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  • Blake Rasmussen
Article

Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin

Gundermann, D. M., Walker, D. K., Reidy, P. T., Borack, M. S., Dickinson, J. M., Volpi, E. & Rasmussen, B. B., May 15 2014, In : American Journal of Physiology - Endocrinology and Metabolism. 306, 10, p. E1198-E1204

Research output: Contribution to journalArticle

48 Scopus citations

Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism1-3

Glynn, E. L., Fry, C. S., Timmerman, K. L., Drummond, M. J., Volpi, E. & Rasmussen, B. B., Mar 2013, In : Journal of Nutrition. 143, 3, p. 307-314 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Aging and microRNA expression in human skeletal muscle: A microarray and bioinformatics analysis

Drummond, M. J., McCarthy, J. J., Sinha, M., Spratt, H. M., Volpi, E., Esser, K. A. & Rasmussen, B. B., May 2011, In : Physiological Genomics. 43, 10, p. 595-603 9 p.

Research output: Contribution to journalArticle

145 Scopus citations

Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise

Dickinson, J. M., Drummond, M. J., Coben, J. R., Volpi, E. & Rasmussen, B. B., Apr 2013, In : Clinical Nutrition. 32, 2, p. 273-280 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis

Fry, C. S., Drummond, M. J., Glynn, E. L., Dickinson, J. M., Gundermann, D. M., Timmerman, K. L., Walker, D. K., Dhanani, S., Volpi, E. & Rasmussen, B. B., Mar 2 2011, In : Skeletal Muscle. 1, 1, 11.

Research output: Contribution to journalArticle

197 Scopus citations

A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults

Timmerman, K. L., Dhanani, S., Glynn, E. L., Fry, C. S., Drummond, M. J., Jennings, K., Rasmussen, B. B. & Volpi, E., Jun 1 2012, In : American Journal of Clinical Nutrition. 95, 6, p. 1403-1412 10 p.

Research output: Contribution to journalArticle

82 Scopus citations

A soy, whey and caseinate blend extends postprandial skeletal muscle protein synthesis in rats

Butteiger, D. N., Cope, M., Liu, P., Mukherjea, R., Volpi, E., Rasmussen, B. B. & Krul, E. S., Aug 2013, In : Clinical Nutrition. 32, 4, p. 585-591 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

ATF4 Is a Fundamental Regulator of Nutrient Sensing and Protein Turnover

Rasmussen, B. B. & Adams, C. M., May 1 2020, In : The Journal of nutrition. 150, 5, p. 979-980 2 p.

Research output: Contribution to journalArticle

Open Access

Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults

Drummond, M. J., Dickinson, J. M., Fry, C. S., Walker, D. K., Gundermann, D. M., Reidy, P. T., Timmerman, K. L., Markofski, M. M., Paddon-Jones, D., Rasmussen, B. B. & Volpi, E., May 1 2012, In : American Journal of Physiology - Endocrinology and Metabolism. 302, 9, p. E1113-E1122

Research output: Contribution to journalArticle

115 Scopus citations

Blunted IL-6 and IL-10 response to maximal aerobic exercise in patients with traumatic brain injury

Timmerman, K. L., Amonette, W. E., Markofski, M. M., Ansinelli, H. A., Gleason, E. A., Rasmussen, B. & Mossberg, K. A., Jan 17 2015, In : European Journal of Applied Physiology. 115, 1, p. 111-118 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Deficiency in Repair of the Mitochondrial Genome Sensitizes Proliferating Myoblasts to Oxidative Damage

Szczesny, B., Olah, G., Walker, D. K., Volpi, E., Rasmussen, B. B., Szabo, C. & Mitra, S., Sep 16 2013, In : PloS one. 8, 9, e75201.

Research output: Contribution to journalArticle

27 Scopus citations

Defining meal requirements for protein to optimize metabolic roles of amino acids

Layman, D. K., Anthony, T. G., Rasmussen, B. B., Adams, S. H., Lynch, C. J., Brinkworth, G. D. & Davis, T. A., Jun 1 2015, In : American Journal of Clinical Nutrition. 101, 6, p. 1330S-1338S

Research output: Contribution to journalArticle

55 Scopus citations

Effect of aerobic exercise training and essential amino acid supplementation for 24 weeks on physical function, body composition, and muscle metabolism in healthy, independent older adults: A randomized clinical trial

Markofski, M. M., Jennings, K., Timmerman, K. L., Dickinson, J. M., Fry, C. S., Borack, M. S., Reidy, P. T., Deer, R. R., Randolph, A., Rasmussen, B. B. & Volpi, E., Oct 1 2019, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 10, p. 1598-1604 7 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

Markofski, M. M., Dickinson, J. M., Drummond, M. J., Fry, C. S., Fujita, S., Gundermann, D. M., Glynn, E. L., Jennings, K., Paddon-Jones, D., Reidy, P. T., Sheffield-Moore, M., Timmerman, K. L., Rasmussen, B. B. & Volpi, E., May 1 2015, In : Experimental Gerontology. 65, p. 1-7 7 p.

