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  • Alexander Bukreyev
2018

Staufen1 interacts with multiple components of the ebola virus ribonucleoprotein and enhances viral RNA synthesis

Fang, J., Pietzsch, C., Ramanathan, P., Santos, R. I., Ilinykh, P. A., Garcia-Blanco, M. A., Bukreyev, A. & Bradrick, S. S., Sep 1 2018, In : mBio. 9, 5, e01771-18.

Research output: Contribution to journalArticle

3 Scopus citations

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

the Viral Hemorrhagic Fever Immunotherapeutic Consortium, Aug 9 2018, In : Cell. 174, 4, p. 938-952.e13

Research output: Contribution to journalArticle

54 Scopus citations

Taxonomy of the order Mononegavirales: update 2018

Amarasinghe, G. K., Aréchiga Ceballos, N. G., Banyard, A. C., Basler, C. F., Bavari, S., Bennett, A. J., Blasdell, K. R., Briese, T., Bukreyev, A., Caì, Y., Calisher, C. H., Campos Lawson, C., Chandran, K., Chapman, C. A., Chiu, C. Y., Choi, K. S., Collins, P. L., Dietzgen, R. G., Dolja, V. V., Dolnik, O. & 71 others, Domier, L. L., Dürrwald, R., Dye, J. M., Easton, A. J., Ebihara, H., Echevarría, J. E., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freuling, C. M., Ghedin, E., Goldberg, T. L., Hewson, R., Horie, M., Hyndman, T. H., Jiāng, D., Kityo, R., Kobinger, G. P., Kondō, H., Koonin, E. V., Krupovic, M., Kurath, G., Lamb, R. A., Lee, B., Leroy, E. M., Maes, P., Maisner, A., Marston, D. A., Mor, S. K., Müller, T., Mühlberger, E., Ramírez, V. M. N., Netesov, S. V., Ng, T. F. F., Nowotny, N., Palacios, G., Patterson, J. L., Pawęska, J. T., Payne, S. L., Prieto, K., Rima, B. K., Rota, P., Rubbenstroth, D., Schwemmle, M., Siddell, S., Smither, S. J., Song, Q., Song, T., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Thomazelli, L. M., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Vázquez-Morón, S., Verdugo, C., Volchkov, V. E., Wahl, V., Walker, P. J., Wang, D., Wang, L. F., Wellehan, J. F. X., Wiley, M. R., Whitfield, A. E., Wolf, Y. I., Yè, G., Zhāng, Y. Z. & Kuhn, J. H., Aug 1 2018, In : Archives of virology. 163, 8, p. 2283-2294 12 p.

Research output: Contribution to journalArticle

77 Scopus citations

The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding

King, L. B., Fusco, M. L., Flyak, A. I., Ilinykh, P. A., Huang, K., Gunn, B., Kirchdoerfer, R. N., Hastie, K. M., Sangha, A. K., Meiler, J., Alter, G., Bukreyev, A., Crowe, J. E. & Saphire, E. O., Jan 10 2018, In : Cell Host and Microbe. 23, 1, p. 101-109.e4

Research output: Contribution to journalArticle

10 Scopus citations
2019

Antibody-mediated protective mechanisms induced by a trivalent parainfluenza virus-vectored ebolavirus vaccine

Brian Kimble, J., Malherbe, D. C., Meyer, M., Gunn, B. M., Karim, M. M., Ilinykh, P. A., Iampietro, M., Mohamed, K. S., Negi, S., Gilchuk, P., Huang, K., Wolf, Y. I., Braun, W., Crowe, J. E., Alter, G. & Bukreyev, A., Feb 1 2019, In : Journal of virology. 93, 4, e0184518.

