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  • Alexander Bukreyev

Staufen1 interacts with multiple components of the ebola virus ribonucleoprotein and enhances viral RNA synthesis

Fang, J., Pietzsch, C., Ramanathan, P., Santos, R. I., Ilinykh, P. A., Garcia-Blanco, M. A., Bukreyev, A. & Bradrick, S. S., Sep 1 2018, In : mBio. 9, 5, e01771-18.

Research output: Contribution to journalArticle

4 Scopus citations

Structural basis of broad ebolavirus neutralization by a human survivor antibody

West, B. R., Wec, A. Z., Moyer, C. L., Fusco, M. L., Ilinykh, P. A., Huang, K., Wirchnianski, A. S., James, R. M., Herbert, A. S., Hui, S., Goodwin, E., Howell, K. A., Kailasan, S., Aman, M. J., Walker, L. M., Dye, J. M., Bukreyev, A., Chandran, K. & Saphire, E. O., Mar 1 2019, In : Nature Structural and Molecular Biology. 26, 3, p. 204-212 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

the Viral Hemorrhagic Fever Immunotherapeutic Consortium, Aug 9 2018, In : Cell. 174, 4, p. 938-952.e13

Research output: Contribution to journalArticle

58 Scopus citations

Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition

Lin, X., Ammosova, T., Choy, M. S., Pietzsch, C. A., Ivanov, A., Ahmad, A., Saygideğer, Y., Kumari, N., Kovalskyy, D., Üren, A., Peti, W., Bukreyev, A. & Nekhai, S., Sep 13 2019, In : Frontiers in Microbiology. 10, 2145.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Taxonomy of the order Mononegavirales: update 2017

Amarasinghe, G. K., Bào, Y., Basler, C. F., Bavari, S., Beer, M., Bejerman, N., Blasdell, K. R., Bochnowski, A., Briese, T., Bukreyev, A., Calisher, C. H., Chandran, K., Collins, P. L., Dietzgen, R. G., Dolnik, O., Dürrwald, R., Dye, J. M., Easton, A. J., Ebihara, H., Fang, Q. & 53 others, Formenty, P., Fouchier, R. A. M., Ghedin, E., Harding, R. M., Hewson, R., Higgins, C. M., Hong, J., Horie, M., James, A. P., Jiāng, D., Kobinger, G. P., Kondo, H., Kurath, G., Lamb, R. A., Lee, B., Leroy, E. M., Li, M., Maisner, A., Mühlberger, E., Netesov, S. V., Nowotny, N., Patterson, J. L., Payne, S. L., Paweska, J. T., Pearson, M. N., Randall, R. E., Revill, P. A., Rima, B. K., Rota, P., Rubbenstroth, D., Schwemmle, M., Smither, S. J., Song, Q., Stone, D. M., Takada, A., Terregino, C., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Volchkov, V. E., Wahl-Jensen, V., Walker, P. J., Wang, B., Wang, D., Wang, F., Wang, L. F., Werren, J. H., Whitfield, A. E., Yan, Z., Ye, G. & Kuhn, J. H., Aug 1 2017, In : Archives of virology. 162, 8, p. 2493-2504 12 p.

Research output: Contribution to journalArticle

124 Scopus citations

Taxonomy of the order Mononegavirales: second update 2018

Maes, P., Amarasinghe, G. K., Ayllón, M. A., Basler, C. F., Bavari, S., Blasdell, K. R., Briese, T., Brown, P. A., Bukreyev, A., Balkema-Buschmann, A., Buchholz, U. J., Chandran, K., Crozier, I., de Swart, R. L., Dietzgen, R. G., Dolnik, O., Domier, L. L., Drexler, J. F., Dürrwald, R., Dundon, W. G. & 57 others, Duprex, W. P., Dye, J. M., Easton, A. J., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freitas-Astúa, J., Ghedin, E., Griffiths, A., Hewson, R., Horie, M., Hurwitz, J. L., Hyndman, T. H., Jiāng, D., Kobinger, G. P., Kondō, H., Kurath, G., Kuzmin, I. V., Lamb, R. A., Lee, B., Leroy, E. M., Lǐ, J., Marzano, S. Y. L., Mühlberger, E., Netesov, S. V., Nowotny, N., Palacios, G., Pályi, B., Pawęska, J. T., Payne, S. L., Rima, B. K., Rota, P., Rubbenstroth, D., Simmonds, P., Smither, S. J., Song, Q., Song, T., Spann, K., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., van den Hoogen, B., Vasilakis, N., Wahl, V., Walker, P. J., Wang, D., Wang, L. F., Whitfield, A. E., Williams, J. V., Yè, G., Zerbini, F. M., Zhang, Y. Z. & Kuhn, J. H., Apr 3 2019, In : Archives of virology. 164, 4, p. 1233-1244 12 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Taxonomy of the order Mononegavirales: update 2016

