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  2′-O methylation of internal adenosine by flavivirus NS5 methyltransferase

  Dong, H., Chang, D. C., Hua, M. H. C., Lim, S. P., Chionh, Y. H., Hia, F., Lee, Y. H., Kukkaro, P., Lok, S. M., Dedon, P. C. & Shi, P. Y., Apr 2012, In: PLoS pathogens. 8, 4, e1002642.

  Research output: Contribution to journal › Article › peer-review

  • Flavivirus
  • Methyltransferases
  • Adenosine
  • Methylation
  • 2'-O-methyladenosine
  85 Scopus citations

• A cDNA Clone-Launched Platform for High-Yield Production of Inactivated Zika Vaccine

  Yang, Y., Shan, C., Zou, J., Muruato, A. E., Bruno, D. N., de Almeida Medeiros Daniele, B., Vasconcelos, P. F. C., Rossi, S. L., Weaver, S. C., Xie, X. & Shi, P. Y., Mar 1 2017, In: EBioMedicine. 17, p. 145-156 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Inactivated Vaccines
  • Viruses
  • Zika Virus
  • Complementary DNA
  • Clone Cells
  28 Scopus citations

• A chimeric dengue virus vaccine using japanese encephalitis virus vaccine strain SA14-14-2 as backbone is immunogenic and protective against either parental virus in mice and nonhuman primates

  Li, X. F., Deng, Y. Q., Yang, H. Q., Zhao, H., Jiang, T., Yu, X. D., Li, S. H., Ye, Q., Zhu, S. Y., Wang, H. J., Zhang, Y., Ma, J., Yu, Y. X., Liu, Z. Y., Li, Y. H., Qin, E. D., Shi, P. Y. & Qin, C. F., Dec 2013, In: Journal of virology. 87, 24, p. 13694-13705 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Vaccines
  • Japanese encephalitis virus
  • Japanese Encephalitis Virus
  • Dengue virus
  • Dengue Virus
  43 Scopus citations

• A cocrystal structure of dengue capsid protein in complex of inhibitor

  Xia, H., Xie, X., Zou, J., Noble, C. G., Russell, W. K., Holthauzen, L. M. F., Choi, K. H., White, M. A. & Shi, P. Y., Jul 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 30, p. 17992-18001 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Dengue
  • Capsid Proteins
  • Capsid
  • Serogroup

• A crystal structure of the dengue virus non-structural protein 5 (NS5) polymerase delineates interdomain amino acid residues that enhance its thermostability and de novo initiation activities

  Lim, S. P., Koh, J. H. K., Seh, C. C., Liew, C. W., Davidson, A. D., Chua, L. S., Chandrasekaran, R., Cornvik, T. C., Shi, P. Y. & Lescar, J., Oct 25 2013, In: Journal of Biological Chemistry. 288, 43, p. 31105-31114 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Viral Structural Proteins
  • RNA Replicase
  • Crystal structure
  • Dengue Virus
  • Viruses
  55 Scopus citations

• A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication

  Zhao, Y., Soh, T. S., Zheng, J., Chan, K. W. K., Phoo, W. W., Lee, C. C., Tay, M. Y. F., Swaminathan, K., Cornvik, T. C., Lim, S. P., Shi, P. Y., Lescar, J., Vasudevan, S. G. & Luo, D., Mar 1 2015, In: PLoS pathogens. 11, 3, p. 1-27 27 p., e1004682.

  Research output: Contribution to journal › Article › peer-review

  • dengue virus NS5 protein
  • RNA Replicase
  • Virus Replication
  • Flavivirus
  • Methyltransferases
  107 Scopus citations

• A Cyclic Phosphoramidate Prodrug of 2=-Deoxy-2=-Fluoro-2=-C-Methylguanosine for the Treatment of Dengue Virus Infection

  Karuna, R., Yokokawa, F., Wang, K., Zhang, J., Xu, H., Wang, G., Ding, M., Chan, W. L., Ghafar, N. A., Leonardi, A., Seh, C. C., Seah, P. G., Liu, W., Srinivasa, R. P. S., Lim, S. P., Lakshminarayana, S. B., Growcott, E., Babu, S., Fenaux, M., Zhong, W. & 4 others, Gu, F., Shi, P. Y., Blasco, F. & Chen, Y. L., Dec 2020, In: Antimicrobial agents and chemotherapy. 64, 12, e00654-20.