Research output: Contribution to journalArticle

1 Scopus citations

Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk

King, L. B., West, B. R., Moyer, C. L., Gilchuk, P., Flyak, A., Ilinykh, P. A., Bombardi, R., Hui, S., Huang, K., Bukreyev, A., Crowe, J. E. & Saphire, E. O., Dec 1 2019, In : Nature communications. 10, 1, 1788.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection

Younan, P., Santos, R. I., Ramanathan, P., Iampietro, M., Nishida, A., Dutta, M., Ammosova, T., Meyer, M., Katze, M. G., Popov, V. L., Nekhai, S. & Bukreyev, A., 2019, In : PLoS pathogens. 15, 10, e1008068.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

ICTV virus taxonomy profile: Filoviridae

ICTV Report Consortium, Jun 2019, In : Journal of General Virology. 100, 6, p. 911-912 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

Structural basis of broad ebolavirus neutralization by a human survivor antibody

West, B. R., Wec, A. Z., Moyer, C. L., Fusco, M. L., Ilinykh, P. A., Huang, K., Wirchnianski, A. S., James, R. M., Herbert, A. S., Hui, S., Goodwin, E., Howell, K. A., Kailasan, S., Aman, M. J., Walker, L. M., Dye, J. M., Bukreyev, A., Chandran, K. & Saphire, E. O., Mar 1 2019, In : Nature Structural and Molecular Biology. 26, 3, p. 204-212 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition

Lin, X., Ammosova, T., Choy, M. S., Pietzsch, C. A., Ivanov, A., Ahmad, A., Saygideğer, Y., Kumari, N., Kovalskyy, D., Üren, A., Peti, W., Bukreyev, A. & Nekhai, S., Sep 13 2019, In : Frontiers in Microbiology. 10, 2145.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Taxonomy of the order Mononegavirales: second update 2018

Maes, P., Amarasinghe, G. K., Ayllón, M. A., Basler, C. F., Bavari, S., Blasdell, K. R., Briese, T., Brown, P. A., Bukreyev, A., Balkema-Buschmann, A., Buchholz, U. J., Chandran, K., Crozier, I., de Swart, R. L., Dietzgen, R. G., Dolnik, O., Domier, L. L., Drexler, J. F., Dürrwald, R., Dundon, W. G. & 57 others, Duprex, W. P., Dye, J. M., Easton, A. J., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freitas-Astúa, J., Ghedin, E., Griffiths, A., Hewson, R., Horie, M., Hurwitz, J. L., Hyndman, T. H., Jiāng, D., Kobinger, G. P., Kondō, H., Kurath, G., Kuzmin, I. V., Lamb, R. A., Lee, B., Leroy, E. M., Lǐ, J., Marzano, S. Y. L., Mühlberger, E., Netesov, S. V., Nowotny, N., Palacios, G., Pályi, B., Pawęska, J. T., Payne, S. L., Rima, B. K., Rota, P., Rubbenstroth, D., Simmonds, P., Smither, S. J., Song, Q., Song, T., Spann, K., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., van den Hoogen, B., Vasilakis, N., Wahl, V., Walker, P. J., Wang, D., Wang, L. F., Whitfield, A. E., Williams, J. V., Yè, G., Zerbini, F. M., Zhang, Y. Z. & Kuhn, J. H., Apr 3 2019, In : Archives of virology. 164, 4, p. 1233-1244 12 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Taxonomy of the order Mononegavirales: update 2019

