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• 2020

  Acupuncture Reduces Hypertrophy and Cardiac Fibrosis, and Improves Heart Function in Mice with Diabetic Cardiomyopathy

  Ye, Y., Birnbaum, Y., Widen, S. G., Zhang, Z., Zhu, S., Bajaj, M. & Chen, H., Dec 2020, In: Cardiovascular Drugs and Therapy. 34, 6, p. 835-848 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Diabetic Cardiomyopathies
  • Acupuncture
  • Interleukin-1
  • Fibrosis
  • Somatomedin Receptors

• Dapagliflozin and Ticagrelor Have Additive Effects on the Attenuation of the Activation of the NLRP3 Inflammasome and the Progression of Diabetic Cardiomyopathy: an AMPK–mTOR Interplay

  Chen, H., Tran, D., Yang, H. C., Nylander, S., Birnbaum, Y. & Ye, Y., Aug 1 2020, In: Cardiovascular Drugs and Therapy. 34, 4, p. 443-461 19 p.

  Research output: Contribution to journal › Article › peer-review

  • 2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol
  • NLR Proteins
  • Ticagrelor
  • Diabetic Cardiomyopathies
  • Inflammasomes
  4 Scopus citations

• Does Inhibition of Nuclear Factor Kappa B Explain the Protective Effect of Ticagrelor on Myocardial Ischemia-Reperfusion Injury?

  Birnbaum, Y., Ye, Y. & Perez-Polo, J. R., Feb 1 2020, In: Journal of cardiovascular pharmacology. 75, 2, p. 108-111 4 p.

  Research output: Contribution to journal › Article › peer-review
• 2019

  DPP-4 inhibition by linagliptin prevents cardiac dysfunction and inflammation by targeting the Nlrp3/ASC inflammasome

  Birnbaum, Y., Tran, D., Bajaj, M. & Ye, Y., Sep 1 2019, In: Basic Research in Cardiology. 114, 5, 35.

  Research output: Contribution to journal › Article › peer-review

  • Linagliptin
  • Inflammasomes
  • Flax
  • Inflammation
  • Infarction
  11 Scopus citations

• The Role of Non-coding RNAs in Ischemic Myocardial Reperfusion Injury

  Siebert, V., Allencherril, J., Ye, Y., Wehrens, X. H. T. & Birnbaum, Y., Aug 15 2019, In: Cardiovascular Drugs and Therapy. 33, 4, p. 489-498 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Myocardial Reperfusion Injury
  • Untranslated RNA
  • MicroRNAs
  • Ischemia
  • Reperfusion
  7 Scopus citations

• Ticagrelor Improves Remodeling, Reduces Apoptosis, Inflammation and Fibrosis and Increases the Number of Progenitor Stem Cells After Myocardial Infarction in a Rat Model of Ischemia Reperfusion

  Birnbaum, Y., Tran, D., Chen, H., Nylander, S., Sampaio, L. C. & Ye, Y., Jan 1 2019, In: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 53, 6, p. 961-981 21 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ticagrelor
  • Reperfusion
  • Ischemia
  • Fibrosis
  • Stem Cells
  6 Scopus citations
• 2018

  Circulating miRNA Expression Profiling and Target Prediction in Patients Receiving Dexmedetomidine

  Yang, X., Chen, H., Chen, Y., Birnbaum, Y., Liang, R., Ye, Y. & Qian, J., Oct 1 2018, In: Cellular Physiology and Biochemistry. 50, 2, p. 569-584 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Dexmedetomidine
  • MicroRNAs
  • human MIRN101 microRNA
  • Human Mirn140 microRNA
  • human MIRN150 microRNA
  5 Scopus citations

• Combined SGLT2 and DPP4 Inhibition Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Nephropathy in Mice with Type 2 Diabetes

  Birnbaum, Y., Bajaj, M., Yang, H. C. & Ye, Y., Apr 1 2018, In: Cardiovascular Drugs and Therapy. 32, 2, p. 135-145 11 p.

  Research output: Contribution to journal › Article › peer-review

  • 2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol
  • Inflammasomes
  • Diabetic Nephropathies
  • saxagliptin
  • Type 2 Diabetes Mellitus
  29 Scopus citations

• Dapagliflozin Attenuates Na⁺/H⁺ Exchanger-1 in Cardiofibroblasts via AMPK Activation

  Ye, Y., Jia, X., Bajaj, M. & Birnbaum, Y., Dec 1 2018, In: Cardiovascular Drugs and Therapy. 32, 6, p. 553-558 6 p.

