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• Review article

  Surviving Cutaneous Melanoma: A Clinical Review of Follow-up Practices, Surveillance, and Management of Recurrence

  Mrazek, A. A. & Chao, C., Oct 1 2014, In: Surgical Clinics of North America. 94, 5, p. 989-1002 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Practice Management
  • Melanoma
  • Survivorship
  • Recurrence
  • Skin
  19 Scopus citations
• Editorial

  Melanoma

  Brown, K. M. & Chao, C., Oct 1 2014, In: Surgical Clinics of North America. 94, 5, p. xv-xvi

  Research output: Contribution to journal › Editorial › peer-review
• Comment/debate

  Corrigendum to "Role of parathyroid hormone-related protein in the pro-inflammatory and pro-fibrogenic response associated with acute pancreatitis" [Regul Pept 175 (2012) 49-60]

  Bhatia, V., Kim, S. O. K., Aronson, J., Chao, C., Hellmich, M. & Falzon, M., Jun 1 2014, In: Regulatory Peptides. 192, p. 59 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  2 Scopus citations
• Article

  3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics

  Abdollahi Govar, A., Törő, G., Szaniszlo, P., Pavlidou, A., Bibli, S. I., Thanki, K., Resto, V. A., Chao, C., Hellmich, M. R., Szabo, C., Papapetropoulos, A. & Módis, K., Feb 1 2020, In: British Journal of Pharmacology. 177, 4, p. 866-883 18 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-mercaptopyruvic acid
  • Energy Metabolism
  • Endothelial Cells
  • Hydrogen Sulfide
  • Small Interfering RNA
  9 Scopus citations

• Apigenin Decreases Acinar Cell Damage in Pancreatitis

  Mrazek, A. A., Bhatia, V., Falzon, M., Spratt, H., Chao, C. & Hellmich, M. R., May 1 2019, In: Pancreas. 48, 5, p. 711-718 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Apigenin
  • Acinar Cells
  • Pancreatitis
  • Parathyroid Hormone-Related Protein
  • Transforming Growth Factors
  2 Scopus citations

• Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis

  Gao, X., Cao, Y., Staloch, D. A., Gonzales, M. A., Aronson, J. F., Chao, C., Hellmich, M. R. & Ko, T. C., Feb 21 2014, In: PloS one. 9, 2, e89114.

  Research output: Contribution to journal › Article › peer-review

  • bone morphogenetic proteins
  • Ceruletide
  • fibrosis
  • Bone Morphogenetic Proteins
  • Pancreatic Stellate Cells
  17 Scopus citations

• Colorectal cancer-associated fibroblasts are genotypically distinct

  Mrazek, A. A., Carmical, J. R., Wood, T. G., Hellmich, M. R., Eltorky, M. & Chao, C., Jan 1 2014, In: Current Cancer Therapy Reviews. 10, 3, p. 97-218 122 p.

  Research output: Contribution to journal › Article › peer-review

  • Cancer-Associated Fibroblasts
  • Colorectal Neoplasms
  • Fibroblasts
  • Carcinoma
  • Methylation
  12 Scopus citations

• Cystathionine-β-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach

  Chao, C., Zatarain, J. R., Ding, Y., Coletta, C., Mrazek, A. A., Druzhyna, N., Johnson, P., Chen, H., Hellmich, J. L., Asimakopoulou, A., Yanagi, K., Olah, G., Szoleczky, P., Törö, G., Bohanon, F. J., Cheema, M., Lewis, R., Eckelbarger, D., Ahmad, A., Módis, K. & 6 others, Untereiner, A., Szczesny, B., Papapetropoulos, A., Zhou, J., Hellmich, M. R. & Szabo, C., 2016, In: Molecular Medicine. 22, p. 361-379 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Aminooxyacetic Acid
  • Cystathionine
  • Prodrugs
  • Colonic Neoplasms
  • Neoplasms
  26 Scopus citations

• Design, synthesis, and characterization of novel apigenin analogues that suppress pancreatic stellate cell proliferation in vitro and associated pancreatic fibrosis in vivo

  Chen, H., Mrazek, A. A., Wang, X., Ding, C., Ding, Y., Porro, L. J., Liu, H., Chao, C., Hellmich, M. R. & Zhou, J., Jul 1 2014, In: Bioorganic and Medicinal Chemistry. 22, 13, p. 3393-3404 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatic Stellate Cells
  • Cell proliferation
  • Apigenin
  • Chronic Pancreatitis
  • Fibrosis
  25 Scopus citations

• Dual inhibition of PI3K and mTOR signaling pathways decreases human pancreatic neuroendocrine tumor metastatic progression

  Djukom, C., Porro, L. J., Mrazek, A., Townsend, C. M., Hellmich, M. R. & Chao, C., Jan 2014, In: Pancreas. 43, 1, p. 88-92 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Everolimus
  • Neuroendocrine Tumors
  • TOR Serine-Threonine Kinases
  • Phosphatidylinositol 3-Kinase
  • 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
  15 Scopus citations

• Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro

  Módis, K., Coletta, C., Asimakopoulou, A., Szczesny, B., Chao, C., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Sep 15 2014, In: Nitric Oxide - Biology and Chemistry. 41, p. 146-156 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystathionine
  • Cell proliferation
  • S-Adenosylmethionine
  • Energy Metabolism
  • Colorectal Neoplasms
  50 Scopus citations

• Isolation of CD 90+ fibroblast/myofibroblasts from human frozen gastrointestinal specimens

  Johnson, P., Beswick, E. J., Chao, C., Powell, D. W., Hellmich, M. R. & Pinchuk, I. V., Jan 31 2016, In: Journal of Visualized Experiments. 2016, 107, e53691.

  Research output: Contribution to journal › Article › peer-review

  • Fibroblasts
  • Myofibroblasts
  • Tissue
  • Immunohistochemistry
  • Flow cytometry
  9 Scopus citations

• Malignant phyllodes tumor of the breast: A case report

  Al-Zoubaidi, M., Qiu, S., Bonnen, M., Joyner, M., Roehl, K., Silva, C. & Chao, C., 2011, In: Open Breast Cancer Journal. 3, p. 45-48 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Phyllodes Tumor
  • Breast Neoplasms
  • Stromal Cells
  • Breast
  2 Scopus citations

• Medical Students’ Evaluation of Scientific Evidence and Their Justifications for Their Clinical Decisions: a Pilot Study

  Cestone, C., Lewis, R., Aronson, J. F. & Chao, C., Dec 15 2018, In: Medical Science Educator. 28, 4, p. 587-590 4 p.

  Research output: Contribution to journal › Article › peer-review

  • clinical decisions
  • Medical Students
  • medical student
  • Clinical Decision-Making
  • evaluation

• Patient-derived xenografts from colorectal carcinoma: A temporal and hierarchical study of murine stromal cell replacement

  Chao, C., Widen, S. G., Wood, T. G., Zatarain, J. R., Johnson, P., Gajjar, A., Gomez, G., Qiu, S., Thompson, J., Spratt, H. & Hellmich, M. R., Jul 2017, In: Anticancer Research. 37, 7, p. 3405-3412 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Time and Motion Studies
  • Stromal Cells
  • Heterografts
  • Colorectal Neoplasms
  • Nude Mice
  11 Scopus citations

• Regulation of bombesin-stimulated cyclooxygenase-2 expression in prostate cancer cells

  Wen, X., Chao, C., Ives, K. & Hellmich, M. R., Jul 11 2011, In: BMC Molecular Biology. 12, 29.

  Research output: Contribution to journal › Article › peer-review

  • Bombesin
  • Cyclooxygenase 2
  • Prostatic Neoplasms
  • Phosphatidylinositol 3-Kinases
  • NF-kappa B
  8 Scopus citations

• Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer

  Druzhyna, N., Szczesny, B., Olah, G., Módis, K., Asimakopoulou, A., Pavlidou, A., Szoleczky, P., Gerö, D., Yanagi, K., Törö, G., López-García, I., Myrianthopoulos, V., Mikros, E., Zatarain, J. R., Chao, C., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Nov 1 2016, In: Pharmacological Research. 113, p. 18-37 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Benserazide
  • Cystathionine
  • Investigational Therapies
  • Inhibitory Concentration 50
  • Colonic Neoplasms
  30 Scopus citations

• Suspected liposarcoma of the hip by magnetic resonance imaging 3 years after large-volume fat grafting for buttock augmentation

  Bauer, J. D., Riascos, R., Qiu, S. & Chao, C., Sep 1 2014, In: Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery. 34, 7, p. NP66-NP69

  Research output: Contribution to journal › Article › peer-review

• Triple negative breast cancer: A review of clinicopathologic characteristics and treatment options

  Porro, L. J., Mrazek, A. A., Washington, T. M. & Chao, C., May 12 2014, In: Open Breast Cancer Journal. 6, 1, p. 1-8 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Triple Negative Breast Neoplasms
  • Breast Neoplasms
  • estrophilin
  • Hormones
  • Poly(ADP-ribose) Polymerase Inhibitors
  1 Scopus citations

• Upregulation of cystathionine-β-synthase in colonic epithelia reprograms metabolism and promotes carcinogenesis

  Phillips, CN. M., Zatarain, J. R., Nicholls, M. E., Porter, C., Widen, S. G., Thanki, K., Johnson, P., Jawad, M. U., Moyer, M. P., Randall, J. W., Hellmich, J. L., Maskey, M., Qiu, S., Wood, T. G., Druzhyna, N., Szczesny, B., Módis, K., Szabo, C., Chao, C. & Hellmich, M. R., Nov 1 2017, In: Cancer Research. 77, 21, p. 5741-5754 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystathionine
  • Carcinogenesis
  • Epithelium
  • Up-Regulation
  • Genes
  30 Scopus citations