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• Article

  The role of sequence context, nucleotide pool balance and stress in 2'-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA

  Wang, J., Dong, H., Chionh, Y. H., Mcbee, M. E., Sirirungruang, S., Cunningham, R. P., Shi, P. Y. & Dedon, P. C., Oct 14 2016, In: Nucleic acids research. 44, 18, p. 8962-8975 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Bacterial RNA
  • Viral RNA
  • Deoxyribonucleotides
  • RNA
  • triphosphoric acid
  3 Scopus citations

• The stem region of premembrane protein plays an important role in the virus surface protein rearrangement during dengue maturation

  Zhang, Q., Hunke, C., Yau, Y. H., Seow, V., Lee, S., Tanner, L. B., Guan, X. L., Wenk, M. R., Fibriansah, G., Chew, P. L., Kukkaro, P., Biuković, G., Shi, P. Y., Shochat, S. G., Grüber, G. & Lok, S. M., Nov 23 2012, In: Journal of Biological Chemistry. 287, 48, p. 40525-40534 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Viruses
  • Dengue
  • Membrane Proteins
  • Exosomes
  • Dengue Virus
  32 Scopus citations

• The structural basis for serotype-specific neutralization of dengue virus by a human antibody

  Teoh, E. P., Kukkaro, P., Teo, E. W., Lim, A. P. C., Tan, T. T., Yip, A., Schul, W., Aung, M., Kostyuchenko, V. A., Leo, Y. S., Chan, S. H., Smith, K. G. C., Chan, A. H. Y., Zou, G., Ooi, E. E., Kemeny, D. M., Tan, G. K., Ng, J. K. W., Ng, M. L., Alonso, S. & 5 others, Fisher, D., Shi, P. Y., Hanson, B. J., Lok, S. M. & MacAry, P. A., Jun 20 2012, In: Science Translational Medicine. 4, 139, 139ra83.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Serogroup
  • Antibodies
  • Immunity
  • Cryoelectron Microscopy
  165 Scopus citations

• Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses

  Prasanth, K. R., Hirano, M., Fagg, W. S., McAnarney, E. T., Shan, C., Xie, X., Hage, A., Pietzsch, C. A., Bukreyev, A., Rajsbaum, R., Shi, P. Y., Bedford, M. T., Bradrick, S. S., Menachery, V. & Garcia-Blanco, M. A., Oct 2020, In: Antiviral research. 182, 104874.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA topoisomerase III
  • Yellow fever virus
  • SARS Virus
  • Dengue Virus
  • RNA Viruses
  3 Scopus citations

• Transmembrane domains of NS2B contribute to both viral RNA replication and particle formation in Japanese encephalitis virus

  Li, X. D., Deng, C. L., Ye, H. Q., Zhang, H. L., Zhang, Q. Y., Chen, D. D., Zhang, P. T., Shi, P. Y., Yuan, Z. M. & Zhang, B., Jun 1 2016, In: Journal of virology. 90, 12, p. 5735-5749 15 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA replication
  • Japanese encephalitis virus
  • Japanese Encephalitis Virus
  • Viral RNA
  • Protein Domains
  25 Scopus citations

• Treatment of human glioblastoma with a live attenuated Zika virus vaccine candidate

  Chen, Q., Wu, J., Ye, Q., Ma, F., Zhu, Q., Wu, Y., Shan, C., Xie, X., Li, D., Zhan, X., Li, C., Li, X. F., Qin, X., Zhao, T., Wu, H., Shi, P. Y., Man, J. & Qin, C. F., Sep 1 2018, In: mBio. 9, 5, e01683-18.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Glioblastoma
  • Vaccines
  • Glioma
  • Stem Cells
  32 Scopus citations

• Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies

  Arora, R., Liew, C. W., Soh, T. S., Otoo, D. A., Seh, C. C., Yue, K., Nilar, S., Wang, G., Yokokawa, F., Noble, C. G., Chen, Y. L., Shi, P. Y., Lescar, J., Smith, T. M., Benson, T. E. & Lim, S. P., Dec 2020, In: Journal of virology. 94, 24, e01130-20.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Dengue Virus
  • RNA Replicase
  • RNA-directed RNA polymerase
  • RNA

