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• Article

  Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin

  Gundermann, D. M., Walker, D. K., Reidy, P. T., Borack, M. S., Dickinson, J. M., Volpi, E. & Rasmussen, B. B., May 15 2014, In: American Journal of Physiology - Endocrinology and Metabolism. 306, 10, p. E1198-E1204

  Research output: Contribution to journal › Article › peer-review

  • Mechanistic Target of Rapamycin Complex 1
  • Sirolimus
  • Exercise
  • Muscles
  • Muscle Proteins
  51 Scopus citations

• AGS and NIA Bench-to Bedside Conference Summary: Osteoporosis and Soft Tissue (Muscle and Fat) Disorders

  Colón-Emeric, C., Whitson, H. E., Berry, S. D., Fielding, R. A., Houston, D. K., Kiel, D. P., Rosen, C. J., Seldeen, K. L., Volpi, E., White, J. P. & Troen, B. R., Jan 1 2020, In: Journal of the American Geriatrics Society. 68, 1, p. 31-38 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Muscular Diseases
  • Sarcopenia
  • Osteoporosis
  • Accidental Falls
  • Fats
  2 Scopus citations

• A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults

  Timmerman, K. L., Dhanani, S., Glynn, E. L., Fry, C. S., Drummond, M. J., Jennings, K., Rasmussen, B. B. & Volpi, E., Jun 1 2012, In: American Journal of Clinical Nutrition. 95, 6, p. 1403-1412 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Essential Amino Acids
  • Muscle Proteins
  • Sucrose
  • Nutrients
  • Insulin
  83 Scopus citations

• Androgen Therapy and Rehospitalization in Older Men with Testosterone Deficiency

  Baillargeon, J., Deer, R. R., Kuo, Y. F., Zhang, D., Goodwin, J. S. & Volpi, E., May 1 2016, In: Mayo Clinic Proceedings. 91, 5, p. 587-595 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Patient Readmission
  • Androgens
  • Testosterone
  • Odds Ratio
  • Medicare
  4 Scopus citations

• A randomized trial of a multifactorial strategy to prevent serious fall injuries

  Bhasin, S., Gill, T. M., Reuben, D. B., Latham, N. K., Ganz, D. A., Greene, E. J., Dziura, J., Basaria, S., Gurwitz, J. H., Dykes, P. C., McMahon, S., Storer, T. W., Gazarian, P., Miller, M. E., Travison, T. G., Esserman, D., Carnie, M. B., Goehring, L., Fagan, M., Greenspan, S. L. & 27 others, Alexander, N., Wiggins, J., Ko, F., Siu, A. L., Volpi, E., Wu, A. W., Rich, J., Waring, S. C., Wallace, R. B., Casteel, C., Resnick, N. M., Magaziner, J., Charpentier, P., Lu, C., Araujo, K., Rajeevan, H., Meng, C., Allore, H., Brawley, B. F., Eder, R., McGloin, J. M., Skokos, E. A., Duncan, P. W., Baker, D., Boult, C., Correa-De-Araujo, R. & Peduzzi, P., Jul 9 2020, In: New England Journal of Medicine. 383, 2, p. 129-140 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Accidental Falls
  • Wounds and Injuries
  • Control Groups
  • Patient Outcome Assessment
  • Nurses
  8 Scopus citations

• Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults

  Drummond, M. J., Dickinson, J. M., Fry, C. S., Walker, D. K., Gundermann, D. M., Reidy, P. T., Timmerman, K. L., Markofski, M. M., Paddon-Jones, D., Rasmussen, B. B. & Volpi, E., May 1 2012, In: American Journal of Physiology - Endocrinology and Metabolism. 302, 9, p. E1113-E1122

  Research output: Contribution to journal › Article › peer-review

  • Amino Acid Transport Systems
  • Essential Amino Acids
  • Mechanistic Target of Rapamycin Complex 1
  • Bed Rest
  • Muscle Proteins
  123 Scopus citations

• Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans

  Chondronikola, M., Volpi, E., Børsheim, E., Porter, C., Saraf, M. K., Annamalai, P., Yfanti, C., Chao, T., Wong, D., Shinoda, K., Labbe, S. M., Hurren, N. M., Cesani, F., Kajimura, S. & Sidossis, L. S., Jun 14 2016, In: Cell Metabolism. 23, 6, p. 1200-1206 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Brown Adipose Tissue
  • Lipid Metabolism
  • White Adipose Tissue
  • Nonesterified Fatty Acids
  • Cold Temperature
  133 Scopus citations

• Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans

  Chondronikola, M., Volpi, E., Børsheim, E., Porter, C., Annamalai, P., Enerbäck, S., Lidell, M. E., Saraf, M. K., Labbe, S. M., Hurren, N. M., Yfanti, C., Chao, T., Andersen, C. R., Cesani, F., Hawkins, H. & Sidossis, L. S., Dec 1 2014, In: Diabetes. 63, 12, p. 4089-4099 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brown Adipose Tissue
  • Insulin Resistance
  • Homeostasis
  • Glucose
  • Hypoglycemic Agents
  375 Scopus citations

• Brown adipose tissue is linked to a distinct thermoregulatory response to mild cold in people

  Chondronikola, M., Volpi, E., Børsheim, E., Chao, T., Porter, C., Annamalai, P., Yfanti, C., Labbe, S. M., Hurren, N. M., Malagaris, I., Cesani, F. & Sidossis, L. S., Apr 19 2016, In: Frontiers in Physiology. 7, APR, 129.

  Research output: Contribution to journal › Article › peer-review

  • Brown Adipose Tissue
  • Cold Temperature
  • Temperature
  • Body Temperature Regulation
  • Body Temperature
  23 Scopus citations

• D-CARE: The Dementia Care Study: Design of a Pragmatic Trial of the Effectiveness and Cost Effectiveness of Health System–Based Versus Community-Based Dementia Care Versus Usual Dementia Care

  Reuben, D. B., Gill, T. M., Stevens, A., Williamson, J., Volpi, E., Lichtenstein, M., Jennings, L. A., Tan, Z., Evertson, L., Bass, D., Weitzman, L., Carnie, M., Wilson, N., Araujo, K., Charpentier, P., Meng, C., Greene, E. J., Dziura, J., Liu, J., Unger, E. & 15 others, Yang, M., Currie, K., Lenoir, K. M., Green, A. NR. S., Abraham, S., Vernon, A., Samper-Ternent, R., Raji, M., Hirst, R. M., Galloway, R., Finney, G. R., Ladd, I., Rahm, A. K., Borek, P. & Peduzzi, P., Nov 2020, In: Journal of the American Geriatrics Society. 68, 11, p. 2492-2499 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Pragmatic Clinical Trials
  • Cost-Benefit Analysis
  • Dementia
  • Caregivers
  • Health

• Developing a screening tool for sarcopenia in hospitalized geriatric patients: Estimation of appendicular skeletal muscle mass using bioelectrical impedance

  Deer, R. R., Akhverdiyeva, L., Kuo, Y. F. & Volpi, E., Jul 2020, In: Clinical Nutrition. 39, 7, p. 2233-2237 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Sarcopenia
  • Electric Impedance
  • Geriatrics
  • Skeletal Muscle
  • Photon Absorptiometry
  1 Scopus citations

• Effect of essential amino acid supplementation and aerobic exercise on insulin sensitivity in healthy older adults: A randomized clinical trial

  Randolph, A. C., Markofski, M. M., Rasmussen, B. B. & Volpi, E., May 2020, In: Clinical Nutrition. 39, 5, p. 1371-1378 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Essential Amino Acids
  • Insulin Resistance
  • Randomized Controlled Trials
  • Exercise
  • Placebos

• Efficacy and safety of leucine supplementation in the elderly

  Borack, M. S. & Volpi, E., Dec 1 2016, In: Journal of Nutrition. 146, 12, p. 2625S-2629S

  Research output: Contribution to journal › Article › peer-review

  • Leucine
  • Elderly
  • Safety
  • Anabolic Agents
  • Muscles
  25 Scopus citations

• Essential amino acid ingestion alters expression of genes associated with amino acid sensing, transport, and mTORC1 regulation in human skeletal muscle

  Graber, T. G., Borack, M. S., Reidy, P. T., Volpi, E. & Rasmussen, B. B., May 11 2017, In: Nutrition and Metabolism. 14, 1, 35.

  Research output: Contribution to journal › Article › peer-review

  • Essential Amino Acids
  • Mechanistic Target of Rapamycin Complex 1
  • Skeletal Muscle
  • Eating
  • Amino Acids
  9 Scopus citations

• Identifying effective and feasible interventions to accelerate functional recovery from hospitalization in older adults: A randomized controlled pilot trial

  Deer, R. R., Dickinson, J. M., Fisher, S. R., Ju, H. & Volpi, E., Jul 1 2016, In: Contemporary Clinical Trials. 49, p. 6-14 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Hospitalization
  • Randomized Controlled Trials
  • Geriatrics
  • Rehabilitation
  • Placebos
  11 Scopus citations

• Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells

  Walker, D. K., Drummond, M. J., Dickinson, J. M., Borack, M. S., Jennings, K., Volpi, E. & Rasmussen, B. B., Mar 2014, In: Physiological reports. 2, 3, e00238.

