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A Hematogenously Disseminated Orientia tsutsugamsushi-Infected Murine Model of Scrub Typhus
Shelite, T. R., Saito, T. B., Mendell, N. L., Gong, B., Xu, G., Soong, L., Valbuena, G., Bouyer, D. H. & Walker, D. H., Jul 2014, In: PLoS neglected tropical diseases. 8, 7, e2966.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Annexin a2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and ebola virus infections
Su, Z., Chang, Q., Drelich, A., Shelite, T., Judy, B., Liu, Y., Xiao, J., Zhou, C., He, X., Jin, Y., Saito, T., Tang, S., Soong, L., Wakamiya, M., Fang, X., Bukreyev, A., Ksiazek, T., Russell, W. K. & Gong, B., Jul 2020, In: PLoS neglected tropical diseases. 14, 7, p. 1-30 30 p., e0007960.Research output: Contribution to journal › Article › peer-review
Open Access -
A variant in the promoter of MBL2 is associated with protection against visceral leishmaniasis in Morocco
Hamdi, S., Ejghal, R., Idrissi, M., Ezzikouri, S., Hida, M., Soong, L., Amarouch, H. & Lemrani, M., Jan 1 2013, In: Infection, Genetics and Evolution. 13, 1, p. 162-167 6 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
CD4+ T cell-dependent macrophage activation modulates sustained ps exposure on intracellular amastigotes of leishmania amazonensis
Wanderley, J. L. M., Deolindo, P., Carlsen, E., Portugal, A. B., DaMatta, R. A., Barcinski, M. A. & Soong, L., 2019, In: Frontiers in Cellular and Infection Microbiology. 9, APR, 105.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
CD8+T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection
Xu, G., Mendell, N. L., Liang, Y., Shelite, T. R., Goez-Rivillas, Y., Soong, L., Bouyer, D. H. & Walker, D. H., Jul 19 2017, In: PLoS neglected tropical diseases. 11, 7, e0005763.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Differential, type i interferon-mediated autophagic trafficking of hepatitis C virus proteins in mouse liver
Desai, M. M., Gong, B., Chan, T., Davey, R. A., Soong, L., Kolokoltsov, A. A. & Sun, J., Aug 2011, In: Gastroenterology. 141, 2, p. 674-685.e6Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Differential microbicidal effects of human histone proteins H2A and H2B on Leishmania promastigotes and amastigotes
Wang, Y., Chen, Y., Xin, L., Beverley, S. M., Carlsen, E. D., Popov, V., Chang, K. P., Wang, M. & Soong, L., Mar 2011, In: Infection and immunity. 79, 3, p. 1124-1133 10 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
Downregulation of microRNA-107 in intestinal CD11c+ myeloid cells in response to microbiota and proinflammatory cytokines increases IL-23p19 expression
Xue, X., Cao, A. T., Cao, X., Yao, S., Carlsen, E. D., Soong, L., Liu, C. G., Liu, X., Liu, Z., Duck, L. W., Elson, C. O. & Cong, Y., Mar 2014, In: European Journal of Immunology. 44, 3, p. 673-682 10 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
Early IL-17 production by intrahepatic T cells is important for adaptive immune responses in viral hepatitis
Hou, L., Jie, Z., Desai, M., Liang, Y., Soong, L., Wang, T. & Sun, J., Jan 15 2013, In: Journal of Immunology. 190, 2, p. 621-629 9 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
Epigenetic suppression of HIV in myeloid cells by the BRD4-selective small molecule modulator ZL0580
Alamer, E., Zhong, C., Liu, Z., Niu, Q., Long, F., Guo, L., Gelman, B. B., Soong, L., Zhou, J. & Hu, H., Jun 1 2020, In: Journal of virology. 94, 11, e01880-19.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Exposure of phosphatidylserine on leishmania amazonensis isolates is associated with diffuse cutaneous leishmaniasis and parasite infectivity