Research output: Contribution to journalArticle

63 Scopus citations

Effect of essential amino acid supplementation and aerobic exercise on insulin sensitivity in healthy older adults: A randomized clinical trial

Randolph, A. C., Markofski, M. M., Rasmussen, B. B. & Volpi, E., May 2020, In : Clinical Nutrition. 39, 5, p. 1371-1378 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
29 Scopus citations

Exercise, amino acids, and aging in the control of human muscle protein synthesis

Walker, D. K., Dickinson, J. M., Timmerman, K. L., Drummond, M. J., Reidy, P. T., Fry, C. S., Gundermann, D. M. & Rasmussen, B. B., Dec 2011, In : Medicine and Science in Sports and Exercise. 43, 12, p. 2249-2258 10 p.

Research output: Contribution to journalArticle

75 Scopus citations

Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle

Dickinson, J. M., Volpi, E. & Rasmussen, B. B., Oct 1 2013, In : Exercise and Sport Sciences Reviews. 41, 4, p. 216-223 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Human and Mouse Brown Adipose Tissue Mitochondria Have Comparable UCP1 Function

Porter, C., Herndon, D. N., Chondronikola, M., Chao, T., Annamalai, P., Bhattarai, N., Saraf, M. K., Capek, K. D., Reidy, P. T., Daquinag, A. C., Kolonin, M. G., Rasmussen, B. B., Borsheim, E., Toliver-Kinsky, T. & Sidossis, L., Aug 9 2016, In : Cell Metabolism. 24, 2, p. 246-255 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

Hypermetabolism and hypercatabolism of skeletal muscle accompany mitochondrial stress following severe burn trauma

Ogunbileje, J. O., Porter, C., Herndon, D. N., Chao, T., Abdelrahman, D. R., Papadimitriou, A., Chondronikola, M., Zimmers, T. A., Reidy, P. T., Rasmussen, B. B. & Sidossis, L., Aug 1 2016, In : American Journal of Physiology - Endocrinology and Metabolism. 311, 2, p. E436-E448

Research output: Contribution to journalArticle

15 Scopus citations

Increasing insulin availability does not augment postprandial muscle protein synthesis rates in healthy young and older men

Groen, B. B. L., Horstman, A. M. H., Hamer, H. M., De Haan, M., Van Kranenburg, J., Bierau, J., Poeze, M., Wodzig, W. K. W. H., Rasmussen, B. B. & Van Loon, L. J. C., Nov 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 11, p. 3978-3988 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Influence of ageing and essential amino acids on quantitative patterns of troponin T alternative splicing in human skeletal muscle

Coble, J., Schilder, R. J., Berg, A., Drummond, M. J., Rasmussen, B. & Kimball, S. R., Mar 30 2015, In : Applied Physiology, Nutrition and Metabolism. 40, 8, p. 788-796 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells

Walker, D. K., Drummond, M. J., Dickinson, J. M., Borack, M. S., Jennings, K., Volpi, E. & Rasmussen, B. B., 2014, In : Physiological reports. 2, 3, e00238.

Research output: Contribution to journalArticle

20 Scopus citations

Leucine-enriched Amino acid ingestion after resistance exercise prolongs myofibrillar protein synthesis and amino acid transporter expression in older men

Dickinson, J. M., Gundermann, D. M., Walker, D. K., Reidy, P. T., Borack, M. S., Drummond, M. J., Arora, M., Volpi, E. & Rasmussen, B. B., 2014, In : Journal of Nutrition. 144, 11, p. 1694-1702 9 p.

Research output: Contribution to journalArticle

56 Scopus citations

Long-term skeletal muscle mitochondrial dysfunction is associated with hypermetabolism in severely burned children

Porter, C., Herndon, D. N., Børsheim, E., Bhattarai, N., Chao, T., Reidy, P. T., Rasmussen, B. B., Andersen, C. R., Suman, O. E. & Sidossis, L. S., 2016, In : Journal of Burn Care and Research. 37, 1, p. 53-63 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults

Moro, T., Brightwell, C. R., Phalen, D. E., McKenna, C. F., Lane, S. J., Porter, C., Volpi, E., Rasmussen, B. B. & Fry, C., Nov 2019, In : Experimental Gerontology. 127, 110723.

