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• Short survey

  Ribonucleases and bacterial virulence

  Lawal, A., Jejelowo, O., Chopra, A. K. & Rosenzweig, J. A., Sep 2011, In: Microbial Biotechnology. 4, 5, p. 558-571 14 p.

  Research output: Contribution to journal › Short survey › peer-review

  • Ribonucleases
  • Virulence
  • Bacteria
  • Aeromonas hydrophila
  • Shigella flexneri
  16 Scopus citations
• Review article

  Low-shear force associated with modeled microgravity and spaceflight does not similarly impact the virulence of notable bacterial pathogens

  Rosenzweig, J. A., Ahmed, S., Eunson, J. & Chopra, A. K., Nov 2014, In: Applied Microbiology and Biotechnology. 98, 21, p. 8797-8807 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Space Flight
  • Weightlessness
  • Virulence
  • Salmonella typhimurium
  • Yersinia pestis
  27 Scopus citations

• Modulation of host immune defenses by aeromonas and yersinia species: Convergence on toxins secreted by various secretion systems

  Rosenzweig, J. A. & Chopra, A. K., 2013, In: Frontiers in Cellular and Infection Microbiology. 4, OCT, Article 70.

  Research output: Contribution to journal › Review article › peer-review

  • Aeromonas
  • Yersinia
  • Bacterial Secretion Systems
  • Immune System
  • Integration Host Factors
  17 Scopus citations

• Progress on plague vaccine development

  Rosenzweig, J. A., Jejelowo, O., Sha, J., Erova, T. E., Brackman, S. M., Kirtley, M. L., Van Lier, C. J. & Chopra, A. K., Jul 2011, In: Applied Microbiology and Biotechnology. 91, 2, p. 265-286 22 p.

  Research output: Contribution to journal › Review article › peer-review

  • Plague Vaccine
  • Yersinia pestis
  • Plague
  • Vaccines
  • Yersinia pseudotuberculosis
  29 Scopus citations

• The effect of low shear force on the virulence potential of Yersinia pestis: new aspects that space-like growth conditions and the final frontier can teach us about a formidable pathogen.

  Rosenzweig, J. A. & Chopra, A. K., 2012, In: Frontiers in Cellular and Infection Microbiology. 2, p. 107 1 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Yersinia pestis
  • Weightlessness
  • Virulence
  • Growth
  • Space Flight
  8 Scopus citations

• The exoribonuclease polynucleotide phosphorylase influences the virulence and stress responses of yersiniae and many other pathogens

  Rosenzweig, J. A. & Chopra, A. K., 2013, In: Frontiers in Cellular and Infection Microbiology. 4, NOV, Article 81.

  Research output: Contribution to journal › Review article › peer-review

  • Exoribonucleases
  • Polyribonucleotide Nucleotidyltransferase
  • Yersinia
  • Virulence
  • degradosome
  16 Scopus citations

• The future of plague vaccines: Hopes raised by a surrogate, live-attenuated recombinant vaccine candidate

  Rosenzweig, J. A. & Chopra, A. K., Jun 1 2012, In: Expert review of vaccines. 11, 6, p. 659-661 3 p.

  Research output: Contribution to journal › Review article › peer-review

  • Plague Vaccine
  • Yersinia pestis
  • Plague
  • Attenuated Vaccines
  • Synthetic Vaccines
  8 Scopus citations
• Comment/debate

  Erratum: Expression of concern: Aldose reductase mediates the lipopolysaccharide-induced release of inflammatory mediators in RAW264.7 murine macrophages (Journal of Biological Chemistry (2006) 281 (33019-33029))

  Ramana, K. V., Fadl, A. A., Tammali, R., Reddy, A. B. M., Chopra, A. K. & Srivastava, S. K., Feb 1 2019, In: Journal of Biological Chemistry. 294, 5, p. 1633 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Macrophages
  • Aldehyde Reductase
  • Lipopolysaccharides
• Article

  A bacteriophage T4 nanoparticle-based dual vaccine against anthrax and plague

  Tao, P., Mahalingam, M., Zhu, J., Moayeri, M., Sha, J., Lawrence, W. S., Leppla, S. H., Chopra, A. K. & Rao, V. B., Sep 1 2018, In: mBio. 9, 5, e01926-18.