França-Costa, J., Wanderley, J. L. M., Deolindo, P., Zarattini, J. B., Costa, J., Soong, L., Barcinski, M. A., Barral, A. & Borges, V. M., May 4 2012, In: PloS one. 7, 5, e36595.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
Functional interferon system is required for clearance of Lassa virus
Yun, N. E., Poussard, A. L., Seregin, A. V., Walker, A. G., Smith, J. K., Aronson, J. F., Smith, J. N., Soong, L. & Paessler, S., Mar 2012, In: Journal of virology. 86, 6, p. 3389-3392 4 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
Hepatocyte growth factor in dampening liver immune-mediated pathology in acute viral hepatitis without compromising antiviral activity
Aguilar-Valenzuela, R., Carlsen, E. D., Liang, Y., Soong, L. & Sun, J., Apr 2014, In: Journal of Gastroenterology and Hepatology (Australia). 29, 4, p. 878-886 9 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway
Lu, Y., Li, C. F., Ping, N. N., Sun, Y. Y., Wang, Z., Zhao, G. X., Yuan, S. H., Zibrila, A. I., Soong, L. & Liu, J. J., May 1 2020, In: Journal of Biochemical and Molecular Toxicology. 34, 5, e22467.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
IL-22 hinders antiviral T cell responses and exacerbates ZIKV encephalitis in immunocompetent neonatal mice
Liang, Y., Yi, P., Ru, W., Jie, Z., Wang, H., Ghanayem, T., Wang, X., Alamer, E., Liu, J., Hu, H., Soong, L., Cai, J. & Sun, J., Aug 25 2020, In: Journal of neuroinflammation. 17, 1, 249.Research output: Contribution to journal › Article › peer-review
Open Access -
IL-33 induces immunosuppressive neutrophils via a type 2 innate lymphoid cell/IL-13/STAT6 axis and protects the liver against injury in LCMV infection-induced viral hepatitis
Liang, Y., Yi, P., Yuan, D. M. K., Jie, Z., Kwota, Z., Soong, L., Cong, Y. & Sun, J., Feb 1 2019, In: Cellular and Molecular Immunology. 16, 2, p. 126-137 12 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
IL-33 induces nuocytes and modulates liver injury in viral hepatitis
Liang, Y., Jie, Z., Hou, L., Aguilar-Valenzuela, R., Vu, D., Soong, L. & Sun, J., Jun 1 2013, In: Journal of Immunology. 190, 11, p. 5666-5675 10 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
Immunomodulatory and antibacterial effects of cystatin 9 against Francisella tularensis
Eaves-Pyles, T., Patel, J., Arigi, E., Cong, Y., Cao, A., Garg, N., Dhiman, M., Pyles, R. B., Arulanandam, B., Miller, A. L., Popov, V. L., Soong, L., Carlsen, E. D., Coletta, C., Szabo, C. & Almeida, I. C., 2013, In: Molecular Medicine. 19, 1, p. 263-275 13 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Immunotherapy using anti-PD-1 and anti-PD-L1 in Leishmania amazonensis-infected BALB/c mice reduce parasite load
da Fonseca-Martins, A. M., Ramos, T. D., Pratti, J. E. S., Firmino-Cruz, L., Gomes, D. C. O., Soong, L., Saraiva, E. M. & de Matos Guedes, H. L., Dec 1 2019, In: Scientific reports. 9, 1, 20275.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection
Jie, Z., Liang, Y., Hou, L., Dong, C., Iwakura, Y., Soong, L., Cong, Y. & Sun, J., Apr 1 2014, In: Journal of Immunology. 192, 7, p. 3289-3300 12 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
Leishmania amazonensis Amastigotes Highly Express a Tryparedoxin Peroxidase Isoform That Increases Parasite Resistance to Macrophage Antimicrobial Defenses and Fosters Parasite Virulence
Henard, C. A., Carlsen, E. D., Hay, C., Kima, P. E. & Soong, L., Jul 2014, In: PLoS neglected tropical diseases. 8, 7, e3000.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms
Carlsen, E. D., Hay, C., Henard, C. A., Popov, V., Garg, N. J. & Soong, L., Nov 2013, In: Infection and immunity. 81, 11, p. 3966-3974 9 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Multistrain influenza protection induced by a nanoparticulate mucosal immunotherapeutic