Research output: Contribution to journalArticle

7 Scopus citations

Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids

Dickinson, J. M., Fry, C. S., Drummond, M. J., Gundermann, D. M., Walker, D. K., Glynn, E. L., Timmerman, K. L., Dhanani, S., Volpi, E. & Rasmussen, B. B., May 1 2011, In : Journal of Nutrition. 141, 5, p. 856-862 7 p.

Research output: Contribution to journalArticle

151 Scopus citations

Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle

Porter, C., Hurren, N. M., Cotter, M. V., Bhattarai, N., Reidy, P. T., Dillon, E., Durham, W. J., Tuvdendorj, D., Sheffield-Moore, M., Volpi, E., Sidossis, L. S., Rasmussen, B. & Børsheim, E., Aug 5 2015, In : American Journal of Physiology - Endocrinology and Metabolism. 309, 3, p. E224-E232

Research output: Contribution to journalArticle

53 Scopus citations

Muscle protein anabolic resistance to essential amino acids does not occur in healthy older adults before or after resistance exercise training

Moro, T., Brightwell, C. R., Deer, R. R., Graber, T. G., Galvan, E., Fry, C. S., Volpi, E. & Rasmussen, B. B., Jun 1 2018, In : Journal of Nutrition. 148, 6, p. 900-909 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Paraplegia increases skeletal muscle autophagy

Fry, C. S., Drummond, M. J., Lujan, H. L., Dicarlo, S. E. & Rasmussen, B. B., Nov 2012, In : Muscle and Nerve. 46, 5, p. 793-798 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

PAX7+ satellite cells in young and older adults following resistance exercise

Walker, D. K., Fry, C. S., Drummond, M. J., Dickinson, J. M., Timmerman, K. L., Gundermann, D. M., Jennings, K., Volpi, E. & Rasmussen, B. B., Jul 2012, In : Muscle and Nerve. 46, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Post-absorptive muscle protein turnover affects resistance training hypertrophy

Reidy, P. T., Borack, M. S., Markofski, M. M., Dickinson, J. M., Fry, C. S., Deer, R. R., Volpi, E. & Rasmussen, B. B., May 1 2017, In : European Journal of Applied Physiology. 117, 5, p. 853-866 14 p.

Research output: Contribution to journalArticle

15 Scopus citations

Postexercise essential amino acid supplementation amplifies skeletal muscle satellite cell proliferation in older men 24 hours postexercise

Reidy, P. T., Fry, C. S., Dickinson, J. M., Drummond, M. J. & Rasmussen, B. B., Jun 2017, In : Physiological reports. 5, 11, e13269.

Research output: Contribution to journalArticle

5 Scopus citations

Post-prandial protein handling: You are what you just ate

Groen, B. B. L., Horstman, A. M., Hamer, H. M., De Haan, M., Van Kranenburg, J., Bierau, J., Poeze, M., Wodzig, W. K. W. H., Rasmussen, B. B. & Van Loon, L. J. C., Nov 10 2015, In : PloS one. 10, 11, e0141582.

Research output: Contribution to journalArticle

38 Scopus citations

Protein blend ingestion following resistance exercise promotes human muscle protein synthesis

Reidy, P. T., Walker, D. K., Dickinson, J. M., Gundermann, D. M., Drummond, M. J., Timmerman, K. L., Fry, C. S., Borack, M. S., Cope, M. B., Mukherjea, R., Jennings, K., Volpi, E. & Rasmussen, B. B., Apr 1 2013, In : Journal of Nutrition. 143, 4, p. 410-416 7 p.