  Research output: Contribution to journal › Article › peer-review

  • Plague Vaccine
  • Anthrax Vaccines
  • Anthrax
  • Bacteriophage T4
  • Plague
  16 Scopus citations

• A bivalent anthrax-plague vaccine that can protect against two Tier-1 bioterror pathogens, Bacillus anthracis and Yersinia pestis

  Tao, P., Mahalingam, M., Zhu, J., Moayeri, M., Kirtley, M. L., Fitts, E. C., Andersson, J. A., Lawrence, W. S., Leppla, S. H., Chopra, A. K. & Rao, V. B., Jun 26 2017, In: Frontiers in immunology. 8, JUN, 687.

  Research output: Contribution to journal › Article › peer-review

  • Plague Vaccine
  • Anthrax Vaccines
  • Yersinia pestis
  • Bacillus anthracis
  • Anthrax
  15 Scopus citations

• Actin cross-linking domain of Aeromonas hydrophila repeat in toxin A (RtxA) induces host cell rounding and apoptosis

  Suarez, G., Khajanchi, B. K., Sierra, J. C., Erova, T. E., Sha, J. & Chopra, A. K., Sep 15 2012, In: Gene. 506, 2, p. 369-376 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Actins
  • Apoptosis
  • Vibrio
  • Operon
  23 Scopus citations

• A non-invasive in vivo imaging system to study dissemination of bioluminescent Yersinia pestis CO92 in a mouse model of pneumonic plague

  Sha, J., Rosenzweig, J. A., Kirtley, M. L., van Lier, C. J., Fitts, E. C., Kozlova, E. V., Erova, T. E., Tiner, B. L. & Chopra, A. K., Feb 2013, In: Microbial Pathogenesis. 55, 1, p. 39-50 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Plague
  • Bacteria
  • Animals
  • Lethal Dose 50
  25 Scopus citations

• A prokaryotic-eukaryotic hybrid viral vector for delivery of large cargos of genes and proteins into human cells

  Zhu, J., Tao, P., Mahalingam, M., Sha, J., Kilgore, P., Chopra, A. K. & Rao, V., Aug 21 2019, In: Science Advances. 5, 8, eaax0064.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • viruses
  • genes
  • delivery
  • proteins
  • biotin
  2 Scopus citations

• Cethromycin-mediated protection against the plague pathogen Yersinia pestis in a rat model of infection and comparison with levofloxacin

  Rosenzweig, J. A., Brackman, S. M., Kirtley, M. L., Sha, J., Erova, T. E., Yeager, L. A., Peterson, J. W., Xu, Z. Q. & Chopra, A. K., Nov 2011, In: Antimicrobial agents and chemotherapy. 55, 11, p. 5034-5042 9 p.

  Research output: Contribution to journal › Article › peer-review

  • cethromycin
  • Yersinia pestis
  • Plague
  • Levofloxacin
  • Infection
  14 Scopus citations

• Characterization of Aeromonas hydrophila wound pathotypes by comparative genomic and functional analyses of virulence genes

  Grim, C. J., Kozlov, E. V., Sha, J., Fitts, E. C., van Lier, C. J., Kirtley, M. L., Joseph, S. J., Read, T. D., Burd, E. M., Tall, B. D., Joseph, S. W., Horneman, A. J., Chopra, A. K. & Shak, J. R., Mar 2013, In: mBio. 4, 2, e00064-13.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Genomics
  • Virulence
  • Wounds and Injuries
  • Genes
  44 Scopus citations

• Characterization of an actin-targeting ADP-ribosyltransferase from Aeromonas hydrophila

  Shniffer, A., Visschedyk, D. D., Ravulapalli, R., Suarez, G., Turgeon, Z. J., Petrie, A. A., Chopra, A. K. & Merrill, A. R., Oct 26 2012, In: Journal of Biological Chemistry. 287, 44, p. 37030-37041 12 p.