  Research output: Contribution to journal › Article › peer-review

• Aedes mosquitoes acquire and transmit Zika virus by breeding in contaminated aquatic environments

  Du, S., Liu, Y., Liu, J., Zhao, J., Champagne, C., Tong, L., Zhang, R., Zhang, F., Qin, C. F., Ma, P., Chen, C. H., Liang, G., Liu, Q., Shi, P. Y., Cazelles, B., Wang, P., Tian, H. & Cheng, G., Dec 1 2019, In: Nature communications. 10, 1, 1324.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus
  • Aedes
  • viruses
  • Viruses
  • Breeding
  12 Scopus citations

• A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation

  Muruato, A. E., Fontes-Garfias, C. R., Ren, P., Garcia-Blanco, M. A., Menachery, V. D., Xie, X. & Shi, P. Y., Dec 1 2020, In: Nature communications. 11, 1, 4059.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • vaccines
  • SARS Virus
  • antibodies
  • Assays
  • Neutralizing Antibodies
  22 Scopus citations

• A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models

  Shan, C., Muruato, A. E., Nunes, B. T. D., Luo, H., Xie, X., Medeiros, D. B. A., Wakamiya, M., Tesh, R. B., Barrett, A. D., Wang, T., Weaver, S. C., Vasconcelos, P. F. C., Rossi, S. L. & Shi, P. Y., Jun 1 2017, In: Nature Medicine. 23, 6, p. 763-767 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Viruses
  • Immunity
  • Vaccines
  • Epidemics
  159 Scopus citations

• A multidimensional platform for the purification of non-coding RNA species

  Chionh, Y. H., Ho, C. H., Pruksakorn, D., Ramesh Babu, I., Ng, C. S., Hia, F., McBee, M. E., Su, D., Pang, Y. L. J., Gu, C., Dong, H., Prestwich, E. G., Shi, P. Y., Preiser, P. R., Alonso, S. & Dedon, P. C., Sep 2013, In: Nucleic acids research. 41, 17, p. e168

  Research output: Contribution to journal › Article › peer-review

  • Untranslated RNA
  • Ribonucleosides
  • Viral Genome
  • RNA
  • Plasmodium
  28 Scopus citations

• A Multiplex Microsphere Immunoassay for Zika Virus Diagnosis

  Wong, S. J., Furuya, A., Zou, J., Xie, X., Dupuis, A. P., Kramer, L. D. & Shi, P. Y., Feb 1 2017, In: EBioMedicine. 16, p. 136-140 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Microspheres
  • Viruses
  • Immunoassay
  • Zika Virus Infection
  58 Scopus citations

• A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19

  Xie, X., Muruato, A. E., Zhang, X., Lokugamage, K. G., Fontes-Garfias, C. R., Zou, J., Liu, J., Ren, P., Balakrishnan, M., Cihlar, T., Tseng, C. T. K., Makino, S., Menachery, V. D., Bilello, J. P. & Shi, P. Y., Dec 1 2020, In: Nature communications. 11, 1, 5214.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus
  • Coronavirus
  • drugs
  • Screening
  • screening
  6 Scopus citations

• An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses

  Li, G., Adam, A., Luo, H., Shan, C., Cao, Z., Fontes-Garfias, C. R., Sarathy, V. V., Teleki, C., Winkelmann, E. R., Liang, Y., Sun, J., Bourne, N., Barrett, A. D. T., Shi, P. Y. & Wang, T., Dec 1 2019, In: npj Vaccines. 4, 1, 48.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus
  • Mutant Proteins
  • Antiviral Agents
  • Attenuated Vaccines
  • Flavivirus
  4 Scopus citations

• An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

  Xia, H., Luo, H., Shan, C., Muruato, A. E., Nunes, B. T. D., Medeiros, D. B. A., Zou, J., Xie, X., Giraldo, M. I., Vasconcelos, P. F. C., Weaver, S. C., Wang, T., Rajsbaum, R. & Shi, P. Y., Dec 1 2018, In: Nature communications. 9, 1, 414.