Afonso, C. L., Amarasinghe, G. K., Bányai, K., Bào, Y., Basler, C. F., Bavari, S., Bejerman, N., Blasdell, K. R., Briand, F. X., Briese, T., Bukreyev, A., Calisher, C. H., Chandran, K., Chéng, J., Clawson, A. N., Collins, P. L., Dietzgen, R. G., Dolnik, O., Domier, L. L., Dürrwald, R. & 63 others, Dye, J. M., Easton, A. J., Ebihara, H., Farkas, S. L., Freitas-Astúa, J., Formenty, P., Fouchier, R. A. M., Fù, Y., Ghedin, E., Goodin, M. M., Hewson, R., Horie, M., Hyndman, T. H., Jiāng, D., Kitajima, E. W., Kobinger, G. P., Kondo, H., Kurath, G., Lamb, R. A., Lenardon, S., Leroy, E. M., Li, C. X., Lin, X. D., Liú, L., Longdon, B., Marton, S., Maisner, A., Mühlberger, E., Netesov, S. V., Nowotny, N., Patterson, J. L., Payne, S. L., Paweska, J. T., Randall, R. E., Rima, B. K., Rota, P., Rubbenstroth, D., Schwemmle, M., Shi, M., Smither, S. J., Stenglein, M. D., Stone, D. M., Takada, A., Terregino, C., Tesh, R. B., Tian, J. H., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Verbeek, M., Volchkov, V. E., Wahl-Jensen, V., Walsh, J. A., Walker, P. J., Wang, D., Wang, L. F., Wetzel, T., Whitfield, A. E., Xiè, J., Yuen, K. Y., Zhang, Y. Z. & Kuhn, J. H., Aug 1 2016, In : Archives of virology. 161, 8, p. 2351-2360 10 p.

Research output: Contribution to journalArticle

251 Scopus citations

Taxonomy of the order Mononegavirales: update 2018

Amarasinghe, G. K., Aréchiga Ceballos, N. G., Banyard, A. C., Basler, C. F., Bavari, S., Bennett, A. J., Blasdell, K. R., Briese, T., Bukreyev, A., Caì, Y., Calisher, C. H., Campos Lawson, C., Chandran, K., Chapman, C. A., Chiu, C. Y., Choi, K. S., Collins, P. L., Dietzgen, R. G., Dolja, V. V., Dolnik, O. & 71 others, Domier, L. L., Dürrwald, R., Dye, J. M., Easton, A. J., Ebihara, H., Echevarría, J. E., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freuling, C. M., Ghedin, E., Goldberg, T. L., Hewson, R., Horie, M., Hyndman, T. H., Jiāng, D., Kityo, R., Kobinger, G. P., Kondō, H., Koonin, E. V., Krupovic, M., Kurath, G., Lamb, R. A., Lee, B., Leroy, E. M., Maes, P., Maisner, A., Marston, D. A., Mor, S. K., Müller, T., Mühlberger, E., Ramírez, V. M. N., Netesov, S. V., Ng, T. F. F., Nowotny, N., Palacios, G., Patterson, J. L., Pawęska, J. T., Payne, S. L., Prieto, K., Rima, B. K., Rota, P., Rubbenstroth, D., Schwemmle, M., Siddell, S., Smither, S. J., Song, Q., Song, T., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Thomazelli, L. M., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Vázquez-Morón, S., Verdugo, C., Volchkov, V. E., Wahl, V., Walker, P. J., Wang, D., Wang, L. F., Wellehan, J. F. X., Wiley, M. R., Whitfield, A. E., Wolf, Y. I., Yè, G., Zhāng, Y. Z. & Kuhn, J. H., Aug 1 2018, In : Archives of virology. 163, 8, p. 2283-2294 12 p.