  Research output: Contribution to journal › Article › peer-review

  • 2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol
  • Sodium-Hydrogen Exchanger 1
  • Adenosine Kinase
  • Adenosine Monophosphate
  • HSP70 Heat-Shock Proteins
  20 Scopus citations

• Expression Profiling of Circular RNAs and Micrornas in Heart Tissue of Mice with Alcoholic Cardiomyopathy

  Yang, Y., Chen, H., Ding, N., Wang, S., Duan, Z., Birnbaum, Y., Ye, Y. & Qian, J., May 1 2018, In: Cellular Physiology and Biochemistry. 46, 6, p. 2284-2296 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Alcoholic Cardiomyopathy
  • circular RNA
  • MicroRNAs
  • Heart
  • Untranslated RNA
  7 Scopus citations

• GLP-1 Receptor Agonists and Cardiovascular Disease: a Meta-Analysis of Recent Cardiac Outcome Trials

  Jia, X., Alam, M., Ye, Y., Bajaj, M. & Birnbaum, Y., Feb 1 2018, In: Cardiovascular Drugs and Therapy. 32, 1, p. 65-72 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Glucagon-Like Peptide-1 Receptor
  • Meta-Analysis
  • Cardiovascular Diseases
  • Mortality
  • Hypoglycemic Agents
  17 Scopus citations

• SGLT2 Inhibitors and Cardiovascular Outcomes: Current Perspectives and Future Potentials

  Jia, X., Mehta, P. B., Ye, Y., Alam, M., Birnbaum, Y. & Bajaj, M., Sep 1 2018, In: Current Diabetes Reports. 18, 9, 63.

  Research output: Contribution to journal › Review article › peer-review

  • Sodium-Glucose Transporter 2 Inhibitors
  • Sodium-Glucose Transport Proteins
  • Sodium-Hydrogen Exchangers
  • Publications
  • Atherosclerosis
  5 Scopus citations

• Size matters in STEMI: time for translation of ticagrelor?

  Birnbaum, Y. & Ye, Y., Dec 1 2018, In: Cardiovascular Research. 114, 14, p. 1817-1818 2 p.

  Research output: Contribution to journal › Article › peer-review
• 2015

  Statin-Induced Cardioprotection Against Ischemia-Reperfusion Injury: Potential Drug-Drug Interactions. Lesson to be Learnt by Translating Results from Animal Models to the Clinical Settings

  Birnbaum, G. D., Birnbaum, I., Ye, Y. & Birnbaum, Y., Aug 25 2015, In: Cardiovascular Drugs and Therapy. 29, 5, p. 461-467 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Drug Interactions
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Animal Models
  • Masks
  • Clinical Trials
  16 Scopus citations

• Ticagrelor protects the heart against reperfusion injury and improves remodeling after myocardial infarction

  Ye, Y., Birnbaum, G. D., Perez-Polo, J. R., Nanhwan, M. K., Nylander, S. & Birnbaum, Y., Aug 25 2015, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 8, p. 1805-1814 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ticagrelor
  • Clopidogrel
  • Myocardial Infarction
  • Heart
  • Reperfusion
  69 Scopus citations
• 2014

  Chronic treatment with ticagrelor limits myocardial infarct size: An adenosine and cyclooxygenase-2-dependent effect

  Nanhwan, M. K., Ling, S., Kodakandla, M., Nylander, S., Ye, Y. & Birnbaum, Y., Sep 2014, In: Arteriosclerosis, thrombosis, and vascular biology. 34, 9, p. 2078-2085 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ticagrelor
  • Cyclooxygenase 2
  • Adenosine
  • Clopidogrel
  • Myocardial Infarction
  99 Scopus citations

• Dipeptidyl peptidase IV inhibitors and ischemic myocardial injury

  Yoon, A. H., Ye, Y. & Birnbaum, Y., Sep 2014, In: Journal of Cardiovascular Pharmacology and Therapeutics. 19, 5, p. 417-425 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dipeptidyl-Peptidase IV Inhibitors
  • Wounds and Injuries
  • Glucagon-Like Peptide 1
  • Clinical Trials
  • Hypoglycemic Agents
  7 Scopus citations

• PTEN Upregulation May Explain the Development of Insulin Resistance and Type 2 Diabetes with High Dose Statins

  Birnbaum, Y., Nanhwan, M. K., Ling, S., Perez-Polo, J. R., Ye, Y. & Bajaj, M., Oct 2014, In: Cardiovascular Drugs and Therapy. 28, 5, p. 447-457 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Rosuvastatin Calcium
  • Western Diet
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Insulin Resistance
  • Type 2 Diabetes Mellitus
  23 Scopus citations