• U18666A, an intra-cellular cholesterol transport inhibitor, inhibits dengue virus entry and replication

  Poh, M. K., Shui, G., Xie, X., Shi, P. Y., Wenk, M. R. & Gu, F., Jan 2012, In: Antiviral research. 93, 1, p. 191-198 8 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one
  • Anticholesteremic Agents
  • Virus Internalization
  • Dengue Virus
  • Virus Replication
  72 Scopus citations

• Understanding zika virus stability and developing a chimeric vaccine through functional analysis

  Xie, X., Yang, Y., Muruato, A. E., Zou, J., Shan, C., Nunes, B. T. D., Medeiros, D. B. A., Vasconcelos, P. F. C., Weaver, S. C., Rossi, S. L. & Shi, P. Y., Jan 1 2017, In: mBio. 8, 1, e02134-16.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Vaccines
  • Viruses
  • Hydrogen
  • Virion
  62 Scopus citations

• Use of the immunoglobulin G avidity assay to differentiate between recent Zika and past dengue virus infections

  Furuya, A. K. M., Hunt, D., St. George, K., Dupuis, A. P., Kramer, L. D., Shi, P. Y. & Wong, S., Apr 15 2019, In: Clinical Science. 133, 7, p. 859-867 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Flavivirus
  • Microspheres
  • Immunoassay
  • Immunoglobulin G
  4 Scopus citations

• Using a virion assembly-defective dengue virus as a vaccine approach

  Shan, C., Xie, X., Zou, J., Züst, R., Zhang, B., Ambrose, R., Mackenzie, J., Fink, K. & Shi, P. Y., Nov 1 2018, In: Journal of virology. 92, 21, e01002.

  Research output: Contribution to journal › Article › peer-review

  • Defective Viruses
  • Dengue virus
  • Dengue Virus
  • virion
  • Virion
  10 Scopus citations

• Using next generation sequencing to study the genetic diversity of candidate live attenuated zika vaccines

  Collins, N. D., Shan, C., Nunes, B. T. D., Widen, S. G., Shi, P. Y., Barrett, A. D. T. & Sarathy, V. V., Apr 2020, In: Vaccines. 8, 2, 161.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus
  • Attenuated Vaccines
  • Genetic Variation
  • Membranes
  • Flaviviridae
  2 Scopus citations

• Using recombination-dependent lethal mutations to stabilize reporter flaviviruses for rapid serodiagnosis and drug discovery

  Baker, C., Xie, X., Zou, J., Muruato, A., Fink, K. & Shi, P. Y., Jul 2020, In: EBioMedicine. 57, 102838.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Drug Discovery
  • Flavivirus
  • Viruses
  • Serologic Tests
  • Genetic Recombination
  4 Scopus citations

• Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease

  Richner, J. M., Jagger, B. W., Shan, C., Fontes, C. R., Dowd, K. A., Cao, B., Himansu, S., Caine, E. A., Nunes, B. T. D., Medeiros, D. B. A., Muruato, A. E., Foreman, B. M., Luo, H., Wang, T., Barrett, A. D., Weaver, S. C., Vasconcelos, P. F. C., Rossi, S. L., Ciaramella, G., Mysorekar, I. U. & 3 others, Pierson, T. C., Shi, P. Y. & Diamond, M. S., Jul 13 2017, In: Cell. 170, 2, p. 273-283.e12

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Viruses
  • Vaccines
  • Glycosylation
  • Fetus
  124 Scopus citations

• Vesicular stomatitis virus and DNA vaccines expressing zika virus nonstructural protein 1 induce substantial but not sterilizing protection against zika virus infection

  Li, A., Xue, M., Attia, Z., Yu, J., Lu, M., Shan, C., Liang, X., Gao, T. Z., Shi, P. Y., Peeples, M. E., Boyaka, P. N., Liu, S. L. & Li, J., Sep 2020, In: Journal of virology. 94, 17, e00048-20.

