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  • Alexander Freiberg
2013

Modeling pre-existing immunity to adenovirus in rodents: Immunological requirements for successful development of a recombinant adenovirus serotype 5-based ebola vaccine

Choi, J. H., Schafer, S. C., Zhang, L., Juelich, T., Freiberg, A. N. & Croyle, M. A., Sep 3 2013, In : Molecular Pharmaceutics. 10, 9, p. 3342-3355 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Rift valley fever virus MP-12 vaccine encoding toscana virus NSs retains neuroinvasiveness in mice

Indran, S. V., Lihoradova, O. A., Phoenix, I., Lokugamage, N., Kalveram, B., Head, J. A., Tigabu, B., Smith, J. K., Zhang, L., Juelich, T. L., Gong, B., Freiberg, A. N. & Ikegami, T., Jul 1 2013, In : Journal of General Virology. 94, PART7, p. 1441-1450 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

The Dominant-negative inhibition of double-stranded RNA-Dependent protein kinase PKR increases the efficacy of rift valley fever virus MP-12 vaccine

Lihoradova, O., Kalveram, B., Indran, S. V., Lokugamage, N., Juelich, T. L., Hill, T. E., Tseng, C. T. K., Gong, B., Fukushi, S., Morikawa, S., Freiberg, A. N. & Ikegami, T., 2013, In : Journal of virology. 87, 22, p. 12507 1 p.

Research output: Contribution to journalComment/debate

The lack of maturation of Ebola virus-infected dendritic cells results from the cooperative effect of at least two viral domains

M.Lubaki, N., Ilinykh, P., Pietzsch, C., Tigabu, B., Freiberg, A. N., Koup, R. A. & Bukreyeva, A., Jul 2013, In : Journal of virology. 87, 13, p. 7471-7485 15 p.

Research output: Contribution to journalArticle

53 Scopus citations

The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains

Lubaki, N. M., Ilinykh, P., Pietzsch, C., Tigabu, B., Freiberg, A. N., Koup, R. A. & Bukreyev, A., 2013, In : Journal of virology. 87, 22, p. 12506 1 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

Virus nomenclature below the species level: A standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae

Kuhn, J. H., Bao, Y., Bavari, S., Becker, S., Bradfute, S., Brister, J. R., Bukreyev, A. A., Caì, Y., Chandran, K., Davey, R. A., Dolnik, O., Dye, J. M., Enterlein, S., Gonzalez, J. P., Formenty, P., Freiberg, A. N., Hensley, L. E., Honko, A. N., Ignatyev, G. M., Jahrling, P. B. & 30 others, Johnson, K. M., Klenk, H. D., Kobinger, G., Lackemeyer, M. G., Leroy, E. M., Lever, M. S., Lofts, L. L., Mühlberger, E., Netesov, S. V., Olinger, G. G., Palacios, G., Patterson, J. L., Paweska, J. T., Pitt, L., Radoshitzky, S. R., Ryabchikova, E. I., Saphire, E. O., Shestopalov, A. M., Smither, S. J., Sullivan, N. J., Swanepoel, R., Takada, A., Towner, J. S., van der Groen, G., Volchkov, V. E., Wahl-Jensen, V., Warren, T. K., Warfield, K. L., Weidmann, M. & Nichol, S. T., Jun 2013, In : Archives of virology. 158, 6, p. 1425-1432 8 p.

Research output: Contribution to journalArticle

39 Scopus citations
2012

An assembly model of Rift Valley fever virus

Rusu, M., Bonneau, R., Holbrook, M. R., Watowich, S. J., Birmanns, S., Wriggers, W. & Freiberg, A. N., 2012, In : Frontiers in Microbiology. 3, JUL

Research output: Contribution to journalArticle

25 Scopus citations

A single sublingual dose of an adenovirus-based vaccine protects against lethal ebola challenge in mice and guinea pigs

Choi, J. H., Schafer, S. C., Zhang, L., Kobinger, G. P., Juelich, T., Freiberg, A. N. & Croyle, M. A., Jan 1 2012, In : Molecular Pharmaceutics. 9, 1, p. 156-167 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Chemotactic and inflammatory responses in the liver and brain are associated with pathogenesis of rift valley fever virus infection in the mouse

Gray, K. K., Worthy, M. N., Juelich, T. L., Agar, S. L., Poussard, A., Ragland, D., Freiberg, A. N. & Holbrook, M. R., Feb 2012, In : PLoS neglected tropical diseases. 6, 2, e1529.

