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Article
Activation of Human Peripheral Blood Eosinophils by Cytokines in a Comparative Time-Course Proteomic/Phosphoproteomic Study
Soman, K. V., Stafford, S. J., Pazdrak, K., Wu, Z., Luo, X., White, W. I., Wiktorowicz, J. E., Calhoun, W. J. & Kurosky, A., Aug 4 2017, In: Journal of Proteome Research. 16, 8, p. 2663-2679 17 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Aldose Reductase Inhibition Prevents Allergic Airway Remodeling through PI3K/AKT/GSK3β Pathway in Mice
Yadav, U. C. S., Naura, A. S., Aguilera-Aguirre, L., Boldogh, I., Boulares, H. A., Calhoun, W. J., Ramana, K. V. & Srivastava, S. K., Feb 27 2013, In: PloS one. 8, 2, e57442.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype
Holguin, F., Comhair, S. A. A., Hazen, S. L., Powers, R. W., Khatri, S. S., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Teague, W. G., Chung, K. F., Erzurum, S. C. & Wenzel, S. E., Jan 15 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 2, p. 153-159 7 p.Research output: Contribution to journal › Article › peer-review
97 Scopus citations -
Anticholinergic vs long-acting β-Agonist in combination with inhaled corticosteroids in black adults with asthma: The BELT randomized clinical trial
Wechsler, M. E., Yawn, B. P., Fuhlbrigge, A. L., Pace, W. D., Pencina, M. J., Doros, G., Kazani, S., Raby, B. A., Lanzillotti, J., Madison, S., Israel, E., Ansari, A., Raum, D., Marthur, M., Avila, P., Bailey, J. E., Calhoun, W. J., Chang, K. L., Coto, M., Davis, C. & 8 others, , Oct 27 2015, In: JAMA - Journal of the American Medical Association. 314, 16, p. 1720-1730 11 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
Assessing and Evaluating Multidisciplinary Translational Teams: A Mixed Methods Approach
Wooten, K. C., Rose, R. M., Ostir, G. V., Calhoun, W. J., Ameredes, B. T. & Brasier, A. R., 2014, In: Evaluation and the Health Professions. 37, 1, p. 33-49 17 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study
Silkoff, P. E., Strambu, I., Laviolette, M., Singh, D., FitzGerald, J. M., Lam, S., Kelsen, S., Eich, A., Ludwig-Sengpiel, A., hupp, G. C., Backer, V., Porsbjerg, C., Girodet, P. O., Berger, P., Leigh, R., Kline, J. N., Dransfield, M., Calhoun, W., Hussaini, A., Khatri, S. & 8 others, , Nov 17 2015, In: Respiratory Research. 16, 1, 142.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
Asthma exacerbations and lung function in patients with severe or difficult-to-treat asthma
Calhoun, W., Haselkorn, T., Miller, D. P. & Omachi, T. A., Oct 1 2015, In: Journal of Allergy and Clinical Immunology. 136, 4, p. 1125-1127e4Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Asthma is more severe in older adults
Zein, J. G., Dweik, R. A., Comhair, S. A., Bleecker, E. R., Moore, W. C., Peters, S. P., Busse, W. W., Jarjour, N. N., Calhoun, W. J., Castro, M., Chung, K. F., Fitzpatrick, A., Israel, E., Teague, W. G., Wenzel, S. E., Love, T. E., Gaston, B. M. & Erzurum, S. C., Jul 22 2015, In: PloS one. 10, 7, e0133490.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Characteristics of perimenstrual asthma and its relation to asthma severity and control: Data from the Severe Asthma Research Program
Rao, C. K., Moore, C. G., Bleecker, E., Busse, W. W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S. C., Israel, E., Curran-Everett, D. & Wenzel, S. E., Apr 2013, In: Chest. 143, 4, p. 984-992 9 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
Children and Adults With Frequent Hospitalizations for Asthma Exacerbation, 2012-2013: A Multicenter Observational Study
Multicenter Airway Research Collaboration-37 Investigators, Sep 1 2015, In: Journal of Allergy and Clinical Immunology: In Practice. 3, 5, p. 751-758.e1Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Clinical burden and predictors of asthma exacerbations in patients on guideline-based steps 4-6 asthma therapy in the TENOR cohort
Calhoun, W. J., Haselkorn, T., Mink, D. R., Miller, D. P., Dorenbaum, A. & Zeiger, R. S., Mar 2014, In: Journal of Allergy and Clinical Immunology: In Practice. 2, 2, p. 193-200.e3Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Clinical implications of having reduced mid forced expiratory flow rates (FEF25-75), independently of FEV1, in adult patients with asthma