  Research output: Contribution to journal › Article › peer-review

  • Zika virus
  • Zika Virus Infection
  • Zika Virus
  • recombinant vaccines
  • Vesiculovirus

• West Nile virus NS1 antagonizes interferon beta production by targeting RIG-I and MDA5

  Zhang, H. L., Ye, H. Q., Liu, S. Q., Deng, C. L., Li, X. D., Shi, P. Y. & Zhang, B., Sep 1 2017, In: Journal of virology. 91, 18, e02396-16.

  Research output: Contribution to journal › Article › peer-review

  • West Nile virus nonstructural protein 1
  • interferon-beta
  • West Nile virus
  • retinoic acid
  • Interferon-beta
  29 Scopus citations

• Zika structural genes determine the virulence of African and Asian lineages

  Nunes, B. T. D., Fontes-Garfias, C. R., Shan, C., Muruato, A. E., Nunes, J. G. C., Burbano, R. M. R., Vasconcelos, P. F. C., Shi, P. Y. & Medeiros, D. B. A., Jan 1 2020, In: Emerging Microbes and Infections. 9, 1, p. 1023-1033 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus
  • Virulence
  • Viruses
  • Epidemics
  • Genes

• Zika Virus: Diagnosis, Therapeutics, and Vaccine

  Shan, C., Xie, X., Barrett, A. D. T., Garcia-Blanco, M. A., Tesh, R. B., Vasconcelos, P. F. D. C., Vasilakis, N., Weaver, S. C. & Shi, P. Y., Mar 11 2016, In: ACS Infectious Diseases. 2, 3, p. 170-172 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Vaccines
  • Central America
  • South America
  • Global Health
  55 Scopus citations

• Zika virus epidemic in Brazil. I. Fatal disease in adults: Clinical and laboratorial aspects

  Azevedo, R. S. S., Araujo, M. T., Martins Filho, A. J., Oliveira, C. S., Nunes, B. T. D., Cruz, A. C. R., Nascimento, A. G. P. A. C., Medeiros, R. C., Caldas, C. A. M., Araujo, F. C., Quaresma, J. A. S., Vasconcelos, B. C. B., Queiroz, M. G. L., da Rosa, E. S. T., Henriques, D. F., Silva, E. V. P., Chiang, J. O., Martins, L. C., Medeiros, D. B. A., Lima, J. A. & 7 others, Nunes, M. R. T., Cardoso, J. F., Silva, S. P., Shi, P. Y., Tesh, R. B., Rodrigues, S. G. & Vasconcelos, P. F. C., Dec 1 2016, In: Journal of Clinical Virology. 85, p. 56-64 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus Infection
  • Zika Virus
  • Brazil
  • Epidemics
  • Microcephaly
  47 Scopus citations

• Zika virus has oncolytic activity against glioblastoma stem cells

  Zhu, Z., Gorman, M. J., McKenzie, L. D., Chai, J. N., Hubert, C. G., Prager, B. C., Fernandez, E., Richner, J. M., Zhang, R., Shan, C., Tycksen, E., Wang, X., Shi, P. Y., Diamond, M. S., Rich, J. N. & Chheda, M. G., 2017, In: Journal of Experimental Medicine. 214, 10, p. 2843-2857 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Glioblastoma
  • Stem Cells
  • Flavivirus
  • Oncolytic Virotherapy
  77 Scopus citations

• Zika virus infection elicits auto-antibodies to C1q

  Koma, T., Veljkovic, V., Anderson, D. E., Wang, L. F., Rossi, S. L., Shan, C., Shi, P. Y., Beasley, D. W., Bukreyeva, N., Smith, J. N., Hallam, S., Huang, C., Von Messling, V. & Paessler, S., Dec 1 2018, In: Scientific reports. 8, 1, 1882.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus Infection
  • Zika Virus
  • Antibodies
  • Complement C1q
  • Viral Structures
  10 Scopus citations

• Zika virus infects human Sertoli cells and modulates the integrity of the in vitro blood-testis barrier model

  Siemann, D. N., Strange, D. P., Maharaj, P. N., Shi, P. Y. & Verma, S., Nov 1 2017, In: Journal of virology. 91, 22, e00623-17.

