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• Article

  Alveolar macrophages contribute to the pathogenesis of human metapneumovirus infection while protecting against respiratory syncytial virus infection

  Kolli, D., Gupta, M. R., Sbrana, E., Velayutham, T. S., Chao, H., Casola, A. & Garofalo, R. P., Oct 1 2014, In: American journal of respiratory cell and molecular biology. 51, 4, p. 502-515 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Alveolar Macrophages
  • Metapneumovirus
  • Respiratory Syncytial Virus Infections
  • Viruses
  • Infection
  51 Scopus citations

• Antioxidant mimetics modulate oxidative stress and cellular signaling in airway epithelial cells infected with respiratory syncytial virus

  Hosakote, Y. M., Komaravelli, N., Mautemps, N., Liu, T., Garofalo, R. P. & Casola, A., 2012, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 303, 11, p. L991-L1000

  Research output: Contribution to journal › Article › peer-review

  • Respiratory Syncytial Viruses
  • N,N'-bis(salicylideneamino)ethane-manganese(II)
  • Antioxidants
  • Oxidative Stress
  • Epithelial Cells
  35 Scopus citations

• Antiviral and immunomodulatory activity of silver nanoparticles in experimental rsv infection

  Morris, D., Ansar, M., Speshock, J., Ivanciuc, T., Qu, Y., Casola, A. & Garofalo, R., Aug 2019, In: Viruses. 11, 8, 732.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Respiratory Syncytial Viruses
  • Silver
  • Nanoparticles
  • Antiviral Agents
  • Respiratory Syncytial Virus Infections
  18 Scopus citations

• A polymorphism in the catalase gene promoter confers protection against severe RSV bronchiolitis

  Chambliss, J. M., Ansar, M., Kelley, J. P., Spratt, H., Garofalo, R. P. & Casola, A., Jan 3 2020, In: Viruses. 12, 1, , 57.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bronchiolitis
  • Respiratory Syncytial Viruses
  • Catalase
  • NF-E2-Related Factor 2
  • Antioxidants
  3 Scopus citations

• CDK9-dependent transcriptional elongation in the innate interferon-stimulated gene response to respiratory syncytial virus infection in airway epithelial cells

  Tian, B., Zhao, Y., Kalita, M., Edeh, C. B., Paessler, S., Casola, A., Teng, M. N., Garofalo, R. P. & Brasier, A. R., Jun 2013, In: Journal of virology. 87, 12, p. 7075-7092 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclin-Dependent Kinase 9
  • Respiratory syncytial virus
  • Interferon Regulatory Factor-3
  • Respiratory Syncytial Virus Infections
  • cyclin-dependent kinase
  41 Scopus citations

• Central role of the NF-κB pathway in the Scgb1a1-expressing epithelium in mediating respiratory syncytial virus-induced airway inflammation

  Tian, B., Yang, J., Zhao, Y., Ivanciuc, T., Sun, H., Wakamiya, M., Garofalo, R. P. & Brasier, A. R., Jun 1 2018, In: Journal of virology. 92, 11, e00441-18.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory syncytial virus
  • Respiratory Syncytial Virus Infections
  • Respiratory Syncytial Viruses
  • Knockout Mice
  • Interferons
  13 Scopus citations

• Cigarette Smoke Condensate Exposure Changes RNA Content of Extracellular Vesicles Released from Small Airway Epithelial Cells

  Corsello, T., Kudlicki, A. S., Garofalo, R. P. & Casola, A., Dec 17 2019, In: Cells. 8, 12

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Vesicles
  • Smoke
  • Tobacco Products
  • Epithelial Cells
  • RNA

• Critical role of TLR4 in human metapneumovirus mediated innate immune responses and disease pathogenesis.

  Velayutham, T. S., Kolli, D., Ivanciuc, T., Garofalo, R. P. & Casola, A., 2013, In: PloS one. 8, 10

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Human metapneumovirus
  • Metapneumovirus
  • Immune System Diseases
  • innate immunity
  • Innate Immunity
  11 Scopus citations

• Cystathionine γ-lyase deficiency enhances airway reactivity and viral-induced disease in mice exposed to side-stream tobacco smoke

  Ivanciuc, T., Sbrana, E., Casola, A. & Garofalo, R. P., Jul 1 2019, In: Pediatric Research. 86, 1, p. 39-46 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystathionine
  • Lyases
  • Smoke
  • Tobacco
  • Virus Diseases
  3 Scopus citations

• Differential response of BDCA-1⁺ and BDCA-3⁺ myeloid dendritic cells to respiratory syncytial virus infection

  Gupta, M. R., Kolli, D. & Garofalo, R. P., Jul 5 2013, In: Respiratory Research. 14, 1, 71.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory Syncytial Virus Infections
  • Myeloid Cells
  • Respiratory Syncytial Viruses
  • Dendritic Cells
  • Cytokines
  15 Scopus citations