  Research output: Contribution to journal › Article › peer-review

  • Large Neutral Amino Acid-Transporter 1
  • Amino Acid Transport Systems
  • Mechanistic Target of Rapamycin Complex 1
  • Muscle Cells
  • Skeletal Muscle
  21 Scopus citations

• Leucine-enriched Amino acid ingestion after resistance exercise prolongs myofibrillar protein synthesis and amino acid transporter expression in older men

  Dickinson, J. M., Gundermann, D. M., Walker, D. K., Reidy, P. T., Borack, M. S., Drummond, M. J., Arora, M., Volpi, E. & Rasmussen, B. B., 2014, In: Journal of Nutrition. 144, 11, p. 1694-1702 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Amino Acid Transport Systems
  • Leucine
  • Eating
  • Amino Acids
  • Exercise
  56 Scopus citations

• Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women

  Chondronikola, M., Asghar, R., Zhang, X., Dillon, E. L., Durham, W. J., Wu, Z., Porter, C., Camacho-Hughes, M., Zhao, Y., Brasier, A. R., Volpi, E., Sheffield-Moore, M., Abate, N., Sidossis, L. & Tuvdendorj, D., Oct 2017, In: Clinical Nutrition. 36, 5, p. 1310-1319 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Carnitine
  • Blood Cells
  • Palmitates
  • Insulin Resistance
  • Hyperinsulinism
  2 Scopus citations

• PAX7+ satellite cells in young and older adults following resistance exercise

  Walker, D. K., Fry, C. S., Drummond, M. J., Dickinson, J. M., Timmerman, K. L., Gundermann, D. M., Jennings, K., Volpi, E. & Rasmussen, B. B., Jul 2012, In: Muscle and Nerve. 46, 1, p. 51-59 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Young Adult
  • Exercise
  • Cyclin-Dependent Kinase Inhibitor p27
  • Cyclin-Dependent Kinase 2
  • Muscle Proteins
  27 Scopus citations

• Post-absorptive muscle protein turnover affects resistance training hypertrophy

  Reidy, P. T., Borack, M. S., Markofski, M. M., Dickinson, J. M., Fry, C. S., Deer, R. R., Volpi, E. & Rasmussen, B. B., May 1 2017, In: European Journal of Applied Physiology. 117, 5, p. 853-866 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Muscle Proteins
  • Resistance Training
  • Hypertrophy
  • Exercise
  • Muscles
  17 Scopus citations

• Protein supplementation does not affect myogenic adaptations to resistance training

  Reidy, P. T., Fry, C. S., Igbinigie, S., Deer, R. R., Jennings, K., Cope, M. B., Mukherjea, R., Volpi, E. & Rasmussen, B. B., 2017, In: Medicine and Science in Sports and Exercise. 49, 6, p. 1197-1208 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Resistance Training
  • Proteins
  • Hypertrophy
  • Exercise
  • Muscles
  20 Scopus citations

• Protein supplementation has minimal effects on muscle adaptations during resistance exercise training in young men: A double-blind randomized clinical trial

  Reidy, P. T., Borack, M. S., Markofski, M. M., Dickinson, J. M., Deer, R. R., Husaini, S. H., Walker, D. K., Igbinigie, S., Robertson, S. M., Cope, M. B., Mukherjea, R., Hall-Porter, J. M., Jennings, K., Volpi, E. & Rasmussen, B. B., 2016, In: Journal of Nutrition. 146, 9, p. 1660-1669 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Resistance Training
  • Randomized Controlled Trials
  • Exercise
  • Muscles
  • Proteins
  28 Scopus citations

• Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling

  Matveyenko, A. V., Liuwantara, D., Gurlo, T., Kirakossian, D., Dalla Man, C., Cobelli, C., White, M. F., Copps, K. D., Volpi, E., Fujita, S. & Butler, P. C., Sep 2012, In: Diabetes. 61, 9, p. 2269-2279 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Portal Vein
  • Insulin
  • Liver
  • Insulin Secretion
  • Glucokinase
  81 Scopus citations

• Reactive hyperemia is not responsible for stimulating muscle protein synthesis following blood flow restriction exercise

  Gundermann, D. M., Fry, C. S., Dickinson, J. M., Walker, D. K., Timmerman, K. L., Drummond, M. J., Volpi, E. & Rasmussen, B. B., May 1 2012, In: Journal of Applied Physiology. 112, 9, p. 1520-1528 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Muscle Proteins
  • Hyperemia
  • Exercise
  • Mechanistic Target of Rapamycin Complex 1
  • TOR Serine-Threonine Kinases
  55 Scopus citations

• Resistance exercise training promotes fiber type-specific myonuclear adaptations in older adults

