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Article

Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin

Gundermann, D. M., Walker, D. K., Reidy, P. T., Borack, M. S., Dickinson, J. M., Volpi, E. & Rasmussen, B. B., May 15 2014, In: American Journal of Physiology - Endocrinology and Metabolism. 306, 10, p. E1198-E1204

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Age-related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation

Tanner, R. E., Brunker, L. B., Agergaard, J., Barrows, K. M., Briggs, R. A., Kwon, O. S., Young, L. M., Hopkins, P. N., Volpi, E., Marcus, R. L., Lastayo, P. C. & Drummond, M. J., Sep 1 2015, In: Journal of Physiology. 593, 18, p. 4259-4273 15 p.

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

AGS and NIA Bench-to Bedside Conference Summary: Osteoporosis and Soft Tissue (Muscle and Fat) Disorders

Colón-Emeric, C., Whitson, H. E., Berry, S. D., Fielding, R. A., Houston, D. K., Kiel, D. P., Rosen, C. J., Seldeen, K. L., Volpi, E., White, J. P. & Troen, B. R., Jan 1 2020, In: Journal of the American Geriatrics Society. 68, 1, p. 31-38 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

A phase I randomized clinical trial of evidence-based, pragmatic interventions to improve functional recovery after hospitalization in geriatric patients

Deer, R. R., Dickinson, J. M., Baillargeon, J., Fisher, S. R., Raji, M. & Volpi, E., Oct 1 2019, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 10, p. 1628-1636 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

A randomized controlled pilot trial of interventions to improve functional recovery after hospitalization in older adults: Feasibility and adherence

Deer, R. R., Goodlett, S. M., Fisher, S. R., Baillargeon, J., Dickinson, J. M., Raji, M. & Volpi, E., Mar 1 2018, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 2, p. 187-193 7 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

A randomized trial of a multifactorial strategy to prevent serious fall injuries

Bhasin, S., Gill, T. M., Reuben, D. B., Latham, N. K., Ganz, D. A., Greene, E. J., Dziura, J., Basaria, S., Gurwitz, J. H., Dykes, P. C., McMahon, S., Storer, T. W., Gazarian, P., Miller, M. E., Travison, T. G., Esserman, D., Carnie, M. B., Goehring, L., Fagan, M., Greenspan, S. L. & 27 others, Alexander, N., Wiggins, J., Ko, F., Siu, A. L., Volpi, E., Wu, A. W., Rich, J., Waring, S. C., Wallace, R. B., Casteel, C., Resnick, N. M., Magaziner, J., Charpentier, P., Lu, C., Araujo, K., Rajeevan, H., Meng, C., Allore, H., Brawley, B. F., Eder, R., McGloin, J. M., Skokos, E. A., Duncan, P. W., Baker, D., Boult, C., Correa-De-Araujo, R. & Peduzzi, P., Jul 9 2020, In: New England Journal of Medicine. 383, 2, p. 129-140 12 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans

Chondronikola, M., Volpi, E., Børsheim, E., Porter, C., Annamalai, P., Enerbäck, S., Lidell, M. E., Saraf, M. K., Labbe, S. M., Hurren, N. M., Yfanti, C., Chao, T., Andersen, C. R., Cesani, F., Hawkins, H. & Sidossis, L. S., Dec 1 2014, In: Diabetes. 63, 12, p. 4089-4099 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

374 Scopus citations

D-CARE: The Dementia Care Study: Design of a Pragmatic Trial of the Effectiveness and Cost Effectiveness of Health System–Based Versus Community-Based Dementia Care Versus Usual Dementia Care

Reuben, D. B., Gill, T. M., Stevens, A., Williamson, J., Volpi, E., Lichtenstein, M., Jennings, L. A., Tan, Z., Evertson, L., Bass, D., Weitzman, L., Carnie, M., Wilson, N., Araujo, K., Charpentier, P., Meng, C., Greene, E. J., Dziura, J., Liu, J., Unger, E. & 15 others, Yang, M., Currie, K., Lenoir, K. M., Green, A. NR. S., Abraham, S., Vernon, A., Samper-Ternent, R., Raji, M., Hirst, R. M., Galloway, R., Finney, G. R., Ladd, I., Rahm, A. K., Borek, P. & Peduzzi, P., Nov 2020, In: Journal of the American Geriatrics Society. 68, 11, p. 2492-2499 8 p.