Tai, W., Roberts, L., Seryshev, A., Gubatan, J. M., Bland, C. S., Zabriskie, R., Kulkarni, S., Soong, L., Mbawuike, I., Gilbert, B., Kheradmand, F. & Corry, D. B., Mar 2011, In: Mucosal Immunology. 4, 2, p. 197-207 11 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Outcomes of Congenital Zika Disease Depend on Timing of Infection and Maternal-Fetal Interferon Action
Chen, J., Liang, Y., Yi, P., Xu, L., Hawkins, H. K., Rossi, S. L., Soong, L., Cai, J., Menon, R. & Sun, J., Nov 7 2017, In: Cell Reports. 21, 6, p. 1588-1599 12 p.Research output: Contribution to journal › Article › peer-review
46 Scopus citations -
Parenchymal expression of CD40 exacerbates adenovirus-induced hepatitis in mice
Yan, J., Jie, Z., Hou, L., Wanderley, J. L., Soong, L., Gupta, S., Qiu, S., Chan, T. & Sun, J., May 2011, In: Hepatology. 53, 5, p. 1455-1467 13 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Phosphatidylserine exposure on the surface of Leishmania amazonensis amastigotes modulates in vivo infection and dendritic cell function
Wanderley, J. L. M., Thorpe, P. E., Barcinski, M. A. & Soong, L., Mar 2013, In: Parasite Immunology. 35, 3-4, p. 109-119 11 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Polarized lung inflammation and Tie2/angiopoietin-mediated endothelial dysfunction during severe Orientia tsutsugamushi infection
Trent, B., Liang, Y., Xing, Y., Esqueda, M., Wei, Y., Cho, N. H., Kim, H. I., Kim, Y. S., Shelite, T. R., Cai, J., Sun, J., Bouyer, D. H., Liu, J. & Soong, L., Mar 1 2020, In: PLoS neglected tropical diseases. 14, 3, p. e0007675Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Priming and activation of inflammasome by canarypox virus vector alvac via the CGAS/IFI16-sting-type I IFN pathway and AIM2 sensor
Liu, F., Niu, Q., Fan, X., Liu, C., Zhang, J., Wei, Z., Hou, W., Kanneganti, T. D., Robb, M. L., Kim, J. H., Michael, N. L., Sun, J., Soong, L. & Hu, H., Nov 1 2017, In: Journal of Immunology. 199, 9, p. 3293-3305 13 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Retinoic acid modulates hyperactive T cell responses and protects Vitamin A deficient mice against persistent lymphocytic choriomeningitis virus infection
Liang, Y., Yi, P., Wang, X., Zhang, B., Jie, Z., Soong, L. & Sun, J., Jun 1 2020, In: Journal of Immunology. 204, 11, p. 2984-2994 11 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Retinoic acid regulates immune responses by promoting IL-22 and modulating S100 proteins in viral hepatitis
Jie, Z., Liang, Y., Yi, P., Tang, H., Soong, L., Cong, Y., Zhang, K. & Sun, J., May 1 2017, In: Journal of Immunology. 198, 9, p. 3448-3460 13 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Sphingolipid degradation by Leishmania major is required for its resistance to acidic pH in the mammalian host
Xu, W., Xin, L., Soong, L. & Zhang, K., Aug 2011, In: Infection and immunity. 79, 8, p. 3377-3387 11 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
Splenic CD4+ T cells in progressive visceral leishmaniasis show a mixed effector-regulatory phenotype and impair macrophage effector function through inhibitory receptor expression
Medina-Colorado, A. A., Osorio, E. Y., Saldarriaga, O. A., Travi, B. L., Kong, F., Spratt, H., Soong, L. & Melby, P. C., Jan 2017, In: PloS one. 12, 1, e0169496.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice
Soong, L., Wang, H., Shelite, T. R., Liang, Y., Mendell, N. L., Sun, J., Gong, B., Valbuena, G. A., Bouyer, D. H. & Walker, D. H., Sep 1 2014, In: PLoS neglected tropical diseases. 8, 9Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Systemic treatment with cpg-b after sublethal rickettsial infection induces mouse death through indoleamine 2,3-dioxygenase (ido)
Xin, L., Shelite, T. R., Gong, B., Mendell, N. L., Soong, L., Fang, R. & Walker, D. H., Mar 28 2012, In: PloS one. 7, 3, e34062.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
The burden of leishmaniasis in Iran, acquired from the global burden of disease during 1990-2010
Badirzadeh, A., Mohebali, M., Asadgol, Z., Soong, L., Zeinali, M., Mokhayeri, Y., Shirzadi, M. R. & Spotin, A., Sep 1 2017, In: Asian Pacific Journal of Tropical Disease. 7, 9, p. 513-518 6 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
The co-stimulatory effects of MyD88-dependent toll-like receptor signaling on activation of murine γδ T Cells
Zhang, J., Wang, J., Pang, L., Xie, G., Welte, T., Saxena, V., Wicker, J., Mann, B., Soong, L., Barrett, A., Born, W., O'Brien, R. & Wang, T., Sep 18 2014, In: PloS one. 9, 9, A1350.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
The magnitude of CD4+ T-cell activation rather than TCR diversity determines the outcome of Leishmania infection in mice
Xin, L., Wanderley, J. L., Wang, Y., Vargas-Inchaustegui, D. A. & Soong, L., Mar 2011, In: Parasite Immunology. 33, 3, p. 170-180 11 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Type 1-skewed neuroinflammation and vascular damage associated with Orientia tsutsugamushi infection in mice
Soong, L., Shelite, H. T. R., Xing, Y., Kodakandla, H., Liang, Y., Trent, B. J., Horton, P., Smith, K. C., Zhao, Z., Sun, J., Bouyer, D. H. & Cai, J., Jul 24 2017, In: PLoS neglected tropical diseases. 11, 7, e0005765.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Viral retinopathy in experimental models of zika infection
Zhao, Z., Yang, M., Azar, S. R., Soong, L., Weaver, S. C., Sun, J., Chen, Y., Rossi, S. L. & Cai, J., Aug 2017, In: Investigative Ophthalmology and Visual Science. 58, 10, p. 4075-4085 11 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
γδ T cells as a major source of IL-17 production during age-dependent RPE degeneration
Zhao, Z., Xu, P., Jie, Z., Zuo, Y., Yu, B., Soong, L., Sun, J., Chen, Y. & Cai, J., 2014, In: Investigative ophthalmology & visual science. 55, 10, p. 6580-6589 10 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Review article
Immunopathogenesis of non-healing American cutaneous leishmaniasis and progressive visceral leishmaniasis
Soong, L., Henard, C. A. & Melby, P. C., Nov 2012, In: Seminars in Immunopathology. 34, 6, p. 735-751 17 p.Research output: Contribution to journal › Review article › peer-review
67 Scopus citations -
Neuroinflammation associated with scrub typhus and spotted fever group rickettsioses
Fisher, J., Card, G. & Soong, L., Oct 2020, In: PLoS neglected tropical diseases. 14, 10, p. 1-15 15 p., e0008675.Research output: Contribution to journal › Review article › peer-review
Open Access -
Scrub Typhus Pathogenesis: Innate Immune Response and Lung Injury During Orientia tsutsugamushi Infection
Trent, B., Fisher, J. & Soong, L., Sep 6 2019, In: Frontiers in Microbiology. 10, 2065.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
Subversion and utilization of host innate defense by Leishmania amazonensis
Soong, L., 2012, In: Frontiers in immunology. 3, MAR, Article 58.Research output: Contribution to journal › Review article › peer-review
36 Scopus citations -
Short survey
IFNα/β and autophagy: Tug-of-war between HCV and the host
Sun, J., Desai, M. M., Soong, L. & Ou, J. H. J., Nov 2011, In: Autophagy. 7, 11, p. 1394-1396 3 p.Research output: Contribution to journal › Short survey › peer-review
14 Scopus citations -
Interferon gamma in leishmaniasis
Kima, P. E. & Soong, L., 2013, In: Frontiers in immunology. 4, JUN, Article 156.Research output: Contribution to journal › Short survey › peer-review
50 Scopus citations