  Research output: Contribution to journal › Article › peer-review

  • interferon
  • Zika Virus
  • viruses
  • Viruses
  • mutations
  95 Scopus citations

• An Infectious cDNA Clone of SARS-CoV-2

  Xie, X., Muruato, A., Lokugamage, K. G., Narayanan, K., Zhang, X., Zou, J., Liu, J., Schindewolf, C., Bopp, N. E., Aguilar, P. V., Plante, K. S., Weaver, S. C., Makino, S., LeDuc, J. W., Menachery, V. D. & Shi, P. Y., May 13 2020, In: Cell Host and Microbe. 27, 5, p. 841-848.e3

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Clone Cells
  • SARS Virus
  • DNA
  62 Scopus citations

• Anti-Zika virus RNAi in neural progenitor cells

  Xie, X. & Shi, P. Y., Apr 1 2019, In: Cell Research. 29, 4, p. 261-262 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Scopus citations

• A Rapid Zika Diagnostic Assay to Measure Neutralizing Antibodies in Patients

  Shan, C., Xie, X., Ren, P., Loeffelholz, M. J., Yang, Y., Furuya, A., Dupuis, A. P., Kramer, L. D., Wong, S. J. & Shi, P. Y., Mar 1 2017, In: EBioMedicine. 17, p. 157-162 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Viruses
  • Assays
  • Neutralizing Antibodies
  • Zika Virus Infection
  • Neutralization Tests
  45 Scopus citations

• A replication-defective Japanese encephalitis virus (JEV) vaccine candidate with NS1 deletion confers dual protection against JEV and West Nile virus in mice

  Li, N., Zhang, Z. R., Zhang, Y. N., Liu, J., Deng, C. L., Shi, P. Y., Yuan, Z. M., Ye, H. Q. & Zhang, B., Dec 1 2020, In: npj Vaccines. 5, 1, 73.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Japanese Encephalitis Virus
  • West Nile virus
  • Vaccines
  • Flavivirus
  • West Nile Virus Vaccines

• A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

  Shan, C., Muruato, A. E., Jagger, B. W., Richner, J., Nunes, B. T. D., Medeiros, D. B. A., Xie, X., Nunes, J. G. C., Morabito, K. M., Kong, W. P., Pierson, T. C., Barrett, A. D., Weaver, S. C., Rossi, S. L., Vasconcelos, P. F. C., Graham, B. S., Diamond, M. S. & Shi, P. Y., Dec 1 2017, In: Nature communications. 8, 1, 676.

  Research output: Contribution to journal › Article › peer-review

  • vaccines
  • testes
  • pregnancy
  • Zika Virus
  • Attenuated Vaccines
  80 Scopus citations

• A Single-Dose Live-Attenuated Zika Virus Vaccine with Controlled Infection Rounds that Protects against Vertical Transmission

  Xie, X., Kum, D. B., Xia, H., Luo, H., Shan, C., Zou, J., Muruato, A. E., Medeiros, D. B. A., Nunes, B. T. D., Dallmeier, K., Rossi, S. L., Weaver, S. C., Neyts, J., Wang, T., Vasconcelos, P. F. C. & Shi, P. Y., Oct 10 2018, In: Cell Host and Microbe. 24, 4, p. 487-499.e5

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Vaccines
  • Infection
  • Attenuated Vaccines
  • Capsid Proteins
  23 Scopus citations

• A single-dose plasmid-launched live-attenuated Zika vaccine induces protective immunity

  Zou, J., Xie, X., Luo, H., Shan, C., Muruato, A. E., Weaver, S. C., Wang, T. & Shi, P. Y., Oct 2018, In: EBioMedicine. 36, p. 92-102 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Attenuated Vaccines
  • Immunity
  • Plasmids
  • Vaccines
  • DNA
  21 Scopus citations