Research output: Contribution to journalArticle

80 Scopus citations

Taxonomy of the order Mononegavirales: update 2019

Amarasinghe, G. K., Ayllón, M. A., Bào, Y., Basler, C. F., Bavari, S., Blasdell, K. R., Briese, T., Brown, P. A., Bukreyev, A., Balkema-Buschmann, A., Buchholz, U. J., Chabi-Jesus, C., Chandran, K., Chiapponi, C., Crozier, I., de Swart, R. L., Dietzgen, R. G., Dolnik, O., Drexler, J. F., Dürrwald, R. & 64 others, Dundon, W. G., Duprex, W. P., Dye, J. M., Easton, A. J., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freitas-Astúa, J., Griffiths, A., Hewson, R., Horie, M., Hyndman, T. H., Jiāng, D., Kitajima, E. W., Kobinger, G. P., Kondō, H., Kurath, G., Kuzmin, I. V., Lamb, R. A., Lavazza, A., Lee, B., Lelli, D., Leroy, E. M., Lǐ, J., Maes, P., Marzano, S. Y. L., Moreno, A., Mühlberger, E., Netesov, S. V., Nowotny, N., Nylund, A., Økland, A. L., Palacios, G., Pályi, B., Pawęska, J. T., Payne, S. L., Prosperi, A., Ramos-González, P. L., Rima, B. K., Rota, P., Rubbenstroth, D., Shī, M., Simmonds, P., Smither, S. J., Sozzi, E., Spann, K., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., van den Hoogen, B., Vasilakis, N., Wahl, V., Walker, P. J., Wang, L. F., Whitfield, A. E., Williams, J. V., Zerbini, F. M., Zhāng, T., Zhang, Y. Z. & Kuhn, J. H., Jul 1 2019, In : Archives of virology. 164, 7, p. 1967-1980 14 p.

Research output: Contribution to journalArticle

Open Access
48 Scopus citations

The Ebola Interferon Inhibiting Domains Attenuate and Dysregulate Cell-Mediated Immune Responses

Lubaki, N. M., Younan, P., Santos, R. I., Meyer, M., Iampietro, M., Koup, R. A. & Bukreyev, A., Dec 8 2016, In : PLoS pathogens. 12, 12, e1006031.

Research output: Contribution to journalArticle

18 Scopus citations

The human respiratory syncytial virus nonstructural protein 1 regulates type I and type II interferon pathways

Hastie, M. L., Headlam, M. J., Patel, N. B., Bukreyev, A. A., Buchholz, U. J., Dave, K. A., Norris, E. L., Wright, C. L., Spann, K. M., Collins, P. L. & Gorman, J. J., May 2012, In : Molecular and Cellular Proteomics. 11, 5, p. 108-127 20 p.

Research output: Contribution to journalArticle

38 Scopus citations

The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains

Lubaki, N. M., Ilinykh, P., Pietzsch, C., Tigabu, B., Freiberg, A. N., Koup, R. A. & Bukreyev, A., 2013, In : Journal of virology. 87, 22, p. 12506 1 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding

King, L. B., Fusco, M. L., Flyak, A. I., Ilinykh, P. A., Huang, K., Gunn, B., Kirchdoerfer, R. N., Hastie, K. M., Sangha, A. K., Meiler, J., Alter, G., Bukreyev, A., Crowe, J. E. & Saphire, E. O., Jan 10 2018, In : Cell Host and Microbe. 23, 1, p. 101-109.e4

Research output: Contribution to journalArticle

10 Scopus citations

The secreted g protein of human respiratory syncytial virus antagonizes antibody-mediated restriction of replication involving macrophages and complement

Bukreyev, A., Yang, L. & Collins, P. L., Oct 2012, In : Journal of virology. 86, 19, p. 10880-10884 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation

Rialdi, A., Campisi, L., Zhao, N., Lagda, A. C., Pietzsch, C., Ho, J. S. Y., Martinez-Gil, L., Fenouil, R., Chen, X., Edwards, M., Metreveli, G., Jordan, S., Peralta, Z., Munoz-Fontela, C., Bouvier, N., Merad, M., Jin, J., Weirauch, M., Heinz, S., Benner, C. & 5 others, Van Bakel, H., Basler, C., García-Sastre, A., Bukreyev, A. & Marazzi, I., May 27 2016, In : Science. 352, 6289, 7993.

Research output: Contribution to journalArticle

63 Scopus citations

Topoisomerase II inhibitors induce DNA damage-dependent interferon responses circumventing ebola virus immune evasion

Luthra, P., Aguirre, S., Yen, B. C., Pietzsch, C. A., Sanchez-Aparicio, M. T., Tigabu, B., Morlock, L. K., García-Sastre, A., Leung, D. W., Williams, N. S., Fernandez-Sesma, A., Bukreyev, A. & Basler, C. F., Mar 1 2017, In : mBio. 8, 2, e00368-17.