Research output: Contribution to journalArticle

30 Scopus citations

Detection of severe fever with thrombocytopenia syndrome virus by reverse transcription-cross-priming amplification coupled with vertical flow visualization

Cui, L., Ge, Y., Qi, X., Xu, G., Li, H., Zhao, K., Wu, B., Shi, Z., Guo, X., Hu, L., You, Q., Zhang, L. H., Freiberg, A. N., Yu, X., Wang, H., Zhou, M. & Tang, Y. W., Dec 2012, In : Journal of Clinical Microbiology. 50, 12, p. 3881-3885 5 p.

Research output: Contribution to journalArticle

54 Scopus citations

Genetic subpopulations of rift valley fever virus strains ZH548 and MP-12 and recombinant MP-12 strains

Lokugamage, N., Freiberg, A. N., Morrill, J. C. & Ikegami, T., Dec 2012, In : Journal of virology. 86, 24, p. 13566-13575 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Mutational analysis of positively charged amino acid residues of Uukuniemi phlebovirus nucleocapsid protein

Katz, A., Freiberg, A. N., Backström, V., Holm, L., Vaheri, A., Flick, R. & Plyusnin, A., Jul 1 2012, In : Virus Research. 167, 1, p. 118-123 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Recent progress in henipavirus research: Molecular biology, genetic diversity, animal models

Rockx, B., Winegar, R. & Freiberg, A. N., Aug 1 2012, In : Antiviral research. 95, 2, p. 135-149 15 p.

Research output: Contribution to journalReview article

33 Scopus citations

The dominant-negative inhibition of double-stranded RNA-dependent protein kinase PKR increases the efficacy of rift valley fever virus MP-12 vaccine

Lihoradova, O., Kalveram, B., Indran, S. V., Lokugamage, N., Juelich, T. L., Hill, T. E., Tseng, C. T. K., Gong, B., Fukushi, S., Morikawa, S., Freiberg, A. N. & Ikegami, T., Jul 2012, In : Journal of virology. 86, 14, p. 7650-7661 12 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011

Differential cytokine responses from primary human Kupffer cells following infection with wild-type or vaccine strain yellow fever virus

Woodson, S. E., Freiberg, A. N. & Holbrook, M. R., Mar 30 2011, In : Virology. 412, 1, p. 188-195 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Inactivated or live-attenuated bivalent vaccines that confer protection against rabies and Ebola viruses

Blaney, J. E., Wirblich, C., Papaneri, A. B., Johnson, R. F., Myers, C. J., Juelich, T. L., Holbrook, M. R., Freiberg, A. N., Bernbaum, J. G., Jahrling, P. B., Paragas, J. & Schnell, M. J., Oct 2011, In : Journal of virology. 85, 20, p. 10605-10616 12 p.

Research output: Contribution to journalArticle

58 Scopus citations

Recombinant Rift Valley fever vaccines induce protective levels of antibody in baboons and resistance to lethal challenge in mice

Papin, J. F., Verardi, P. H., Jones, L. A., Monge-Navarro, F., Brault, A. C., Holbrook, M. R., Worthy, M. N., Freiberg, A. N. & Yilma, T. D., Sep 6 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 36, p. 14926-14931 6 p.

Research output: Contribution to journalArticle

32 Scopus citations

T-705 (favipiravir) inhibition of arenavirus replication in cell culture

Mendenhall, M., Russell, A., Juelich, T., Messina, E. L., Smee, D. F., Freiberg, A. N., Holbrook, M. R., Furuta, Y., De La Torre, J. C., Nunberg, J. H. & Gowen, B. B., Feb 2011, In : Antimicrobial agents and chemotherapy. 55, 2, p. 782-787 6 p.

Research output: Contribution to journalArticle

59 Scopus citations