Amarasinghe, G. K., Ayllón, M. A., Bào, Y., Basler, C. F., Bavari, S., Blasdell, K. R., Briese, T., Brown, P. A., Bukreyev, A., Balkema-Buschmann, A., Buchholz, U. J., Chabi-Jesus, C., Chandran, K., Chiapponi, C., Crozier, I., de Swart, R. L., Dietzgen, R. G., Dolnik, O., Drexler, J. F., Dürrwald, R. & 64 others, Dundon, W. G., Duprex, W. P., Dye, J. M., Easton, A. J., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freitas-Astúa, J., Griffiths, A., Hewson, R., Horie, M., Hyndman, T. H., Jiāng, D., Kitajima, E. W., Kobinger, G. P., Kondō, H., Kurath, G., Kuzmin, I. V., Lamb, R. A., Lavazza, A., Lee, B., Lelli, D., Leroy, E. M., Lǐ, J., Maes, P., Marzano, S. Y. L., Moreno, A., Mühlberger, E., Netesov, S. V., Nowotny, N., Nylund, A., Økland, A. L., Palacios, G., Pályi, B., Pawęska, J. T., Payne, S. L., Prosperi, A., Ramos-González, P. L., Rima, B. K., Rota, P., Rubbenstroth, D., Shī, M., Simmonds, P., Smither, S. J., Sozzi, E., Spann, K., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., van den Hoogen, B., Vasilakis, N., Wahl, V., Walker, P. J., Wang, L. F., Whitfield, A. E., Williams, J. V., Zerbini, F. M., Zhāng, T., Zhang, Y. Z. & Kuhn, J. H., Jul 1 2019, In : Archives of virology. 164, 7, p. 1967-1980 14 p.

Research output: Contribution to journalArticle

Open Access
47 Scopus citations
2020

Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization

Gilchuk, P., Murin, C. D., Milligan, J. C., Cross, R. W., Mire, C. E., Ilinykh, P. A., Huang, K., Kuzmina, N., Altman, P. X., Hui, S., Gunn, B. M., Bryan, A. L., Davidson, E., Doranz, B. J., Turner, H. L., Alkutkar, T., Flinko, R., Orlandi, C., Carnahan, R., Nargi, R. & 13 others, Bombardi, R. G., Vodzak, M. E., Li, S., Okoli, A., Ibeawuchi, M., Ohiaeri, B., Lewis, G. K., Alter, G., Bukreyev, A., Saphire, E. O., Geisbert, T. W., Ward, A. B. & Crowe, J. E., Feb 18 2020, In : Immunity. 52, 2, p. 388-403.e12

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Ebola virus produces discrete small noncoding RNAs independently of the host MicroRNA pathway which lack RNA interference activity in bat and human cells

Prasad, A., Ronk, A. J., Widen, S. G., Wood, T. G., Basler, C. F. & Bukreyev, A., Mar 1 2020, In : Journal of virology. 94, 6, e01441-19.

Research output: Contribution to journalArticle

2 Scopus citations

Global phosphoproteomic analysis of Ebola virions reveals a novel role for VP35 phosphorylation-dependent regulation of genome transcription

Ivanov, A., Ramanathan, P., Parry, C., Ilinykh, P. A., Lin, X., Petukhov, M., Obukhov, Y., Ammosova, T., Amarasinghe, G. K., Bukreyev, A. & Nekhai, S., Jul 1 2020, In : Cellular and Molecular Life Sciences. 77, 13, p. 2579-2603 25 p.

Research output: Contribution to journalArticle

Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies

Ilinykh, P. A., Huang, K., Santos, R. I., Gilchuk, P., Gunn, B. M., Karim, M. M., Liang, J., Fouch, M. E., Davidson, E., Parekh, D. V., Kimble, J. B., Pietzsch, C. A., Meyer, M., Kuzmina, N. A., Zeitlin, L., Saphire, E. O., Alter, G., Crowe, J. E. & Bukreyev, A., Jun 10 2020, In : Cell Host and Microbe. 27, 6, p. 976-991.e11

Research output: Contribution to journalArticle

1 Scopus citations

Small Molecule Compounds That Inhibit Antioxidant Response Gene Expression in an Inducer-Dependent Manner

Edwards, M. R., Liu, G., De, S., Sourimant, J., Pietzsch, C., Johnson, B., Amarasinghe, G. K., Leung, D. W., Bukreyev, A., Plemper, R. K., Aron, Z., Bowlin, T. L., Moir, D. T. & Basler, C. F., Mar 13 2020, In : ACS Infectious Diseases. 6, 3, p. 489-502 14 p.

Research output: Contribution to journalArticle