• A single mutation in the prM protein of Zika virus contributes to fetal microcephaly

  Yuan, L., Huang, X. Y., Liu, Z. Y., Zhang, F., Zhu, X. L., Yu, J. Y., Ji, X., Xu, Y. P., Li, G., Li, C., Wang, H. J., Deng, Y. Q., Wu, M., Cheng, M. L., Ye, Q., Xie, D. Y., Li, X. F., Wang, X., Shi, W., Hu, B. & 3 others, Shi, P. Y., Xu, Z. & Qin, C. F., Nov 17 2017, In: Science. 358, 6365, p. 933-936 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Microcephaly
  • Mutation
  • Epidemics
  • Polynesia
  215 Scopus citations

• A survey of core replacements in indole-based HIV-1 attachment inhibitors

  Wang, T., Wallace, O. B., Zhang, Z., Fang, H., Yang, Z., Robinson, B. A., Spicer, T. P., Gong, Y. F., Blair, W. S., Shi, P. Y., Lin, P. F., Deshpande, M., Meanwell, N. A. & Kadow, J. F., Jun 1 2019, In: Bioorganic and Medicinal Chemistry Letters. 29, 11, p. 1423-1429 7 p.

  Research output: Contribution to journal › Article › peer-review

  • indole
  • HIV-1
  • Antiviral Agents
  • quinoline
  • naphthalene
  6 Scopus citations

• Axl promotes zika virus entry and modulates the antiviral state of human sertoli cells

  Strange, D. P., Jiyarom, B., Zarandi, N. P., Xie, X., Baker, C., Sadri-Ardekani, H., Shi, P. Y. & Verma, S., Jul 1 2019, In: mBio. 10, 4, e01372-19.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus
  • Virus Internalization
  • Sertoli Cells
  • Antiviral Agents
  • Zika Virus Infection
  20 Scopus citations

• A Zika virus envelope mutation preceding the 2015 epidemic enhances virulence and fitness for transmission

  Shan, C., Xia, H., Haller, S. L., Azar, S. R., Liu, Y., Liu, J., Muruato, A. E., Chen, R., Rossi, S. L., Wakamiya, M., Vasilakis, N., Pei, R., Fontes-Garfias, C. R., Singh, S. K., Xie, X., Weaver, S. C. & Shi, P. Y., Aug 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 33, p. 20190-20197 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Viremia
  • Virulence
  • Epidemics
  • Mutation
  8 Scopus citations

• A Zika virus vaccine expressing premembrane-envelope-NS1 polyprotein

  Li, A., Yu, J., Lu, M., Ma, Y., Attia, Z., Shan, C., Xue, M., Liang, X., Craig, K., Makadiya, N., He, J. J., Jennings, R., Shi, P. Y., Peeples, M. E., Liu, S. L., Boyaka, P. N. & Li, J., Dec 1 2018, In: Nature communications. 9, 1, 3067.

  Research output: Contribution to journal › Article › peer-review

  • vaccines
  • Zika Virus
  • Polyproteins
  • viruses
  • Viruses
  27 Scopus citations

• Characterization of a candidate tetravalent vaccine based on 2’-O-methyltransferase mutants

  Züst, R., Li, S. H., Xie, X., Velumani, S., Chng, M., Toh, Y. X., Zou, J., Dong, H., Shan, C., Pang, J., Qin, C. F., Newell, E. W., Shi, P. Y. & Fink, K., Jan 2018, In: PloS one. 13, 1, e0189262.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Dengue Virus
  • Viruses
  • Methyltransferases
  • methyltransferases
  4 Scopus citations

• Characterization of Dengue virus NS4A and NS4B protein interaction

  Zou, J., Xie, X., Wang, Q. Y., Dong, H., Lee, M. Y., Kang, C., Yuan, Z. & Shi, P. Y., 2015, In: Journal of virology. 89, 7, p. 3455-3470 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus NS4A protein
  • Dengue virus NS4B protein
  • Dengue virus
  • virus replication
  • Amino Acids
  70 Scopus citations

• Combined treatment of adenosine nucleoside inhibitor NITD008 and histone deacetylase inhibitor vorinostat represents an immunotherapy strategy to ameliorate West Nile virus infection

  Nelson, J., Roe, K., Orillo, B., Shi, P. Y. & Verma, S., Oct 1 2015, In: Antiviral research. 122, p. 39-45 7 p., 3668.

