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• Review article

  Bacterial manipulation of wnt signaling: A host-pathogen tug-of-wnt

  Rogan, M. R., Patterson, L. L., Wang, J. Y. & McBride, J. W., 2019, In: Frontiers in immunology. 10, OCT, 2390.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Wnt Signaling Pathway
  • Bacterial Infections
  • Viral Tropism
  • Organogenesis
  • Survival
  4 Scopus citations

• Engineering of obligate intracellular bacteria: Progress, challenges and paradigms

  McClure, E. E., Chávez, A. S. O., Shaw, D. K., Carlyon, J. A., Ganta, R. R., Noh, S. M., Wood, D. O., Bavoil, P. M., Brayton, K. A., Martinez, J. J., McBride, J. W., Valdivia, R. H., Munderloh, U. G. & Pedra, J. H. F., Sep 1 2017, In: Nature Reviews Microbiology. 15, 9, p. 544-558 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Bacteria
  • Coxiella
  • Anaplasma
  • Ehrlichia
  • Rickettsia
  43 Scopus citations

• Hacker within! Ehrlichia chaffeensis effector driven phagocyte reprogramming strategy

  Lina, T. T., Farris, T., Luo, T., Mitra, S., Zhu, B. & McBride, J. W., May 31 2016, In: Frontiers in Cellular and Infection Microbiology. 6, MAY, 58.

  Research output: Contribution to journal › Review article › peer-review

  • Ehrlichia chaffeensis
  • Phagocytes
  • Ehrlichia
  • Ehrlichiosis
  • Ankyrin Repeat
  18 Scopus citations

• Tick-Borne Emerging Infections: Ehrlichiosis and Anaplasmosis

  Ismail, N. & McBride, J. W., Jun 2017, In: Clinics in Laboratory Medicine. 37, 2, p. 317-340 24 p.

  Research output: Contribution to journal › Review article › peer-review

  • Anaplasmosis
  • Ehrlichiosis
  • Tick-Borne Diseases
  • Anaplasma
  • Macrophages
  61 Scopus citations
• Editorial

  Editorial: Wnt Signaling in Immune Cell Regulation During Microbial Infection and Cancer

  Blumenthal, A., Martin-Orozco, E., McBride, J. W., Carson, D. A. & Sen, M., Jun 5 2020, In: Frontiers in immunology. 11, 1133.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access
• Conference contribution

  Eukaryote interactions and tandem and ankyrin repeat effectors

  McBride, J. W., Wakeel, A. & Kuriakose, J. A., 2011, Ehrlichia.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
• Chapter

  Human ehrlichioses and rickettsioses in Cameroon

  Ndip, LN., Ndip, R., Walker, D. H. & McBride, J. W., 2012, Current Topics in Tropical Medicine. p. 25-42

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
• Article

  Activation of ASC Inflammasome Driven by Toll-Like Receptor 4 Contributes to Host Immunity against Rickettsial Infection

  Rumfield, C., Hyseni, I., McBride, J. W., Walker, D. H. & Fang, R., Mar 23 2020, In: Infection and immunity. 88, 4

  Research output: Contribution to journal › Article › peer-review

  • Inflammasomes
  • Toll-Like Receptor 4
  • Interleukin-1
  • Immunity
  • Macrophages
  1 Scopus citations

• A West Nile virus NS4B-P38G mutant strain induces cell intrinsic innate cytokine responses in human monocytic and macrophage cells

  Xie, G., Luo, H., Tian, B., Mann, B., Bao, X., McBride, J., Tesh, R., Barrett, A. D. & Wang, T., Feb 11 2015, In: Vaccine. 33, 7, p. 869-878 10 p.

  Research output: Contribution to journal › Article › peer-review

  • West Nile virus
  • cytokines
  • macrophages
  • Macrophages
  • Cytokines
  4 Scopus citations

• Detecção de patógenos rickettsiais transmitidos por carrapatos em cães naturalmente infectados e carrapatos associados a cães em medellin, colômbia

  Arroyave, E., Cornwell, E. R., McBride, J. W., Díaz, C. A., Labruna, M. B. & Rodas, J. D., 2020, In: Revista Brasileira de Parasitologia Veterinaria. 29, 3, p. 1-12 12 p., e005320.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Colombia
  • Ticks
  • ticks
  • dogs
  • Dogs

• Detection of genotype-specific Ehrlichia canis exposure in Brazilian dogs by TRP36 peptide ELISA

  Aguiar, D. M., Zhang, X., Braga, I. A., Taques, I. I. G. G. & McBride, J. W., Feb 2016, In: Ticks and Tick-borne Diseases. 7, 1, p. 142-145 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia canis
  • enzyme-linked immunosorbent assay
  • dogs
  • Genotype
  • Dogs
  10 Scopus citations

• Ehrlichia canis TRP36 diversity in naturally infected-dogs from an urban area of Colombia

  Arroyave, E., Rodas-González, J. D., Zhang, X., Labruna, M. B., González, M. S., Fernández-Silva, J. A. & McBride, J. W., May 2020, In: Ticks and Tick-borne Diseases. 11, 3, 101367.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia canis
  • Colombia
  • urban areas
  • dogs
  • Genotype
  3 Scopus citations

• Ehrlichia chaffeensis and E. canis hypothetical protein immunoanalysis reveals small secreted immunodominant proteins and conformation-dependent antibody epitopes

  Luo, T., Patel, J. G., Zhang, X., Walker, D. H. & McBride, J. W., Dec 1 2020, In: npj Vaccines. 5, 1, 85.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ehrlichia chaffeensis
  • Protein Conformation
  • Epitopes
  • Antibodies
  • Proteins

• Ehrlichia chaffeensis exploits canonical and noncanonical host Wnt signaling pathways to stimulate phagocytosis and promote intracellular survival

  Luo, T., Dunphy, P. S., Lina, T. T. & McBride, J. W., Mar 1 2016, In: Infection and immunity. 84, 3, p. 686-700 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Wnt Signaling Pathway
  • Tandem Repeat Sequences
  • Phagocytosis
  • Catenins
  27 Scopus citations

• Ehrlichia chaffeensis outer membrane protein 1-specific human antibody-mediated immunity is defined by intracellular TRIM21-dependent innate immune activation and extracellular neutralization

  Velayutham, T. S., Kumar, S., Zhang, X., Kose, N., Walker, D. H., Winslow, G., Crowe, J. E. & McBride, J. W., Dec 1 2019, In: Infection and immunity. 87, 12, e00383-19.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ehrlichia chaffeensis
  • Ehrlichia
  • Membrane Proteins
  • Immunity
  • Autophagy
  4 Scopus citations

• Ehrlichia chaffeensis tandem repeat effector targets differentially influence infection

  Luo, T., Dunphy, P. S. & McBride, J. W., May 12 2017, In: Frontiers in Cellular and Infection Microbiology. 7, MAY, 178.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Tandem Repeat Sequences
  • Infection
  • Proteins
  • Morula
  7 Scopus citations

• Ehrlichia chaffeensis tandem repeat proteins and Ank200 are type 1 secretion system substrates related to the repeats-in-toxin exoprotein family

  Wakeel, A., den Dulk-Ras, A., Hooykaas, P. J. J. & McBride, J. W., 2011, In: Frontiers in Cellular and Infection Microbiology. 1, p. 22 1 p.

  Research output: Contribution to journal › Article › peer-review

  • Type I Secretion Systems
  • Ehrlichia chaffeensis
  • Tandem Repeat Sequences
  • Ehrlichia
  • Host-Pathogen Interactions
  38 Scopus citations

• Ehrlichia chaffeensis transcriptome in mammalian and arthropod hosts reveals differential gene expression and post transcriptional regulation

  Kuriakose, J. A., Miyashiro, S., Luo, T., Zhu, B. & McBride, J. W., 2011, In: PloS one. 6, 9, e24136.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Arthropods
  • Ticks
  • Gene expression
  • Transcriptome
  38 Scopus citations

• Ehrlichia chaffeensis TRP120 activates canonical notch signaling to downregulate TLR2/4 expression and promote intracellular survival

  Lina, T. T., Dunphy, P. S., Luo, T. & McBride, J. W., Jul 1 2016, In: mBio. 7, 4, e00672-16.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Toll-Like Receptor 2
  • Toll-Like Receptor 4
  • Down-Regulation
  • ADAM17 Protein
  22 Scopus citations

• Ehrlichia chaffeensis TRP120 binds a G+C-rich motif in host cell DNA and exhibits eukaryotic transcriptional activator function

  Zhu, B., Kuriakose, J. A., Luo, T., Ballesteros, E., Gupta, S., Fofanov, Y. & McBride, J. W., Nov 2011, In: Infection and immunity. 79, 11, p. 4370-4381 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Activator Appliances
  • DNA
  • Genes
  • Tandem Repeat Sequences
  37 Scopus citations

• Ehrlichia chaffeensis TRP120 interacts with a diverse array of eukaryotic proteins involved in transcription, signaling, and cytoskeleton organization

  Luo, T., Kuriakose, J. A., Zhu, B., Wakeel, A. & McBride, J. W., Nov 2011, In: Infection and immunity. 79, 11, p. 4382-4391 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Tandem Repeat Sequences
  • Protein Array Analysis
  • Cytoskeleton
  • Proteins
  38 Scopus citations

• Ehrlichia chaffeensis TRP120-mediated ubiquitination and proteasomal degradation of tumor suppressor FBW7 increases oncoprotein stability and promotes infection

  Wang, J. Y., Zhu, B., Patterson, L. N. L., Rogan, M. R., Kibler, C. E. & McBride, J. W., Apr 1 2020, In: PLoS pathogens. 16, 4, e1008541.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ehrlichia chaffeensis
  • Oncogene Proteins
  • Ubiquitination
  • Ubiquitin-Protein Ligases
  • Ehrlichiosis
  2 Scopus citations

• Ehrlichia chaffeensis TRP120 moonlights as a HECT E3 ligase involved in selfand host ubiquitination to influence protein interactions and stability for intracellular survival

  Zhu, B., Das, S., Mitra, S., Farris, T. R. & McBride, J. W., Sep 1 2017, In: Infection and immunity. 85, 9, e00290-17.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Protein Stability
  • Ubiquitin-Protein Ligases
  • Ubiquitination
  • Ubiquitin
  10 Scopus citations

• Ehrlichia chaffeensis TRP32 interacts with host cell targets that influence intracellular survival

  Luo, T. & McBride, J. W., Jul 2012, In: Infection and immunity. 80, 7, p. 2297-2306 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Morula
  • Survival
  • Deleted in Azoospermia 1 Protein
  • Translational Peptide Chain Elongation
  32 Scopus citations

• Ehrlichia chaffeensis TRP32 is a nucleomodulin that directly regulates expression of host genes governing differentiation and proliferation

  Farris, T. R., Dunphy, P. S., Zhu, B., Kibler, C. E. & McBride, J. W., 2016, In: Infection and immunity. 84, 11, p. 3182-3194 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Gene Expression
  • trityrosine
  • Genes
  • MicroRNAs
  14 Scopus citations

• Ehrlichia moonlighting effectors and interkingdom interactions with the mononuclear phagocyte

  Dunphy, P. S., Luo, T. & McBride, J. W., Dec 2013, In: Microbes and Infection. 15, 14-15, p. 1005-1016 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Ehrlichia
  • Tandem Repeat Sequences
  • Phagocytes
  • Gram-Negative Bacteria
  19 Scopus citations

• Genetic diversity of Ehrlichia canis in Brazil

  Aguiar, D. M., Zhang, X., Melo, A. L. T., Pacheco, T. A., Meneses, A. M. C., Zanutto, M. S., Horta, M. C., Santarém, V. A., Camargo, L. M. A., McBride, J. W. & Labruna, M. B., 2013, In: Veterinary Microbiology. 164, 3-4, p. 315-321 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia canis
  • Genetic Variation
  • Brazil
  • Genotype
  • genetic variation
  34 Scopus citations

• Molecular and cellular pathobiology of Ehrlichia infection: Targets for new therapeutics and immunomodulation strategies

  McBride, J. W. & Walker, D. H., Jan 2011, In: Expert reviews in molecular medicine. 13, e3.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Immunomodulation
  • Ehrlichia
  • Host-Pathogen Interactions
  • Rickettsiales
  40 Scopus citations

• Molecular basis of antibody mediated immunity against Ehrlichia chaffeensis involves species-specific linear epitopes in tandem repeat proteins

  Kuriakose, J. A., Zhang, X., Luo, T. & McBride, J. W., Oct 2012, In: Microbes and Infection. 14, 12, p. 1054-1063 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Tandem Repeat Sequences
  • Epitopes
  • Immunity
  • Antibodies
  22 Scopus citations

• Rapid identification of ubiquitination and SUMOylation target sites by microfluidic peptide array

  Zhu, B., Farris, T. R., Milligan, S. L., Chen, H., Zhu, R., Hong, A., Zhou, X., Gao, X. & McBride, J. W., Mar 1 2016, In: Biochemistry and Biophysics Reports. 5, p. 430-438 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Sumoylation
  • Microfluidics
  • Ubiquitination
  • Ubiquitin
  • Identification (control systems)
  10 Scopus citations

• Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis

  Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In: Vaccine. 31, 50, p. 5960-5967 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • ehrlichiosis
  • Ehrlichiosis
  • Tandem Repeat Sequences
  • Ehrlichia chaffeensis
  4 Scopus citations

• The Prostaglandin E₂-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation

  Wang, X., Shaw, D. K., Hammond, H. L., Sutterwala, F. S., Rayamajhi, M., Shirey, K. A., Perkins, D. J., Bonventre, J. V., Velayutham, T. S., Evans, S. M., Rodino, K. G., VieBrock, L., Scanlon, K. M., Carbonetti, N. H., Carlyon, J. A., Miao, E. A., McBride, J. W., Kotsyfakis, M. & Pedra, J. H. F., Aug 2016, In: PLoS pathogens. 12, 8, e1005803.

  Research output: Contribution to journal › Article › peer-review

  • Anaplasma phagocytophilum
  • Inflammasomes
  • Dinoprostone
  • Anaplasmosis
  • Interleukin-18
  15 Scopus citations

• Tyrosine-phosphorylated Ehrlichia chaffeensis and Ehrlichia canis tandem repeat orthologs contain a major continuous cross-reactive antibody epitope in lysine-rich repeats

  McBride, J. W., Zhang, X., Wakeel, A. & Kuriakose, J. A., Aug 2011, In: Infection and immunity. 79, 8, p. 3178-3187 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Ehrlichia canis
  • Tandem Repeat Sequences
  • Lysine
  • Tyrosine
  17 Scopus citations