  Research output: Contribution to journal › Article › peer-review

  • ADP Ribose Transferases
  • Aeromonas hydrophila
  • Actins
  • Adenosine Diphosphate Ribose
  • Crystal structure
  12 Scopus citations

• Characterization of an F1 deletion mutant of Yersinia pestis CO92, pathogenic role of F1 antigen in bubonic and pneumonic plague, and evaluation of sensitivity and specificity of F1 antigen capture-based dipsticks

  Sha, J., Endsley, J. J., Kirtley, M. L., Foltz, S. M., Huante, M. B., Erova, T. E., Kozlova, E. V., Popov, V. L., Yeager, L. A., Zudina, I. V., Motin, V. L., Peterson, J. W., DeBord, K. L. & Chopra, A. K., May 2011, In: Journal of Clinical Microbiology. 49, 5, p. 1708-1715 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Plague
  • Sensitivity and Specificity
  • Antigens
  • Homologous Recombination
  26 Scopus citations

• Combating multidrug-resistant pathogens with host-directed nonantibiotic therapeutics

  Andersson, J. A., Sha, J., Kirtley, M. L., Reyes, E., Fitts, E. C., Dann, S. M. & Chopra, A. K., Jan 2018, In: Antimicrobial agents and chemotherapy. 62, 1, e01943.

  Research output: Contribution to journal › Article › peer-review

  • Plague
  • Pharmaceutical Preparations
  • Macrophages
  • Acinetobacter baumannii
  • Klebsiella pneumoniae
  8 Scopus citations

• Deletion of braun lipoprotein and plasminogen-activating protease-encoding genes attenuates Yersinia pestis in mouse models of bubonic and pneumonic plague

  Van Lier, C. J., Sha, J., Kirtley, M. L., Cao, A., Tiner, B. L., Erova, T. E., Cong, Y., Kozlova, E. V., Popov, V. L., Baze, W. B. & Chopra, A. K., 2014, In: Infection and immunity. 82, 6, p. 2485-2503 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Plague
  • Plasminogen
  • Lipoproteins
  • Peptide Hydrolases
  19 Scopus citations

• Deletion of the braun lipoprotein-encoding gene and altering the function of lipopolysaccharide attenuate the plague bacterium

  Sha, J., Kirtley, M. L., van Lier, C. J., Wang, S., Erova, T. E., Kozlova, E. V., Cao, A., Cong, Y., Fitts, E. C., Rosenzweig, J. A. & Chopra, A. K., Mar 2013, In: Infection and immunity. 81, 3, p. 815-828 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Plague
  • Lipoproteins
  • Lipopolysaccharides
  • Yersinia pestis
  • Bacteria
  20 Scopus citations

• Dissemination of non-typhoidal Salmonella during Plasmodium chabaudi infection affects anti-malarial immunity

  Alamer, E., Carpio, V. H., Ibitokou, S. A., Kirtley, M. L., Phoenix, I. R., Opata, M. M., Wilson, K. D., Cong, Y., Dann, S. M., Chopra, A. K. & Stephens, R., Jul 1 2019, In: Parasitology research. 118, 7, p. 2277-2285 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Plasmodium chabaudi
  • antimalarials
  • Antimalarials
  • Salmonella
  • Malaria
  3 Scopus citations

• DNA adenine methyltransferase (Dam) controls the expression of the cytotoxic enterotoxin (act) gene of Aeromonas hydrophila via tRNA modifying enzyme-glucose-inhibited division protein (GidA)

  Erova, T. E., Kosykh, V. G., Sha, J. & Chopra, A. K., May 1 2012, In: Gene. 498, 2, p. 280-287 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Enterotoxins
  • Adenine
  • Methyltransferases
  • Transfer RNA
  12 Scopus citations

• Evaluation of protective potential of Yersinia pestis outer membrane protein antigens as possible candidates for a new-generation recombinant plague vaccine