  Research output: Contribution to journal › Article › peer-review

  • NITD008
  • West Nile Fever
  • Vorinostat
  • Histone Deacetylase Inhibitors
  • West Nile virus
  17 Scopus citations

• Conformational flexibility of the dengue virus RNA-Dependent RNA polymerase revealed by a complex with an inhibitor

  Noble, C. G., Lim, S. P., Chen, Y. L., Liew, C. W., Yap, L., Lescar, J. & Shi, P. Y., May 2013, In: Journal of virology. 87, 9, p. 5291-5295 5 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Replicase
  • Dengue virus
  • RNA-directed RNA polymerase
  • Dengue Virus
  • Serogroup
  70 Scopus citations

• Construction of stable reporter flaviviruses and their applications

  Baker, C. & Shi, P. Y., Oct 2020, In: Viruses. 12, 10, 1082.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Flavivirus
  • Epidemics
  • Antiviral Agents
  • Vaccines
  • Viruses

• COVID-19 vaccine BNT162b1 elicits human antibody and T_H1 T cell responses

  Sahin, U., Muik, A., Derhovanessian, E., Vogler, I., Kranz, L. M., Vormehr, M., Baum, A., Pascal, K., Quandt, J., Maurus, D., Brachtendorf, S., Lörks, V., Sikorski, J., Hilker, R., Becker, D., Eller, A. K., Grützner, J., Boesler, C., Rosenbaum, C., Kühnle, M. C. & 22 others, Luxemburger, U., Kemmer-Brück, A., Langer, D., Bexon, M., Bolte, S., Karikó, K., Palanche, T., Fischer, B., Schultz, A., Shi, P. Y., Fontes-Garfias, C., Perez, J. L., Swanson, K. A., Loschko, J., Scully, I. L., Cutler, M., Kalina, W., Kyratsous, C. A., Cooper, D., Dormitzer, P. R., Jansen, K. U. & Türeci, Ö., Oct 22 2020, In: Nature. 586, 7830, p. 594-599 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Coronavirus
  • Th1 Cells
  • Vaccines
  • Severe Acute Respiratory Syndrome
  • Antibodies
  50 Scopus citations

• Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: Implication for a trans mechanism of VPg uridylylation

  Chen, C., Wang, Y., Shan, C., Sun, Y., Xu, P., Zhou, H., Yang, C., Shi, P. Y., Rao, Z., Zhang, B. & Lou, Z., May 1 2013, In: Journal of virology. 87, 10, p. 5755-5768 14 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Replicase
  • RNA-directed RNA polymerase
  • Enterovirus
  • crystal structure
  • Picornaviridae
  45 Scopus citations

• Dengue NS2A Protein Orchestrates Virus Assembly

  Xie, X., Zou, J., Zhang, X., Zhou, Y., Routh, A. L., Kang, C., Popov, V. L., Chen, X., Wang, Q. Y., Dong, H. & Shi, P. Y., Nov 13 2019, In: Cell Host and Microbe. 26, 5, p. 606-622.e8

  Research output: Contribution to journal › Article › peer-review

  • Virus Assembly
  • Dengue
  • Virion
  • Polyproteins
  • Nucleocapsid
  17 Scopus citations

• Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission

  Pompon, J., Manuel, M., Ng, G. K., Wong, B., Shan, C., Manokaran, G., Soto-Acosta, R., Bradrick, S. S., Ooi, E. E., Missé, D., Shi, P. Y. & Garcia-Blanco, M. A., Jul 2017, In: PLoS pathogens. 13, 7, e1006535.