  Research output: Contribution to journal › Article › peer-review

  • Zika virus
  • Blood-Testis Barrier
  • Zika Virus
  • Sertoli Cells
  • Sertoli cells
  46 Scopus citations

• Zika virus NS2A-mediated virion assembly

  Zhang, X., Xie, X., Xia, H., Zou, J., Huang, L., Popov, V. L., Chen, X. & Shi, P. Y., 2019, In: mBio. 10, 5, e02375-19.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus
  • Virion
  • Viral RNA
  • Flavivirus
  • RNA
  16 Scopus citations

• Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease

  Akiyama, B. M., Laurence, H. M., Massey, A. R., Costantino, D. A., Xie, X., Yang, Y., Shi, P. Y., Nix, J. C., Beckham, J. D. & Kieft, J. S., Dec 2 2016, In: Science. 354, 6316, p. 1148-1152 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Exonucleases
  • Untranslated RNA
  • Flavivirus
  • RNA
  107 Scopus citations

• Zika Virus Replicons for Drug Discovery

  Xie, X., Zou, J., Shan, C., Yang, Y., Kum, D. B., Dallmeier, K., Neyts, J. & Shi, P. Y., Oct 1 2016, In: EBioMedicine. 12, p. 156-160 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Drug Discovery
  • Replicon
  • Viruses
  • Cells
  46 Scopus citations
• Chapter

  Detection and quantification of flavivirus NS5 methyl-transferase activities

  Lim, S. P., Bodenreider, C. & Shi, P. Y., Jul 18 2013, Antiviral Methods and Protocols. p. 249-268 20 p. (Methods in Molecular Biology; vol. 1030).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Flavivirus
  • Thin Layer Chromatography
  • Transferases
  • mRNA guanylyltransferase
  • Fluorescence Polarization
  5 Scopus citations

• Discovery of potent non-nucleoside inhibitors of dengue viral RNA-dependent rna polymerase from fragment screening and structure-guided design

  Lim, S. P., Noble, C. G., Nilar, S., Shi, P. Y. & Yokokawa, F., 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 187-198 12 p. (Advances in Experimental Medicine and Biology; vol. 1062).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • RNA Replicase
  • Viruses
  • Dengue
  • DNA-Directed RNA Polymerases
  • Viral RNA
  4 Scopus citations

• Reverse genetics of Zika virus

  Shan, C., Xie, X. & Shi, P-Y., 2017, Methods in Molecular Biology. Humana Press Inc., Vol. 1602. p. 47-58 12 p. (Methods in Molecular Biology; vol. 1602).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Zika Virus
  • Reverse Genetics
  • Complementary DNA
  • Clone Cells
  • Hepatitis Delta Virus
  4 Scopus citations

• Testing Antiviral Compounds in a Dengue Mouse Model

  Schul, W., Yip, A. & Shi, P. Y., Jul 18 2013, Antiviral Methods and Protocols. p. 269-281 13 p. (Methods in Molecular Biology; vol. 1030).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Dengue Virus
  • Dengue
  • Antiviral Agents
  • Virus Diseases
  • Active Immunotherapy
  3 Scopus citations
• Comment/debate

  Adulthood Sequelae of Congenital Zika Virus Infection in Mice

  Zou, J. & Shi, P. Y., Jun 2017, In: EBioMedicine. 20, p. 11-12 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  3 Scopus citations

• Erratum: Zika virus has oncolytic activity against glioblastoma stem cells [The Journal of Experimental Medicine, 214, 10, (2017)] DOI: 10.1084/jem.20171093