  Erova, T. E., Rosenzweig, J. A., Sha, J., Suarez, G., Sierra, J. C., Kirtley, M. L., Van Lier, C. J., Telepnev, M. V., Motin, V. L. & Chopra, A. K., Feb 2013, In: Clinical and Vaccine Immunology. 20, 2, p. 227-238 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Synthetic Vaccines
  • Plague Vaccine
  • Yersinia pestis
  • Plague
  • Rats
  20 Scopus citations

• Evaluation of the roles played by Hcp and VgrG type 6 secretion system effectors in aeromonas hydrophila SSU pathogenesis

  Sha, J., Rosenzweig, J. A., Kozlova, E. V., Wang, S., Erova, T. E., Kirtley, M. L., van Lier, C. J. & Chopra, A. K., Jun 1 2013, In: Microbiology (United Kingdom). 159, PART 6, p. 1120-1135 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Type VI Secretion Systems
  • Aeromonas hydrophila
  • Peptide Hydrolases
  • Biofilms
  • Virulence
  28 Scopus citations

• Functional genomic characterization of virulence factors from necrotizing fasciitis-causing strains of Aeromonas hydrophila

  Grim, C. J., Kozlova, E. V., Ponnusamy, D., Fitts, E. C., Sha, J., Kirtley, M. L., van Lier, C. J., Tiner, B. L., Erova, T. E., Joseph, S. J., Read, T. D., Shak, J. R., Joseph, S. W., Singletary, E., Felland, T., Baze, W. B., Horneman, A. J. & Chopra, A. K., 2014, In: Applied and Environmental Microbiology. 80, 14, p. 4162-4183 22 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • virulence
  • Necrotizing Fasciitis
  • Aeromonas
  • virulent strains
  37 Scopus citations

• Identification of new virulence factors and vaccine candidates for Yersinia pestis

  Andersson, J. A., Sha, J., Erova, T. E., Fitts, E. C., Ponnusamy, D., Kozlova, E. V., Kirtley, M. L. & Chopra, A. K., Oct 17 2017, In: Frontiers in Cellular and Infection Microbiology. 7, OCT, 448.

  Research output: Contribution to journal › Article › peer-review

  • Yersinia pestis
  • Plague
  • Virulence Factors
  • Mutagenesis
  • Vaccines
  14 Scopus citations

• Immunomodulatory and protective Roles of quorum-sensing signaling molecules N-Acyl homoserine lactones during infection of mice with Aeromonas hydrophila

  Khajanchi, B. K., Kirtley, M. L., Brackman, S. M. & Chopra, A. K., Jul 2011, In: Infection and immunity. 79, 7, p. 2646-2657 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Acyl-Butyrolactones
  • Aeromonas hydrophila
  • Quorum Sensing
  • Infection
  • Animals
  32 Scopus citations

• Impact of QseBC system in c-di-GMP-dependent quorum sensing regulatory network in a clinical isolate SSU of Aeromonas hydrophila

  Kozlova, E. V., Khajanchi, B. K., Popov, V. L., Wen, J. & Chopra, A. K., Sep 2012, In: Microbial Pathogenesis. 53, 3-4, p. 115-124 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Quorum Sensing
  • Cyclic GMP
  • Biofilms
  • Virulence
  20 Scopus citations

• In vitro and in vivo delivery of genes and proteins using the bacteriophage T4 DNA packaging machine

  Tao, P., Mahalingam, M., Marasa, B. S., Zhang, Z., Chopra, A. K. & Rao, V. B., Apr 9 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 15, p. 5846-5851 6 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Packaging
  • Bacteriophage T4
  • Capsid Proteins
  • Head
  • Plague Vaccine
  51 Scopus citations

• Mutated and Bacteriophage T4 Nanoparticle Arrayed F1-V Immunogens from Yersinia pestis as Next Generation Plague Vaccines

  Tao, P., Mahalingam, M., Kirtley, M. L., van Lier, C. J., Sha, J., Yeager, L. A., Chopra, A. K. & Rao, V. B., Jul 2013, In: PLoS pathogens. 9, 7, e1003495.