Research output: Contribution to journal › Article › peer-review

Developing a screening tool for sarcopenia in hospitalized geriatric patients: Estimation of appendicular skeletal muscle mass using bioelectrical impedance

Deer, R. R., Akhverdiyeva, L., Kuo, Y. F. & Volpi, E., Jul 2020, In: Clinical Nutrition. 39, 7, p. 2233-2237 5 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Effect of aerobic exercise training and essential amino acid supplementation for 24 weeks on physical function, body composition, and muscle metabolism in healthy, independent older adults: A randomized clinical trial

Markofski, M. M., Jennings, K., Timmerman, K. L., Dickinson, J. M., Fry, C. S., Borack, M. S., Reidy, P. T., Deer, R. R., Randolph, A., Rasmussen, B. B. & Volpi, E., Oct 1 2019, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 10, p. 1598-1604 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

Markofski, M. M., Dickinson, J. M., Drummond, M. J., Fry, C. S., Fujita, S., Gundermann, D. M., Glynn, E. L., Jennings, K., Paddon-Jones, D., Reidy, P. T., Sheffield-Moore, M., Timmerman, K. L., Rasmussen, B. B. & Volpi, E., May 1 2015, In: Experimental Gerontology. 65, p. 1-7 7 p.

Research output: Contribution to journal › Article › peer-review

65 Scopus citations

Effect of a Multifactorial Fall Injury Prevention Intervention on Patient Well-Being: The STRIDE Study

Gill, T. M., Bhasin, S., Reuben, D. B., Latham, N. K., Araujo, K., Ganz, D. A., Boult, C., Wu, A. W., Magaziner, J., Alexander, N., Wallace, R. B., Miller, M. E., Travison, T. G., Greenspan, S. L., Gurwitz, J. H., Rich, J., Volpi, E., Waring, S. C., Manini, T. M., Min, L. C. & 26 others, Teresi, J., Dykes, P. C., McMahon, S., McGloin, J. M., Skokos, E. A., Charpentier, P., Basaria, S., Duncan, P. W., Storer, T. W., Gazarian, P., Allore, H. G., Dziura, J., Esserman, D., Carnie, M. B., Hanson, C., Ko, F., Resnick, N. M., Wiggins, J., Lu, C., Meng, C., Goehring, L., Fagan, M., Correa-de-Araujo, R., Casteel, C., Peduzzi, P. & Greene, E. J., 2020, (Accepted/In press) In: Journal of the American Geriatrics Society.

Research output: Contribution to journal › Article › peer-review

Effect of essential amino acid supplementation and aerobic exercise on insulin sensitivity in healthy older adults: A randomized clinical trial

Randolph, A. C., Markofski, M. M., Rasmussen, B. B. & Volpi, E., May 2020, In: Clinical Nutrition. 39, 5, p. 1371-1378 8 p.

Research output: Contribution to journal › Article › peer-review

Effect of high-fat diet on peripheral blood mononuclear cells and adipose tissue in early stages of diet-induced weight gain

Lowry, J. E., Tumurbaatar, B., D'agostino, C., Main, E., Wright, T. J., Dillon, E. L., Saito, T. B., Porter, C., Andersen, C. R., Brining, D. L., Endsley, J. J., Sheffield-Moore, M., Volpi, E., Fang, R., Abate, N. & Tuvdendorj, D. R., Dec 28 2019, In: British Journal of Nutrition. 122, 12, p. 1359-1367 9 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Essential amino acid ingestion alters expression of genes associated with amino acid sensing, transport, and mTORC1 regulation in human skeletal muscle