Research output: Contribution to journalArticle

33 Scopus citations

Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses

Kambham, R., Hirano, M., Fagg, W. S., McAnarney, E. T., Shan, C., Xie, X., Hage, A., Pietzsch, C. A., Bukreyev, A., Rajsbaum Gorodezky, R., Shi, P. Y., Bedford, M. T., Bradrick, S., Menachery, V. & Garcia-Blanco, M., Oct 2020, In : Antiviral research. 182, 104874.

Research output: Contribution to journalArticle

Open Access

Virus nomenclature below the species level: A standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae

Kuhn, J. H., Bao, Y., Bavari, S., Becker, S., Bradfute, S., Brister, J. R., Bukreyev, A. A., Caì, Y., Chandran, K., Davey, R. A., Dolnik, O., Dye, J. M., Enterlein, S., Gonzalez, J. P., Formenty, P., Freiberg, A. N., Hensley, L. E., Honko, A. N., Ignatyev, G. M., Jahrling, P. B. & 30 others, Johnson, K. M., Klenk, H. D., Kobinger, G., Lackemeyer, M. G., Leroy, E. M., Lever, M. S., Lofts, L. L., Mühlberger, E., Netesov, S. V., Olinger, G. G., Palacios, G., Patterson, J. L., Paweska, J. T., Pitt, L., Radoshitzky, S. R., Ryabchikova, E. I., Saphire, E. O., Shestopalov, A. M., Smither, S. J., Sullivan, N. J., Swanepoel, R., Takada, A., Towner, J. S., van der Groen, G., Volchkov, V. E., Wahl-Jensen, V., Warren, T. K., Warfield, K. L., Weidmann, M. & Nichol, S. T., Jun 2013, In : Archives of virology. 158, 6, p. 1425-1432 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Virus nomenclature below the species level: A standardized nomenclature for natural variants of viruses assigned to the family Filoviridae

Kuhn, J. H., Bao, Y., Bavari, S., Becker, S., Bradfute, S., Brister, J. R., Bukreyev, A. A., Chandran, K., Davey, R. A., Dolnik, O., Dye, J. M., Enterlein, S., Hensley, L. E., Honko, A. N., Jahrling, P. B., Johnson, K. M., Kobinger, G., Leroy, E. M., Lever, M. S., Mühlberger, E. & 17 others, Netesov, S. V., Olinger, G. G., Palacios, G., Patterson, J. L., Paweska, J. T., Pitt, L., Radoshitzky, S. R., Saphire, E. O., Smither, S. J., Swanepoel, R., Towner, J. S., van der Groen, G., Volchkov, V. E., Wahl-Jensen, V., Warren, T. K., Weidmann, M. & Nichol, S. T., Jan 1 2013, In : Archives of virology. 158, 1, p. 301-311 11 p.

Research output: Contribution to journalArticle

68 Scopus citations

Virus nomenclature below the species level: A standardized nomenclature for filovirus strains and variants rescued from cDNA

Kuhn, J. H., Bào, Y., Bavari, S., Becker, S., Bradfute, S., Brauburger, K., Rodney Brister, J., Bukreyev, A. A., Caì, Y., Chandran, K., Davey, R. A., Dolnik, O., Dye, J. M., Enterlein, S., Gonzalez, J. P., Formenty, P., Freiberg, A. N., Hensley, L. E., Hoenen, T., Honko, A. N. & 32 others, Ignatyev, G. M., Jahrling, P. B., Johnson, K. M., Klenk, H. D., Kobinger, G., Lackemeyer, M. G., Leroy, E. M., Lever, M. S., Mühlberger, E., Netesov, S. V., Olinger, G. G., Palacios, G., Patterson, J. L., Paweska, J. T., Pitt, L., Radoshitzky, S. R., Ryabchikova, E. I., Saphire, E. O., Shestopalov, A. M., Smither, S. J., Sullivan, N. J., Swanepoel, R., Takada, A., Towner, J. S., van der Groen, G., Volchkov, V. E., Volchkova, V. A., Wahl-Jensen, V., Warren, T. K., Warfield, K. L., Weidmann, M. & Nichol, S. T., May 2014, In : Archives of virology. 159, 5, p. 1229-1237 9 p.

Research output: Contribution to journalArticle

52 Scopus citations