  Research output: Contribution to journal › Article › peer-review

  • Plague Vaccine
  • Yersinia pestis
  • Bacteriophage T4
  • Plague
  • Nanoparticles
  29 Scopus citations

• Phospholipase A₂-activating protein is associated with a novel form of leukoencephalopathy

  Falik Zaccai, T. C., Savitzki, D., Zivony-Elboum, Y., Vilboux, T., Fitts, E. C., Shoval, Y., Kalfon, L., Samra, N., Keren, Z., Gross, B., Chasnyk, N., Straussberg, R., Mullikin, J. C., Teer, J. K., Geiger, D., Kornitzer, D., Bitterman-Deutsch, O., Samson, A. O., Wakamiya, M., Peterson, J. W. & 7 others, Kirtley, M. L., Pinchuk, I. V., Baze, W. B., Gahl, W. A., Kleta, R., Anikster, Y. & Chopra, A. K., Feb 2017, In: Brain. 140, 2, p. 370-386 17 p.

  Research output: Contribution to journal › Article › peer-review

  • phospholipase A2-activating protein
  • Leukoencephalopathies
  • Protein
  • Dinoprostone
  • Phenotype
  9 Scopus citations

• Protection against inhalation anthrax by immunization with Salmonella enterica serovar Typhi Ty21a stably producing protective antigen of Bacillus anthracis

  Sim, B. K. L., Li, M., Osorio, M., Wu, Y., Wai, T. T., Peterson, J. W., James, E. R., Chakravarty, S., Gao, L., Xu, R., Kc, N., Stafford, R. E., Lawrence, W. S., Yeager, L. A., Peel, J. E., Sivasubramani, S. K., Chopra, A. K., Filippova, S. & Hoffman, S. L., Dec 1 2017, In: npj Vaccines. 2, 1, 17.

  Research output: Contribution to journal › Article › peer-review

  • Inhalation anthrax
  • anthrax toxin
  • Salmonella typhi
  • Anthrax Vaccines
  • Bacillus anthracis
  7 Scopus citations

• Quorum sensing and c-di-GMP-dependent alterations in gene transcripts and virulence-associated phenotypes in a clinical isolate of Aeromonas hydrophila

  Kozlova, E. V., Khajanchi, B. K., Sha, J. & Chopra, A. K., May 2011, In: Microbial Pathogenesis. 50, 5, p. 213-223 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Quorum Sensing
  • Biofilms
  • Virulence
  • Phenotype
  26 Scopus citations

• T6SS and ExoA of flesh-eating Aeromonas hydrophila in peritonitis and necrotizing fasciitis during mono- And polymicrobial infections

  Fernández-Bravo, A., Kilgore, P. B., Andersson, J. A., Blears, E., Figueras, M. J., Hasan, N. A., Colwell, R. R., Sha, J. & Chopra, A. K., Nov 26 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 48, p. 24084-24092 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Type VI Secretion Systems
  • Aeromonas hydrophila
  • Exotoxins
  • Necrotizing Fasciitis
  • Peritonitis
  5 Scopus citations

• The effects of modeled microgravity on growth kinetics, antibiotic susceptibility, cold growth, and the virulence potential of a yersinia pestis ymoa-deficient mutant and its isogenic parental strain

  Lawal, A., Kirtley, M. L., Van Lier, C. J., Erova, T. E., Kozlova, E. V., Sha, J., Chopra, A. K. & Rosenzweig, J. A., Sep 1 2013, In: Astrobiology. 13, 9, p. 821-832 12 p.

  Research output: Contribution to journal › Article › peer-review

  • clinorotation
  • virulence
  • Yersinia pestis
  • antibiotics
  • Weightlessness
  13 Scopus citations

• The two-component QseBC signalling system regulates in vitro and in vivo virulence of Aeromonas hydrophila

  Khajanchi, B. K., Kozlova, E. V., Sha, J., Popov, V. L. & Chopra, A. K., Jan 2012, In: Microbiology. 158, 1, p. 259-271 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Aeromonas hydrophila
  • Quorum Sensing
  • Virulence
  • N-(3-oxohexanoyl)-3-aminodihydro-2(3H)-furanone
  • N-octanoylhomoserine lactone
  44 Scopus citations