Graber, T. G., Borack, M. S., Reidy, P. T., Volpi, E. & Rasmussen, B. B., May 11 2017, In: Nutrition and Metabolism. 14, 1, 35.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans

Glynn, E. L., Piner, L. W., Huffman, K. M., Slentz, C. A., Elliot-Penry, L., AbouAssi, H., White, P. J., Bain, J. R., Muehlbauer, M. J., Ilkayeva, O. R., Stevens, R. D., Porter Starr, K. N., Bales, C. W., Volpi, E., Brosnan, M. J., Trimmer, J. K., Rolph, T. P., Newgard, C. B. & Kraus, W. E., Aug 9 2015, In: Diabetologia. 58, 10, p. 2324-2335 12 p.

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells

Walker, D. K., Drummond, M. J., Dickinson, J. M., Borack, M. S., Jennings, K., Volpi, E. & Rasmussen, B. B., 2014, In: Physiological reports. 2, 3, e00238.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Leucine-enriched Amino acid ingestion after resistance exercise prolongs myofibrillar protein synthesis and amino acid transporter expression in older men

Dickinson, J. M., Gundermann, D. M., Walker, D. K., Reidy, P. T., Borack, M. S., Drummond, M. J., Arora, M., Volpi, E. & Rasmussen, B. B., 2014, In: Journal of Nutrition. 144, 11, p. 1694-1702 9 p.

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults

Moro, T., Brightwell, C. R., Phalen, D. E., McKenna, C. F., Lane, S. J., Porter, C., Volpi, E., Rasmussen, B. B. & Fry, C. S., Nov 2019, In: Experimental Gerontology. 127, 110723.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle

Porter, C., Hurren, N. M., Cotter, M. V., Bhattarai, N., Reidy, P. T., Dillon, E., Durham, W. J., Tuvdendorj, D., Sheffield-Moore, M., Volpi, E., Sidossis, L. S., Rasmussen, B. & Børsheim, E., Aug 5 2015, In: American Journal of Physiology - Endocrinology and Metabolism. 309, 3, p. E224-E232

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Muscle protein anabolic resistance to essential amino acids does not occur in healthy older adults before or after resistance exercise training

Moro, T., Brightwell, C. R., Deer, R. R., Graber, T. G., Galvan, E., Fry, C. S., Volpi, E. & Rasmussen, B. B., Jun 1 2018, In: Journal of Nutrition. 148, 6, p. 900-909 10 p.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women

Chondronikola, M., Asghar, R., Zhang, X., Dillon, E. L., Durham, W. J., Wu, Z., Porter, C., Camacho-Hughes, M., Zhao, Y., Brasier, A. R., Volpi, E., Sheffield-Moore, M., Abate, N., Sidossis, L. & Tuvdendorj, D., Oct 2017, In: Clinical Nutrition. 36, 5, p. 1310-1319 10 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Post-absorptive muscle protein turnover affects resistance training hypertrophy

Reidy, P. T., Borack, M. S., Markofski, M. M., Dickinson, J. M., Fry, C. S., Deer, R. R., Volpi, E. & Rasmussen, B. B., May 1 2017, In: European Journal of Applied Physiology. 117, 5, p. 853-866 14 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Protein supplementation does not affect myogenic adaptations to resistance training

Reidy, P. T., Fry, C. S., Igbinigie, S., Deer, R. R., Jennings, K., Cope, M. B., Mukherjea, R., Volpi, E. & Rasmussen, B. B., 2017, In: Medicine and Science in Sports and Exercise. 49, 6, p. 1197-1208 12 p.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Protocol for serious fall injury adjudication in the Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) study

Ganz, D. A., Siu, A. L., Magaziner, J., Latham, N. K., Travison, T. G., Lorenze, N. P., Lu, C., Wang, R., Greene, E. J., Stowe, C. L., Harvin, L. N., Araujo, K. L. B., Gurwitz, J. H., Agrawal, Y., Correa-De-Araujo, R., Peduzzi, P., Gill, T. M., Bhasin, S., Gill, T. M., Reuben, D. B. & 149 others, McMahon, S., Latham, N. K., Basaria, S., Brawley, B., Eder, R., Larson, A., Goehring, L., Lukas, M., Margolis, S., Storer, T. W., Carnie, M. B., Gazarian, P., Fagan, M., Peduzzi, P., Dziura, J., Esserman, D., Greene, E. J., Hawthorne-Jones, G., Allore, H., Doyle, M., Funaro, B., Lorenze, N., Mignosa, B., Miller, M. E., Travison, T. G., Charpentier, P., Araujo, K., Baker, D., McGloin, J. M., Lu, C., Rajeevan, H., Katsovich, L., Wang, R., Shelton, A., Skokos, E., Tang, S., Abella, M., Gordon, C., Pennestri, T., Bianco, L., Castro, R., Rubeck, S., Rando, K., Foster, B., Wu, K., Nock, D., Collins, C., Sherman, L., Waring, S. C., Chopskie, E., Larsen, H., Taran, A., Bianco, J., Hoberg, M., Rich, J., Chavez, V., Moore, C., Howe, J., Garcia, R., Nunez, J., Ho, S., Chen, Y., Wu, A. W., Walston, J. D., Agrawal, Y., Ephraim, P., Campbell, T., Albert, M., Ashar, B., Birnbaum, B., Chaudry, S., Edwards, L. T., Feeser, S., Hussain, N., Joseph, A., Larsen, K., Lee, A., Okuwobi, O., Scheck, T., Wallace, R., Casteel, C., Shanahan, A., Weldon, J., Leveke, A., Keller, C., Reist, J., Alexander, N., Wiggins, J., Burek, K., Ledesma, T., Nyquist, L. V., Gallagher, N., Hanson, C., Ko, F., Siu, A. L., Leipzig, R. M., Espino, C., Ramaswamy, R., West, D., Matza, D., Dykes, P., Stenvig, H., Florgomes, K., Christiansen, T., Salazar, A., Frain, L., Orkaby, A., Bean, J., Wells, Y., Foskett, C., Gurwitz, J. H., Richards, A., Amroze, A., Garber, L., Preusse, P., McDonald, A., Greenspan, S. L., Ferchak, M. A., Rigatti, M., Madia, J., Volpi, E., Hirst, R., Martinez, E., Raji, M., Magaziner, J., Ganz, D. A., Duncan, P. W., Boult, C., Goodwin, J., Manini, T., High, K. P., Harvin, L., Stowe, C., Romashkan, S., Correa-De-Araujo, R., Joseph, L., Salive, M., Hadley, E. C., Clauser, S. B., Buchner, D., Fulmer, T., Ellenberg, S., Beattie, B. L., King, A. C., Brown, C. J., Rubenstein, L., Sterling, M. A., Prohaska, T. & Friedman, L., Apr 15 2019, In: Injury Epidemiology. 6, 1, 14.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Quantification of muscle triglyceride synthesis rate requires an adjustment for total triglyceride content

Asghar, R., Chondronikola, M., Dillon, E. L., Durham, W. J., Porter, C., Wu, Z., Camacho-Hughes, M., Andersen, C. R., Spratt, H., Volpi, E., Sheffield-Moore, M., Sidossis, L., Wolfe, R. R., Abate, N. & Tuvdendorj, D. R., 2018, In: Journal of Lipid Research. 59, 10, p. 2018-2024 7 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Resistance exercise training promotes fiber type-specific myonuclear adaptations in older adults

Moro, T., Brightwell, C. R., Volpi, E., Rasmussen, B. B. & Fry, C., Jan 1 2020, In: Journal of Applied Physiology. 128, 4, p. 795-804 10 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Sex-dependent difference in the relationship between adipose-tissue cholesterol efflux and estradiol concentrations in young healthy humans