  Research output: Contribution to journal › Article › peer-review

  • Dengue
  • Culicidae
  • Salivary Glands
  • Immunity
  • RNA
  47 Scopus citations

• Design, Synthesis, and Biological Evaluation of Substituted 4,6-Dihydrospiro[[1,2,3]triazolo[4,5- b]pyridine-7,3′-indoline]-2′,5(3 H)-dione Analogues as Potent NS4B Inhibitors for the Treatment of Dengue Virus Infection

  Xu, J., Xie, X., Ye, N., Zou, J., Chen, H., White, M. A., Shi, P. Y. & Zhou, J., Sep 12 2019, In: Journal of medicinal chemistry. 62, 17, p. 7941-7960 20 p.

  Research output: Contribution to journal › Article › peer-review

  • indoline-2,3-dione
  • pyridine
  • Dengue Virus
  • indoline
  • Virus Diseases
  10 Scopus citations

• Design, synthesis and biological evaluation of spiropyrazolopyridone derivatives as potent dengue virus inhibitors

  Xu, J., Xie, X., Chen, H., Zou, J., Xue, Y., Ye, N., Shi, P. Y. & Zhou, J., Jun 1 2020, In: Bioorganic and Medicinal Chemistry Letters. 30, 11, 127162.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Viruses
  • Substitution reactions
  • Nitrogen
  • Derivatives
  1 Scopus citations

• Determinants of dengue virus NS4A protein oligomerization

  Lee, C. M., Xie, X., Zou, J., Li, S. H., Qi Lee, M. Y., Dong, H., Qin, C. F., Kang, C. & Shi, P. Y., 2015, In: Journal of virology. 89, 12, p. 6171-6183 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus NS4A protein
  • Dengue virus
  • Flavivirus
  • oligomerization
  • Amino Acids
  24 Scopus citations

• Development and characterization of a stable eGFP enterovirus 71 for antiviral screening

  Shang, B., Deng, C., Ye, H., Xu, W., Yuan, Z., Shi, P. Y. & Zhang, B., Feb 2013, In: Antiviral research. 97, 2, p. 198-205 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Enterovirus
  • Antiviral Agents
  • Viruses
  • Vero Cells
  • Complementary DNA
  33 Scopus citations

• Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone

  Li, X. F., Dong, H. L., Wang, H. J., Huang, X. Y., Qiu, Y. F., Ji, X., Ye, Q., Li, C., Liu, Y., Deng, Y. Q., Jiang, T., Cheng, G., Zhang, F. C., Davidson, A. D., Song, Y. J., Shi, P. Y. & Qin, C. F., Dec 1 2018, In: Nature communications. 9, 1, 673.

  Research output: Contribution to journal › Article › peer-review

  • vaccines
  • Zika Virus
  • Flavivirus
  • Attenuated Vaccines
  • viruses
  45 Scopus citations

• Development of a Rapid Focus Reduction Neutralization Test Assay for Measuring SARS-CoV-2 Neutralizing Antibodies

  Vanderheiden, A., Edara, V. V., Floyd, K., Kauffman, R. C., Mantus, G., Anderson, E., Rouphael, N., Edupuganti, S., Shi, P. Y., Menachery, V. D., Wrammert, J. & Suthar, M. S., Dec 2020, In: Current Protocols in Immunology. 131, 1, e116.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus
  • Neutralization Tests
  • Neutralizing Antibodies
  • Vaccines
  • Coronavirus

• Development of a stable Gaussia luciferase enterovirus 71 reporter virus

  Xu, L. L., Shan, C., Deng, C. L., Li, X. D., Shang, B. D., Ye, H. Q., Liu, S. Q., Yuan, Z. M., Wang, Q. Y., Shi, P. Y. & Zhang, B., Jul 1 2015, In: Journal of Virological Methods. 219, p. 62-66 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Enterovirus
  • Luciferases
  • Viruses
  • Vero Cells
  • Drug Discovery
  8 Scopus citations