  Moro, T., Brightwell, C. R., Volpi, E., Rasmussen, B. B. & Fry, C. S., 2020, In: Journal of Applied Physiology. 128, 4, p. 795-804 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Resistance Training
  • Myosin Heavy Chains
  • Exercise
  • Skeletal Muscle Fibers
  • Lipids
  2 Scopus citations

• Soy-dairy protein blend and whey protein ingestion after resistance exercise increases amino acid transport and transporter expression in human skeletal muscle

  Reidy, P. T., Walker, D. K., Dickinson, J. M., Gundermann, D. M., Drummond, M. J., Timmerman, K. L., Cope, M. B., Mukherjea, R., Jennings, K., Volpi, E. & Rasmussen, B. B., Jun 1 2014, In: Journal of Applied Physiology. 116, 11, p. 1353-1364 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Whey Proteins
  • Soybean Proteins
  • Amino Acid Transport Systems
  • Skeletal Muscle
  • Eating
  50 Scopus citations

• Soy-dairy protein blend or whey protein isolate ingestion induces similar postexercise muscle mechanistic target of rapamycin complex 1 signaling and protein synthesis responses in older men

  Borack, M. S., Reidy, P. T., Husaini, S. H., Markofski, M. M., Deer, R. R., Richison, A. B., Lambert, B. S., Cope, M. B., Mukherjea, R., Jennings, K., Volpi, E. & Rasmussen, B. B., Dec 1 2016, In: Journal of Nutrition. 146, 12, p. 2468-2475 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Whey Proteins
  • Soybean Proteins
  • Mechanistic Target of Rapamycin Complex 1
  • Eating
  • Muscle Proteins
  25 Scopus citations

• Testing the effects of narrative and play on physical activity among breast cancer survivors using mobile apps: Study protocol for a randomized controlled trial

  Lyons, E. J., Baranowski, T., Basen-Engquist, K. M., Lewis, Z. H., Swartz, M. C., Jennings, K. & Volpi, E., Mar 9 2016, In: BMC Cancer. 16, 1, 202.

  Research output: Contribution to journal › Article › peer-review

  • Mobile Applications
  • Cancer Survivors
  • Randomized Controlled Trials
  • Exercise
  • Breast Neoplasms
  18 Scopus citations

• The impact of postexercise essential amino acid ingestion on the ubiquitin proteasome and autophagosomal-lysosomal systems in skeletal muscle of older men

  Dickinson, J. M., Reidy, P. T., Gundermann, D. M., Borack, M. S., Walker, D. K., D'Lugos, A. C., Volpi, E. & Rasmussen, B. B., Mar 2017, In: Journal of Applied Physiology. 122, 3, p. 620-630 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Essential Amino Acids
  • Proteasome Endopeptidase Complex
  • Leucine
  • Ubiquitin
  • Skeletal Muscle
  14 Scopus citations

• Vitamin D and endothelial vasodilation in older individuals: Data from the PIVUS study

  Maggio, M., De Vita, F., Lauretani, F., Ceda, G. P., Volpi, E., Giallauria, F., De Cicco, G., Cattabiani, C., Melhus, H., Michaëlsson, K., Cederholm, T. & Lind, L., Sep 1 2014, In: Journal of Clinical Endocrinology and Metabolism. 99, 9, p. 3382-3389 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Vasodilation
  • Vitamin D
  • Prospective Studies
  • Endothelium
  • Kidney Function Tests
  10 Scopus citations
• Chapter

  Muscle Biology and mTORC1 Signaling in Aging

  Rasmussen, B. B. & Volpi, E., Jul 27 2012, Sarcopenia. John Wiley and Sons, p. 20-40 21 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  1 Scopus citations

• Muscle Biology and mTORC1 Signaling in Aging

  Rasmussen, B. B. & Volpi, E., 2012, Sarcopenia. Cruz-Jentoft, A. J. & Morley, J. E. (eds.). 1st ed. Wiley-Blackwell, p. 20-40

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  1 Scopus citations
• Review article

  Molecular Transducers of Physical Activity Consortium (MoTrPAC): Mapping the Dynamic Responses to Exercise

  the Molecular Transducers of Physical Activity Consortium, Jun 25 2020, In: Cell. 181, 7, p. 1464-1474 11 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Transducers
  • Dynamic response
  • Tissue
  • Rodentia
  8 Scopus citations

• Sex Hormones and Novel Corona Virus Infectious Disease (COVID-19)

  Al-Lami, R. A., Urban, R. J., Volpi, E., Algburi, A. M. A. & Baillargeon, J., Aug 2020, In: Mayo Clinic Proceedings. 95, 8, p. 1710-1714 5 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Coronavirus
  • Gonadal Steroid Hormones
  • Communicable Diseases
  • Virus Diseases
  • Testosterone
  9 Scopus citations