Research output: Contribution to journalArticle

81 Scopus citations

Protein supplementation does not affect myogenic adaptations to resistance training

Reidy, P. T., Fry, C. S., Igbinigie, S., Deer, R. R., Jennings, K., Cope, M. B., Mukherjea, R., Volpi, E. & Rasmussen, B. B., 2017, In : Medicine and Science in Sports and Exercise. 49, 6, p. 1197-1208 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Protein supplementation has minimal effects on muscle adaptations during resistance exercise training in young men: A double-blind randomized clinical trial

Reidy, P. T., Borack, M. S., Markofski, M. M., Dickinson, J. M., Deer, R. R., Husaini, S. H., Walker, D. K., Igbinigie, S., Robertson, S. M., Cope, M. B., Mukherjea, R., Hall-Porter, J. M., Jennings, K., Volpi, E. & Rasmussen, B. B., 2016, In : Journal of Nutrition. 146, 9, p. 1660-1669 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle

Dickinson, J. M., Drummond, M. J., Fry, C. S., Gundermann, D. M., Walker, D. K., Timmerman, K. L., Volpi, E. & Rasmussen, B. B., Jan 2013, In : Metabolism: Clinical and Experimental. 62, 1, p. 144-151 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Reactive hyperemia is not responsible for stimulating muscle protein synthesis following blood flow restriction exercise

Gundermann, D. M., Fry, C. S., Dickinson, J. M., Walker, D. K., Timmerman, K. L., Drummond, M. J., Volpi, E. & Rasmussen, B. B., May 1 2012, In : Journal of Applied Physiology. 112, 9, p. 1520-1528 9 p.

Research output: Contribution to journalArticle

55 Scopus citations

Repetitive TLR3 activation in the lung induces skeletal muscle adaptations and cachexia

Graber, T. G., Rawls, B. L., Tian, B., Durham, W. J., Brightwell, C. R., Brasier, A. R., Rasmussen, B. B. & Fry, C. S., Jun 2018, In : Experimental Gerontology. 106, p. 88-100 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Resistance Exercise Training Alters Mitochondrial Function in Human Skeletal Muscle

Porter, C., Reidy, P. T., Bhattarai, N., Sidossis, L. S. & Rasmussen, B. B., Sep 18 2015, In : Medicine and Science in Sports and Exercise. 47, 9, p. 1922-1931 10 p.

Research output: Contribution to journalArticle

64 Scopus citations

Resistance exercise training promotes fiber type-specific myonuclear adaptations in older adults

Moro, T., Brightwell, C. R., Volpi, E., Rasmussen, B. B. & Fry, C., Jan 1 2020, In : Journal of Applied Physiology. 128, 4, p. 795-804 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Role of ingested amino acids and protein in the promotion of resistance exercise-induced muscle protein anabolism

Reidy, P. T. & Rasmussen, B. B., 2016, In : Journal of Nutrition. 146, 2, p. 155-183 29 p.

Research output: Contribution to journalArticle

56 Scopus citations

Satellite cell activation and apoptosis in skeletal muscle from severely burned children

Fry, C. S., Porter, C., Sidossis, L. S., Nieten, C., Reidy, P. T., Hundeshagen, G., Mlcak, R., Rasmussen, B. B., Lee, J. O., Suman, O. E., Herndon, D. N. & Finnerty, C. C., Sep 15 2016, In : Journal of Physiology. 594, 18, p. 5223-5236 14 p.

Research output: Contribution to journalArticle

27 Scopus citations

Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults

Drummond, M. J., Timmerman, K. L., Markofski, M. M., Walker, D. K., Dickinson, J. M., Jamaluddin, M., Brasier, A. R., Rasmussen, B. B. & Volpi, E., Aug 1 2013, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 305, 3, p. R216-R223

Research output: Contribution to journalArticle

55 Scopus citations

Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise

Drummond, M. J., Fry, C. S., Glynn, E. L., Timmerman, K. L., Dickinson, J. M., Walker, D. K., Gundermann, D. M., Volpi, E. & Rasmussen, B. B., Jul 2011, In : Journal of Applied Physiology. 111, 1, p. 135-142 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults

Fry, C. S., Drummond, M. J., Glynn, E. L., Dickinson, J. M., Gundermann, D. M., Timmerman, K. L., Walker, D. K., Volpi, E. & Rasmussen, B. B., May 2013, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 68, 5, p. 599-607 9 p.

Research output: Contribution to journalArticle

88 Scopus citations

Skeletal muscle protein balance and metabolism in the elderly

Fry, C. S. & Rasmussen, B. B., Dec 2011, In : Current Aging Science. 4, 3, p. 260-268 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Skeletal muscle–specific knockout of DEP domain containing 5 protein increases mTORC1 signaling, muscle cell hypertrophy, and mitochondrial respiration

Graber, T. G., Fry, C. S., Brightwell, C. R., Moro, T., Maroto, R., Bhattarai, N., Porter, C., Wakamiya, M. & Rasmussen, B. B., Mar 15 2019, In : Journal of Biological Chemistry. 294, 11, p. 4091-4102 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations