Find Research Outputs

Search results

• 2018

  Cystatins 9 and C as a novel immunotherapy treatment that protects against multidrug-resistant New Delhi metallo-beta-lactamase-1-producing klebsiella pneumoniae

  Holloway, A. J., Yu, J. J., Arulanandam, B. P., Hoskinson, S. M. & Eaves-Pyles, T., Mar 2018, In: Antimicrobial agents and chemotherapy. 62, 3, e01900-17.

  Research output: Contribution to journal › Article › peer-review

  • beta-lactamase NDM-1
  • Cystatins
  • Klebsiella pneumoniae
  • Immunotherapy
  • Bacterial Pneumonia
  6 Scopus citations

• GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3

  Zhao, Y., Chen, F., Wu, W., Sun, M., Bilotta, A. J., Yao, S., Xiao, Y., Huang, X., Eaves-Pyles, T. D., Golovko, G., Fofanov, Y., D'Souza, W., Zhao, Q., Liu, Z. & Cong, Y., May 1 2018, In: Mucosal Immunology. 11, 3, p. 752-762 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Volatile Fatty Acids
  • Microbiota
  • Defensins
  • Epithelial Cells
  • Peptides
  66 Scopus citations
• 2016

  Intraluminal flagellin differentially contributes to gut dysbiosis and systemic inflammation following burn injury

  Grimes, L., Doyle, A., Miller, A. L., Pyles, R. B., Olah, G., Szabo, C., Hoskins, S. & Eaves-Pyles, T., Dec 2016, In: PloS one. 11, 12, e0166770.

  Research output: Contribution to journal › Article › peer-review

  • burns (injuries)
  • dysbiosis
  • Flagellin
  • Dysbiosis
  • flagellin
  7 Scopus citations

• M-cells contribute to the entry of an oral vaccine but are not essential for the subsequent induction of protective immunity against Francisella tularensis

  Cunningham, A. L., Guentzel, M. N., Yu, J. J., Hung, C. Y., Forsthuber, T. G., Navara, C. S., Yagita, H., Williams, I. R., Klose, K. E., Eaves-Pyles, T. D. & Arulanandam, B. P., Apr 2016, In: PloS one. 11, 4, e0153402.

  Research output: Contribution to journal › Article › peer-review

  • Francisella tularensis
  • immunity
  • vaccines
  • oral vaccination
  • Immunity
  3 Scopus citations
• 2013

  Immunomodulatory and antibacterial effects of cystatin 9 against Francisella tularensis

  Eaves-Pyles, T., Patel, J., Arigi, E., Cong, Y., Cao, A., Garg, N., Dhiman, M., Pyles, R. B., Arulanandam, B., Miller, A. L., Popov, V. L., Soong, L., Carlsen, E. D., Coletta, C., Szabo, C. & Almeida, I. C., 2013, In: Molecular Medicine. 19, 1, p. 263-275 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystatins
  • Francisella tularensis
  • Macrophages
  • Cysteine Proteinase Inhibitors
  • Phagosomes
  7 Scopus citations
• 2012

  Burkholderia mallei and Burkholderia pseudomallei stimulate differential inflammatory responses from human alveolar type II cells (ATII) and macrophages.

  Lu, R., Popov, V., Patel, J. & Eaves-Pyles, T., 2012, In: Frontiers in Cellular and Infection Microbiology. 2, p. 165 1 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Burkholderia mallei
  • Burkholderia pseudomallei
  • Alveolar Epithelial Cells
  • Alveolar Macrophages
  • Macrophages
  10 Scopus citations

• Commensal bacteria modulate innate immune responses of vaginal epithelial cell multilayer cultures

  Rose, W. A., McGowin, C. L., Spagnuolo, R. A., Eaves-Pyles, T. D., Popov, V. L. & Pyles, R. B., Mar 7 2012, In: PloS one. 7, 3, e32728.

  Research output: Contribution to journal › Article › peer-review

  • Epithelial Cells
  • Bacteria
  • innate immunity
  • Multilayers
  • Innate Immunity
  68 Scopus citations