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Short survey
Flavivirus NS5 prevents the InSTATement of IFN
Shi, P. Y., Sep 10 2014, In: Cell Host and Microbe. 16, 3, p. 269-271 3 p.Research output: Contribution to journal › Short survey › peer-review
10 Scopus citations -
Therapeutics for Neglected Infectious Diseases: Progress and Challenge
Shi, P. Y., Smith, P. W. & Diagana, T. T., Jan 8 2015, In: ACS Infectious Diseases. 1, 1, p. 76-78 3 p.Research output: Contribution to journal › Short survey › peer-review
7 Scopus citations -
Unraveling a flavivirus enigma
Shi, P. Y., Jan 1 2014, In: Science. 343, 6173, p. 849-850 2 p.Research output: Contribution to journal › Short survey › peer-review
9 Scopus citations -
Review article
Antagonism of Type i Interferon by Severe Acute Respiratory Syndrome Coronavirus 2
Xia, H. & Shi, P. Y., Dec 2020, In: Journal of Interferon and Cytokine Research. 40, 12, p. 543-548 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Anti-infectives: Can cellular screening deliver?
Keller, T. H., Shi, P. Y. & Wang, Q. Y., Aug 2011, In: Current Opinion in Chemical Biology. 15, 4, p. 529-533 5 p.Research output: Contribution to journal › Review article › peer-review
22 Scopus citations -
Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential
Xu, J., Shi, P. Y., Li, H. & Zhou, J., May 8 2020, In: ACS Infectious Diseases. 6, 5, p. 909-915 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access71 Scopus citations -
Did Zika Virus Mutate to Cause Severe Outbreaks?
Rossi, S. L., Ebel, G. D., Shan, C., Shi, P. Y. & Vasilakis, N., Oct 2018, In: Trends in Microbiology. 26, 10, p. 877-885 9 p.Research output: Contribution to journal › Review article › peer-review
12 Scopus citations -
Flavivirus RNA methylation
Dong, H., Fink, K., Züst, R., Lim, S. P., Qin, C. F. & Shi, P. Y., 2014, In: Journal of General Virology. 95, PART 4, p. 763-778 16 p.Research output: Contribution to journal › Review article › peer-review
66 Scopus citations -
Live attenuated vaccine: The first clinically approved dengue vaccine?
Fink, K. & Shi, P. Y., Feb 1 2014, In: Expert review of vaccines. 13, 2, p. 185-188 4 p.Research output: Contribution to journal › Review article › peer-review
14 Scopus citations -
Polymerases of hepatitis C viruses and flaviviruses: Structural and mechanistic insights and drug development
Caillet-Saguy, C., Lim, S. P., Shi, P. Y., Lescar, J. & Bressanelli, S., May 2014, In: Antiviral research. 105, 1, p. 8-16 9 p.Research output: Contribution to journal › Review article › peer-review
38 Scopus citations -
Potential Mechanisms for Enhanced Zika Epidemic and Disease
Xia, H., Xie, X., Shan, C. & Shi, P. Y., May 11 2018, In: ACS Infectious Diseases. 4, 5, p. 656-659 4 p.Research output: Contribution to journal › Review article › peer-review
5 Scopus citations -
Reserve genetic approaches for the development of Zika vaccines and therapeutics
Fontes-Garfias, C. R., Baker, C. K. & Shi, P. Y., Oct 2020, In: Current Opinion in Virology. 44, p. 7-15 9 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
Small Molecules and Antibodies for Zika Therapy
Xie, X., Zou, J., Shan, C. & Shi, P. Y., 2017, In: Journal of Infectious Diseases. 216, p. S945-S950Research output: Contribution to journal › Review article › peer-review
15 Scopus citations -
Structural biology of dengue virus enzymes: Towards rational design of therapeutics
Noble, C. G. & Shi, P. Y., Nov 1 2012, In: Antiviral research. 96, 2, p. 115-126 12 p.Research output: Contribution to journal › Review article › peer-review
78 Scopus citations -
Targeting dengue virus NS4B protein for drug discovery
Xie, X., Zou, J., Wang, Q. Y. & Shi, P. Y., Jun 2015, In: Antiviral research. 118, p. 39-45 7 p., 3603.Research output: Contribution to journal › Review article › peer-review
44 Scopus citations -
The search for nucleoside/nucleotide analog inhibitors of dengue virus
Chen, Y. L., Yokokawa, F. & Shi, P. Y., Aug 10 2015, In: Antiviral research. 122, p. 12-19 8 p., 3670.Research output: Contribution to journal › Review article › peer-review
44 Scopus citations -
Type I and Type III interferons restrict SARS-CoV-2 infection of human airway epithelial cultures
Vanderheiden, A., Ralfs, P., Chirkova, T., Upadhyay, A. A., Zimmerman, M. G., Bedoya, S., Aoued, H., Tharp, G. M., Pellegrini, K. L., Manfredi, C., Sorscher, E., Mainou, B., Lobby, J. L., Kohlmeier, J. E., Lowen, A. C., Shi, P. Y., Menachery, V. D., Anderson, L. J., Grakoui, A., Bosinger, S. E. & 1 others, , Oct 2020, In: Journal of virology. 94, 19, e00985-20.Research output: Contribution to journal › Review article › peer-review
Open Access19 Scopus citations -
Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network
Aliota, M. T., Bassit, L., Bradrick, S. S., Cox, B., Garcia-Blanco, M. A., Gavegnano, C., Friedrich, T. C., Golos, T. G., Griffin, D. E., Haddow, A. D., Kallas, E. G., Kitron, U., Lecuit, M., Magnani, D. M., Marrs, C., Mercer, N., McSweegan, E., Ng, L. F. P., O'Connor, D. H., Osorio, J. E. & 11 others, , Aug 2017, In: Antiviral research. 144, p. 223-246 24 p.Research output: Contribution to journal › Review article › peer-review
67 Scopus citations -
Zika Virus Vaccine: Progress and Challenges
Shan, C., Xie, X. & Shi, P. Y., Jul 11 2018, In: Cell Host and Microbe. 24, 1, p. 12-17 6 p.Research output: Contribution to journal › Review article › peer-review
36 Scopus citations -
Letter
A single residue in the αb helix of the e protein is critical for Zika virus thermostability correspondence
Xie, D. Y., Liu, Z. Y., Nian, Q. G., Zhu, L., Wang, N., Deng, Y. Q., Zhao, H., Ji, X., Li, X. F., Wang, X., Shi, P. Y. & Qin, C. F., Dec 1 2018, In: Emerging Microbes and Infections. 7, 1, 0006.Research output: Contribution to journal › Letter › peer-review
3 Scopus citations -
Drug discovery for the developing world: Progress at the Novartis Institute for Tropical Diseases
Jones, C. L., Yeung, B. K. S., Manjunatha, U., Shi, P. Y., Bodenreider, C. & Diagana, T. T., Jun 3 2015, In: Nature Reviews Drug Discovery. 14, 6, p. 442-444 3 p.Research output: Contribution to journal › Letter › peer-review
4 Scopus citations -
Comment/debate
Adulthood Sequelae of Congenital Zika Virus Infection in Mice
Zou, J. & Shi, P. Y., Jun 2017, In: EBioMedicine. 20, p. 11-12 2 p.Research output: Contribution to journal › Comment/debate › peer-review
3 Scopus citations -
Corrigendum to "Population variation of West Nile virus confers a host-specific fitness benefit in mosquitoes" [Virology 404 (2010) 89-95]
Fitzpatrick, K. A., Deardorff, E. R., Pesko, K., Brackney, D. E., Zhang, B., Bedrick, E., Shi, P. Y. & Ebel, G. D., Feb 20 2011, In: Virology. 410, 2, p. 437 1 p.Research output: Contribution to journal › Comment/debate › peer-review
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Erratum: Zika virus has oncolytic activity against glioblastoma stem cells [The Journal of Experimental Medicine, 214, 10, (2017)] DOI: 10.1084/jem.20171093
Zhu, Z., Gorman, M. J., McKenzie, L. D., Chai, J. N., Hubert, C. G., Prager, B. C., Fernandez, E., Richner, J. M., Zhang, R., Shan, C., Tycksen, E., Wang, X., Shi, P. Y., Diamond, M. S., Rich, J. N. & Chheda, M. G., 2017, In: Journal of Experimental Medicine. 214, 10, p. 3145 1 p.Research output: Contribution to journal › Comment/debate › peer-review
6 Scopus citations -
Erratum to: Targeting vesicle size (Nature Materials, (2018), 17, 11, (955-956), 10.1038/s41563-018-0200-8)
Fei, Z. & Shi, P. Y., Dec 1 2018, In: Nature Materials. 17, 12, p. 1164 1 p.Research output: Contribution to journal › Comment/debate › peer-review
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Targeting vesicle size
Zou, J. & Shi, P. Y., Nov 1 2018, In: Nature Materials. 17, 11, p. 955-956 2 p.Research output: Contribution to journal › Comment/debate › peer-review
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Chapter
Dengue drug discovery
Shi, P. Y., Yin, Z., Nilar, S. & Keller, T. H., Oct 31 2011, Third World Diseases. Elliot, R. (ed.). p. 243-276 34 p. (Topics in Medicinal Chemistry; vol. 7).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Discovery of potent non-nucleoside inhibitors of dengue viral RNA-dependent rna polymerase from fragment screening and structure-guided design
