 22 2015, In: PloS one. 10, 9, e0138830.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia massiliae
  • Rickettsia conorii
  • Spotted Fever Group Rickettsiosis
  • Endothelial cells
  • Rickettsia
  5 Scopus citations

• Structure-based vaccines provide protection in a mouse model of ehrlichiosis

  Thomas, S., Thirumalapura, N. R., Crocquet-Valdes, P. A., Luxon, B. A. & Walker, D. H., Nov 17 2011, In: PloS one. 6, 11, e27981.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • ehrlichiosis
  • Ehrlichiosis
  • animal models
  • vaccines
  15 Scopus citations

• Susceptibility of Rickettsia rickettsii to Tigecycline in a Cell Culture Assay and Animal Model for Rocky Mountain Spotted Fever

  Blanton, L. S., Wilson, N. M., Quade, B. R. & Walker, D. H., 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 5, p. 1091-1095 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia rickettsii
  • Rocky Mountain Spotted Fever
  • Tigecycline
  • Cell Culture Techniques
  • Animal Models
  2 Scopus citations

• Systemic treatment with cpg-b after sublethal rickettsial infection induces mouse death through indoleamine 2,3-dioxygenase (ido)

  Xin, L., Shelite, T. R., Gong, B., Mendell, N. L., Soong, L., Fang, R. & Walker, D. H., Mar 28 2012, In: PloS one. 7, 3, e34062.

  Research output: Contribution to journal › Article › peer-review

  • indoleamine 2,3-dioxygenase
  • rickettsial diseases
  • T-cells
  • Indoleamine-Pyrrole 2,3,-Dioxygenase
  • Dendritic Cells
  16 Scopus citations

• The role of Rhipicephalus sanguineus sensu lato saliva in the dissemination of Rickettsia conorii in C3H/HeJ mice

  Milhano, N., Saito, T. B., Bechelli, J., Fang, R., Vilhena, M., De Sousa, R. & Walker, D. H., Sep 1 2015, In: Medical and Veterinary Entomology. 29, 3, p. 225-229 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia conorii
  • Rhipicephalus sanguineus
  • tick
  • saliva
  • Ticks
  9 Scopus citations

• Time to Worry about Anthrax Again

  Keim, P. S., Walker, D. H. & Zilinskas, R. A., Mar 14 2017, In: Scientific American. 316, 4, p. 70-75 6 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Vector Tick Transmission Model of Spotted Fever Rickettsiosis

  Saito, T. B., Bechelli, J., Smalley, C., Karim, S. & Walker, D. H., Jan 2019, In: American Journal of Pathology. 189, 1, p. 115-123 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Spotted Fever Group Rickettsiosis
  • Ticks
  • Infection
  • Rickettsia Infections
  • Bacterial Load
  4 Scopus citations

• Whole-genome sequence of rickettsia parkeri strain atlantic rainforest, isolated from a colombian tick

  Londoño, A. F., Mendell, N. L., Valbuena, G. A., Routh, A. L., Wood, T. G., Widen, S. G., Rodas, J. D., Walker, D. H. & Bouyer, D. H., Sep 26 2019, In: Microbiology Resource Announcements. 8, 39, e00684-19.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rainforest
  • Rickettsia
  • Ticks
  • Genome
  • Colombia
• Book

  Tropical Infectious Diseases

  Guerrant, R., Walker, D. H. & Weller, P., 2011, Elsevier Inc.

  Research output: Book/Report › Book

  • Omsk Hemorrhagic Fever
  • Crimean-Congo hemorrhagic fever virus
  • Hepatitis A Vaccines
  • Tick-Borne Encephalitis
  • Mucormycosis
  24 Scopus citations
• Chapter

  Anthrax

  Rao, G. R. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 261-264 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Bartonelloses

  Dehio, C., Maguiña, C. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 265-270 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Chlamydial, Mycoplasmal, Rickettsial, and Ehrlichial Diseases

  Walker, D. H., 2018, Pulmonary Pathology: A Volume in the Series: Foundations in Diagnostic Pathology. Elsevier Inc., p. 315-326 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Distinguishing Tropical Infectious Diseases from Bioterrorism

  Olano, J. P., Peters, C. J. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 879-886 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Human ehrlichioses and rickettsioses in Cameroon

  Ndip, LN., Ndip, R., Walker, D. H. & McBride, J. W., 2012, Current Topics in Tropical Medicine. p. 25-42

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Immunohistology of Infectious Diseases

  Ezyaguirre, E. J., Walker, D. H. & Zaki, S., Jan 1 2011, Diagnostic Immunohistochemistry. Elsevier Inc., p. 58-82 25 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  4 Scopus citations

• Principles of Parasitism: Host-Parasite Interactions

  Olano, J. P., Weller, P. F., Guerrant, R. L. & Walker, D. H., 2011, Tropical Infectious Diseases. Elsevier Inc., p. 1-7 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  1 Scopus citations

• Rickettsia, orientia, ehrlichia, anaplasma and coxiella: Typhus; spotted fevers; scrub typhus; ehrlichioses; Q fever

  Walker, D. & Yu, X. J., Jul 23 2012, Medical Microbiology: Eighteenth Edition. Elsevier Inc., p. 390-399 10 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  1 Scopus citations

• Rocky mountain spotted fever and other rickettsioses

  Walker, D., May 15 2012, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Scrub Typhus

  Kim, I. S. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 334-338 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  10 Scopus citations

• Spotted Fever Group Rickettsioses

  Sexton, D. J. & Walker, D. H., 2011, Tropical Infectious Diseases. Elsevier Inc., p. 323-328 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  2 Scopus citations

• Typhus Group Rickettsioses

  Walker, D. H. & Raoult, D., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 329-333 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  3 Scopus citations