• Dynamic conformational switching in the chemokine ligand is essential for G-protein-coupled receptor activation

  Joseph, P. R. B., Sawant, K. V., Isley, A., Pedroza, M., Garofalo, R. P., Richardson, R. M. & Rajarathnam, K., Dec 1 2013, In: Biochemical Journal. 456, 2, p. 241-251 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Proline
  • Glycine
  • G-Protein-Coupled Receptors
  • Chemokines
  • Chemical activation
  20 Scopus citations

• Exchange proteins directly activated by cAMP and their roles in respiratory syncytial virus infection

  Choi, E. J., Ren, Y., Chen, Y., Liu, S., Wu, W., Ren, J., Wang, P., Garofalo, R. P., Zhou, J. & Bao, X., Nov 1 2018, In: Journal of virology. 92, 22, e01200-18.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory syncytial virus
  • Respiratory Syncytial Virus Infections
  • Respiratory Syncytial Viruses
  • infection
  • 3-(5-tert-butylisoxazol-3-yl)-2-((3-chlorophenyl)hydrazono)-3-oxopropionitrile
  3 Scopus citations

• Gestational Exposure to Cigarette Smoke Suppresses the Gasotransmitter H₂S Biogenesis and the Effects Are Transmitted Transgenerationally

  Singh, S. P., Devadoss, D., Manevski, M., Sheybani, A., Ivanciuc, T., Exil, V., Agarwal, H., Raizada, V., Garofalo, R. P., Chand, H. S. & Sopori, M. L., Jul 28 2020, In: Frontiers in immunology. 11, 1628.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gasotransmitters
  • Cystathionine
  • Smoke
  • Tobacco Products
  • Lyases
  2 Scopus citations

• HIF-1α modulates core metabolism and virus replication in primary airway epithelial cells infected with respiratory syncytial virus

  Morris, D. R., Qu, Y., Agrawal, A., Garofalo, R. P. & Casola, A., Oct 2020, In: Viruses. 12, 10, 1088.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hypoxia-Inducible Factor 1
  • Respiratory Syncytial Viruses
  • Virus Replication
  • Respiratory Syncytial Virus Infections
  • endothelial PAS domain-containing protein 1

• Human Metapneumovirus Glycoprotein G Disrupts Mitochondrial Signaling in Airway Epithelial Cells

  Bao, X., Kolli, D., Ren, J., Liu, T., Garofalo, R. P. & Casola, A., Apr 23 2013, In: PloS one. 8, 4, e62568.

  Research output: Contribution to journal › Article › peer-review

  • human metapneumovirus G glycoprotein
  • Human metapneumovirus
  • Epithelial Cells
  • Metapneumovirus
  • Genes
  21 Scopus citations

• Increased Lung Catalase Activity Confers Protection Against Experimental RSV Infection

  Ansar, M., Ivanciuc, T., Garofalo, R. P. & Casola, A., Dec 1 2020, In: Scientific reports. 10, 1, 3653.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • catalase-polyethylene glycol
  • Respiratory Syncytial Virus Infections
  • Respiratory Syncytial Viruses
  • Catalase
  • Lung
  4 Scopus citations

• Lactate dehydrogenase and caspase activity in nasopharyngeal secretions are predictors of bronchiolitis severity

  Mehta, R., Scheffler, M., Tapia, L., Aideyan, L., Patel, K. D., Jewell, A. M., Avadhanula, V., Mei, M., Garofalo, R. P. & Piedra, P. A., Nov 1 2014, In: Influenza and other respiratory viruses. 8, 6, p. 617-625 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bronchiolitis
  • Caspases
  • L-Lactate Dehydrogenase
  • Caspase 3
  • Child
  11 Scopus citations

• Lysines and Arginines play non-redundant roles in mediating chemokine-glycosaminoglycan interactions

  Joseph, P. R. B., Sawant, K. V., Iwahara, J., Garofalo, R. P., Desai, U. R. & Rajarathnam, K., Dec 1 2018, In: Scientific reports. 8, 1, 12289.

  Research output: Contribution to journal › Article › peer-review

  • Glycosaminoglycans
  • Lysine
  • Chemokines
  • Arginine
  • Neutrophils
  3 Scopus citations

• Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: Role of Cxcr2 activation and glycosaminoglycan interactions

  Sawant, K. V., Sepuru, K. M., Lowry, E., Penaranda, B., Frevert, C. W., Garofalo, R. P. & Rajarathnam, K., 2020, (Accepted/In press) In: Journal of Leukocyte Biology.