Lim, S. P., Noble, C. G., Nilar, S., Shi, P. Y. & Yokokawa, F., 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 187-198 12 p. (Advances in Experimental Medicine and Biology; vol. 1062).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Reverse genetics of Zika virus
Shan, C., Xie, X. & Shi, P-Y., 2017, Methods in Molecular Biology. Humana Press Inc., Vol. 1602. p. 47-58 12 p. (Methods in Molecular Biology; vol. 1602).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Article
2′-O methylation of internal adenosine by flavivirus NS5 methyltransferase
Dong, H., Chang, D. C., Hua, M. H. C., Lim, S. P., Chionh, Y. H., Hia, F., Lee, Y. H., Kukkaro, P., Lok, S. M., Dedon, P. C. & Shi, P. Y., Apr 2012, In: PLoS pathogens. 8, 4, e1002642.Research output: Contribution to journal › Article › peer-review
85 Scopus citations -
A cDNA Clone-Launched Platform for High-Yield Production of Inactivated Zika Vaccine
Yang, Y., Shan, C., Zou, J., Muruato, A. E., Bruno, D. N., de Almeida Medeiros Daniele, B., Vasconcelos, P. F. C., Rossi, S. L., Weaver, S. C., Xie, X. & Shi, P. Y., Mar 1 2017, In: EBioMedicine. 17, p. 145-156 12 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
A cocrystal structure of dengue capsid protein in complex of inhibitor
Xia, H., Xie, X., Zou, J., Noble, C. G., Russell, W. K., Holthauzen, L. M. F., Choi, K. H., White, M. A. & Shi, P. Y., Jul 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 30, p. 17992-18001 10 p.Research output: Contribution to journal › Article › peer-review
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A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication
Zhao, Y., Soh, T. S., Zheng, J., Chan, K. W. K., Phoo, W. W., Lee, C. C., Tay, M. Y. F., Swaminathan, K., Cornvik, T. C., Lim, S. P., Shi, P. Y., Lescar, J., Vasudevan, S. G. & Luo, D., Mar 1 2015, In: PLoS pathogens. 11, 3, p. 1-27 27 p., e1004682.Research output: Contribution to journal › Article › peer-review
107 Scopus citations -
Activation of peripheral blood mononuclear cells by dengue virus infection depotentiates balapiravir
Chen, Y. L., Ghafar, N. A., Karuna, R., Fu, Y., Lim, S. P., Schul, W., Gu, F., Herve, M., Yokohama, F., Wang, G., Cerny, D., Fink, K., Blasco, F. & Shi, P. Y., Feb 2014, In: Journal of virology. 88, 3, p. 1740-1747 8 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
A fluorescence-based alkaline phosphatase-coupled polymerase assay for identification of inhibitors of dengue virus RNA-Dependent RNA polymerase
Niyomrattanakit, P., Abas, S. N., Lim, C. C., Beer, D., Shi, P. Y. & Chen, Y. L., Feb 2011, In: Journal of Biomolecular Screening. 16, 2, p. 201-210 10 p.Research output: Contribution to journal › Article › peer-review
39 Scopus citations -
A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation
Muruato, A. E., Fontes-Garfias, C. R., Ren, P., Garcia-Blanco, M. A., Menachery, V. D., Xie, X. & Shi, P. Y., Dec 1 2020, In: Nature communications. 11, 1, 4059.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models
Shan, C., Muruato, A. E., Nunes, B. T. D., Luo, H., Xie, X., Medeiros, D. B. A., Wakamiya, M., Tesh, R. B., Barrett, A. D., Wang, T., Weaver, S. C., Vasconcelos, P. F. C., Rossi, S. L. & Shi, P. Y., Jun 1 2017, In: Nature Medicine. 23, 6, p. 763-767 5 p.Research output: Contribution to journal › Article › peer-review
159 Scopus citations -
A Multiplex Microsphere Immunoassay for Zika Virus Diagnosis
Wong, S. J., Furuya, A., Zou, J., Xie, X., Dupuis, A. P., Kramer, L. D. & Shi, P. Y., Feb 1 2017, In: EBioMedicine. 16, p. 136-140 5 p.Research output: Contribution to journal › Article › peer-review
58 Scopus citations -
A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19
Xie, X., Muruato, A. E., Zhang, X., Lokugamage, K. G., Fontes-Garfias, C. R., Zou, J., Liu, J., Ren, P., Balakrishnan, M., Cihlar, T., Tseng, C. T. K., Makino, S., Menachery, V. D., Bilello, J. P. & Shi, P. Y., Dec 1 2020, In: Nature communications. 11, 1, 5214.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
