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  • Alexander Bukreyev
2016

The Ebola Interferon Inhibiting Domains Attenuate and Dysregulate Cell-Mediated Immune Responses

Lubaki, N. M., Younan, P., Santos, R. I., Meyer, M., Iampietro, M., Koup, R. A. & Bukreyev, A., Dec 8 2016, In : PLoS pathogens. 12, 12, e1006031.

Research output: Contribution to journalArticle

18 Scopus citations

Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation

Rialdi, A., Campisi, L., Zhao, N., Lagda, A. C., Pietzsch, C., Ho, J. S. Y., Martinez-Gil, L., Fenouil, R., Chen, X., Edwards, M., Metreveli, G., Jordan, S., Peralta, Z., Munoz-Fontela, C., Bouvier, N., Merad, M., Jin, J., Weirauch, M., Heinz, S., Benner, C. & 5 others, Van Bakel, H., Basler, C., García-Sastre, A., Bukreyev, A. & Marazzi, I., May 27 2016, In : Science. 352, 6289, 7993.

Research output: Contribution to journalArticle

63 Scopus citations
2015

Adapting high-throughput screening methods and assays for biocontainment laboratories

Rasmussen, L., Tigabu, B., White, E. L., Bostwick, R., Tower, N., Bukreyev, A., Rockx, B., Leduc, J. W. & Noah, J. W., Feb 1 2015, In : Assay and Drug Development Technologies. 13, 1, p. 44-54 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Aerosolized Ebola vaccine protects primates and elicits lung-resident T cell responses

Meyer, M., Garron, T., Lubaki, N. M., Mire, C. E., Fenton, K. A., Klages, C., Olinger, G. G., Geisbert, T. W., Collins, P. L. & Bukreyev, A., Aug 3 2015, In : Journal of Clinical Investigation. 125, 8, p. 3241-3255 15 p.

Research output: Contribution to journalArticle

44 Scopus citations

Different temporal effects of Ebola virus VP35 and VP24 proteins on global gene expression in human dendritic cells

Ilinykh, P. A., Lubaki, N. M., Widen, S., Renn, L. A., Theisen, T. C., Rabin, R. L., Wood, T. & Bukreyev, A., 2015, In : Journal of Virology. 89, 15, p. 7567-7583 17 p.

Research output: Contribution to journalArticle

32 Scopus citations

Mechanism of Human Antibody-Mediated Neutralization of Marburg Virus

Flyak, A. I., Ilinykh, P. A., Murin, C. D., Garron, T., Shen, X., Fusco, M. L., Hashiguchi, T., Bornholdt, Z. A., Slaughter, J. C., Sapparapu, G., Klages, C., Ksiazek, T. G., Ward, A. B., Saphire, E. O., Bukreyev, A. & Crowe, J. E., Feb 26 2015, In : Cell. 160, 5, p. 893-903 11 p.

Research output: Contribution to journalArticle

77 Scopus citations

Partial attenuation of respiratory syncytial virus with a deletion of a small hydrophobic gene is associated with elevated interleukin-1β responses

Russell, R. F., McDonald, J. U., Ivanova, M., Zhong, Z., Bukreyev, A. & Tregoning, J. S., 2015, In : Journal of virology. 89, 17, p. 8974-8981 8 p.

Research output: Contribution to journalArticle

29 Scopus citations
2014

A BSL-4 high-throughput screen identifies sulfonamide inhibitors of Nipah virus

Tigabu, B., Rasmussen, L., White, E. L., Tower, N., Saeed, M., Bukreyev, A., Rockx, B., Leduc, J. W. & Noah, J. W., Apr 1 2014, In : Assay and Drug Development Technologies. 12, 3, p. 155-161 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

A comprehensive proteomic view of responses of A549 type II alveolar epithelial cells to human respiratory syncytial virus infection

Dave, K. A., Norris, E. L., Bukreyev, A. A., Headlam, M. J., Buchholz, U. J., Singh, T., Collins, P. L. & Gorman, J. J., Dec 1 2014, In : Molecular and Cellular Proteomics. 13, 12, p. 3250-3269 20 p.

Research output: Contribution to journalArticle

22 Scopus citations

Discussions and decisions of the 2012-2014 International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group, January 2012-June 2013

Bukreyev, A. A., Chandran, K., Dolnik, O., Dye, J. M., Ebihara, H., Leroy, E. M., Mühlberger, E., Netesov, S. V., Patterson, J. L., Paweska, J. T., Saphire, E. O., Smither, S. J., Takada, A., Towner, J. S., Volchkov, V. E., Warren, T. K. & Kuhn, J. H., Apr 2014, In : Archives of virology. 159, 4, p. 821-830 10 p.

Research output: Contribution to journalArticle

62 Scopus citations

Filovirus refseq entries: Evaluation and selection of filovirus type variants, Type sequences, And names

Kuhn, J. H., Andersen, K. G., Bào, Y., Bavari, S., Becker, S., Bennett, R. S., Bergman, N. H., Blinkova, O., Bradfute, S., Rodney Brister, J., Bukreyev, A., Chandran, K., Chepurnov, A. A., Davey, R. A., Dietzgen, R. G., Doggett, N. A., Dolnik, O., Dye, J. M., Enterlein, S., Fenimore, P. W. & 56 others, Formenty, P., Freiberg, A. N., Garry, R. F., Garza, N. L., Gire, S. K., Gonzalez, J. P., Griffiths, A., Happi, C. T., Hensley, L. E., Herbert, A. S., Hevey, M. C., Hoenen, T., Honko, A. N., Ignatyev, G. M., Jahrling, P. B., Johnson, J. C., Johnson, K. M., Kindrachuk, J., Klenk, H. D., Kobinger, G., Kochel, T. J., Lackemeyer, M. G., Lackner, D. F., Leroy, E. M., Lever, M. S., Mühlberger, E., Netesov, S. V., Olinger, G. G., Omilabu, S. A., Palacios, G., Panchal, R. G., Park, D. J., Patterson, J. L., Paweska, J. T., Peters, C. J., Pettitt, J., Pitt, L., Radoshitzky, S. R., Ryabchikova, E. I., Saphire, E. O., Sabeti, P. C., Sealfon, R., Shestopalov, A. M., Smither, S. J., Sullivan, N. J., Swanepoel, R., Takada, A., Towner, J. S., Van Der Groen, G., Volchkov, V. E., Volchkova, V. A., Wahl-Jensen, V., Warren, T. K., Warfield, K. L., Weidmann, M. & Nichol, S. T., 2014, In : Viruses. 6, 9, p. 3663-3682 20 p.

Research output: Contribution to journalLetter

40 Scopus citations

Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription

Ilinykh, P. A., Tigabu, B., Ivanov, A., Ammosova, T., Obukhov, Y., Garron, T., Kumari, N., Kovalskyy, D., Platonov, M. O., Naumchik, V. S., Freiberg, A. N., Nekhai, S. & Bukreyev, A., Aug 15 2014, In : Journal of Biological Chemistry. 289, 33, p. 22723-22738 16 p.

Research output: Contribution to journalArticle

48 Scopus citations

Virus nomenclature below the species level: A standardized nomenclature for filovirus strains and variants rescued from cDNA

Kuhn, J. H., Bào, Y., Bavari, S., Becker, S., Bradfute, S., Brauburger, K., Rodney Brister, J., Bukreyev, A. A., Caì, Y., Chandran, K., Davey, R. A., Dolnik, O., Dye, J. M., Enterlein, S., Gonzalez, J. P., Formenty, P., Freiberg, A. N., Hensley, L. E., Hoenen, T., Honko, A. N. & 32 others, Ignatyev, G. M., Jahrling, P. B., Johnson, K. M., Klenk, H. D., Kobinger, G., Lackemeyer, M. G., Leroy, E. M., Lever, M. S., Mühlberger, E., Netesov, S. V., Olinger, G. G., Palacios, G., Patterson, J. L., Paweska, J. T., Pitt, L., Radoshitzky, S. R., Ryabchikova, E. I., Saphire, E. O., Shestopalov, A. M., Smither, S. J., Sullivan, N. J., Swanepoel, R., Takada, A., Towner, J. S., van der Groen, G., Volchkov, V. E., Volchkova, V. A., Wahl-Jensen, V., Warren, T. K., Warfield, K. L., Weidmann, M. & Nichol, S. T., May 2014, In : Archives of virology. 159, 5, p. 1229-1237 9 p.