Iqbal, F., Durham, W. J., Melhem, A., Raslan, S., Tran, T. T., Wright, T. J., Asghar, R., Fujise, K., Volpi, E., Sidossis, L., Abate, N., Sheffield-Moore, M. & Tuvdendorj, D., Feb 2018, In: International Journal of Developmental Neuroscience. 64, p. 59-62 4 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Soy-dairy protein blend and whey protein ingestion after resistance exercise increases amino acid transport and transporter expression in human skeletal muscle

Reidy, P. T., Walker, D. K., Dickinson, J. M., Gundermann, D. M., Drummond, M. J., Timmerman, K. L., Cope, M. B., Mukherjea, R., Jennings, K., Volpi, E. & Rasmussen, B. B., Jun 1 2014, In: Journal of Applied Physiology. 116, 11, p. 1353-1364 12 p.

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Strategies to reduce injuries and develop confidence in elders (STRIDE): A cluster-randomized pragmatic trial of a multifactorial fall injury prevention strategy: Design and methods

Bhasin, S., Gill, T. M., Reuben, D. B., Latham, N. K., Gurwitz, J. H., Dykes, P., McMahon, S., Storer, T. W., Duncan, P. W., Ganz, D. A., Basaria, S., Miller, M. E., Travison, T. G., Greene, E. J., Dziura, J., Esserman, D., Allore, H., Carnie, M. B., Fagan, M., Hanson, C. & 25 others, Baker, D., Greenspan, S. L., Alexander, N., Ko, F., Siu, A. L., Volpi, E., Wu, A. W., Rich, J., Waring, S. C., Wallace, R., Casteel, C., Magaziner, J., Charpentier, P., Lu, C., Araujo, K., Rajeevan, H., Margolis, S., Eder, R., McGloin, J. M., Skokos, E., Wiggins, J., Garber, L., Clauser, S. B., Correa-De-Araujo, R. & Peduzzi, P., 2018, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 8, p. 1053-1061 9 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

The impact of postexercise essential amino acid ingestion on the ubiquitin proteasome and autophagosomal-lysosomal systems in skeletal muscle of older men

Dickinson, J. M., Reidy, P. T., Gundermann, D. M., Borack, M. S., Walker, D. K., D'Lugos, A. C., Volpi, E. & Rasmussen, B. B., Mar 2017, In: Journal of Applied Physiology. 122, 3, p. 620-630 11 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Tricyclic Antidepressant and/or γ-Aminobutyric Acid–Analog Use Is Associated With Fall Risk in Diabetic Peripheral Neuropathy

Randolph, A. C., Lin, Y. L., Volpi, E. & Kuo, Y. F., Jun 2019, In: Journal of the American Geriatrics Society. 67, 6, p. 1174-1181 8 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Use of the short physical performance battery and step monitoring to evaluate improvements after epidural steroid injections in an elderly patient

Przkora, R., Fisher, S. R., Von Der Hoeh, N., Heyde, C. E., Dominguez, J. D., Maybauer, M. O. & Volpi, E., Jun 1 2015, In: Journal of Clinical Gerontology and Geriatrics. 6, 2, p. 68-70 3 p., 139.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Vitamin D and endothelial vasodilation in older individuals: Data from the PIVUS study

Maggio, M., De Vita, F., Lauretani, F., Ceda, G. P., Volpi, E., Giallauria, F., De Cicco, G., Cattabiani, C., Melhus, H., Michaëlsson, K., Cederholm, T. & Lind, L., Sep 1 2014, In: Journal of Clinical Endocrinology and Metabolism. 99, 9, p. 3382-3389 8 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Whey protein hydrolysate increases amino acid uptake, mTORC1 signaling, and protein synthesis in skeletal muscle of healthy young men in a randomized crossover trial

Moro, T., Brightwell, C. R., Velarde, B., Fry, C. S., Nakayama, K., Sanbongi, C., Volpi, E. & Rasmussen, B. B., 2019, In: Journal of Nutrition. 149, 7, p. 1149-1158 10 p.

Research output: Contribution to journal › Article › peer-review