Xia, H., Luo, H., Shan, C., Muruato, A. E., Nunes, B. T. D., Medeiros, D. B. A., Zou, J., Xie, X., Giraldo, M. I., Vasconcelos, P. F. C., Weaver, S. C., Wang, T., Rajsbaum, R. & Shi, P. Y., Dec 1 2018, In: Nature communications. 9, 1, 414.Research output: Contribution to journal › Article › peer-review
95 Scopus citations -
An Infectious cDNA Clone of SARS-CoV-2
Xie, X., Muruato, A., Lokugamage, K. G., Narayanan, K., Zhang, X., Zou, J., Liu, J., Schindewolf, C., Bopp, N. E., Aguilar, P. V., Plante, K. S., Weaver, S. C., Makino, S., LeDuc, J. W., Menachery, V. D. & Shi, P. Y., May 13 2020, In: Cell Host and Microbe. 27, 5, p. 841-848.e3Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
A novel reporter system for neutralizing and enhancing antibody assay against dengue virus
Song, K. Y., Zhao, H., Jiang, Z. Y., Li, X. F., Deng, Y. Q., Jiang, T., Zhu, S. Y., Shi, P. Y., Zhang, B., Zhang, F. C., Qin, E. D. & Qin, C. F., Feb 18 2014, In: BMC Microbiology. 14, 1, 44.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Anti-dengue-virus activity and structure-activity relationship studies of lycorine derivatives
Wang, P., Li, L. F., Wang, Q. Y., Shang, L. Q., Shi, P. Y. & Yin, Z., Jul 2014, In: ChemMedChem. 9, 7, p. 1522-1533 12 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
A positively selected mutation in the WNV 2K peptide confers resistance to superinfection exclusion in vivo
Campbell, C. L., Smith, D. R., Sanchez-Vargas, I., Zhang, B., Shi, P. Y. & Ebel, G. D., Sep 2014, In: Virology. 464-465, 1, p. 228-232 5 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
A Rapid Zika Diagnostic Assay to Measure Neutralizing Antibodies in Patients
Shan, C., Xie, X., Ren, P., Loeffelholz, M. J., Yang, Y., Furuya, A., Dupuis, A. P., Kramer, L. D., Wong, S. J. & Shi, P. Y., Mar 1 2017, In: EBioMedicine. 17, p. 157-162 6 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
A replication-defective Japanese encephalitis virus (JEV) vaccine candidate with NS1 deletion confers dual protection against JEV and West Nile virus in mice
Li, N., Zhang, Z. R., Zhang, Y. N., Liu, J., Deng, C. L., Shi, P. Y., Yuan, Z. M., Ye, H. Q. & Zhang, B., Dec 1 2020, In: npj Vaccines. 5, 1, 73.Research output: Contribution to journal › Article › peer-review
Open Access -
A single amino acid in nonstructural protein NS4B Confers virulence to dengue virus in AG129 mice through enhancement of viral RNA synthesis
Grant, D., Tan, G. K., Qing, M., Ng, J. K. W., Yip, A., Zou, G., Xie, X., Yuan, Z. Y., Schreiber, J., Schul, W., Shi, P. Y. & Alonso, S., Aug 2011, In: Journal of virology. 85, 15, p. 7775-7787 13 p.Research output: Contribution to journal › Article › peer-review
67 Scopus citations -
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
Shan, C., Muruato, A. E., Jagger, B. W., Richner, J., Nunes, B. T. D., Medeiros, D. B. A., Xie, X., Nunes, J. G. C., Morabito, K. M., Kong, W. P., Pierson, T. C., Barrett, A. D., Weaver, S. C., Rossi, S. L., Vasconcelos, P. F. C., Graham, B. S., Diamond, M. S. & Shi, P. Y., Dec 1 2017, In: Nature communications. 8, 1, 676.Research output: Contribution to journal › Article › peer-review
80 Scopus citations -
A Single-Dose Live-Attenuated Zika Virus Vaccine with Controlled Infection Rounds that Protects against Vertical Transmission
Xie, X., Kum, D. B., Xia, H., Luo, H., Shan, C., Zou, J., Muruato, A. E., Medeiros, D. B. A., Nunes, B. T. D., Dallmeier, K., Rossi, S. L., Weaver, S. C., Neyts, J., Wang, T., Vasconcelos, P. F. C. & Shi, P. Y., Oct 10 2018, In: Cell Host and Microbe. 24, 4, p. 487-499.e5Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
A single-dose plasmid-launched live-attenuated Zika vaccine induces protective immunity
Zou, J., Xie, X., Luo, H., Shan, C., Muruato, A. E., Weaver, S. C., Wang, T. & Shi, P. Y., Oct 2018, In: EBioMedicine. 36, p. 92-102 11 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations