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• Conference contribution

  An edge detection approach for mapping of the human cone photoreceptor mosaic using adaptive optics scanning laser ophthalmoscope

  Chitchian, S., Boretsky, A. R., Van Kuijk, F. J. & Motamedi, M., Dec 1 2012, Biomedical Optics, BIOMED 2012. p. BSu3A.17 (Biomedical Optics, BIOMED 2012).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Ophthalmoscopes
  • edge detection
  • Retinal Cone Photoreceptor Cells
  • Ophthalmoscopy
  • photoreceptors
  2 Scopus citations

• Automated retinal layer segmentation and characterization

  Luisi, J., Briley, D., Boretsky, A. & Motamedi, M., Jan 1 2014, Translational Biophotonics. SPIE, 91551N. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9155).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Optical tomography
  • Eye Injuries
  • Choroidal Neovascularization
  • Macular Degeneration
  • Convolution

• Laser injury and in vivo multimodal imaging using a mouse model

  Pocock, G. M., Boretsky, A., Gupta, P., Oliver, J. W. & Motamedi, M., Apr 29 2011, Optical Interactions with Tissue and Cells XXII. 789713. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 7897).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Multimodal Imaging
  • retina
  • mice
  • Optical tomography
  • Retina

• NF-kB activation as a biomarker of light injury using a transgenic mouse model

  Pocock, G. M., Boretsky, A., Wang, H. C., Golden, D., Gupta, P., Vargas, G., Oliver, J. W. & Motamedi, M., Apr 2 2012, Optical Interactions with Tissue and Cells XXIII. 822108. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8221).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • biomarkers
  • Biomarkers
  • enhanced green fluorescent protein
  • NF-kappa B
  • mice

• Retinal OCT image enhancement via wavelet denoising

  Chitchian, S., Mayer, M. A., Boretsky, A. R., Van-Kuijk, F. J. & Motamedi, M., Dec 1 2012, Biomedical Optics, BIOMED 2012. p. BTu3A.73 (Biomedical Optics, BIOMED 2012).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Image Enhancement
  • retinal images
  • image enhancement
  • Wavelet Analysis
  • Retina

• Spatial location tracking using optical coherence tomography-proof of concept for gynecology

  Acharya, M., Vincent, K., Motamedi, M. & Gowda, A., Oct 14 2014, Frontiers in Optics, FiO 2014. Optical Society of America (OSA), (Frontiers in Optics, FiO 2014).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • gynecology
  • Gynecology
  • optical tracking
  • Optical tomography
  • tomography
• Chapter

  Pulsed laser tissue interaction

  Walsh, J. T., Van Leeuwen, T. G., Jansen, E. D., Motamedi, M. & Welch, A. J., Dec 1 2011, Optical-Thermal Response of Laser-Irradiated Tissue. Springer Netherlands, p. 617-649 33 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • pulsed lasers
  • ablation
  • interactions
  • damage
  • lasers
  6 Scopus citations
• Article

  AAV2-mediated GRP78 transfer alleviates retinal neuronal injury by downregulating ER stress and Tau oligomer formation

  Ha, Y., Liu, W., Liu, H., Zhu, S., Xia, F., Gerson, J. E., Azhar, N. A., Tilton, R. G., Motamedi, M., Kayed, R. & Zhang, W., Sep 2018, In: Investigative Ophthalmology and Visual Science. 59, 11, p. 4670-4682 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Nerve Crush
  • Retinal Ganglion Cells
  • Endoplasmic Reticulum Stress
  • Optic Nerve
  • Down-Regulation
  6 Scopus citations

• Automated segmentation algorithm for detection of changes in vaginal epithelial morphology using optical coherence tomography

  Chitchian, S., Vincent, K. L., Vargas, G. & Motamedi, M., Nov 2012, In: Journal of Biomedical Optics. 17, 11, 116004.

  Research output: Contribution to journal › Article › peer-review

  • Optical tomography
  • epithelium
  • tomography
  • Anti-Infective Agents
  • Tissue
  5 Scopus citations

• Critical Role of the CXCL10/C-X-C Chemokine Receptor 3 Axis in Promoting Leukocyte Recruitment and Neuronal Injury during Traumatic Optic Neuropathy Induced by Optic Nerve Crush

  Ha, Y., Liu, H., Zhu, S., Yi, P., Liu, W., Nathanson, J., Kayed, R., Loucas, B., Sun, J., Frishman, L. J., Motamedi, M. & Zhang, W., Feb 1 2017, In: American Journal of Pathology. 187, 2, p. 352-365 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Optic Nerve Injuries
  • Nerve Crush
  • CXC Chemokines
  • Chemokine Receptors
  • Optic Nerve
  17 Scopus citations

• Development of a novel imaging system for cell therapy in the brain

  Micci, M. A., Boone, D. R., Parsley, M. A., Wei, J., Patrikeev, I., Motamedi, M. & Hellmich, H. L., Jul 21 2015, In: Stem Cell Research and Therapy. 6, 1, 131.

  Research output: Contribution to journal › Article › peer-review

  • Stem cells
  • Neural Stem Cells
  • Imaging systems
  • Cell- and Tissue-Based Therapy
  • Brain
  8 Scopus citations

• Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses

  Maroto, R., Zhao, Y., Jamaluddin, M., Popov, V. L., Wang, H., Kalubowilage, M., Zhang, Y., Luisi, J., Sun, H., Culbertson, C. T., Bossmann, S. H., Motamedi, M. & Brasier, A. R., Dec 1 2017, In: Journal of Extracellular Vesicles. 6, 1, 1359478.

  Research output: Contribution to journal › Article › peer-review

  • Exosomes
  • Temperature
  • Bronchoalveolar Lavage Fluid
  • Proteins
  • Dynamic Light Scattering
  54 Scopus citations

• Evaluation of immunological markers of ovine vaginal irritation: Implications for preclinical assessment of non-vaccine HIV preventive agents

  Milligan, G. N., Vargas, G., Vincent, K. L., Zhu, Y., Bourne, N. & Motamedi, M., Nov 2017, In: Journal of Reproductive Immunology. 124, p. 38-43 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Sheep
  • Anti-Infective Agents
  • HIV
  • Therapeutic Irrigation
  • Genitalia

• Imaging of Murine Whole Lung Fibrosis by Large Scale 3D Microscopy aided by Tissue Optical Clearing

  Ochoa, L. F., Kholodnykh, A., Villarreal, P., Tian, B., Pal, R., Freiberg, A. N., Brasier, A. R., Motamedi, M. & Vargas, G., Dec 1 2018, In: Scientific reports. 8, 1, 13348.

  Research output: Contribution to journal › Article › peer-review

  • Microscopy
  • Fibrosis
  • Second Harmonic Generation Microscopy
  • Lung
  • Poly I-C
  11 Scopus citations

• In vivo imaging of photoreceptor disruption associated with age-related macular degeneration: A pilot study

  Boretsky, A., Khan, F., Burnett, G., Hammer, D. X., Daniel Ferguson, R., Van Kuijk, F. & Motamedi, M., Oct 2012, In: Lasers in Surgery and Medicine. 44, 8, p. 603-610 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Macular Degeneration
  • Ophthalmoscopes
  • Photoreceptor Cells
  • Lasers
  • Geographic Atrophy
  37 Scopus citations

• In vivo optoacoustic temperature imaging for image-guided cryotherapy of prostate cancer

  Petrova, E. V., Brecht, H. P., Motamedi, M., Oraevsky, A. A. & Ermilov, S. A., Mar 21 2018, In: Physics in Medicine and Biology. 63, 6, 064002.

  Research output: Contribution to journal › Article › peer-review

  • Cryotherapy
  • Prostatic Neoplasms
  • Temperature
  • Prostate
  • Needles
  12 Scopus citations

• Multispecies Evaluation of a Long-Acting Tenofovir Alafenamide Subdermal Implant for HIV Prophylaxis

  Gunawardana, M., Remedios-Chan, M., Sanchez, D., Webster, S., Galvan, P., Fanter, R., Castonguay, A. E., Webster, P., Moss, J. A., Kuo, J., Gallay, P. A., Vincent, K. L., Motamedi, M., Weinberger, D., Marzinke, M. A., Hendrix, C. W. & Baum, M. M., Nov 25 2020, In: Frontiers in Pharmacology. 11, 569373.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • GS-7340
  • HIV-1
  • Pre-Exposure Prophylaxis
  • HIV
  • HIV Infections

• Neuronal Epac1 mediates retinal neurodegeneration in mouse models of ocular hypertension

  Liu, W., Ha, Y., Xia, F., Zhu, S., Li, Y., Shi, S., Mei, F. C., Merkley, K., Vizzeri, G., Motamedi, M., Cheng, X., Liu, H. & Zhang, W., 2020, In: Journal of Experimental Medicine. 217, 4, e20190930.

  Research output: Contribution to journal › Article › peer-review

  • Ocular Hypertension
  • Retinal Ganglion Cells
  • Glaucoma
  • Retina
  • Calcium-Calmodulin-Dependent Protein Kinase Type 2
  3 Scopus citations

• NF-κB mediates mesenchymal transition, remodeling, and pulmonary fibrosis in response to chronic inflammation by viral RNA patterns

  Tian, B., Patrikeev, I., Ochoa, L., Vargas, G., Belanger, K. A. K., Litvinov, J., Boldogh, I., Ameredes, B. T., Motamedi, M. & Brasier, A. R., Apr 2017, In: American journal of respiratory cell and molecular biology. 56, 4, p. 506-520 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Poly I-C
  • Pulmonary Fibrosis
  • Viral RNA
  • Airway Remodeling
  • 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline
  26 Scopus citations

• Nicotine accelerates diabetes-induced retinal changes

  Boretsky, A., Gupta, P., Tirgan, N., Liu, R., Godley, B. F., Zhang, W., Tilton, R. G. & Motamedi, M., Apr 1 2015, In: Current Eye Research. 40, 4, p. 368-377 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Nicotine
  • Optical Coherence Tomography
  • Ganglia
  • Electronic Nicotine Delivery Systems
  • Tobacco Use Cessation Devices
  11 Scopus citations

• Nicotine exposure exacerbates development of cataracts in a type 1 diabetic rat model

  Tirgan, N., Kulp, G. A., Gupta, P., Boretsky, A., Wiraszka, T. A., Godley, B., Tilton, R. G. & Motamedi, M., 2012, In: Experimental Diabetes Research. 2012, 349320.

  Research output: Contribution to journal › Article › peer-review

  • Cataract
  • Nicotine
  • Diabetes
  • Rat
  • Progression
  9 Scopus citations

• Noninvasive allergic sinus congestion and resolution assessments using microcomputed tomography imaging

  Litvinov, J., Spear, W. C., Patrikeev, I., Motamedi, M. & Ameredes, B. T., Nov 2018, In: Journal of Applied Physiology. 125, 5, p. 1563-1575 13 p.

  Research output: Contribution to journal › Article › peer-review

  • X-Ray Microtomography
  • ragweed pollen
  • Fluticasone
  • Guinea Pigs
  • Air

• Novel effects of simvastatin on uterine fibroid tumors: In vitro and patient-derived xenograft mouse model study

  Borahay, M. A., Vincent, K., Motamedi, M., Sbrana, E., Kilic, G. S., Al-Hendy, A. & Boehning, D., Aug 1 2015, In: American journal of obstetrics and gynecology. 213, 2, p. 196.e1-196.e8

  Research output: Contribution to journal › Article › peer-review

  • Simvastatin
  • Leiomyoma
  • Heterografts
  • In Vitro Techniques
  • thiazolyl blue
  14 Scopus citations

• Optical coherence tomography compared with colposcopy for assessment of vaginal epithelial damage: A randomized controlled trial

  Vincent, K. L., Stanberry, L. R., Moench, T. R., Breitkopf, C. R., Loza, M. L., Wei, J., Grady, J., Paull, J., Motamedi, M. & Rosenthal, S. L., Dec 2011, In: Obstetrics and gynecology. 118, 6, p. 1354-1361 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Colposcopy
  • Nonoxynol
  • Optical Coherence Tomography
  • Randomized Controlled Trials
  • Foams and Jellies Vaginal Creams
  14 Scopus citations

• Pharmacological inhibition and genetic knockdown of exchange protein directly activated by cAMP 1 reduce pancreatic cancer metastasis in vivos

  Almahariq, M., Chao, C., Mei, F. C., Hellmich, M. R., Patrikeev, I., Motamedi, M. & Cheng, X., Feb 1 2015, In: Molecular pharmacology. 87, 2, p. 142-149 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatic Neoplasms
  • Adenocarcinoma
  • Pharmacology
  • Neoplasm Metastasis
  • Proteins
  28 Scopus citations

• Posttranslational modification of Sirt6 activity by peroxynitrite

  Hu, S., Liu, H., Ha, Y., Luo, X., Motamedi, M., Gupta, M. P., Ma, J. X., Tilton, R. G. & Zhang, W., Feb 2015, In: Free Radical Biology and Medicine. 79, p. 176-185 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Sirtuins
  • Peroxynitrous Acid
  • Post Translational Protein Processing
  • Nitration
  • Endothelial cells
  27 Scopus citations

• Quantitative assessment of microbicide-induced injury in the ovine vaginal epithelium using confocal microendoscopy

  Vargas, G., Patrikeev, I., Wei, J., Bell, B., Vincent, K., Bourne, N. & Motamedi, M., Feb 29 2012, In: BMC Infectious Diseases. 12, 48.

  Research output: Contribution to journal › Article › peer-review

  • Benzalkonium Compounds
  • Anti-Infective Agents
  • Sheep
  • Epithelium
  • Wounds and Injuries
  7 Scopus citations

• Quantitative evaluation of retinal response to laser photocoagulation using dual-wavelength fundus autofluorescence imaging in a small animal model

  Boretsky, A., Motamedi, M., Bell, B. & van Kuijk, F., Aug 2011, In: Investigative Ophthalmology and Visual Science. 52, 9, p. 6300-6307 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Light Coagulation
  • Optical Imaging
  • Evaluation Studies
  • Lasers
  • Animal Models
  6 Scopus citations

• Retinal optical coherence tomography image enhancement via shrinkage denoising using double-density dual-tree complex wavelet transform

  Chitchian, S., Mayer, M. A., Boretsky, A. R., Van Kuijk, F. J. & Motamedi, M., Nov 2012, In: Journal of Biomedical Optics. 17, 11, 116009.

  Research output: Contribution to journal › Article › peer-review

  • image enhancement
  • Optical tomography
  • wavelet analysis
  • Image enhancement
  • shrinkage
  21 Scopus citations

• Scattering angle resolved optical coherence tomography detects early changes in 3xTg Alzheimer’s disease mouse model

  Gardner, M. R., Baruah, V., Vargas, G., Motamedi, M., Milner, T. E. & Rylander, H. G., Apr 2020, In: Translational Vision Science and Technology. 9, 5, p. 1-14 14 p., 18.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Optical tomography
  • Optical Coherence Tomography
  • Scattering
  • Alzheimer Disease
  • Imaging techniques

• Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring

  Moss, J. A., Malone, A. M., Smith, T. J., Kennedy, S., Kopin, E., Nguyen, C., Gilman, J., Butkyavichene, I., Vincent, K. L., Motamedi, M., Friend, D. R., Clark, M. R. & Baum, M. M., Feb 2012, In: Antimicrobial agents and chemotherapy. 56, 2, p. 875-882 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Tenofovir
  • Acyclovir
  • Sheep
  • Anti-Infective Agents
  • Rabbits
  69 Scopus citations

• Tenofovir and tenofovir disoproxil fumarate pharmacokinetics from intravaginal rings

  Moss, J. A., Baum, M. M., Malone, A. M., Kennedy, S., Kopin, E., Nguyen, C., Gilman, J., Butkyavichene, I., Willis, R. A., Vincent, K. L., Motamedi, M. & Smith, T. J., Mar 27 2012, In: AIDS. 26, 6, p. 707-710 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Tenofovir
  • Prodrugs
  • Pharmacokinetics
  • Fumarates
  • Sheep
  29 Scopus citations

• TWEAK/Fn14 pathway is a novel mediator of retinal neovascularization

  Ameri, H., Liu, H., Liu, R., Ha, Y., Paulucci-Holthauzen, A. A., Hu, S., Motamedi, M., Godley, B. F., Tilton, R. G. & Zhang, W., Jan 9 2014, In: Investigative Ophthalmology and Visual Science. 55, 2, p. 801-813 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Retinal Neovascularization
  • fibroblast growth factor 14
  • Hypoxia-Inducible Factor 1
  • Hyperoxia
  • Endothelial Cells
  16 Scopus citations