• Discovery of dengue virus NS4B inhibitors

  Wang, Q. Y., Dong, H., Zou, B., Karuna, R., Wan, K. F., Zou, J., Susila, A., Yip, A., Shan, C., Yeo, K. L., Xu, H., Ding, M., Chan, W. L., Gu, F., Seah, P. G., Liu, W., Lakshminarayana, S. B., Kang, C. B., Lescar, J., Blasco, F. & 2 others, Smith, P. W. & Shi, P. Y., 2015, In: Journal of virology. 89, 16, p. 8233-8244 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Dengue Virus
  • Inhibition (Psychology)
  • Amino Acids
  • Pharmaceutical Chemistry
  54 Scopus citations

• Dysregulation of Ephrin receptor and PPAR signaling pathways in neural progenitor cells infected by Zika virus

  Thulasi Raman, S. N., Latreille, E., Gao, J., Zhang, W., Wu, J., Russell, M. S., Walrond, L., Cyr, T., Lavoie, J. R., Safronetz, D., Cao, J., Sauve, S., Farnsworth, A., Chen, W., Shi, P. Y., Wang, Y., Wang, L., Rosu-Myles, M. & Li, X., Jan 1 2020, In: Emerging Microbes and Infections. 9, 1, p. 2046-2060 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Eph Family Receptors
  • Zika Virus
  • Neural Pathways
  • Microcephaly
  • Peroxisome Proliferator-Activated Receptors

• Enterovirus 71 VPg uridylation uses a two-molecular mechanism of 3D polymerase

  Sun, Y., Wang, Y., Shan, C., Chen, C., Xu, P., Song, M., Zhou, H., Yang, C., Xu, W., Shi, P. Y., Zhang, B. & Lou, Z., Dec 2012, In: Journal of virology. 86, 24, p. 13662-13671 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Enterovirus
  • Picornaviridae
  • RNA
  • mutation
  • Mutation
  32 Scopus citations

• Envelope protein ubiquitination drives entry and pathogenesis of Zika virus

  Giraldo, M. I., Xia, H., Aguilera-Aguirre, L., Hage, A., van Tol, S., Shan, C., Xie, X., Sturdevant, G. L., Robertson, S. J., McNally, K. L., Meade-White, K., Azar, S. R., Rossi, S. L., Maury, W., Woodson, M., Ramage, H., Johnson, J. R., Krogan, N. J., Morais, M. C., Best, S. M. & 2 others, Shi, P. Y. & Rajsbaum, R., Sep 17 2020, In: Nature. 585, 7825, p. 414-419 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Ubiquitination
  • Virus Internalization
  • Polyubiquitin
  • Proteins
  6 Scopus citations

• Evaluation of a novel reporter virus neutralization test for serological diagnosis of Zika and Dengue virus infection

  Shan, C., Ortiz, D. A., Yang, Y., Wong, S. J., Kramer, L. D., Shi, P. Y., Loeffelholz, M. J. & Ren, P., Oct 2017, In: Journal of Clinical Microbiology. 55, 10, p. 3028-3036 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus Infection
  • Zika Virus
  • Neutralization Tests
  • Dengue Virus
  • Viruses
  24 Scopus citations

• Evasion of Type I Interferon by SARS-CoV-2

  Xia, H., Cao, Z., Xie, X., Zhang, X., Chen, J. Y. C., Wang, H., Menachery, V. D., Rajsbaum, R. & Shi, P. Y., Oct 6 2020, In: Cell Reports. 33, 1, 108234.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Interferon Type I
  • Phosphorylation
  • Interferon Regulatory Factor-3
  24 Scopus citations

• Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes

  Liu, Y., Liu, J., Du, S., Shan, C., Nie, K., Zhang, R., Li, X. F., Zhang, R., Wang, T., Qin, C. F., Wang, P., Shi, P. Y. & Cheng, G., May 25 2017, In: Nature. 545, 7655, p. 482-486 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Aedes
  • Culicidae
  • Proteins
  • Epidemics
  193 Scopus citations