Riley, C. M., Wenzel, S. E., Castro, M., Erzurum, S. C., Chung, K. F., Fitzpatrick, A. M., Gaston, B., Israel, E., Moore, W. C., Bleecker, E. R., Calhoun, W. J., Jarjour, N. N., Busse, W. W., Peters, S. P., Teague, W. G., Sorkness, R. & Holguin, F., Dec 2015, In: PloS one. 10, 12, e0145476.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: The BASALT randomized controlled trial
Calhoun, W. J., Ameredes, B. T., King, T. S., Icitovic, N., Bleecker, E. R., Castro, M., Cherniack, R. M., Chinchilli, V. M., Craig, T., Denlinger, L., DiMango, E. A., Engle, L. L., Fahy, J. V., Grant, J. A., Israel, E., Jarjour, N., Kazani, S. D., Kraft, M., Kunselman, S. J., Lazarus, S. C. & 15 others, , Sep 5 2012, In: JAMA - Journal of the American Medical Association. 308, 10, p. 987-997 11 p.Research output: Contribution to journal › Article › peer-review
124 Scopus citations -
Cytokine-induced glucocorticoid resistance from eosinophil activation: Protein phosphatase 5 modulation of glucocorticoid receptor phosphorylation and signaling
Pazdrak, K., Straub, C., Maroto, R., Stafford, S., White, W. I., Calhoun, W. J. & Kurosky, A., Nov 15 2016, In: Journal of Immunology. 197, 10, p. 3782-3791 10 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: A randomized clinical trial
Smith, L. J., Kalhan, R., Wise, R. A., Sugar, E. A., Lima, J. J., Irvin, C. G., Dozor, A. J., Holbrook, J. T., Hanania, N., Sockrider, M., Bertrand, L., Atik, M. A., Lopez, B. A., Reibman, J., DiMango, E., Rogers, L., Carapetyan, K., Rivera, K., Bryce-Robinson, N., Scheuerman, M. & 180 others, , May 26 2015, In: JAMA - Journal of the American Medical Association. 313, 20, p. 2033-2043 11 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Effects of acute ethanol exposure on cytokine production by primary airway smooth muscle cells
Kaphalia, L., Kalita, M., Kaphalia, B. S. & Calhoun, W. J., Feb 1 2016, In: Toxicology and Applied Pharmacology. 292, p. 85-93 9 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Ethanol metabolism, oxidative stress, and endoplasmic reticulum stress responses in the lungs of hepatic alcohol dehydrogenase deficient deer mice after chronic ethanol feeding
Kaphalia, L., Boroumand, N., Hyunsu, J., Kaphalia, B. S. & Calhoun, W. J., Jun 1 2014, In: Toxicology and Applied Pharmacology. 277, 2, p. 109-117 9 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Evolution of Multidisciplinary Translational Teams (MTTs): Insights for Accelerating Translational Innovations
Wooten, K. C., Calhoun, W. J., Bhavnani, S., Rose, R. M., Ameredes, B. & Brasier, A. R., Oct 2015, In: Clinical and translational science. 8, 5, p. 542-552 11 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients
Li, X., Hawkins, G. A., Ampleford, E. J., Moore, W. C., Li, H., Hastie, A. T., Howard, T. D., Boushey, H. A., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Israel, E., Lemanske, R. F., Szefler, S. J., Wasserman, S. I., Wenzel, S. E., Peters, S. P., Meyers, D. A. & Bleecker, E. R., Aug 2013, In: Journal of Allergy and Clinical Immunology. 132, 2, p. 313-320.e15Research output: Contribution to journal › Article › peer-review
67 Scopus citations -
HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma
Zein, J., Gaston, B., Bazeley, P., DeBoer, M. D., Igo, R. P., Bleecker, E. R., Meyers, D., Comhair, S., Marozkina, N. V., Cotton, C., Patel, M., Alyamani, M., Xu, W., Busse, W. W., Calhoun, W. J., Ortega, V., Hawkins, G. A., Castro, M., Chung, K. F., Fahy, J. V. & 12 others, , Jan 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2187-2193 7 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients
Silkoff, P. E., Laviolette, M., Singh, D., FitzGerald, J. M., Kelsen, S., Backer, V., Porsbjerg, C. M., Girodet, P. O., Berger, P., Kline, J. N., Chupp, G., Susulic, V. S., Barnathan, E. S., Baribaud, F., Loza, M. J., Strambu, I., Lam, S., Eich, A., Ludwig-Sengpiel, A., Leigh, R. & 4 others, , Sep 2017, In: Journal of Allergy and Clinical Immunology. 140, 3, p. 710-719 10 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Impact of Age and Sex on Outcomes and Hospital Cost of Acute Asthma in the United States, 2011-2012