  Research output: Contribution to journal › Article › peer-review

  • Neutrophil Infiltration
  • Glycosaminoglycans
  • Chemokines
  • Personnel Selection
  • Neutrophil Activation

• Pancreatitis activates pancreatic apelin-APJ axis in mice

  Han, S., Englander, E. W., Gomez, G. A., Aronson, J. F., Rastellini, C., Garofalo, R. P., Kolli, D., Quertermous, T., Kundu, R. & Greeley, G. H., Jul 15 2013, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 305, 2, p. G139-G150

  Research output: Contribution to journal › Article › peer-review

  • Apelin
  • Pancreatitis
  • Pancreatic Stellate Cells
  • Chronic Pancreatitis
  • Fibrosis
  11 Scopus citations

• Paramyxovirus infection regulates T cell responses by BDCA-1⁺and BDCA-3⁺ myeloid dendritic cells

  Gupta, M. R., Kolli, D., Molteni, C., Casola, A. & Garofalo, R. P., Jun 11 2014, In: PloS one. 9, 6, e99227.

  Research output: Contribution to journal › Article › peer-review

  • Human metapneumovirus
  • Dendritic Cells
  • Respiratory syncytial virus
  • T-cells
  • Metapneumovirus
  5 Scopus citations

• Proinflammatory effects of respiratory syncytial virus-induced epithelial HMGB1 on human innate immune cell activation

  Rayavara, K., Kurosky, A., Stafford, S. J., Garg, N. J., Brasier, A. R., Garofalo, R. P. & Hosakote, Y. M., Nov 1 2018, In: Journal of Immunology. 201, 9, p. 2832-2841 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory Syncytial Viruses
  • p38 Mitogen-Activated Protein Kinases
  • Epithelial Cells
  • Chemokines
  • Cytokines
  8 Scopus citations

• Proline substitution of dimer interface β-strand residues as a strategy for the design of functional monomeric proteins

  Joseph, P. R. B., Poluri, K. M., Gangavarapu, P., Rajagopalan, L., Raghuwanshi, S., Richardson, R. M., Garofalo, R. P. & Rajarathnam, K., Sep 17 2013, In: Biophysical journal. 105, 6, p. 1491-1501 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Proline
  • Proteins
  • Catalysis
  • Amides
  • Static Electricity
  19 Scopus citations

• Protective role of nuclear factor erythroid 2-related factor 2 against respiratory syncytial virus and human metapneumovirus infections

  Ivanciuc, T., Sbrana, E., Casola, A. & Garofalo, R. P., Apr 23 2018, In: Frontiers in immunology. 9, APR, 854.

  Research output: Contribution to journal › Article › peer-review

  • Metapneumovirus
  • Respiratory Syncytial Viruses
  • Antioxidants
  • Airway Obstruction
  • Enzymes
  9 Scopus citations

• Respiratory syncytial virus infection induces chromatin remodeling to activate growth factor and extracellular matrix secretion pathways

  Xu, X., Qiao, D., Mann, M., Garofalo, R. P. & Brasier, A. R., Aug 2020, In: Viruses. 12, 8, 804.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Respiratory Syncytial Virus Infections
  • Chromatin Assembly and Disassembly
  • Secretory Pathway
  • Chromatin
  • Extracellular Matrix
  1 Scopus citations

• Selective blockade of TNFR1 improves clinical disease and bronchoconstriction in experimental RSV infection

  Morris, D. R., Ansar, M., Ivanciuc, T., Qu, Y., Casola, A. & Garofalo, R. P., Oct 17 2020, In: Viruses. 12, 10, 1176.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Receptors, Tumor Necrosis Factor, Type I
  • Respiratory Syncytial Virus Infections
  • Bronchoconstriction
  • Respiratory Syncytial Viruses
  • Receptors, Tumor Necrosis Factor, Type II

• The monomer-dimer equilibrium and glycosaminoglycan interactions of chemokine CXCL8 regulate tissue-specific neutrophil recruitment

  Gangavarapu, P., Rajagopalan, L., Kolli, D., Guerrero-Plata, A., Garofalo, R. P. & Rajarathnam, K., Feb 2012, In: Journal of Leukocyte Biology. 91, 2, p. 259-265 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Neutrophil Infiltration
  • Glycosaminoglycans
  • Interleukin-8
  • Chemokines
  • Peritoneum
  62 Scopus citations
• Comment/debate

  Corrigendum to "MyD88 controls human metapneumovirus-induced pulmonary immune responses and disease pathogenesis" [Virus Res. 176 (1-2) (2013) 241-250]

  Ren, J., Kolli, D., Deng, J., Fang, R., Gong, B., Xue, M., Casola, A., Garofalo, R. P., Wang, T. & Bao, X., Nov 6 2013, In: Virus Research. 177, 2, 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review
• Review article

  Respiratory syncytial virus infection: Mechanisms of redox control and novel therapeutic opportunities

  Garofalo, R. P., Kolli, D. & Casola, A., Jan 10 2013, In: Antioxidants and Redox Signaling. 18, 2, p. 186-217 32 p.

  Research output: Contribution to journal › Review article › peer-review

  • Oxidation-Reduction
  • Respiratory Syncytial Virus Infections
  • Respiratory Syncytial Viruses
  • Viruses
  • Oxidative stress
  47 Scopus citations