Research output: Contribution to journalArticle

52 Scopus citations
2013

Neonatal antibody responses are attenuated by interferon-γ produced by NK and T cells during RSV infection

Tregoning, J. S., Wang, B. L., McDonald, J. U., Yamaguchi, Y., Harker, J. A., Goritzka, M., Johansson, C., Bukreyev, A., Collins, P. L. & Openshaw, P. J., Apr 2 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 14, p. 5576-5581 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains

Lubaki, N. M., Ilinykh, P., Pietzsch, C., Tigabu, B., Freiberg, A. N., Koup, R. A. & Bukreyev, A., 2013, In : Journal of virology. 87, 22, p. 12506 1 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

Virus nomenclature below the species level: A standardized nomenclature for natural variants of viruses assigned to the family Filoviridae

Kuhn, J. H., Bao, Y., Bavari, S., Becker, S., Bradfute, S., Brister, J. R., Bukreyev, A. A., Chandran, K., Davey, R. A., Dolnik, O., Dye, J. M., Enterlein, S., Hensley, L. E., Honko, A. N., Jahrling, P. B., Johnson, K. M., Kobinger, G., Leroy, E. M., Lever, M. S., Mühlberger, E. & 17 others, Netesov, S. V., Olinger, G. G., Palacios, G., Patterson, J. L., Paweska, J. T., Pitt, L., Radoshitzky, S. R., Saphire, E. O., Smither, S. J., Swanepoel, R., Towner, J. S., van der Groen, G., Volchkov, V. E., Wahl-Jensen, V., Warren, T. K., Weidmann, M. & Nichol, S. T., Jan 1 2013, In : Archives of virology. 158, 1, p. 301-311 11 p.

Research output: Contribution to journalArticle

68 Scopus citations

Virus nomenclature below the species level: A standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae

Kuhn, J. H., Bao, Y., Bavari, S., Becker, S., Bradfute, S., Brister, J. R., Bukreyev, A. A., Caì, Y., Chandran, K., Davey, R. A., Dolnik, O., Dye, J. M., Enterlein, S., Gonzalez, J. P., Formenty, P., Freiberg, A. N., Hensley, L. E., Honko, A. N., Ignatyev, G. M., Jahrling, P. B. & 30 others, Johnson, K. M., Klenk, H. D., Kobinger, G., Lackemeyer, M. G., Leroy, E. M., Lever, M. S., Lofts, L. L., Mühlberger, E., Netesov, S. V., Olinger, G. G., Palacios, G., Patterson, J. L., Paweska, J. T., Pitt, L., Radoshitzky, S. R., Ryabchikova, E. I., Saphire, E. O., Shestopalov, A. M., Smither, S. J., Sullivan, N. J., Swanepoel, R., Takada, A., Towner, J. S., van der Groen, G., Volchkov, V. E., Wahl-Jensen, V., Warren, T. K., Warfield, K. L., Weidmann, M. & Nichol, S. T., Jun 2013, In : Archives of virology. 158, 6, p. 1425-1432 8 p.

Research output: Contribution to journalArticle

38 Scopus citations
2012

The human respiratory syncytial virus nonstructural protein 1 regulates type I and type II interferon pathways

Hastie, M. L., Headlam, M. J., Patel, N. B., Bukreyev, A. A., Buchholz, U. J., Dave, K. A., Norris, E. L., Wright, C. L., Spann, K. M., Collins, P. L. & Gorman, J. J., May 2012, In : Molecular and Cellular Proteomics. 11, 5, p. 108-127 20 p.

Research output: Contribution to journalArticle

38 Scopus citations

The secreted g protein of human respiratory syncytial virus antagonizes antibody-mediated restriction of replication involving macrophages and complement

Bukreyev, A., Yang, L. & Collins, P. L., Oct 2012, In : Journal of virology. 86, 19, p. 10880-10884 5 p.

Research output: Contribution to journalArticle

24 Scopus citations
2011

Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte response

Munir, S., Hillyer, P., le Nouën, C., Buchholz, U. J., Rabin, R. L., Collins, P. L. & Bukreyev, A., Apr 2011, In : PLoS pathogens. 7, 4, e1001336.

Research output: Contribution to journalArticle

78 Scopus citations