  Zhu, Z., Gorman, M. J., McKenzie, L. D., Chai, J. N., Hubert, C. G., Prager, B. C., Fernandez, E., Richner, J. M., Zhang, R., Shan, C., Tycksen, E., Wang, X., Shi, P. Y., Diamond, M. S., Rich, J. N. & Chheda, M. G., 2017, In: Journal of Experimental Medicine. 214, 10, p. 3145 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Zika Virus
  • Biomedical Research
  • Glioblastoma
  • Emotions
  • Stem Cells
  6 Scopus citations

• Erratum: Treatment of human glioblastoma with a live attenuated zika virus vaccine candidate (mBio, (2018) 9(5), e01683-18, 10.1128/mBio.01683-18)

  Chen, Q., Wu, J., Ye, Q., Ma, F., Zhu, Q., Wu, Y., Shan, C., Xie, X., Li, D., Zhan, X., Li, C., Li, X. F., Qin, X., Zhao, T., Wu, H., Shi, P. Y., Man, J. & Qin, C. F., Mar 1 2019, In: mBio. 10, 2, e00433-19.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Zika Virus
  • Glioblastoma
  • Names
  • Vaccines

• Erratum to: Targeting vesicle size (Nature Materials, (2018), 17, 11, (955-956), 10.1038/s41563-018-0200-8)

  Fei, Z. & Shi, P. Y., Dec 1 2018, In: Nature Materials. 17, 12, p. 1164 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • news

• Targeting vesicle size

  Zou, J. & Shi, P. Y., Nov 1 2018, In: Nature Materials. 17, 11, p. 955-956 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • blood-brain barrier
  • Peptides
  • viruses
  • Viruses
  • peptides

• Zika virus: a new threat from mosquitoes

  Li, X. F., Han, J. F., Shi, P. Y. & Qin, C. F., Apr 1 2016, In: Science China. Life sciences. 59, 4, p. 440-442 3 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  13 Scopus citations
• Editorial

  Report of the fifth symposium on emerging viral diseases

  Zhang, B. & Shi, P. Y., Apr 2013, In: Virologica Sinica. 28, 2, p. 63-64 2 p.

  Research output: Contribution to journal › Editorial › peer-review
• Letter

  A single residue in the αb helix of the e protein is critical for Zika virus thermostability correspondence

  Xie, D. Y., Liu, Z. Y., Nian, Q. G., Zhu, L., Wang, N., Deng, Y. Q., Zhao, H., Ji, X., Li, X. F., Wang, X., Shi, P. Y. & Qin, C. F., Dec 1 2018, In: Emerging Microbes and Infections. 7, 1, 0006.

  Research output: Contribution to journal › Letter › peer-review
  3 Scopus citations
• Review article

  Antagonism of Type i Interferon by Severe Acute Respiratory Syndrome Coronavirus 2

  Xia, H. & Shi, P. Y., Dec 2020, In: Journal of Interferon and Cytokine Research. 40, 12, p. 543-548 6 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Interferons
  • Coronavirus Infections
  • Interferon Type I

• Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential

  Xu, J., Shi, P. Y., Li, H. & Zhou, J., May 8 2020, In: ACS Infectious Diseases. 6, 5, p. 909-915 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Niclosamide
  • Coronavirus
  • Antiviral Agents
  • Middle East Respiratory Syndrome Coronavirus
  • SARS Virus
  71 Scopus citations

• Did Zika Virus Mutate to Cause Severe Outbreaks?

  Rossi, S. L., Ebel, G. D., Shan, C., Shi, P. Y. & Vasilakis, N., Oct 2018, In: Trends in Microbiology. 26, 10, p. 877-885 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus
  • Disease Outbreaks
  • Venezuelan Equine Encephalitis Viruses
  • Chikungunya virus
  • Arboviruses
  12 Scopus citations

• Difficulties and advancements in developing drugs for the treatment of dengue fever

  Noble, C. G. & Shi, P. Y., 2013, In: Expert Opinion on Orphan Drugs. 1, 12, p. 947-949 3 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue
  • Dengue Virus
  • Antiviral Agents
  • Pharmaceutical Preparations
  • Culicidae
  1 Scopus citations

• Drug repurposing approach to combating coronavirus: Potential drugs and drug targets

  Xu, J., Xue, Y., Zhou, R., Shi, P. Y., Li, H. & Zhou, J., 2020, (Accepted/In press) In: Medicinal Research Reviews.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Drug Repositioning
  • Coronavirus
  • Severe Acute Respiratory Syndrome
  • Pandemics
  • Pharmaceutical Preparations

• Potential Mechanisms for Enhanced Zika Epidemic and Disease

  Xia, H., Xie, X., Shan, C. & Shi, P. Y., May 11 2018, In: ACS Infectious Diseases. 4, 5, p. 656-659 4 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus Infection
  • Epidemics
  • Herd Immunity
  • Flavivirus
  • Mutation
  5 Scopus citations

• Reserve genetic approaches for the development of Zika vaccines and therapeutics

  Fontes-Garfias, C. R., Baker, C. K. & Shi, P. Y., Oct 2020, In: Current Opinion in Virology. 44, p. 7-15 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus
  • Vaccines
  • Reverse Genetics
  • Epidemics
  • Antiviral Agents
  2 Scopus citations

• Small Molecules and Antibodies for Zika Therapy

  Xie, X., Zou, J., Shan, C. & Shi, P. Y., 2017, In: Journal of Infectious Diseases. 216, p. S945-S950

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus Infection
  • Zika Virus
  • Antibodies
  • Clinical Trials
  • Pregnant Women
  15 Scopus citations

• Strategies for Zika drug discovery

  Zou, J. & Shi, P. Y., Apr 2019, In: Current Opinion in Virology. 35, p. 19-26 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus
  • Drug Discovery
  • Vaccines
  • Antiviral Agents
  • Zika Virus Infection
  18 Scopus citations

• Structural biology of dengue virus enzymes: Towards rational design of therapeutics

  Noble, C. G. & Shi, P. Y., Nov 1 2012, In: Antiviral research. 96, 2, p. 115-126 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue Virus
  • Methyltransferases
  • Dengue
  • Enzymes
  • Peptide Hydrolases
  78 Scopus citations

• Ten years of dengue drug discovery: Progress and prospects

  Lim, S. P., Wang, Q. Y., Noble, C. G., Chen, Y. L., Dong, H., Zou, B., Yokokawa, F., Nilar, S., Smith, P., Beer, D., Lescar, J. & Shi, P. Y., 2013, In: Antiviral research. 100, 2, p. 500-519 20 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue Virus
  • Dengue
  • Drug Discovery
  • balapiravir
  • celgosivir
  241 Scopus citations

• Therapeutic potential of spirooxindoles as antiviral agents

  Ye, N., Chen, H., Wold, E. A., Shi, P. Y. & Zhou, J., Jun 10 2016, In: ACS Infectious Diseases. 2, 6, p. 382-392 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Antiviral Agents
  • Oxindoles
  • Dengue Virus
  • Structure-Activity Relationship
  • Dengue
  200 Scopus citations

• Type I and Type III interferons restrict SARS-CoV-2 infection of human airway epithelial cultures

  Vanderheiden, A., Ralfs, P., Chirkova, T., Upadhyay, A. A., Zimmerman, M. G., Bedoya, S., Aoued, H., Tharp, G. M., Pellegrini, K. L., Manfredi, C., Sorscher, E., Mainou, B., Lobby, J. L., Kohlmeier, J. E., Lowen, A. C., Shi, P. Y., Menachery, V. D., Anderson, L. J., Grakoui, A., Bosinger, S. E. & 1 others, Suthar, M. S., Oct 2020, In: Journal of virology. 94, 19, e00985-20.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Severe acute respiratory syndrome coronavirus
  • interferon type III
  • Coronavirus Infections
  • Severe Acute Respiratory Syndrome
  • interferons
  19 Scopus citations