Zein, J. G., Udeh, B. L., Teague, W. G., Koroukian, S. M., Schlitz, N. K., Bleecker, E. R., Busse, W. B., Calhoun, W. J., Castro, M., Comhair, S. A., Fitzpatrick, A. M., Israel, E., Wenzel, S. E., Holguin, F., Gaston, B. M. & Erzurum, S. C., Jun 2016, In: PloS one. 11, 6, e0157301.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Improving Quality of Acute Asthma Care in US Hospitals: Changes Between 1999-2000 and 2012-2013
Hasegawa, K., Tsugawa, Y., Clark, S., Eastin, C. D., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Ahn, J., Aurora, T., Brenner, B., Brown, M. A., Calhoun, W., Gough, J. E., Gharib, A., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S. & 11 others, , Jul 1 2016, In: Chest. 150, 1, p. 112-122 11 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study
The ADEPT Investigators, 2016, In: Respiratory Research. 17, 1, p. 1-12 12 p., 43.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy
Denlinger, L. C., Manthei, D. M., Seibold, M. A., Ahn, K., Bleecker, E., Boushey, H. A., Calhoun, W. J., Castro, M., Chinchili, V. M., Fahy, J. V., Hawkins, G. A., Icitovic, N., Israel, E., Jarjour, N. N., King, T., Kraft, M., Lazarus, S. C., Lehman, E., Martin, R. J., Meyers, D. A. & 8 others, , Jan 1 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 1, p. 28-33 6 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Post-transplant native pneumonectomy for interstitial fibrosis and small cell lung cancer
Li, R. T., Zahedi, S., Trieu, J., Lea, A. S., Calhoun, W. J., Duarte, A. G., Zhao, J. & Okereke, I. C., Dec 1 2017, In: Journal of Thoracic Disease. 9, 12, p. E1096-E1099Research output: Contribution to journal › Article › peer-review
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Predictors of response to tiotropium versus salmeterol in asthmatic adults
Peters, S. P., Bleecker, E. R., Kunselman, S. J., Icitovic, N., Moore, W. C., Pascual, R., Ameredes, B. T., Boushey, H. A., Calhoun, W. J., Castro, M., Cherniack, R. M., Craig, T., Denlinger, L. C., Engle, L. L., Dimango, E. A., Israel, E., Kraft, M., Lazarus, S. C., Lemanske, R. F., Lugogo, N. & 10 others, , Nov 2013, In: Journal of Allergy and Clinical Immunology. 132, 5, p. 1068-1074.e1Research output: Contribution to journal › Article › peer-review
86 Scopus citations -
Race is associated with differences in airway inflammation in patients with asthma
Nyenhuis, S. M., Krishnan, J. A., Berry, A., Calhoun, W. J., Chinchilli, V. M., Engle, L., Grossman, N., Holguin, F., Israel, E., Kittles, R. A., Kraft, M., Lazarus, S. C., Lehman, E. B., Mauger, D. T., Moy, J. N., Peters, S. P., Phipatanakul, W., Smith, L. J., Sumino, K., Szefler, S. J. & 4 others, , Jul 2017, In: Journal of Allergy and Clinical Immunology. 140, 1, p. 257-265.e11Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
Sex differences in hospital length of stay in children and adults hospitalized for asthma exacerbation
Hasegawa, K., Calhoun, W. J., Pei, Y. V., Chasm, R. M., Youngquist, S. T., Bittner, J. C. & Camargo, C. A., Dec 1 2015, In: Annals of Allergy, Asthma and Immunology. 115, 6, p. 533-535.e1Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Sleep quality and asthma control and quality of life in non-severe and severe asthma
Luyster, F. S., Teodorescu, M., Bleecker, E., Busse, W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S., Israel, E., Strollo, P. J. & Wenzel, S. E., Dec 2012, In: Sleep and Breathing. 16, 4, p. 1129-1137 9 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
Strategies for molecular classification of asthma using bipartite network analysis of cytokine expression
Pillai, R. R., Divekar, R., Brasier, A., Bhavnani, S. & Calhoun, W. J., Oct 2012, In: Current Allergy and Asthma Reports. 12, 5, p. 388-395 8 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Symptom-based controller therapy: A new paradigm for asthma management
Divekar, R., Ameredes, B. T. & Calhoun, W. J., Oct 2013, In: Current Allergy and Asthma Reports. 13, 5, p. 427-433 7 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
The CTSA as an Exemplar Framework for Developing Multidisciplinary Translational Teams
Calhoun, W. J., Wooten, K., Bhavnani, S., Anderson, K. E., Freeman, J. & Brasier, A. R., Feb 2013, In: Clinical and translational science. 6, 1, p. 60-71 12 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma
Chu, D. K., Al-Garawi, A., Llop-Guevara, A., Pillai, R. A., Radford, K., Shen, P., Walker, T. D., Goncharova, S., Calhoun, W. J., Nair, P. & Jordana, M., Apr 12 2015, In: Allergy, Asthma and Clinical Immunology. 11, 1, 14.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
The role of computed tomography in chronic obstructive pulmonary diseases
Sze, T. F. C., Ditzler, M. G., Walser, E. M. & Calhoun, W. J., 2015, In: Journal of Allergy and Clinical Immunology: In Practice. 3, 4, p. 594-596 3 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Underuse of guideline-recommended long-term asthma management in children hospitalized to the intensive care unit: A multicenter observational study
Hasegawa, K., Ahn, J., Brown, M. A., Press, V. G., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Aurora, T., Brenner, B., Calhoun, W., Gough, J. E., Gutta, R. C., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S., Nowak, R., Pei, V. & 9 others, , Jul 1 2015, In: Annals of Allergy, Asthma and Immunology. 115, 1, p. 10-16.e1Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data
Wu, W., Bleecker, E., Moore, W., Busse, W. W., Castro, M., Chung, K. F., Calhoun, W. J., Erzurum, S., Gaston, B., Israel, E., Curran-Everett, D. & Wenzel, S. E., May 2014, In: Journal of Allergy and Clinical Immunology. 133, 5, p. 1280-1288 9 p.Research output: Contribution to journal › Article › peer-review
149 Scopus citations -
Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study
For the ADEPT (Airways Disease Endotyping for Personalized Therapeutics) & U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) investigators, Dec 15 2016, In: Respiratory Research. 17, 1, 165.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Chapter
Conclusions and future directions
Calhoun, W. J. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Conclusions and future directions
Calhoun, W. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Heterogeneity of asthma in society
Divekar, R. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Heterogeneity of asthma in society
Divekar, R. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Heterogeneity of response to therapy
Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Heterogeneity of response to therapy
Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Introduction to asthma and phenotyping
Pillai, R. A. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Introduction to asthma and phenotyping
Pillai, R. A. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
5 Scopus citations -
Comment/debate
Physician-, biomarker-, and symptombased djustment of inhaled corticosteroids for asthma had similar effects
Calhoun, W. J., Jan 24 2013, In: Annals of internal medicine. 158, 2, p. JC6Research output: Contribution to journal › Comment/debate › peer-review
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Editorial
The spectrum of asthma: an introduction.
Calhoun, W. J., 2014, In: Advances in experimental medicine and biology. 795, p. 1-4 4 p.Research output: Contribution to journal › Editorial › peer-review
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Letter
30-Day Readmissions in Hospitalized Adults With Asthma Exacerbations: Insights From the Nationwide Readmission Database
Veeranki, S. P., Sharma, K., Ohabughiro, M. U., Mehta, H. B., Adhikari, D., Kuo, Y. F. & Calhoun, W. J., Nov 1 2016, In: Chest. 150, 5, p. 1162-1165 4 p.Research output: Contribution to journal › Letter › peer-review
6 Scopus citations -
Strategies for Tailoring Asthma Treatment in Adults-Reply
Calhoun, W. J., Boushey, H. A. & Ameredes, B. T., Jan 9 2013, In: JAMA - Journal of the American Medical Association. 309, 2, p. 136-137 2 p.Research output: Contribution to journal › Letter › peer-review